1,2-Dioleoyl-sn-Glycero-3-Phosphocholine is a lipid of Glycerophospholipids (GP) class. 1,2-dioleoyl-sn-glycero-3-phosphocholine is associated with abnormalities such as Exanthema, Renal tubular disorder, Nodule, Gigantism and Mycoses. The involved functions are known as Lysis, Encapsulation, Process, Uptake and Flow or discharge. 1,2-dioleoyl-sn-glycero-3-phosphocholine often locates in Cytoplasmic matrix, Endosomes, soluble, Endoplasmic Reticulum and Membrane. The associated genes with 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine are P4HTM gene, synthetic peptide, BCAR1 gene, PCNA gene and CNTNAP1 gene. The related lipids are Liposomes, 1,2-oleoylphosphatidylcholine, 1,2-distearoylphosphatidylethanolamine, Butanols and Cardiolipins. The related experimental models are Mouse Model and Xenograft Model.
To understand associated biological information of 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
1,2-Dioleoyl-sn-Glycero-3-Phosphocholine is suspected in Gigantism, Nodule, protrusion, DERMATITIS HERPETIFORMIS, FAMILIAL, Exanthema, Renal tubular disorder and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Edema | D004487 | 152 associated lipids |
| Hemolysis | D006461 | 131 associated lipids |
| Atherosclerosis | D050197 | 85 associated lipids |
| Neuroblastoma | D009447 | 66 associated lipids |
| Niemann-Pick Diseases | D009542 | 25 associated lipids |
| Celiac Disease | D002446 | 16 associated lipids |
| Respiratory Syncytial Virus Infections | D018357 | 10 associated lipids |
| Ovarian Neoplasms | D010051 | 10 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
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| Function | Cross reference | Weighted score | Related literatures |
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| Lipid concept | Cross reference | Weighted score | Related literatures |
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| Gene | Cross reference | Weighted score | Related literatures |
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Xenograft Model are used in the study 'Therapeutic targeting of PELP1 prevents ovarian cancer growth and metastasis.' (Chakravarty D et al., 2011).
Mouse Model are used in the study 'Therapeutic EphA2 gene targeting in vivo using neutral liposomal small interfering RNA delivery.' (Landen CN et al., 2005).
| Model | Cross reference | Weighted score | Related literatures |
|---|
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Woźniak M et al. | Diversity of the effect of phosphatidylcholine and sphingomyelin on adenylate deaminase from pig brain. | 1987 | Acta Biochim. Pol. | pmid:3687300 |
| King GI and White SH | Determining bilayer hydrocarbon thickness from neutron diffraction measurements using strip-function models. | 1986 | Biophys. J. | pmid:3708089 |
| Benz R and Conti F | Effects of hydrostatic pressure on lipid bilayer membranes. I. Influence on membrane thickness and activation volumes of lipophilic ion transport. | 1986 | Biophys. J. | pmid:3730509 |
| Ellens H et al. | Fusion of phosphatidylethanolamine-containing liposomes and mechanism of the L alpha-HII phase transition. | 1986 | Biochemistry | pmid:3741846 |
| Hwang F et al. | Anisodamine induces the hexagonal phase in phospholipid liposomes. | 1986 | Biochim. Biophys. Acta | pmid:3741870 |
| Schwarz G et al. | Thermodynamic analysis of incorporation and aggregation in a membrane: application to the pore-forming peptide alamethicin. | 1986 | Biochim. Biophys. Acta | pmid:3756150 |
