MeSH term | MeSH ID | Detail |
---|---|---|
Lung Neoplasms | D008175 | 171 associated lipids |
Body Weight | D001835 | 333 associated lipids |
18194-24-6 is a lipid of Glycerophospholipids (GP) class. 18194-24-6 is associated with abnormalities such as Cerebrovascular accident, Renal tubular disorder, Atherosclerosis, Hyperlipoproteinemia Type III and Lipid Metabolism Disorders. The involved functions are known as Process, protein folding, Catalyst, Biochemical Pathway and Fold in Medical Device Material. 18194-24-6 often locates in Tissue membrane, Membrane, periplasm, vesicle membrane and outer membrane. The associated genes with 18194-24-6 are Integral Membrane Proteins, Protein Structure, RTN4 gene, RTN4R gene and Protein, Organized by Structure. The related lipids are Micelles, dimyristoylphosphatidylglycerol, 1,2-dihexadecyl-sn-glycero-3-phosphocholine, Unilamellar Vesicles and cholesteryl oleate. The related experimental models are Mouse Model, Arthritis, Adjuvant-Induced, Disease model and Xenograft Model.
To understand associated biological information of 18194-24-6, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
18194-24-6 is suspected in Atherosclerosis, Cardiovascular Diseases, Dehydration, Abnormal shape, Renal tubular disorder, Hyperlipoproteinemia Type III and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with 18194-24-6
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
Mouse Model are used in the study 'Association of a model class A (apolipoprotein) amphipathic alpha helical peptide with lipid: high resolution NMR studies of peptide.lipid discoidal complexes.' (Mishra VK et al., 2006).
Arthritis, Adjuvant-Induced are used in the study 'T cell antigen receptor peptide-lipid membrane interactions using surface plasmon resonance.' (Bender V et al., 2004).
Disease model are used in the study 'Kupffer cells do not play a role in governing the efficacy of liposomal mitoxantrone used to treat a tumor model designed to assess drug delivery to liver.' (Lim HJ et al., 2000).
Model | Cross reference | Weighted score | Related literatures |
---|
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Tremouilhac P et al. | Synergistic transmembrane alignment of the antimicrobial heterodimer PGLa/magainin. | 2006 | J. Biol. Chem. | pmid:16877761 |
Raussens V et al. | The low density lipoprotein receptor active conformation of apolipoprotein E. Helix organization in n-terminal domain-phospholipid disc particles. | 1998 | J. Biol. Chem. | pmid:9748256 |
Ledford AS et al. | Self-association and lipid binding properties of the lipoprotein initiating domain of apolipoprotein B. | 2006 | J. Biol. Chem. | pmid:16407215 |
Surewicz WK et al. | Human apolipoprotein A-I forms thermally stable complexes with anionic but not with zwitterionic phospholipids. | 1986 | J. Biol. Chem. | pmid:3097001 |
Teng Q and Scarlata S | Effect of high pressure on the association of melittin to membranes. | 1993 | J. Biol. Chem. | pmid:8509383 |
Gómez-Fernández JC et al. | A fluorescence quenching study of tryptophanyl residues of (Ca2+ + Mg2+)-ATPase from sarcoplasmic reticulum. | 1985 | J. Biol. Chem. | pmid:3158653 |
Dankert JR et al. | On a domain structure of colicin E1. A COOH-terminal peptide fragment active in membrane depolarization. | 1982 | J. Biol. Chem. | pmid:7037787 |
Reardon CA et al. | Expression of the human apolipoprotein E gene in cultured mammalian cells. | 1986 | J. Biol. Chem. | pmid:3733697 |
Epand RM et al. | Structural analysis and amphiphilic properties of a chemically synthesized mitochondrial signal peptide. | 1986 | J. Biol. Chem. | pmid:3733699 |
Rifici VA and Eder HA | A hepatocyte receptor for high-density lipoproteins specific for apolipoprotein A-I. | 1984 | J. Biol. Chem. | pmid:6094531 |
Argyri L et al. | Molecular basis for increased risk for late-onset Alzheimer disease due to the naturally occurring L28P mutation in apolipoprotein E4. | 2014 | J. Biol. Chem. | pmid:24644280 |
