1,2-Dioleoyl-sn-Glycero-3-Phosphocholine is a lipid of Glycerophospholipids (GP) class. 1,2-dioleoyl-sn-glycero-3-phosphocholine is associated with abnormalities such as Exanthema, Renal tubular disorder, Nodule, Gigantism and Mycoses. The involved functions are known as Lysis, Encapsulation, Process, Uptake and Flow or discharge. 1,2-dioleoyl-sn-glycero-3-phosphocholine often locates in Cytoplasmic matrix, Endosomes, soluble, Endoplasmic Reticulum and Membrane. The associated genes with 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine are P4HTM gene, synthetic peptide, BCAR1 gene, PCNA gene and CNTNAP1 gene. The related lipids are Liposomes, 1,2-oleoylphosphatidylcholine, 1,2-distearoylphosphatidylethanolamine, Butanols and Cardiolipins. The related experimental models are Mouse Model and Xenograft Model.
To understand associated biological information of 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
1,2-Dioleoyl-sn-Glycero-3-Phosphocholine is suspected in Gigantism, Nodule, protrusion, DERMATITIS HERPETIFORMIS, FAMILIAL, Exanthema, Renal tubular disorder and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Respiratory Syncytial Virus Infections | D018357 | 10 associated lipids |
| Ovarian Neoplasms | D010051 | 10 associated lipids |
| Celiac Disease | D002446 | 16 associated lipids |
| Niemann-Pick Diseases | D009542 | 25 associated lipids |
| Neuroblastoma | D009447 | 66 associated lipids |
| Atherosclerosis | D050197 | 85 associated lipids |
| Hemolysis | D006461 | 131 associated lipids |
| Edema | D004487 | 152 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
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| Function | Cross reference | Weighted score | Related literatures |
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| Lipid concept | Cross reference | Weighted score | Related literatures |
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| Gene | Cross reference | Weighted score | Related literatures |
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Xenograft Model are used in the study 'Therapeutic targeting of PELP1 prevents ovarian cancer growth and metastasis.' (Chakravarty D et al., 2011).
Mouse Model are used in the study 'Therapeutic EphA2 gene targeting in vivo using neutral liposomal small interfering RNA delivery.' (Landen CN et al., 2005).
| Model | Cross reference | Weighted score | Related literatures |
|---|
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Vácha R et al. | Mechanism of interaction of monovalent ions with phosphatidylcholine lipid membranes. | 2010 | J Phys Chem B | pmid:20593888 |
| Juhasz J et al. | Fluorescent probe partitioning in giant unilamellar vesicles of 'lipid raft' mixtures. | 2010 | Biochem. J. | pmid:20642452 |
| Sullan RM et al. | Cholesterol-dependent nanomechanical stability of phase-segregated multicomponent lipid bilayers. | 2010 | Biophys. J. | pmid:20643069 |
| Sun Y et al. | Kinetic process of beta-amyloid formation via membrane binding. | 2010 | Biophys. J. | pmid:20643073 |
| Gardikis K et al. | New drug delivery nanosystem combining liposomal and dendrimeric technology (liposomal locked-in dendrimers) for cancer therapy. | 2010 | J Pharm Sci | pmid:20564386 |
| Fernández ML et al. | Structural and kinetic molecular dynamics study of electroporation in cholesterol-containing bilayers. | 2010 | J Phys Chem B | pmid:20429602 |
| Hirano A et al. | Structure changes of natively disordered Humanin in the presence of lipid. | 2010 | Int. J. Biol. Macromol. | pmid:20116397 |
| Tumaneng PW et al. | Lateral organization of complex lipid mixtures from multiscale modeling. | 2010 | J Chem Phys | pmid:20151760 |
| Yoon YZ et al. | Mechanical properties of ternary lipid membranes near a liquid-liquid phase separation boundary. | 2010 | J Phys Condens Matter | pmid:21389358 |
| Gerlach H et al. | HIV-1 Nef membrane association depends on charge, curvature, composition and sequence. | 2010 | Nat. Chem. Biol. | pmid:19935658 |