| van Duijn G et al. | Dolichyl phosphate induces non-bilayer structures, vesicle fusion and transbilayer movement of lipids: a model membrane study. | 1986 | Biochim. Biophys. Acta | pmid:3756157 |
| Isaacs BS et al. | A domain of membrane-bound blood coagulation factor Va is located far from the phospholipid surface. A fluorescence energy transfer measurement. | 1986 | Biochemistry | pmid:3768326 |
| Hantz E et al. | The osmotic response of large unilamellar vesicles studied by quasielastic light scattering. | 1986 | Biochim. Biophys. Acta | pmid:3778898 |
| Connor J et al. | Biodistribution of pH-sensitive immunoliposomes. | 1986 | Biochim. Biophys. Acta | pmid:3778935 |
| Lindhout T et al. | Thrombin generation and inactivation in the presence of antithrombin III and heparin. | 1986 | Biochemistry | pmid:3790498 |
| Leventis R et al. | Divalent cation induced fusion and lipid lateral segregation in phosphatidylcholine-phosphatidic acid vesicles. | 1986 | Biochemistry | pmid:3801406 |
| Chefurka W et al. | Perturbation of phospholipid bilayers by DDT. | 1987 | Biochim. Biophys. Acta | pmid:3801467 |
| Martin TW et al. | Phosphatidylcholine metabolism in endothelial cells: evidence for phospholipase A and a novel Ca2+-independent phospholipase C. | 1987 | Biochim. Biophys. Acta | pmid:3801504 |
| Nicolay K et al. | Ethylene glycol causes acyl chain disordering in liquid-crystalline, unsaturated phospholipid model membranes, as measured by 2H NMR. | 1986 | FEBS Lett. | pmid:3803574 |
| Gao K and Huang L | Solid core liposomes with encapsulated colloidal gold particles. | 1987 | Biochim. Biophys. Acta | pmid:3814593 |
| Smaal EB et al. | 2H-NMR, 31P-NMR and DSC characterization of a novel lipid organization in calcium-dioleoylphosphatidate membranes. Implications for the mechanism of the phosphatidate calcium transmembrane shuttle. | 1987 | Biochim. Biophys. Acta | pmid:3814595 |
| van Liempd JP et al. | Nonselective squeeze-out of dioleoylphosphatidylcholine and dioleoylphosphatidylglycerol from binary mixed monolayers with dipalmitoylphosphatidylcholine. | 1987 | Biochim. Biophys. Acta | pmid:3814598 |
| Tajima K and Gershfeld NL | Phospholipid surface bilayers at the air-water interface. I. Thermodynamic properties. | 1985 | Biophys. J. | pmid:3838485 |
| Steinmetz A and Utermann G | Activation of lecithin: cholesterol acyltransferase by human apolipoprotein A-IV. | 1985 | J. Biol. Chem. | pmid:3918999 |
| Smaal EB et al. | Essential adaptation of the calcium influx assay into liposomes with entrapped arsenazo III for studies on the possible calcium translocating properties of acidic phospholipids. | 1985 | Biochim. Biophys. Acta | pmid:3924100 |
| Yeagle PL | Lanosterol and cholesterol have different effects on phospholipid acyl chain ordering. | 1985 | Biochim. Biophys. Acta | pmid:3986200 |
| Connor J and Huang L | Efficient cytoplasmic delivery of a fluorescent dye by pH-sensitive immunoliposomes. | 1985 | J. Cell Biol. | pmid:4019583 |
| Gallay J et al. | Cardiolipin vesicles can accommodate cholesterol up to 0.80 mole fraction, i.e. one molecule per cardiolipin fatty acid chain. | 1985 | FEBS Lett. | pmid:4054299 |
| Wilschut J et al. | Kinetics of Ca2+-induced fusion of cardiolipin-phosphatidylcholine vesicles: correlation between vesicle aggregation, bilayer destabilization, and fusion. | 1985 | Biochemistry | pmid:4063345 |
| Yoshikawa K et al. | Unique electronic property of a Langmuir-Blodgett film of dioleyl lecithin deposited on a porous membrane. | 1985 | Biochem. Biophys. Res. Commun. | pmid:4084294 |
| Kubo M and Hostetler KY | Mechanism of cationic amphiphilic drug inhibition of purified lysosomal phospholipase A1. | 1985 | Biochemistry | pmid:4084534 |
