1,2-Dioleoyl-sn-Glycero-3-Phosphocholine is a lipid of Glycerophospholipids (GP) class. 1,2-dioleoyl-sn-glycero-3-phosphocholine is associated with abnormalities such as Exanthema, Renal tubular disorder, Nodule, Gigantism and Mycoses. The involved functions are known as Lysis, Encapsulation, Process, Uptake and Flow or discharge. 1,2-dioleoyl-sn-glycero-3-phosphocholine often locates in Cytoplasmic matrix, Endosomes, soluble, Endoplasmic Reticulum and Membrane. The associated genes with 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine are P4HTM gene, synthetic peptide, BCAR1 gene, PCNA gene and CNTNAP1 gene. The related lipids are Liposomes, 1,2-oleoylphosphatidylcholine, 1,2-distearoylphosphatidylethanolamine, Butanols and Cardiolipins. The related experimental models are Mouse Model and Xenograft Model.
To understand associated biological information of 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
1,2-Dioleoyl-sn-Glycero-3-Phosphocholine is suspected in Gigantism, Nodule, protrusion, DERMATITIS HERPETIFORMIS, FAMILIAL, Exanthema, Renal tubular disorder and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Ovarian Neoplasms | D010051 | 10 associated lipids |
| Respiratory Syncytial Virus Infections | D018357 | 10 associated lipids |
| Celiac Disease | D002446 | 16 associated lipids |
| Niemann-Pick Diseases | D009542 | 25 associated lipids |
| Neuroblastoma | D009447 | 66 associated lipids |
| Atherosclerosis | D050197 | 85 associated lipids |
| Hemolysis | D006461 | 131 associated lipids |
| Edema | D004487 | 152 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
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| Lipid concept | Cross reference | Weighted score | Related literatures |
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| Gene | Cross reference | Weighted score | Related literatures |
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Xenograft Model are used in the study 'Therapeutic targeting of PELP1 prevents ovarian cancer growth and metastasis.' (Chakravarty D et al., 2011).
Mouse Model are used in the study 'Therapeutic EphA2 gene targeting in vivo using neutral liposomal small interfering RNA delivery.' (Landen CN et al., 2005).
| Model | Cross reference | Weighted score | Related literatures |
|---|
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Mukherjee S et al. | Membrane localization and dynamics of Nile Red: effect of cholesterol. | 2007 | Biochim. Biophys. Acta | pmid:16934217 |
| Raghuraman H and Chattopadhyay A | Orientation and dynamics of melittin in membranes of varying composition utilizing NBD fluorescence. | 2007 | Biophys. J. | pmid:17114219 |
| Nazarov PV et al. | FRET study of membrane proteins: determination of the tilt and orientation of the N-terminal domain of M13 major coat protein. | 2007 | Biophys. J. | pmid:17114224 |
| Coll EP et al. | The distribution and conformation of very long-chain plant wax components in a lipid bilayer. | 2007 | J Phys Chem B | pmid:17608528 |
| Morandat S and El Kirat K | Solubilization of supported lipid membranes by octyl glucoside observed by time-lapse atomic force microscopy. | 2007 | Colloids Surf B Biointerfaces | pmid:17207975 |
| Inaoka Y and Yamazaki M | Vesicle fission of giant unilamellar vesicles of liquid-ordered-phase membranes induced by amphiphiles with a single long hydrocarbon chain. | 2007 | Langmuir | pmid:17209626 |
| Morandat S and El Kirat K | Real-time atomic force microscopy reveals cytochrome c-induced alterations in neutral lipid bilayers. | 2007 | Langmuir | pmid:17887784 |
| Kucerka N et al. | Curvature effect on the structure of phospholipid bilayers. | 2007 | Langmuir | pmid:17241048 |
| Ishitsuka R and Kobayashi T | Cholesterol and lipid/protein ratio control the oligomerization of a sphingomyelin-specific toxin, lysenin. | 2007 | Biochemistry | pmid:17243772 |