| Brewer J et al. | Multiphoton excitation fluorescence microscopy in planar membrane systems. | 2010 | Biochim. Biophys. Acta | pmid:20226161 |
| Haldar S et al. | Membrane interaction of the N-terminal domain of chemokine receptor CXCR1. | 2010 | Biochim. Biophys. Acta | pmid:20226759 |
| Zaitseva E et al. | Sequential rearrangement of interhelical networks upon rhodopsin activation in membranes: the Meta II(a) conformational substate. | 2010 | J. Am. Chem. Soc. | pmid:20230054 |
| Ip S et al. | Phase segregation of untethered zwitterionic model lipid bilayers observed on mercaptoundecanoic-acid-modified gold by AFM imaging and force mapping. | 2010 | Langmuir | pmid:20387821 |
| Klacsová M et al. | Molecular and component volumes of saturated n-alkanols in DOPC+DOPS bilayers. | 2010 | Chem. Phys. Lipids | pmid:20399763 |
| Thomas R et al. | Influence of proline upon the folding and geometry of the WALP19 transmembrane peptide. | 2009 | Biochemistry | pmid:19891499 |
| Schmidt ML et al. | Phase equilibria in DOPC/DPPC: Conversion from gel to subgel in two component mixtures. | 2009 | J Chem Phys | pmid:19895044 |
| Heuvingh J and Bonneau S | Asymmetric oxidation of giant vesicles triggers curvature-associated shape transition and permeabilization. | 2009 | Biophys. J. | pmid:19948119 |
| Herce HD et al. | Arginine-rich peptides destabilize the plasma membrane, consistent with a pore formation translocation mechanism of cell-penetrating peptides. | 2009 | Biophys. J. | pmid:19804722 |
| Pan J et al. | Alamethicin aggregation in lipid membranes. | 2009 | J. Membr. Biol. | pmid:19789905 |
| Hac-Wydro K et al. | Effect of saturation degree on the interactions between fatty acids and phosphatidylcholines in binary and ternary Langmuir monolayers. | 2009 | Colloids Surf B Biointerfaces | pmid:19398194 |
| Cabré EJ et al. | Surfactant protein SP-B strongly modifies surface collapse of phospholipid vesicles: insights from a quartz crystal microbalance with dissipation. | 2009 | Biophys. J. | pmid:19651035 |
| Shearman GC et al. | A 3-D hexagonal inverse micellar lyotropic phase. | 2009 | J. Am. Chem. Soc. | pmid:19146371 |
| Meledandri CJ et al. | Interpretation of molecular dynamics on different time scales in unilamellar vesicles using field-cycling NMR relaxometry. | 2009 | J Phys Chem B | pmid:19886620 |
| Efrat M et al. | Di-oleoyl phosphatidylcholine (PC-18:1) stimulates paraoxonase 1 (PON1) enzymatic and biological activities: in vitro and in vivo studies. | 2009 | Atherosclerosis | pmid:18585720 |
| Babu S et al. | Effect of size at the nanoscale and bilayer rigidity on skin diffusion of liposomes. | 2009 | J Biomed Mater Res A | pmid:18770522 |
| Hatzakis NS et al. | How curved membranes recruit amphipathic helices and protein anchoring motifs. | 2009 | Nat. Chem. Biol. | pmid:19749743 |
| Razpotnik A et al. | A new cytolytic protein from the sea anemone Urticina crassicornis that binds to cholesterol- and sphingomyelin-rich membranes. | 2009 | Toxicon | pmid:19232528 |
| Davis JH et al. | Phase equilibria in DOPC/DPPC-d62/cholesterol mixtures. | 2009 | Biophys. J. | pmid:19167302 |
| Tamba Y and Yamazaki M | Magainin 2-induced pore formation in the lipid membranes depends on its concentration in the membrane interface. | 2009 | J Phys Chem B | pmid:19267489 |
| Oreopoulos J and Yip CM | Combinatorial microscopy for the study of protein-membrane interactions in supported lipid bilayers: Order parameter measurements by combined polarized TIRFM/AFM. | 2009 | J. Struct. Biol. | pmid:19268707 |
| Bonechi C et al. | Study of bradykinin conformation in the presence of model membrane by Nuclear Magnetic Resonance and molecular modelling. | 2009 | Biochim. Biophys. Acta | pmid:19272336 |
| Negishi M et al. | Emergence of superstructures from a homogeneous lipid sphere. | 2009 | J Phys Chem B | pmid:19243102 |