| Campbell IM and Pawagi AB | Temperature-dependent interactions between poly-L-lysine and phosphatidylcholine vesicles. | 1979 | Can. J. Biochem. | pmid:44221 |
| Podack ER et al. | Membrane attach complex of complement (MAC): three-dimensional analysis of MAC-phospholipid vesicle recombinants. | 1982 | J. Immunol. | pmid:6174630 |
| Gambale F et al. | GM1 micelles modify the transport properties of the ionophore gramicidin D in artificial planar bilayers. | 1984 | J. Neurosci. Res. | pmid:6209414 |
| Kaizu T et al. | A saturation transfer electron spin resonance study on the break in the Arrhenius plot for the rotational motion of Ca2+-dependent adenosine triphosphatase molecules in purified and lipid-replaced preparations of rabbit skeletal muscle sarcoplasmic reticulum. | 1980 | J. Biochem. | pmid:6257672 |
| Gögelein H et al. | The effect of lanthanum on alamethicin channels in black lipid bilayers. | 1981 | Biochim. Biophys. Acta | pmid:6260169 |
| Kinosita K et al. | The effect of cytochrome oxidase on lipid chain dynamics. A nanosecond fluorescence depolarization study. | 1981 | Biochim. Biophys. Acta | pmid:6271207 |
| Heitz F and Spach G | Ionic channels of some glycine-rich synthetic polypeptides. | 1982 | Biochem. Biophys. Res. Commun. | pmid:6284141 |
| Hoekstra D | Topographical distribution of a membrane-inserted fluorescent phospholipid analogue during cell fusion. | 1983 | Exp. Cell Res. | pmid:6301868 |
| Madden TD et al. | Lipid requirements for coupled cytochrome oxidase vesicles. | 1983 | Biochemistry | pmid:6303398 |
| Sandermann H and Gottwald BA | Cooperative lipid activation of (Na+ + K+)-ATPASE as a consequence of non-cooperative lipid-protein interactions. | 1983 | Biochim. Biophys. Acta | pmid:6307366 |
| Gremlich HU et al. | Conformational changes of adrenocorticotropin peptides upon interaction with lipid membranes revealed by infrared attenuated total reflection spectroscopy. | 1983 | Biochemistry | pmid:6313037 |
| Madden TD and Cullis PR | Detergent-induced solubilization of cytochrome c oxidase as detected in a novel reconstituted system. | 1984 | J. Biol. Chem. | pmid:6330068 |
| Hidalgo C et al. | Uncoupling of Ca2+ transport in sarcoplasmic reticulum as a result of labeling lipid amino groups and inhibition of Ca2+-ATPase activity by modification of lysine residues of the Ca2+-ATPase polypeptide. | 1982 | J. Biol. Chem. | pmid:6458613 |
| Resseguie WD and Hughes BL | Catabolism of phospholipids by chicken seminal components after storage. | 1984 | Poult. Sci. | pmid:6483728 |
| Kop JM et al. | The adsorption of prothrombin to phospholipid monolayers quantitated by ellipsometry. | 1984 | J. Biol. Chem. | pmid:6501285 |
| Usai C et al. | Effect of gangliosides on phospholipid bilayers: a study with the lipophilic ions relaxation method. | 1984 | J. Membr. Biol. | pmid:6502698 |
| Peters MW et al. | Lateral distribution of gangliosides in bilayer membranes: lipid and ionic effects. | 1984 | J. Neurosci. Res. | pmid:6548772 |
| Usai C et al. | Capacitance--voltage relationship in phospholipid bilayers containing gangliosides. | 1983 | FEBS Lett. | pmid:6617861 |
| Van der Steen AT et al. | Barrier properties of glycophorin-phospholipid systems prepared by different methods. | 1983 | Biochim. Biophys. Acta | pmid:6688359 |
| Duportail G and Weinreb A | Photochemical changes of fluorescent probes in membranes and their effect on the observed fluorescence anisotropy values. | 1983 | Biochim. Biophys. Acta | pmid:6689128 |