Fraser PE and Deber CM | Surface accessibility of 13C-labeled lysine residues in membrane-bound myelin basic protein. | 1984 | J. Biol. Chem. | pmid:6204974 |
Sriwimol W et al. | Potential Prepore Trimer Formation by the Bacillus thuringiensis Mosquito-specific Toxin: MOLECULAR INSIGHTS INTO A CRITICAL PREREQUISITE OF MEMBRANE-BOUND MONOMERS. | 2015 | J. Biol. Chem. | pmid:26112409 |
Dornmair K et al. | Fast measurement of galactoside transport by lactose permease. | 1989 | J. Biol. Chem. | pmid:2642475 |
Terui T et al. | Effects of acid phospholipids on nucleotide exchange properties of ADP-ribosylation factor 1. Evidence for specific interaction with phosphatidylinositol 4,5-bisphosphate. | 1994 | J. Biol. Chem. | pmid:7961749 |
Emmanuel F et al. | Identification of specific amphipathic alpha-helical sequence of human apolipoprotein A-IV involved in lecithin:cholesterol acyltransferase activation. | 1994 | J. Biol. Chem. | pmid:7961983 |
Randazzo PA et al. | Activation of ADP-ribosylation factor by Golgi membranes. Evidence for a brefeldin A- and protease-sensitive activating factor on Golgi membranes. | 1993 | J. Biol. Chem. | pmid:8486645 |
Lu B et al. | Conformational reorganization of the four-helix bundle of human apolipoprotein E in binding to phospholipid. | 2000 | J. Biol. Chem. | pmid:10801877 |
Klezovitch O et al. | Structural determinants in the C-terminal domain of apolipoprotein E mediating binding to the protein core of human aortic biglycan. | 2000 | J. Biol. Chem. | pmid:10751422 |
Innerarity TL et al. | Normalization of receptor binding of apolipoprotein E2. Evidence for modulation of the binding site conformation. | 1984 | J. Biol. Chem. | pmid:6327714 |
Gould RJ et al. | Lipid effects on the binding properties of a reconstituted insulin receptor. | 1982 | J. Biol. Chem. | pmid:7053382 |
Davidson WS et al. | The influence of apolipoprotein structure on the efflux of cellular free cholesterol to high density lipoprotein. | 1994 | J. Biol. Chem. | pmid:8083197 |
Bienvenue A et al. | Evidence for protein-associated lipids from deuterium nuclear magnetic resonance studies of rhodopsin-dimyristoylphosphatidylcholine recombinants. | 1982 | J. Biol. Chem. | pmid:7061462 |
Raj PA et al. | Membrane-induced helical conformation of an active candidacidal fragment of salivary histatins. | 1994 | J. Biol. Chem. | pmid:8144548 |
Ross AH et al. | The transmembrane domain of glycophorin A as studied by cross-linking using photoactivatable phospholipids. | 1982 | J. Biol. Chem. | pmid:7068629 |
Surewicz WK et al. | Secondary structure of the hydrophobic myelin protein in a lipid environment as determined by Fourier-transform infrared spectrometry. | 1987 | J. Biol. Chem. | pmid:3597388 |
Dickson PW et al. | Thyroxine transport in choroid plexus. | 1987 | J. Biol. Chem. | pmid:3654646 |
Yang E and Huestis WH | Oxidative interactions between the erythrocyte membrane and phosphatidylcholine vesicles. | 1994 | J. Biol. Chem. | pmid:8182058 |
Wang Y et al. | Identification of shallow and deep membrane-penetrating forms of diphtheria toxin T domain that are regulated by protein concentration and bilayer width. | 1997 | J. Biol. Chem. | pmid:9312118 |
Beckstead JA et al. | The C terminus of apolipoprotein A-V modulates lipid-binding activity. | 2007 | J. Biol. Chem. | pmid:17401142 |
Wientzek M et al. | Binding of insect apolipophorin III to dimyristoylphosphatidylcholine vesicles. Evidence for a conformational change. | 1994 | J. Biol. Chem. | pmid:8308032 |
Greenhalgh DA et al. | Hydrophobic amino acids in the retinal-binding pocket of bacteriorhodopsin. | 1993 | J. Biol. Chem. | pmid:8376389 |
Mishra VK et al. | Effect of leucine to phenylalanine substitution on the nonpolar face of a class A amphipathic helical peptide on its interaction with lipid: high resolution solution NMR studies of 4F-dimyristoylphosphatidylcholine discoidal complex. | 2008 | J. Biol. Chem. | pmid:18845546 |