| Huang SC et al. | Formation, stability, and mobility of one-dimensional lipid bilayers on polysilicon nanowires. | 2007 | Nano Lett. | pmid:17900161 |
| Chen L et al. | The partition of cholesterol between ordered and fluid bilayers of phosphatidylcholine: a synchrotron X-ray diffraction study. | 2007 | Biochim. Biophys. Acta | pmid:17900525 |
| Pabst G et al. | Entropy-driven softening of fluid lipid bilayers by alamethicin. | 2007 | Langmuir | pmid:17939689 |
| Lapinski MM et al. | Comparison of liposomes formed by sonication and extrusion: rotational and translational diffusion of an embedded chromophore. | 2007 | Langmuir | pmid:17939695 |
| Arnusch CJ et al. | Enhanced membrane pore formation by multimeric/oligomeric antimicrobial peptides. | 2007 | Biochemistry | pmid:17944489 |
| Veatch SL et al. | Critical fluctuations in domain-forming lipid mixtures. | 2007 | Proc. Natl. Acad. Sci. U.S.A. | pmid:17962417 |
| Lenhert S et al. | Massively parallel dip-pen nanolithography of heterogeneous supported phospholipid multilayer patterns. | 2007 | Small | pmid:17294472 |
| Hathcock J et al. | Lipid-bound factor Xa regulates tissue factor activity. | 2007 | Biochemistry | pmid:17469850 |
| de Almeida RF et al. | Complexity of lipid domains and rafts in giant unilamellar vesicles revealed by combining imaging and microscopic and macroscopic time-resolved fluorescence. | 2007 | Biophys. J. | pmid:17449668 |
| Coban O et al. | Ganglioside partitioning and aggregation in phase-separated monolayers characterized by bodipy GM1 monomer/dimer emission. | 2007 | Langmuir | pmid:17477552 |
| Yang L et al. | Synthetic antimicrobial oligomers induce a composition-dependent topological transition in membranes. | 2007 | J. Am. Chem. Soc. | pmid:17880067 |
| Mogensen JE et al. | The major allergen from birch tree pollen, Bet v 1, binds and permeabilizes membranes. | 2007 | Biochemistry | pmid:17311414 |
| Zakharov SD et al. | Helical alpha-synuclein forms highly conductive ion channels. | 2007 | Biochemistry | pmid:18031063 |
| Stengel G et al. | DNA-induced programmable fusion of phospholipid vesicles. | 2007 | J. Am. Chem. Soc. | pmid:17629277 |
| Tian A et al. | Line tension at fluid membrane domain boundaries measured by micropipette aspiration. | 2007 | Phys. Rev. Lett. | pmid:17677743 |
| Hac-Wydro K et al. | The influence of phospholipid structure on the interactions with nystatin, a polyene antifungal antibiotic A Langmuir monolayer study. | 2007 | Chem. Phys. Lipids | pmid:17681287 |
| Quemeneur F et al. | Large and giant vesicles "decorated" with chitosan: effects of pH, salt or glucose stress, and surface adhesion. | 2007 | Biomacromolecules | pmid:17658883 |
| Giocondi MC et al. | Remodeling of ordered membrane domains by GPI-anchored intestinal alkaline phosphatase. | 2007 | Langmuir | pmid:17661499 |
| Hendrich AB et al. | Phase separation is induced by phenothiazine derivatives in phospholipid/sphingomyelin/cholesterol mixtures containing low levels of cholesterol and sphingomyelin. | 2007 | Biophys. Chem. | pmid:17662517 |
| Trépout S et al. | Organization of reconstituted lipoprotein MexA onto supported lipid membrane. | 2007 | Eur. Biophys. J. | pmid:17665187 |
| Hughes E et al. | Solid-state NMR and functional measurements indicate that the conserved tyrosine residues of sarcolipin are involved directly in the inhibition of SERCA1. | 2007 | J. Biol. Chem. | pmid:17616528 |
| Ghalit N et al. | Synthesis of bicyclic alkene-/alkane-bridged nisin mimics by ring-closing metathesis and their biochemical evaluation as lipid II binders: toward the design of potential novel antibiotics. | 2007 | Chembiochem | pmid:17674393 |
| Esposito C et al. | Flicker spectroscopy of thermal lipid bilayer domain boundary fluctuations. | 2007 | Biophys. J. | pmid:17644560 |