| Stein Y et al. | Metabolism of liposomes prepared from a labelled ether analog of 1,2-dioleoyl-sn-glycero-3-phosphocholine in the rat. | 1984 | Biochim. Biophys. Acta | pmid:6712973 |
| Chong PL and Cossins AR | Interacting effects of temperature, pressure and cholesterol content upon the molecular order of dioleoylphosphatidylcholine vesicles. | 1984 | Biochim. Biophys. Acta | pmid:6722144 |
| Blumenthal R et al. | Clathrin-induced pH-dependent fusion of phosphatidylcholine vesicles. | 1983 | J. Biol. Chem. | pmid:6826567 |
| van de Waart P et al. | Interaction of bovine blood clotting factor Va and its subunits with phospholipid vesicles. | 1983 | Biochemistry | pmid:6860639 |
| Tsao FH | Specific transfer of dipalmitoyl phosphatidylcholine in rabbit lung. | 1980 | Biochim. Biophys. Acta | pmid:6893283 |
| Notter RH et al. | Bilirubin interactions with phospholipid components of lung surfactant. | 1982 | Pediatr. Res. | pmid:6895780 |
| Notter RH et al. | Hysteresis in saturated phospholipid films and its potential relevance for lung surfactant function in vivo. | 1982 | Exp. Lung Res. | pmid:6896686 |
| Trudell JR et al. | Reductive metabolism of carbon tetrachloride by human cytochromes P-450 reconstituted in phospholipid vesicles: mass spectral identification of trichloromethyl radical bound to dioleoyl phosphatidylcholine. | 1982 | Proc. Natl. Acad. Sci. U.S.A. | pmid:6953422 |
| Taraschi TF et al. | Effect of glycophorin on lipid polymorphism. A 31P-NMR study. | 1982 | Biochim. Biophys. Acta | pmid:7059597 |
| Kempf C et al. | Voltage-dependent trans-bilayer orientation of melittin. | 1982 | J. Biol. Chem. | pmid:7061434 |
| Goll J et al. | Photon correlation spectroscopic study of the size distribution of phospholipid vesicles. | 1982 | Biophys. J. | pmid:7074200 |
| Yoshikami S and Nöll GN | Technique for introducing retinol analogs into the isolated retina. | 1982 | Meth. Enzymol. | pmid:7098891 |
| Tilcock CP et al. | Influence of cholesterol on the structural preferences of dioleoylphosphatidylethanolamine-dioleoylphosphatidylcholine systems: a phosphorus-31 and deuterium nuclear magnetic resonance study. | 1982 | Biochemistry | pmid:7138819 |
| De Kruijff B et al. | Further aspects of the Ca2+-dependent polymorphism of bovine heart cardiolipin. | 1982 | Biochim. Biophys. Acta | pmid:7150583 |
| Gambale F et al. | Properties of ionic transport through phospholipid-glycolipid artificial bilayers. | 1982 | Biochim. Biophys. Acta | pmid:7150587 |
| Hermetter A and Paltauf F | Interaction of enantiomeric alkylacyl and diacylglycero-phosphocholines with cholesterol in bilayer membranes. | 1982 | Chem. Phys. Lipids | pmid:7172344 |
| Schindler H | Formation of planar bilayers from artificial or native membrane vesicles. | 1980 | FEBS Lett. | pmid:7194191 |
| Smaby JM and Brockman HL | Novel surface phase containing cholesteryl esters. 1. Structural characteristics determined from surface pressure--area measurements. | 1981 | Biochemistry | pmid:7213605 |
| Sandra A et al. | Morphological differentiation of murine neuroblastoma induced by liposomes. Lipid specificity and pathway of liposome uptake. | 1981 | Exp. Cell Res. | pmid:7215457 |
| Seelig J et al. | Deuterium and phosphorus nuclear magnetic resonance and fluorescence depolarization studies of functional reconstituted sarcoplasmic reticulum membrane vesicles. | 1981 | Biochemistry | pmid:7272285 |
| Parker RJ et al. | Effect of liposome encapsulation of a fluorescent dye on its uptake by the lymphatics of the rat. | 1981 | Pharmacology | pmid:7280007 |