Steinmetz A and Utermann G | Activation of lecithin: cholesterol acyltransferase by human apolipoprotein A-IV. | 1985 | J. Biol. Chem. | pmid:3918999 |
Surrey T and Jähnig F | Kinetics of folding and membrane insertion of a beta-barrel membrane protein. | 1995 | J. Biol. Chem. | pmid:7499313 |
Oldfield E et al. | Deuterium NMR of specifically deuterated fluorine spin probes. | 1980 | J. Biol. Chem. | pmid:7440561 |
Lund-Katz S et al. | Conformation of apolipoprotein E in lipoproteins. | 1993 | J. Biol. Chem. | pmid:8226815 |
Strittmatter P et al. | Interaction of non-myristoylated NADH-cytochrome b5 reductase with cytochrome b5-dimyristoylphosphatidylcholine vesicles. | 1993 | J. Biol. Chem. | pmid:8226835 |
Hwang J and Menon KM | Binding of apolipoprotein A-I and A-II after recombination with phospholipid vesicles to the high density lipoprotein receptor of luteinized rat ovary. | 1985 | J. Biol. Chem. | pmid:2985608 |
Martin JD et al. | Structure and membrane affinity of new amphiphilic siderophores produced by Ochrobactrum sp. SP18. | 2006 | J. Biol. Inorg. Chem. | pmid:16791646 |
Paradiso P et al. | Drug release from liposome coated hydrogels for soft contact lenses: the blinking and temperature effect. | 2017 | J. Biomed. Mater. Res. Part B Appl. Biomater. | pmid:27192551 |
Hsieh YH and Chou CY | Structural and functional characterization of human apolipoprotein E 72-166 peptides in both aqueous and lipid environments. | 2011 | J. Biomed. Sci. | pmid:21219628 |
Zandomeneghi G et al. | NMR of bicelles: orientation and mosaic spread of the liquid-crystal director under sample rotation. | 2003 | J. Biomol. NMR | pmid:12652120 |
Zandomeneghi G et al. | Switched-angle spinning applied to bicelles containing phospholipid-associated peptides. | 2003 | J. Biomol. NMR | pmid:12652121 |
Chou JJ et al. | Characterization of phospholipid mixed micelles by translational diffusion. | 2004 | J. Biomol. NMR | pmid:15213428 |
Bárány-Wallje E et al. | Dynamics of transportan in bicelles is surface charge dependent. | 2006 | J. Biomol. NMR | pmid:16705358 |
Ottiger M and Bax A | Bicelle-based liquid crystals for NMR-measurement of dipolar couplings at acidic and basic pH values. | 1999 | J. Biomol. NMR | pmid:10070759 |
Mesleh MF et al. | Myristoylation as a general method for immobilization and alignment of soluble proteins for solid-state NMR structural studies. | 2003 | J. Biomol. NMR | pmid:12566999 |
Soubias O et al. | High resolution 13C NMR spectra on oriented lipid bilayers: from quantifying the various sources of line broadening to performing 2D experiments with 0.2-0.3 ppm resolution in the carbon dimension. | 2002 | J. Biomol. NMR | pmid:12449415 |
Todokoro Y et al. | Structure analysis of membrane-reconstituted subunit c-ring of E. coli H+-ATP synthase by solid-state NMR. | 2010 | J. Biomol. NMR | pmid:20596883 |
Lancelot N et al. | Applications of variable-angle sample spinning experiments to the measurement of scaled residual dipolar couplings and 15N CSA in soluble proteins. | 2005 | J. Biomol. NMR | pmid:16331420 |
Bax A and Tjandra N | High-resolution heteronuclear NMR of human ubiquitin in an aqueous liquid crystalline medium. | 1997 | J. Biomol. NMR | pmid:9390407 |
Bayer P et al. | Refinement of the structure of protein-RNA complexes by residual dipolar coupling analysis. | 1999 | J. Biomol. NMR | pmid:10427742 |
Ottiger M and Bax A | Characterization of magnetically oriented phospholipid micelles for measurement of dipolar couplings in macromolecules. | 1998 | J. Biomol. NMR | pmid:9835045 |
Losonczi JA and Prestegard JH | Improved dilute bicelle solutions for high-resolution NMR of biological macromolecules. | 1998 | J. Biomol. NMR | pmid:9835051 |