| Salamon Z et al. | Plasmon-waveguide resonance spectroscopy studies of lateral segregation in solid-supported proteolipid bilayers. | 2007 | Methods Mol. Biol. | pmid:18214380 |
| McIntosh TJ | X-ray diffraction to determine the thickness of raft and nonraft bilayers. | 2007 | Methods Mol. Biol. | pmid:18214383 |
| Pencer J et al. | Small-angle neutron scattering to detect rafts and lipid domains. | 2007 | Methods Mol. Biol. | pmid:18214384 |
| Burns AR | Atomic force microscopy of lipid domains in supported model membranes. | 2007 | Methods Mol. Biol. | pmid:18214386 |
| Lee JY and Schick M | Dependence of the energies of fusion on the intermembrane separation: optimal and constrained. | 2007 | J Chem Phys | pmid:17718633 |
| Salvati A et al. | Small angle scattering and zeta potential of liposomes loaded with octa(carboranyl)porphyrazine. | 2007 | J Phys Chem B | pmid:17696389 |
| Erbe A and Sigel R | Tilt angle of lipid acyl chains in unilamellar vesicles determined by ellipsometric light scattering. | 2007 | Eur Phys J E Soft Matter | pmid:17431539 |
| Traaseth NJ et al. | Spectroscopic validation of the pentameric structure of phospholamban. | 2007 | Proc. Natl. Acad. Sci. U.S.A. | pmid:17804809 |
| Karlovská J et al. | Effect of amphiphilic surfactant LDAO on the solubilization of DOPC vesicles and on the activity of Ca(2+)-ATPase reconstituted in DOPC vesicles. | 2007 | Gen. Physiol. Biophys. | pmid:18281747 |
| Brown AC et al. | Measuring raft size as a function of membrane composition in PC-based systems: Part 1--binary systems. | 2007 | Langmuir | pmid:17887778 |
| Brown AC et al. | Measuring raft size as a function of membrane composition in PC-based systems: Part II--ternary systems. | 2007 | Langmuir | pmid:17887779 |
| Buboltz JT et al. | High-resolution mapping of phase behavior in a ternary lipid mixture: do lipid-raft phase boundaries depend on the sample preparation procedure? | 2007 | Langmuir | pmid:17949025 |
| Blanchette CD et al. | Using nucleation rates to determine the interfacial line tension of symmetric and asymmetric lipid bilayer domains. | 2007 | Langmuir | pmid:17451264 |
| Spurlin TA and Gewirth AA | Charge dependence of a nanoscale supercrystal phase in a supported lipid bilayer. | 2007 | J. Am. Chem. Soc. | pmid:17845046 |
| Anton N et al. | The influence of headgroup structure and fatty acyl chain saturation of phospholipids on monolayer behavior: a comparative rheological study. | 2007 | Chem. Phys. Lipids | pmid:17868664 |
| Leonenko Z et al. | Effect of cholesterol on the physical properties of pulmonary surfactant films: atomic force measurements study. | 2006 Jun-Jul | Ultramicroscopy | pmid:16675117 |
| Garcia MT et al. | Transdermal delivery of ketoprofen: the influence of drug-dioleylphosphatidylcholine interactions. | 2006 | Pharm. Res. | pmid:16858649 |
| Komura S et al. | Tension-induced morphological transition in mixed lipid bilayers. | 2006 | Langmuir | pmid:16863221 |
| Li L and Cheng JX | Coexisting stripe- and patch-shaped domains in giant unilamellar vesicles. | 2006 | Biochemistry | pmid:17002282 |
| Shaw JE et al. | Tracking peptide-membrane interactions: insights from in situ coupled confocal-atomic force microscopy imaging of NAP-22 peptide insertion and assembly. | 2006 | J. Struct. Biol. | pmid:16889981 |
| Dixit SS et al. | Glass bead probes of local structural and mechanical properties of fluid, supported membranes. | 2006 | Chemphyschem | pmid:16847842 |
| Massey JB and Pownall HJ | Structures of biologically active oxysterols determine their differential effects on phospholipid membranes. | 2006 | Biochemistry | pmid:16939227 |
| Chiantia S et al. | Effects of ceramide on liquid-ordered domains investigated by simultaneous AFM and FCS. | 2006 | Biophys. J. | pmid:16565041 |