| Lamberson ER et al. | Path dependence of three-phase or two-phase end points in fluid binary lipid mixtures. | 2009 | J Phys Chem B | pmid:19243147 |
| Pan J et al. | Alamethicin in lipid bilayers: combined use of X-ray scattering and MD simulations. | 2009 | Biochim. Biophys. Acta | pmid:19248763 |
| Oreopoulos J and Yip CM | Probing membrane order and topography in supported lipid bilayers by combined polarized total internal reflection fluorescence-atomic force microscopy. | 2009 | Biophys. J. | pmid:19254557 |
| Nordlund G et al. | Formation of supported lipid bilayers on silica particles studied using flow cytometry. | 2009 | Langmuir | pmid:19265407 |
| Tsumoto K et al. | Efficient formation of giant liposomes through the gentle hydration of phosphatidylcholine films doped with sugar. | 2009 | Colloids Surf B Biointerfaces | pmid:18993037 |
| Zidovska A et al. | Block liposomes from curvature-stabilizing lipids: connected nanotubes, -rods, or -spheres. | 2009 | Langmuir | pmid:18834165 |
| Santos O and Arnebrant T | Silica supported phospholipid layers doped with GM1: A comparison between different methods. | 2009 | J Colloid Interface Sci | pmid:18950789 |
| Sasaki H and White SH | A novel fluorescent probe that senses the physical state of lipid bilayers. | 2009 | Biophys. J. | pmid:19486685 |
| Vácha R et al. | Effects of alkali cations and halide anions on the DOPC lipid membrane. | 2009 | J Phys Chem A | pmid:19290591 |
| Bernchou U et al. | Growth of solid domains in model membranes: quantitative image analysis reveals a strong correlation between domain shape and spatial position. | 2009 | J Phys Chem B | pmid:19296622 |
| Zidovska A et al. | The role of cholesterol and structurally related molecules in enhancing transfection of cationic liposome-DNA complexes. | 2009 | J Phys Chem B | pmid:19354307 |
| Drechsler A et al. | Effect of lipid on the conformation of the N-terminal region of equinatoxin II: a synchrotron radiation circular dichroism spectroscopic study. | 2009 | Eur. Biophys. J. | pmid:19343335 |
| Ariola FS et al. | Membrane fluidity and lipid order in ternary giant unilamellar vesicles using a new bodipy-cholesterol derivative. | 2009 | Biophys. J. | pmid:19348752 |
| Ira S et al. | Enzymatic generation of ceramide induces membrane restructuring: Correlated AFM and fluorescence imaging of supported bilayers. | 2009 | J. Struct. Biol. | pmid:19348948 |
| Yu Y and Granick S | Pearling of lipid vesicles induced by nanoparticles. | 2009 | J. Am. Chem. Soc. | pmid:19775107 |
| Patel GJ et al. | The periplasmic chaperone Skp facilitates targeting, insertion, and folding of OmpA into lipid membranes with a negative membrane surface potential. | 2009 | Biochemistry | pmid:19780589 |
| Kita-Tokarczyk K et al. | Monolayer interactions between lipids and amphiphilic block copolymers. | 2009 | Langmuir | pmid:19705885 |
| Dabkowska AP et al. | Specular neutron reflectivity studies of the interaction of cytochrome c with supported phosphatidylcholine bilayers doped with phosphatidylserine. | 2009 | Langmuir | pmid:19714900 |
| Greiner AJ et al. | Effect of hydrogen bonding on the rotational and translational dynamics of a headgroup-bound chromophore in bilayer lipid membranes. | 2009 | J Phys Chem B | pmid:19761197 |
| El Kirat K and Morandat S | Cytochrome c interaction with neutral lipid membranes: influence of lipid packing and protein charges. | 2009 | Chem. Phys. Lipids | pmid:19699729 |
| Bernchou U et al. | Texture of lipid bilayer domains. | 2009 | J. Am. Chem. Soc. | pmid:19702259 |
| Kent B et al. | The inverse hexagonal - inverse ribbon - lamellar gel phase transition sequence in low hydration DOPC:DOPE phospholipid mixtures. | 2009 | Chem. Phys. Lipids | pmid:19026619 |
| Beales PA and Vanderlick TK | Partitioning of membrane-anchored DNA between coexisting lipid phases. | 2009 | J Phys Chem B | pmid:19827842 |
