1,2-Dioleoyl-sn-Glycero-3-Phosphocholine is a lipid of Glycerophospholipids (GP) class. 1,2-dioleoyl-sn-glycero-3-phosphocholine is associated with abnormalities such as Exanthema, Renal tubular disorder, Nodule, Gigantism and Mycoses. The involved functions are known as Lysis, Encapsulation, Process, Uptake and Flow or discharge. 1,2-dioleoyl-sn-glycero-3-phosphocholine often locates in Cytoplasmic matrix, Endosomes, soluble, Endoplasmic Reticulum and Membrane. The associated genes with 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine are P4HTM gene, synthetic peptide, BCAR1 gene, PCNA gene and CNTNAP1 gene. The related lipids are Liposomes, 1,2-oleoylphosphatidylcholine, 1,2-distearoylphosphatidylethanolamine, Butanols and Cardiolipins. The related experimental models are Mouse Model and Xenograft Model.
To understand associated biological information of 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
1,2-Dioleoyl-sn-Glycero-3-Phosphocholine is suspected in Gigantism, Nodule, protrusion, DERMATITIS HERPETIFORMIS, FAMILIAL, Exanthema, Renal tubular disorder and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Respiratory Syncytial Virus Infections | D018357 | 10 associated lipids |
| Ovarian Neoplasms | D010051 | 10 associated lipids |
| Celiac Disease | D002446 | 16 associated lipids |
| Niemann-Pick Diseases | D009542 | 25 associated lipids |
| Neuroblastoma | D009447 | 66 associated lipids |
| Atherosclerosis | D050197 | 85 associated lipids |
| Hemolysis | D006461 | 131 associated lipids |
| Edema | D004487 | 152 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
| Gene | Cross reference | Weighted score | Related literatures |
|---|
Xenograft Model are used in the study 'Therapeutic targeting of PELP1 prevents ovarian cancer growth and metastasis.' (Chakravarty D et al., 2011).
Mouse Model are used in the study 'Therapeutic EphA2 gene targeting in vivo using neutral liposomal small interfering RNA delivery.' (Landen CN et al., 2005).
| Model | Cross reference | Weighted score | Related literatures |
|---|
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Darkes MJ and Bradshaw JP | Real-time swelling-series method improves the accuracy of lamellar neutron-diffraction data. | 2000 | Acta Crystallogr. D Biol. Crystallogr. | pmid:10666626 |
| Rudolphi-Skórska E et al. | Impact of polyphenol-rich green tea extracts on the protection of DOPC monolayer against damage caused by ozone induced lipid oxidation. | 2018 | Acta Biochim. Pol. | pmid:29850658 |
| Janas T et al. | The effect of undecaprenol on bilayer lipid membranes. | 1994 | Acta Biochim. Pol. | pmid:7856407 |
| Janas T et al. | The effect of hexadecaprenol on molecular organisation and transport properties of model membranes. | 2000 | Acta Biochim. Pol. | pmid:11310968 |
| Markiewicz M et al. | Properties of water hydrating the galactolipid and phospholipid bilayers: a molecular dynamics simulation study. | 2015 | Acta Biochim. Pol. | pmid:26291044 |
| Woźniak M et al. | Diversity of the effect of phosphatidylcholine and sphingomyelin on adenylate deaminase from pig brain. | 1987 | Acta Biochim. Pol. | pmid:3687300 |
| Tashiro K et al. | Modified natural and synthetically reconstituted surfactant therapies for acute lung injury caused by endotoxin in rats. | 1999 | Acta Anaesthesiol Scand | pmid:10492410 |
| Gordillo GJ et al. | Interactions of gold nanoparticles with a phospholipid monolayer membrane on mercury. | 2014 | ACS Nano | pmid:24878256 |
| Perrault SD and Shih WM | Virus-inspired membrane encapsulation of DNA nanostructures to achieve in vivo stability. | 2014 | ACS Nano | pmid:24694301 |
| Andrecka J et al. | Direct observation and control of supported lipid bilayer formation with interferometric scattering microscopy. | 2013 | ACS Nano | pmid:24251388 |