| Vemparala S et al. | Partitioning of anesthetics into a lipid bilayer and their interaction with membrane-bound peptide bundles. | 2006 | Biophys. J. | pmid:16877515 |
| Chiantia S et al. | Combined AFM and two-focus SFCS study of raft-exhibiting model membranes. | 2006 | Chemphyschem | pmid:17051578 |
| Halder J et al. | Focal adhesion kinase targeting using in vivo short interfering RNA delivery in neutral liposomes for ovarian carcinoma therapy. | 2006 | Clin. Cancer Res. | pmid:16914580 |
| Benz RW et al. | Diffraction-based density restraints for membrane and membrane-peptide molecular dynamics simulations. | 2006 | Biophys. J. | pmid:16950837 |
| Buffy JJ et al. | Two-dimensional solid-state NMR reveals two topologies of sarcolipin in oriented lipid bilayers. | 2006 | Biochemistry | pmid:16953579 |
| Koynova R et al. | An intracellular lamellar-nonlamellar phase transition rationalizes the superior performance of some cationic lipid transfection agents. | 2006 | Proc. Natl. Acad. Sci. U.S.A. | pmid:16983097 |
| Castro-Román F et al. | Investigation of finite system-size effects in molecular dynamics simulations of lipid bilayers. | 2006 | J Phys Chem B | pmid:17125387 |
| Yamada A et al. | Spontaneous transfer of phospholipid-coated oil-in-oil and water-in-oil micro-droplets through an oil/water interface. | 2006 | Langmuir | pmid:17106968 |
| Nikolov V et al. | Bias-dependent admittance in hybrid bilayer membranes. | 2006 | Langmuir | pmid:16893210 |
| Macdonald RC et al. | Surface properties of dioleoyl-sn-glycerol-3-ethylphosphocholine, a cationic phosphatidylcholine transfection agent, alone and in combination with lipids or DNA. | 2006 | Langmuir | pmid:16519481 |
| Glassinger E and Raphael RM | Influence of thermally driven surface undulations on tethers formed from bilayer membranes. | 2006 | Biophys. J. | pmid:16648163 |
| Rossetti FF et al. | Asymmetric distribution of phosphatidyl serine in supported phospholipid bilayers on titanium dioxide. | 2006 | Langmuir | pmid:16584212 |
| Landen CN et al. | Intraperitoneal delivery of liposomal siRNA for therapy of advanced ovarian cancer. | 2006 | Cancer Biol. Ther. | pmid:17106249 |
| Richter RP et al. | Formation of solid-supported lipid bilayers: an integrated view. | 2006 | Langmuir | pmid:16584220 |
| Koçer A et al. | Rationally designed chemical modulators convert a bacterial channel protein into a pH-sensory valve. | 2006 | Angew. Chem. Int. Ed. Engl. | pmid:16586527 |
| de Jonge J et al. | Use of a dialyzable short-chain phospholipid for efficient solubilization and reconstitution of influenza virus envelopes. | 2006 | Biochim. Biophys. Acta | pmid:16630533 |
| Ewert KK et al. | A columnar phase of dendritic lipid-based cationic liposome-DNA complexes for gene delivery: hexagonally ordered cylindrical micelles embedded in a DNA honeycomb lattice. | 2006 | J. Am. Chem. Soc. | pmid:16551108 |
| Nazarov PV et al. | FRET study of membrane proteins: simulation-based fitting for analysis of membrane protein embedment and association. | 2006 | Biophys. J. | pmid:16632512 |
| Herbig ME et al. | The cell penetrating peptides pVEC and W2-pVEC induce transformation of gel phase domains in phospholipid bilayers without affecting their integrity. | 2006 | Biochemistry | pmid:16533042 |
| Holland GP et al. | Distinguishing individual lipid headgroup mobility and phase transitions in raft-forming lipid mixtures with 31P MAS NMR. | 2006 | Biophys. J. | pmid:16533851 |
| Caracciolo G et al. | One-dimensional thermotropic dilatation area of lipid headgroups within lamellar lipid/DNA complexes. | 2006 | Langmuir | pmid:16618174 |
| Micelli S et al. | Effect of pH-variation on insertion and ion channel formation of human calcitonin into planar lipid bilayers. | 2006 | Front. Biosci. | pmid:16720289 |
