MeSH term | MeSH ID | Detail |
---|---|---|
Alzheimer Disease | D000544 | 76 associated lipids |
Adenocarcinoma | D000230 | 166 associated lipids |
18194-24-6 is a lipid of Glycerophospholipids (GP) class. 18194-24-6 is associated with abnormalities such as Cerebrovascular accident, Renal tubular disorder, Atherosclerosis, Hyperlipoproteinemia Type III and Lipid Metabolism Disorders. The involved functions are known as Process, protein folding, Catalyst, Biochemical Pathway and Fold in Medical Device Material. 18194-24-6 often locates in Tissue membrane, Membrane, periplasm, vesicle membrane and outer membrane. The associated genes with 18194-24-6 are Integral Membrane Proteins, Protein Structure, RTN4 gene, RTN4R gene and Protein, Organized by Structure. The related lipids are Micelles, dimyristoylphosphatidylglycerol, 1,2-dihexadecyl-sn-glycero-3-phosphocholine, Unilamellar Vesicles and cholesteryl oleate. The related experimental models are Mouse Model, Arthritis, Adjuvant-Induced, Disease model and Xenograft Model.
To understand associated biological information of 18194-24-6, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
18194-24-6 is suspected in Atherosclerosis, Cardiovascular Diseases, Dehydration, Abnormal shape, Renal tubular disorder, Hyperlipoproteinemia Type III and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with 18194-24-6
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'Association of a model class A (apolipoprotein) amphipathic alpha helical peptide with lipid: high resolution NMR studies of peptide.lipid discoidal complexes.' (Mishra VK et al., 2006).
Arthritis, Adjuvant-Induced are used in the study 'T cell antigen receptor peptide-lipid membrane interactions using surface plasmon resonance.' (Bender V et al., 2004).
Disease model are used in the study 'Kupffer cells do not play a role in governing the efficacy of liposomal mitoxantrone used to treat a tumor model designed to assess drug delivery to liver.' (Lim HJ et al., 2000).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Abbott GW et al. | Interaction between soluble and membrane-embedded potassium channel peptides monitored by Fourier transform infrared spectroscopy. | 2012 | PLoS ONE | pmid:23145073 |
Jo S et al. | Automated builder and database of protein/membrane complexes for molecular dynamics simulations. | 2007 | PLoS ONE | pmid:17849009 |
Bertelsen K et al. | Mechanisms of peptide-induced pore formation in lipid bilayers investigated by oriented 31P solid-state NMR spectroscopy. | 2012 | PLoS ONE | pmid:23094079 |
Vilches S et al. | Neurotoxicity of prion peptides mimicking the central domain of the cellular prion protein. | 2013 | PLoS ONE | pmid:23940658 |
Shrivastava S and Schneider MF | Opto-mechanical coupling in interfaces under static and propagative conditions and its biological implications. | 2013 | PLoS ONE | pmid:23861769 |
Lek MT et al. | Swapping the N- and C-terminal domains of human apolipoprotein E3 and AI reveals insights into their structure/activity relationship. | 2017 | PLoS ONE | pmid:28644829 |
Pavlidou M et al. | Nanodiscs allow phage display selection for ligands to non-linear epitopes on membrane proteins. | 2013 | PLoS ONE | pmid:24039747 |
Sontag TJ and Reardon CA | Polymorphisms of mouse apolipoprotein A-II alter its physical and functional nature. | 2014 | PLoS ONE | pmid:24520415 |
Fischer NO et al. | Evaluation of nanolipoprotein particles (NLPs) as an in vivo delivery platform. | 2014 | PLoS ONE | pmid:24675794 |
Sankhala RS et al. | Correlation of membrane binding and hydrophobicity to the chaperone-like activity of PDC-109, the major protein of bovine seminal plasma. | 2011 | PLoS ONE | pmid:21408153 |
Anbazhagan V et al. | Isothermal titration calorimetric studies on the interaction of the major bovine seminal plasma protein, PDC-109 with phospholipid membranes. | 2011 | PLoS ONE | pmid:22022488 |
Wallgren M et al. | Reconstitution of the anti-apoptotic Bcl-2 protein into lipid membranes and biophysical evidence for its detergent-driven association with the pro-apoptotic Bax protein. | 2013 | PLoS ONE | pmid:23626686 |
Watnick PI et al. | Characterization of the transverse relaxation rates in lipid bilayers. | 1990 | Proc. Natl. Acad. Sci. U.S.A. | pmid:2315304 |
Pieta P et al. | Direct visualization of the alamethicin pore formed in a planar phospholipid matrix. | 2012 | Proc. Natl. Acad. Sci. U.S.A. | pmid:23236158 |
Herscovitz H et al. | Expression, secretion, and lipid-binding characterization of the N-terminal 17% of apolipoprotein B. | 1991 | Proc. Natl. Acad. Sci. U.S.A. | pmid:1871138 |
Vasudevan SV et al. | Protein folding at the membrane interface, the structure of Nogo-66 requires interactions with a phosphocholine surface. | 2010 | Proc. Natl. Acad. Sci. U.S.A. | pmid:20351248 |
Mateo CR and Douhal A | A coupled proton-transfer and twisting-motion fluorescence probe for lipid bilayers. | 1998 | Proc. Natl. Acad. Sci. U.S.A. | pmid:9636133 |
Popp CA and Hyde JS | Electron-electron double resonance and saturation-recovery studies of nitroxide electron and nuclear spin-lattice relaxation times and Heisenberg exchange rates: lateral diffusion in dimyristoyl phosphatidylcholine. | 1982 | Proc. Natl. Acad. Sci. U.S.A. | pmid:6283533 |
Radhakrishnan A and McConnell HM | Electric field effect on cholesterol-phospholipid complexes. | 2000 | Proc. Natl. Acad. Sci. U.S.A. | pmid:10655486 |
Kalyanaraman B et al. | Photodynamic action of merocyanine 540 on artificial and natural cell membranes: involvement of singlet molecular oxygen. | 1987 | Proc. Natl. Acad. Sci. U.S.A. | pmid:3033673 |