Tian F et al. | Sign determination of dipolar couplings in field-oriented bicelles by variable angle sample spinning (VASS). | 1999 | J. Biomol. NMR | pmid:10605087 |
Brunner E et al. | Pressure-stability of phospholipid bicelles: measurement of residual dipolar couplings under extreme conditions. | 2001 | J. Biomol. NMR | pmid:11727981 |
Salgado J et al. | Membrane-bound structure and alignment of the antimicrobial beta-sheet peptide gramicidin S derived from angular and distance constraints by solid state 19F-NMR. | 2001 | J. Biomol. NMR | pmid:11775737 |
Tsui V et al. | Assessment of zinc finger orientations by residual dipolar coupling constants. | 2000 | J. Biomol. NMR | pmid:10718608 |
Fu Y and Wand AJ | Partial alignment and measurement of residual dipolar couplings of proteins under high hydrostatic pressure. | 2013 | J. Biomol. NMR | pmid:23807390 |
Garnier N et al. | Molecular dynamics simulations of the transmembrane domain of the oncogenic ErbB2 receptor dimer in a DMPC bilayer. | 2003 | J. Biomol. Struct. Dyn. | pmid:12956604 |
Beevers AJ and Kukol A | Conformational flexibility of the peptide hormone ghrelin in solution and lipid membrane bound: a molecular dynamics study. | 2006 | J. Biomol. Struct. Dyn. | pmid:16363872 |
Kothekar V | 260 ps molecular dynamics simulation of substance P with hydrated dimyristoyl phosphatidyl choline bilayer. | 1996 | J. Biomol. Struct. Dyn. | pmid:8906881 |
Yu K et al. | Interactions between mastoparan B and the membrane studied by 1H NMR spectroscopy. | 2001 | J. Biomol. Struct. Dyn. | pmid:11245254 |
Roy D and Mukhopadhyay C | GD1a in phospholipid bilayer: a molecular dynamics simulation. | 2001 | J. Biomol. Struct. Dyn. | pmid:11245258 |
Aller P et al. | Transmembrane helix packing of ErbB/Neu receptor in membrane environment: a molecular dynamics study. | 2006 | J. Biomol. Struct. Dyn. | pmid:17054379 |
Kothekar V et al. | Molecular dynamics simulation of conformational flexibility of alamethicin fragments in aqueous and membranous environment. | 1996 | J. Biomol. Struct. Dyn. | pmid:9016408 |
Chandrasekhar I and Gaber BP | Stabilization of the bio-membrane by small molecules: interaction of trehalose with the phospholipid bilayer. | 1988 | J. Biomol. Struct. Dyn. | pmid:3271505 |
Samna Soumana O et al. | Transmembrane peptides from tyrosine kinase receptor. Mutation-related behavior in a lipid bilayer investigated by molecular dynamics simulations. | 2005 | J. Biomol. Struct. Dyn. | pmid:15918680 |
Wong TC and Kamath S | Molecular dynamics simulations of adrenocorticotropin (1-24) peptide in a solvated dodecylphosphocholine (DPC) micelle and in a dimyistoylphosphatidylcholine (DMPC) bilayer. | 2002 | J. Biomol. Struct. Dyn. | pmid:12144351 |
Morita S et al. | Effect of saturation in phospholipid/fatty acid monolayers on interaction with amyloid β peptide. | 2018 | J. Biosci. Bioeng. | pmid:29175122 |
Brechling A et al. | Structural organization of DMPC lipid layers on chemically micropatterned self-assembled monolayers as biomimetic systems. | 2004 | J. Biotechnol. | pmid:15288947 |
Weitz M et al. | Quantitative composition and characterization of the proteins in membrane vesicles released from erythrocytes by dimyristoylphosphatidylcholine. A membrane system without cytoskeleton. | 1982 | J. Cell. Biochem. | pmid:6184380 |
Azzam DJ et al. | High-performance liquid chromatography method for quantifying sphingomyelin in rat brain. | 2007 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:17901003 |
Matt U et al. | WAVE1 mediates suppression of phagocytosis by phospholipid-derived DAMPs. | 2013 | J. Clin. Invest. | pmid:23934128 |
Suzuki M et al. | Targeting ceramide synthase 6-dependent metastasis-prone phenotype in lung cancer cells. | 2016 | J. Clin. Invest. | pmid:26650179 |
Concha MI et al. | Undetectable apolipoprotein A-I gene expression suggests an unusual mechanism of dietary lipid mobilisation in the intestine of Cyprinus carpio. | 2005 | J. Exp. Biol. | pmid:15781899 |
