18194-24-6

18194-24-6 is a lipid of Glycerophospholipids (GP) class. 18194-24-6 is associated with abnormalities such as Cerebrovascular accident, Renal tubular disorder, Atherosclerosis, Hyperlipoproteinemia Type III and Lipid Metabolism Disorders. The involved functions are known as Process, protein folding, Catalyst, Biochemical Pathway and Fold in Medical Device Material. 18194-24-6 often locates in Tissue membrane, Membrane, periplasm, vesicle membrane and outer membrane. The associated genes with 18194-24-6 are Integral Membrane Proteins, Protein Structure, RTN4 gene, RTN4R gene and Protein, Organized by Structure. The related lipids are Micelles, dimyristoylphosphatidylglycerol, 1,2-dihexadecyl-sn-glycero-3-phosphocholine, Unilamellar Vesicles and cholesteryl oleate. The related experimental models are Mouse Model, Arthritis, Adjuvant-Induced, Disease model and Xenograft Model.

Cross Reference

Introduction

To understand associated biological information of 18194-24-6, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 18194-24-6?

18194-24-6 is suspected in Atherosclerosis, Cardiovascular Diseases, Dehydration, Abnormal shape, Renal tubular disorder, Hyperlipoproteinemia Type III and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 18194-24-6

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Adenocarcinoma D000230 166 associated lipids
Lung Neoplasms D008175 171 associated lipids
Body Weight D001835 333 associated lipids
Carcinoma D002277 18 associated lipids
Osteosarcoma D012516 50 associated lipids
Lymphoma, Large B-Cell, Diffuse D016403 13 associated lipids
Chemical and Drug Induced Liver Injury D056486 39 associated lipids
Alzheimer Disease D000544 76 associated lipids
Arteriosclerosis D001161 86 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with 18194-24-6

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 18194-24-6?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with 18194-24-6?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 18194-24-6?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with 18194-24-6?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 18194-24-6?

Mouse Model

Mouse Model are used in the study 'Association of a model class A (apolipoprotein) amphipathic alpha helical peptide with lipid: high resolution NMR studies of peptide.lipid discoidal complexes.' (Mishra VK et al., 2006).

Arthritis, Adjuvant-Induced

Arthritis, Adjuvant-Induced are used in the study 'T cell antigen receptor peptide-lipid membrane interactions using surface plasmon resonance.' (Bender V et al., 2004).

Disease model

Disease model are used in the study 'Kupffer cells do not play a role in governing the efficacy of liposomal mitoxantrone used to treat a tumor model designed to assess drug delivery to liver.' (Lim HJ et al., 2000).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with 18194-24-6

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Authors Title Published Journal PubMed Link
Curnow P and Booth PJ Combined kinetic and thermodynamic analysis of alpha-helical membrane protein unfolding. 2007 Proc. Natl. Acad. Sci. U.S.A. pmid:18025476
Surrey T and Jähnig F Refolding and oriented insertion of a membrane protein into a lipid bilayer. 1992 Proc. Natl. Acad. Sci. U.S.A. pmid:1502158
Tang P and Xu Y Large-scale molecular dynamics simulations of general anesthetic effects on the ion channel in the fully hydrated membrane: the implication of molecular mechanisms of general anesthesia. 2002 Proc. Natl. Acad. Sci. U.S.A. pmid:12438684
Pownall HJ et al. Activation of lecithin:cholesterol acyltransferase by a synthetic model lipid-associating peptide. 1980 Proc. Natl. Acad. Sci. U.S.A. pmid:6774331
Villinger S et al. Functional dynamics in the voltage-dependent anion channel. 2010 Proc. Natl. Acad. Sci. U.S.A. pmid:21148773
Dornmair K and Jähnig F Internal dynamics of lactose permease. 1989 Proc. Natl. Acad. Sci. U.S.A. pmid:2690075
Abbott GW et al. Interaction between soluble and membrane-embedded potassium channel peptides monitored by Fourier transform infrared spectroscopy. 2012 PLoS ONE pmid:23145073
Jo S et al. Automated builder and database of protein/membrane complexes for molecular dynamics simulations. 2007 PLoS ONE pmid:17849009
Bertelsen K et al. Mechanisms of peptide-induced pore formation in lipid bilayers investigated by oriented 31P solid-state NMR spectroscopy. 2012 PLoS ONE pmid:23094079
Vilches S et al. Neurotoxicity of prion peptides mimicking the central domain of the cellular prion protein. 2013 PLoS ONE pmid:23940658
Shrivastava S and Schneider MF Opto-mechanical coupling in interfaces under static and propagative conditions and its biological implications. 2013 PLoS ONE pmid:23861769
Lek MT et al. Swapping the N- and C-terminal domains of human apolipoprotein E3 and AI reveals insights into their structure/activity relationship. 2017 PLoS ONE pmid:28644829
Pavlidou M et al. Nanodiscs allow phage display selection for ligands to non-linear epitopes on membrane proteins. 2013 PLoS ONE pmid:24039747
Sontag TJ and Reardon CA Polymorphisms of mouse apolipoprotein A-II alter its physical and functional nature. 2014 PLoS ONE pmid:24520415
Fischer NO et al. Evaluation of nanolipoprotein particles (NLPs) as an in vivo delivery platform. 2014 PLoS ONE pmid:24675794
Sankhala RS et al. Correlation of membrane binding and hydrophobicity to the chaperone-like activity of PDC-109, the major protein of bovine seminal plasma. 2011 PLoS ONE pmid:21408153
Barrett MA et al. Interaction of aspirin (acetylsalicylic acid) with lipid membranes. 2012 PLoS ONE pmid:22529913
Anbazhagan V et al. Isothermal titration calorimetric studies on the interaction of the major bovine seminal plasma protein, PDC-109 with phospholipid membranes. 2011 PLoS ONE pmid:22022488
Wallgren M et al. Reconstitution of the anti-apoptotic Bcl-2 protein into lipid membranes and biophysical evidence for its detergent-driven association with the pro-apoptotic Bax protein. 2013 PLoS ONE pmid:23626686
Boffi F et al. MRS study of the interaction of dihydropyridines with lipid molecules in phosphatidylcholine vesicles. 2003 Physiol Chem Phys Med NMR pmid:15139283