1,2-Dioleoyl-sn-Glycero-3-Phosphocholine

1,2-Dioleoyl-sn-Glycero-3-Phosphocholine is a lipid of Glycerophospholipids (GP) class. 1,2-dioleoyl-sn-glycero-3-phosphocholine is associated with abnormalities such as Exanthema, Renal tubular disorder, Nodule, Gigantism and Mycoses. The involved functions are known as Lysis, Encapsulation, Process, Uptake and Flow or discharge. 1,2-dioleoyl-sn-glycero-3-phosphocholine often locates in Cytoplasmic matrix, Endosomes, soluble, Endoplasmic Reticulum and Membrane. The associated genes with 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine are P4HTM gene, synthetic peptide, BCAR1 gene, PCNA gene and CNTNAP1 gene. The related lipids are Liposomes, 1,2-oleoylphosphatidylcholine, 1,2-distearoylphosphatidylethanolamine, Butanols and Cardiolipins. The related experimental models are Mouse Model and Xenograft Model.

Cross Reference

Introduction

To understand associated biological information of 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine?

1,2-Dioleoyl-sn-Glycero-3-Phosphocholine is suspected in Gigantism, Nodule, protrusion, DERMATITIS HERPETIFORMIS, FAMILIAL, Exanthema, Renal tubular disorder and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine

MeSH term MeSH ID Detail
Respiratory Syncytial Virus Infections D018357 10 associated lipids
Ovarian Neoplasms D010051 10 associated lipids
Celiac Disease D002446 16 associated lipids
Niemann-Pick Diseases D009542 25 associated lipids
Neuroblastoma D009447 66 associated lipids
Atherosclerosis D050197 85 associated lipids
Hemolysis D006461 131 associated lipids
Edema D004487 152 associated lipids
Total 8

PubChem Associated disorders and diseases

What pathways are associated with 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine?

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What functions are associated with 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine?

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What genes are associated with 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine?

Xenograft Model

Xenograft Model are used in the study 'Therapeutic targeting of PELP1 prevents ovarian cancer growth and metastasis.' (Chakravarty D et al., 2011).

Mouse Model

Mouse Model are used in the study 'Therapeutic EphA2 gene targeting in vivo using neutral liposomal small interfering RNA delivery.' (Landen CN et al., 2005).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine

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Authors Title Published Journal PubMed Link
Leventis R et al. Divalent cation induced fusion and lipid lateral segregation in phosphatidylcholine-phosphatidic acid vesicles. 1986 Biochemistry pmid:3801406
Niu SL et al. Trans fatty acid derived phospholipids show increased membrane cholesterol and reduced receptor activation as compared to their cis analogs. 2005 Biochemistry pmid:15766276
Lee J and Lentz BR Outer leaflet-packing defects promote poly(ethylene glycol)-mediated fusion of large unilamellar vesicles. 1997 Biochemistry pmid:9003195
Tatulian SA et al. Uncovering a calcium-regulated membrane-binding mechanism for soybean lipoxygenase-1. 1998 Biochemistry pmid:9799511
Buffy JJ et al. Two-dimensional solid-state NMR reveals two topologies of sarcolipin in oriented lipid bilayers. 2006 Biochemistry pmid:16953579
Curran AR et al. Modulation of folding and assembly of the membrane protein bacteriorhodopsin by intermolecular forces within the lipid bilayer. 1999 Biochemistry pmid:10413507
Wilschut J et al. Kinetics of Ca2+-induced fusion of cardiolipin-phosphatidylcholine vesicles: correlation between vesicle aggregation, bilayer destabilization, and fusion. 1985 Biochemistry pmid:4063345
Kubo M and Hostetler KY Mechanism of cationic amphiphilic drug inhibition of purified lysosomal phospholipase A1. 1985 Biochemistry pmid:4084534
Caputo GA and London E Position and ionization state of Asp in the core of membrane-inserted alpha helices control both the equilibrium between transmembrane and nontransmembrane helix topography and transmembrane helix positioning. 2004 Biochemistry pmid:15236588
Keller RC et al. Anionic phospholipids are essential for alpha-helix formation of the signal peptide of prePhoE upon interaction with phospholipid vesicles. 1992 Biochemistry pmid:1310616
BaÅŸaran N et al. Effect of lipid unsaturation on the binding of native and a mutant form of cytochrome b5 to membranes. 1999 Biochemistry pmid:10563808
Ganchev DN et al. Size and orientation of the lipid II headgroup as revealed by AFM imaging. 2006 Biochemistry pmid:16681392
Abe M et al. Molecular mechanisms for the induction of peroxidase activity of the cytochrome c-cardiolipin complex. 2011 Biochemistry pmid:21877718
Miller CR et al. Liposome-cell interactions in vitro: effect of liposome surface charge on the binding and endocytosis of conventional and sterically stabilized liposomes. 1998 Biochemistry pmid:9737866
Wu F et al. Stability of annexin V in ternary complexes with Ca2+ and anionic phospholipids: IR studies of monolayer and bulk phases. 1999 Biochemistry pmid:9888820
Liu F and Chong PL Evidence for a regulatory role of cholesterol superlattices in the hydrolytic activity of secretory phospholipase A2 in lipid membranes. 1999 Biochemistry pmid:10194297
Gomez B and Robinson NC Phospholipase digestion of bound cardiolipin reversibly inactivates bovine cytochrome bc1. 1999 Biochemistry pmid:10413476
Ostroski M et al. Analysis of a novel diacylglycerol kinase from Dictyostelium discoideum: DGKA. 2005 Biochemistry pmid:16042397
Ramalingam TS et al. Ricin-membrane interaction: membrane penetration depth by fluorescence quenching and resonance energy transfer. 1994 Biochemistry pmid:7918445
Bavdek A et al. Sterol and pH interdependence in the binding, oligomerization, and pore formation of Listeriolysin O. 2007 Biochemistry pmid:17358050
Antollini SS and Barrantes FJ Disclosure of discrete sites for phospholipid and sterols at the protein-lipid interface in native acetylcholine receptor-rich membrane. 1998 Biochemistry pmid:9843433
Xu X and London E The effect of sterol structure on membrane lipid domains reveals how cholesterol can induce lipid domain formation. 2000 Biochemistry pmid:10653627
Abrams FS and London E Extension of the parallax analysis of membrane penetration depth to the polar region of model membranes: use of fluorescence quenching by a spin-label attached to the phospholipid polar headgroup. 1993 Biochemistry pmid:8399232
Kapralov AA et al. The hierarchy of structural transitions induced in cytochrome c by anionic phospholipids determines its peroxidase activation and selective peroxidation during apoptosis in cells. 2007 Biochemistry pmid:18004876
Käsbauer M and Bayerl TM Formation of domains of cationic or anionic lipids in binary lipid mixtures increases the electrostatic coupling strength of water-soluble proteins to supported bilayers. 1999 Biochemistry pmid:10563810
Sitaram N and Nagaraj R Interaction of the 47-residue antibacterial peptide seminalplasmin and its 13-residue fragment which has antibacterial and hemolytic activities with model membranes. 1993 Biochemistry pmid:8457573
Pécheur EI et al. Lipid headgroup spacing and peptide penetration, but not peptide oligomerization, modulate peptide-induced fusion. 1999 Biochemistry pmid:9890918
Wang T et al. Nanomechanical recognition of sphingomyelin-rich membrane domains by atomic force microscopy. 2012 Biochemistry pmid:22148674
Kaetzel MA et al. Phosphorylation mutants elucidate the mechanism of annexin IV-mediated membrane aggregation. 2001 Biochemistry pmid:11300800
Meijer AB et al. Configurations of the N-terminal amphipathic domain of the membrane-bound M13 major coat protein. 2001 Biochemistry pmid:11305925
Srivastava A et al. Soluble phosphatidylserine binds to a single identified site in the C2 domain of human factor Va. 2001 Biochemistry pmid:11444970
Chattopadhyay A and Mukherjee S Fluorophore environments in membrane-bound probes: a red edge excitation shift study. 1993 Biochemistry pmid:8466919
Chen SY et al. Quantitation of lateral stress in lipid layer containing nonbilayer phase preferring lipids by frequency-domain fluorescence spectroscopy. 1992 Biochemistry pmid:1567830
Tournois H et al. Gramicidin A induced fusion of large unilamellar dioleoylphosphatidylcholine vesicles and its relation to the induction of type II nonbilayer structures. 1990 Biochemistry pmid:1701325
Massey JB and Pownall HJ The polar nature of 7-ketocholesterol determines its location within membrane domains and the kinetics of membrane microsolubilization by apolipoprotein A-I. 2005 Biochemistry pmid:16042420
Patel GJ et al. The periplasmic chaperone Skp facilitates targeting, insertion, and folding of OmpA into lipid membranes with a negative membrane surface potential. 2009 Biochemistry pmid:19780589
Rand RP et al. Membrane curvature, lipid segregation, and structural transitions for phospholipids under dual-solvent stress. 1990 Biochemistry pmid:2322550
Hayashibara M and London E Topography of diphtheria toxin A chain inserted into lipid vesicles. 2005 Biochemistry pmid:15697244
Yang L et al. New phases of phospholipids and implications to the membrane fusion problem. 2003 Biochemistry pmid:12779317
Muller JM et al. Effect of gramicidin A on structure and dynamics of lipid vesicle bilayers. A time-resolved fluorescence depolarization study. 1995 Biochemistry pmid:7534479
Clark EH et al. The role of tryptophan residues in an integral membrane protein: diacylglycerol kinase. 2003 Biochemistry pmid:12974643
Mukherjee S and Chattopadhyay A Motionally restricted tryptophan environments at the peptide-lipid interface of gramicidin channels. 1994 Biochemistry pmid:7513554
Tate MW and Gruner SM Temperature dependence of the structural dimensions of the inverted hexagonal (HII) phase of phosphatidylethanolamine-containing membranes. 1989 Biochemistry pmid:2765485
Wright CS et al. Crystal structure analysis of phosphatidylcholine-GM2-activator product complexes: evidence for hydrolase activity. 2005 Biochemistry pmid:16216074
Koshy SS et al. Hydrogen exchange differences between chemoreceptor signaling complexes localize to functionally important subdomains. 2014 Biochemistry pmid:25420045
Moniruzzaman M et al. Entry of a Six-Residue Antimicrobial Peptide Derived from Lactoferricin B into Single Vesicles and Escherichia coli Cells without Damaging their Membranes. 2017 Biochemistry pmid:28752991
Meijer AB et al. Membrane assembly of the bacteriophage Pf3 major coat protein. 2000 Biochemistry pmid:10821689
Hathcock JJ et al. Phospholipid regulates the activation of factor X by tissue factor/factor VIIa (TF/VIIa) via substrate and product interactions. 2005 Biochemistry pmid:15924438
Ellens H et al. Fusion of phosphatidylethanolamine-containing liposomes and mechanism of the L alpha-HII phase transition. 1986 Biochemistry pmid:3741846
Lindhout T et al. Thrombin generation and inactivation in the presence of antithrombin III and heparin. 1986 Biochemistry pmid:3790498