Wang Q et al. | In-vivo assessment of a novel polymer (SIBS) trileaflet heart valve. | 2010 | J. Heart Valve Dis. | pmid:20845899 |
Yamamoto KI | Proteolysis of the C5b-7 complex: cleavage of the C5b and C6 subunits and its effect on the interaction of the complex with phospholipid bilayers. | 1980 | J. Immunol. | pmid:6997387 |
Mold C and Gewurz H | Inhibitory effect of C-reactive protein on alternative C pathway activation by liposomes and Streptococcus pneumoniae. | 1981 | J. Immunol. | pmid:6913608 |
Whitten MM et al. | A novel role for an insect apolipoprotein (apolipophorin III) in beta-1,3-glucan pattern recognition and cellular encapsulation reactions. | 2004 | J. Immunol. | pmid:14764684 |
Podack ER et al. | Membrane attach complex of complement (MAC): three-dimensional analysis of MAC-phospholipid vesicle recombinants. | 1982 | J. Immunol. | pmid:6174630 |
Strejan GH et al. | Naturally occurring antibodies to liposomes. II. Specificity and electrophoretic pattern of rabbit antibodies reacting with sphingomyelin-containing liposomes. | 1981 | J. Immunol. | pmid:6787120 |
Ho RJ and Huang L | Interactions of antigen-sensitized liposomes with immobilized antibody: a homogeneous solid-phase immunoliposome assay. | 1985 | J. Immunol. | pmid:3886794 |
Mold C et al. | Interaction of C-reactive protein with liposomes. III. Membrane requirements for binding. | 1981 | J. Immunol. | pmid:7462634 |
Lopez-Berestein G et al. | Treatment and prophylaxis of disseminated infection due to Candida albicans in mice with liposome-encapsulated amphotericin B. | 1983 | J. Infect. Dis. | pmid:6842027 |
Pezeshk A et al. | Partitional and motional properties of a spin-labeled daunomycin in lipid bilayers. An ESR study. | 1992 | J. Inorg. Biochem. | pmid:1326024 |
Suwalsky M et al. | Structural effects of Zn(2+) on cell membranes and molecular models. | 2009 | J. Inorg. Biochem. | pmid:19327840 |
al-Baker S et al. | Synthesis and biological studies of new lipid-soluble cisplatin analogues entrapped in liposomes. | 1992 | J. Inorg. Biochem. | pmid:1431876 |
Suwalsky M et al. | Mn2+ exerts stronger structural effects than the Mn-citrate complex on the human erythrocyte membrane and molecular models. | 2010 | J. Inorg. Biochem. | pmid:19880186 |
Pezeshk A et al. | Orientational and motional properties of copper (II) complexes of dibenzotetraaza [14]annulenes in lipid bilayers: an ESR study. | 1991 | J. Inorg. Biochem. | pmid:1665172 |
Suwalsky M et al. | Interactions of Al(acac)3 with cell membranes and model phospholipid bilayers. | 1999 | J. Inorg. Biochem. | pmid:10499289 |
Subczynski WK et al. | Effects of probucol on phase transition and fluidity of phosphatidylcholine membranes: a spin label study. | 1994 | J. Inorg. Biochem. | pmid:8046434 |
Suwalsky M et al. | HgCl2 disrupts the structure of the human erythrocyte membrane and model phospholipid bilayers. | 2000 | J. Inorg. Biochem. | pmid:11065190 |
Suwalsky M et al. | Structural effects of titanium citrate on the human erythrocyte membrane. | 2005 | J. Inorg. Biochem. | pmid:15708797 |
Butikofer P et al. | Erythrocyte phospholipid organization and vesiculation in hereditary high red cell membrane phosphatidylcholine hemolytic anemia. | 1989 | J. Lab. Clin. Med. | pmid:2926237 |
Harbison GS and Griffin RG | Improved method for the synthesis of phosphatidylcholines. | 1984 | J. Lipid Res. | pmid:6512420 |
Zhu X et al. | Cysteine mutants of human apolipoprotein A-I: a study of secondary structural and functional properties. | 2005 | J. Lipid Res. | pmid:15805548 |
Fournier N et al. | Role of HDL phospholipid in efflux of cell cholesterol to whole serum: studies with human apoA-I transgenic rats. | 1996 | J. Lipid Res. | pmid:8864954 |
Manabe M et al. | New substrate for determination of serum lecithin:cholesterol acyltransferase. | 1987 | J. Lipid Res. | pmid:3681145 |