| RodrÃguez Niño MR et al. | Structural, topographical, and rheological characteristics of beta-casein-dioleoyl phosphatidylcholine (DOPC) mixed monolayers. | 2009 | Colloids Surf B Biointerfaces | pmid:19056249 |
| Miñones J et al. | Interactions between membrane sterols and phospholipids in model mammalian and fungi cellular membranes--a Langmuir monolayer study. | 2009 | Biophys. Chem. | pmid:19073357 |
| Weise K et al. | Influence of the lipidation motif on the partitioning and association of N-Ras in model membrane subdomains. | 2009 | J. Am. Chem. Soc. | pmid:19133719 |
| Domenici F et al. | Alamethicin-lipid interaction studied by energy dispersive X-ray diffraction. | 2009 | Colloids Surf B Biointerfaces | pmid:19135341 |
| Lu L and Voth GA | Systematic coarse-graining of a multicomponent lipid bilayer. | 2009 | J Phys Chem B | pmid:19138138 |
| Polyansky AA et al. | Adaptation of a membrane-active peptide to heterogeneous environment. II. The role of mosaic nature of the membrane surface. | 2009 | J Phys Chem B | pmid:19125636 |
| Polyansky AA et al. | Adaptation of a membrane-active peptide to heterogeneous environment. I. Structural plasticity of the peptide. | 2009 | J Phys Chem B | pmid:19125640 |
| Ghosh B et al. | Solubilization, purification, and reconstitution of alpha 2 beta 1 isozyme of Na+/K+ -ATPase from caveolae of pulmonary smooth muscle plasma membrane: comparative studies with DHPC, C12E8, and Triton X-100. | 2009 | Mol. Cell. Biochem. | pmid:19101784 |
| Yaroslavov AA et al. | Biomembrane sensitivity to structural changes in bound polymers. | 2009 | J. Am. Chem. Soc. | pmid:19152326 |
| Schuy S et al. | Coiled-coil lipopeptides mimicking the prehairpin intermediate of glycoprotein gp41. | 2009 | Angew. Chem. Int. Ed. Engl. | pmid:19090512 |
| Kar P et al. | mu-Calpain mediated cleavage of the Na+/Ca2+ exchanger in isolated mitochondria under A23187 induced Ca2+ stimulation. | 2009 | Arch. Biochem. Biophys. | pmid:19094959 |
| Blicher A et al. | The temperature dependence of lipid membrane permeability, its quantized nature, and the influence of anesthetics. | 2009 | Biophys. J. | pmid:19486680 |
| Wunderlich B et al. | Phase-state dependent current fluctuations in pure lipid membranes. | 2009 | Biophys. J. | pmid:19486681 |
| Mojzisova H et al. | Photosensitizing properties of chlorins in solution and in membrane-mimicking systems. | 2009 | Photochem. Photobiol. Sci. | pmid:19492105 |
| Traaseth NJ et al. | Structure and topology of monomeric phospholamban in lipid membranes determined by a hybrid solution and solid-state NMR approach. | 2009 | Proc. Natl. Acad. Sci. U.S.A. | pmid:19509339 |
| Filippov A et al. | Effect of NaCl and CaCl(2) on the lateral diffusion of zwitterionic and anionic lipids in bilayers. | 2009 | Chem. Phys. Lipids | pmid:19477314 |
| Garvik O et al. | The fluorescent cholesterol analog dehydroergosterol induces liquid-ordered domains in model membranes. | 2009 | Chem. Phys. Lipids | pmid:19477318 |
| Yesylevskyy S et al. | Alternative mechanisms for the interaction of the cell-penetrating peptides penetratin and the TAT peptide with lipid bilayers. | 2009 | Biophys. J. | pmid:19580742 |
| Jo S et al. | CHARMM-GUI Membrane Builder for mixed bilayers and its application to yeast membranes. | 2009 | Biophys. J. | pmid:19580743 |
| Zidovska A et al. | The effect of salt and pH on block liposomes studied by cryogenic transmission electron microscopy. | 2009 | Biochim. Biophys. Acta | pmid:19559003 |
| Mills TT et al. | Effects of cholesterol and unsaturated DOPC lipid on chain packing of saturated gel-phase DPPC bilayers. | 2009 | Gen. Physiol. Biophys. | pmid:19592709 |
| Ho YF et al. | Lipid-mediated preferential localization of hypericin in lipid membranes. | 2009 | Biochim. Biophys. Acta | pmid:19366588 |
| Le Bihan O et al. | Cryo-electron tomography of nanoparticle transmigration into liposome. | 2009 | J. Struct. Biol. | pmid:19596070 |