| Devanathan S et al. | Effects of sphingomyelin, cholesterol and zinc ions on the binding, insertion and aggregation of the amyloid Abeta(1-40) peptide in solid-supported lipid bilayers. | 2006 | FEBS J. | pmid:16689927 |
| Kahya N | Targeting membrane proteins to liquid-ordered phases: molecular self-organization explored by fluorescence correlation spectroscopy. | 2006 | Chem. Phys. Lipids | pmid:16696961 |
| Ringstad L et al. | Effect of peptide length on the interaction between consensus peptides and DOPC/DOPA bilayers. | 2006 | Langmuir | pmid:16700592 |
| Park JW and Lee GU | Properties of mixed lipid monolayers assembled on hydrophobic surfaces through vesicle adsorption. | 2006 | Langmuir | pmid:16700594 |
| Hayes ME et al. | Assembly of nucleic acid-lipid nanoparticles from aqueous-organic monophases. | 2006 | Biochim. Biophys. Acta | pmid:16678786 |
| Ganchev DN et al. | Size and orientation of the lipid II headgroup as revealed by AFM imaging. | 2006 | Biochemistry | pmid:16681392 |
| Pereira-Lachataignerais J et al. | Effect of sodium dodecyl sulfate at different hydration conditions on dioleoyl phosphatidylcholine bilayers studied by grazing incidence X-ray diffraction. | 2006 | Langmuir | pmid:16732649 |
| Lanoul A et al. | Imaging nanometer scale optical heterogeneities in phospholipid monolayers deposited on metal island films. | 2006 | J Nanosci Nanotechnol | pmid:16573070 |
| Taniguchi Y et al. | Rapid phase change of lipid microdomains in giant vesicles induced by conversion of sphingomyelin to ceramide. | 2006 | Biochim. Biophys. Acta | pmid:16580624 |
| Lindblom G et al. | Lipid lateral diffusion in bilayers with phosphatidylcholine, sphingomyelin and cholesterol. An NMR study of dynamics and lateral phase separation. | 2006 | Chem. Phys. Lipids | pmid:16580657 |
| Kleinschmidt JH | Folding kinetics of the outer membrane proteins OmpA and FomA into phospholipid bilayers. | 2006 | Chem. Phys. Lipids | pmid:16581049 |
| Torreggiani A et al. | Investigation of radical-based damage of RNase A in aqueous solution and lipid vesicles. | 2006 | Biopolymers | pmid:16177964 |
| Fa N et al. | Effect of the antibiotic azithromycin on thermotropic behavior of DOPC or DPPC bilayers. | 2006 | Chem. Phys. Lipids | pmid:17007828 |
| Bhide SY and Berkowitz ML | The behavior of reorientational correlation functions of water at the water-lipid bilayer interface. | 2006 | J Chem Phys | pmid:16965111 |
| O'Connell RJ et al. | Gating and conductance changes in BK(Ca) channels in bilayers are reciprocal. | 2006 | J. Membr. Biol. | pmid:17468961 |
| Nicolini C et al. | Pressure tuning of the morphology of heterogeneous lipid vesicles: a two-photon-excitation fluorescence microscopy study. | 2006 | Biophys. J. | pmid:16877511 |
| Mills PC et al. | Comparison of surfactant lipids between pleural and pulmonary lining fluids. | 2006 | Pulm Pharmacol Ther | pmid:16168690 |
| Pocanschi CL et al. | The major outer membrane protein of Fusobacterium nucleatum (FomA) folds and inserts into lipid bilayers via parallel folding pathways. | 2006 | J. Mol. Biol. | pmid:16310217 |
| Hochrein MB et al. | Structure and mobility of lipid membranes on a thermoplastic substrate. | 2006 | Langmuir | pmid:16401100 |
| Mancheño JM et al. | A complementary microscopy analysis of Sticholysin II crystals on lipid films: Atomic force and transmission electron characterizations. | 2006 | Biophys. Chem. | pmid:16225981 |
| Petrache HI et al. | Swelling of phospholipids by monovalent salt. | 2006 | J. Lipid Res. | pmid:16267342 |
| Karlovská J et al. | Influence of N-dodecyl-N,N-dimethylamine N-oxide on the activity of sarcoplasmic reticulum Ca(2+)-transporting ATPase reconstituted into diacylphosphatidylcholine vesicles: efects of bilayer physical parameters. | 2006 | Biophys. Chem. | pmid:16223561 |
| Feigenson GW | Phase behavior of lipid mixtures. | 2006 | Nat. Chem. Biol. | pmid:17051225 |