| Aeffner S et al. | Membrane fusion intermediates and the effect of cholesterol: an in-house X-ray scattering study. | 2009 | Eur Phys J E Soft Matter | pmid:19533189 |
| Zidovska A et al. | Liquid crystalline phases of dendritic lipid-DNA self-assemblies: lamellar, hexagonal, and DNA bundles. | 2009 | J Phys Chem B | pmid:19673065 |
| Stefl M et al. | Simultaneous characterization of lateral lipid and prothrombin diffusion coefficients by z-scan fluorescence correlation spectroscopy. | 2009 | Biophys. J. | pmid:19651025 |
| Allen KB and Layton BE | Determination of the forces imposed by micro and nanopipettes during DOPC: DOPS liposome manipulation. | 2009 | Chem. Phys. Lipids | pmid:19665459 |
| Weinrich M et al. | Lipid-dependent effects of halothane on gramicidin channel kinetics: a new role for lipid packing stress. | 2009 | Biochemistry | pmid:19405539 |
| Simonzadeh N | An isocratic HPLC method for the simultaneous determination of cholesterol, cardiolipin, and DOPC in lyophilized lipids and liposomal formulations. | 2009 | J Chromatogr Sci | pmid:19406017 |
| Wada-Katsumata A et al. | Behavioral and electrophysiological studies on the sexually biased synergism between oligosaccharides and phospholipids in gustatory perception of nuptial secretion by the German cockroach. | 2009 | J. Insect Physiol. | pmid:19422830 |
| Protopapa E et al. | Interaction of self-assembling beta-sheet peptides with phospholipid monolayers: the role of aggregation state, polarity, charge and applied field. | 2009 | Langmuir | pmid:19437790 |
| Litt J et al. | Enhancing protein stability by adsorption onto raftlike lipid domains. | 2009 | J. Am. Chem. Soc. | pmid:19385631 |
| Shi L et al. | Tilt and azimuthal angles of a transmembrane peptide: a comparison between molecular dynamics calculations and solid-state NMR data of sarcolipin in lipid membranes. | 2009 | Biophys. J. | pmid:19413970 |
| Huang HW | Free energies of molecular bound states in lipid bilayers: lethal concentrations of antimicrobial peptides. | 2009 | Biophys. J. | pmid:19383470 |
| Mereuta L et al. | The role played by lipids unsaturation upon the membrane interaction of the Helicobacter pylori HP(2-20) antimicrobial peptide analogue HPA3. | 2009 | J. Bioenerg. Biomembr. | pmid:19294495 |
| Tielrooij KJ et al. | Dielectric relaxation dynamics of water in model membranes probed by terahertz spectroscopy. | 2009 | Biophys. J. | pmid:19883591 |
| Juhasz J et al. | Quantitative characterization of coexisting phases in DOPC/DPPC/cholesterol mixtures: comparing confocal fluorescence microscopy and deuterium nuclear magnetic resonance. | 2009 | Biochim. Biophys. Acta | pmid:19837045 |
| Koklic T et al. | Factor XA binding to phosphatidylserine-containing membranes produces an inactive membrane-bound dimer. | 2009 | Biophys. J. | pmid:19843455 |
| Yoo J and Cui Q | Curvature generation and pressure profile modulation in membrane by lysolipids: insights from coarse-grained simulations. | 2009 | Biophys. J. | pmid:19843459 |
| Sanders M et al. | Pulsed field gradient nuclear magnetic resonance study of time-dependent diffusion behavior and exchange of lipids in planar-supported lipid bilayers. | 2009 | J Phys Chem B | pmid:19795901 |
| Chalbot S et al. | Cerebrospinal fluid secretory Ca2+-dependent phospholipase A2 activity is increased in Alzheimer disease. | 2009 | Clin. Chem. | pmid:19850632 |
| Zidovska A et al. | Block liposomes vesicles of charged lipids with distinctly shaped nanoscale sphere-, pear-, tube-, or rod-segments. | 2009 | Meth. Enzymol. | pmid:19913164 |
| Arkhipov A et al. | Membrane-bending mechanism of amphiphysin N-BAR domains. | 2009 | Biophys. J. | pmid:19917226 |
| Gasecka A et al. | Quantitative imaging of molecular order in lipid membranes using two-photon fluorescence polarimetry. | 2009 | Biophys. J. | pmid:19917241 |