| Ralston E et al. | Lysophosphatidylcholine in liposomal membranes: enhanced permeability but little effect on transfer of a water-soluble fluorescent marker into human lymphocytes. | 1980 | Biochim. Biophys. Acta | pmid:7378402 |
| Lakowicz JR and Anderson CJ | Permeability of lipid bilayers to methylmercuric chloride: quantification by fluorescence quenching of a carbazole-labeled phospholipid. | 1980 | Chem. Biol. Interact. | pmid:7379210 |
| Rouet-Mayer MA et al. | Critical analysis of phospholipid hydrolyzing activities in ripening tomato fruits. Study by spectrofluorimetry and high-performance liquid chromatography. | 1995 | Lipids | pmid:7475990 |
| Richieri GV and Kleinfeld AM | Continuous measurement of phospholipase A2 activity using the fluorescent probe ADIFAB. | 1995 | Anal. Biochem. | pmid:7485980 |
| Webb MS et al. | Effects of plant sterols on the hydration and phase behavior of DOPE/DOPC mixtures. | 1995 | Biochim. Biophys. Acta | pmid:7488628 |
| Mavromoustakos T et al. | Effects of the anesthetic steroid alphaxalone and its inactive delta 16-analog on the thermotropic properties of membrane bilayers. A model for membrane perturbation. | 1995 | Biochim. Biophys. Acta | pmid:7488631 |
| Mukherjee S and Chattopadhyay A | Motionally restricted tryptophan environments at the peptide-lipid interface of gramicidin channels. | 1994 | Biochemistry | pmid:7513554 |
| ter Beest MB et al. | Reconstitution of proteolipid protein: some properties and its role in interlamellar attachment. | 1994 | Biochem. J. | pmid:7516154 |
| Duff KC et al. | Neutron diffraction reveals the site of amantadine blockade in the influenza A M2 ion channel. | 1994 | Virology | pmid:7516598 |
| Myers RL and Chiu IM | Single primer-mediated polymerase chain reaction. | 1994 | Methods Mol. Biol. | pmid:7522831 |
| Jaikaran DC et al. | C-terminal amino groups facilitate membrane incorporation of gramicidin derivatives. | 1995 | Biochim. Biophys. Acta | pmid:7533540 |
| Muller JM et al. | Effect of gramicidin A on structure and dynamics of lipid vesicle bilayers. A time-resolved fluorescence depolarization study. | 1995 | Biochemistry | pmid:7534479 |
| Ohman A et al. | Solvent stabilized solution structures of galanin and galanin analogs, studied by circular dichroism spectroscopy. | 1995 | Biochim. Biophys. Acta | pmid:7540871 |
| Mach H and Middaugh CR | Interaction of partially structured states of acidic fibroblast growth factor with phospholipid membranes. | 1995 | Biochemistry | pmid:7543282 |
| Billy D et al. | Inhibition of prothrombinase at macroscopic lipid membranes: competition between antithrombin and prothrombin. | 1995 | Biochemistry | pmid:7577961 |
| Méthot N et al. | Structure of both the ligand- and lipid-dependent channel-inactive states of the nicotinic acetylcholine receptor probed by FTIR spectroscopy and hydrogen exchange. | 1995 | Biochemistry | pmid:7578128 |
| Janas T and Janas T | Interaction of undecaprenyl phosphate with phospholipid bilayers. | 1995 | Chem. Phys. Lipids | pmid:7586095 |
| Parasassi T et al. | Cholesterol protects the phospholipid bilayer from oxidative damage. | 1995 | Free Radic. Biol. Med. | pmid:7590402 |
| Guilarte TR et al. | Biochemical evidence of an interaction of lead at the zinc allosteric sites of the NMDA receptor complex: effects of neuronal development. | 1995 | Neurotoxicology | pmid:7603646 |
| Seppen J et al. | Immunoaffinity purification and reconstitution of the human bilirubin/phenol UDP-glucuronosyltransferase family. | 1995 | Protein Expr. Purif. | pmid:7606162 |
| Li H et al. | Characterization of the pre-mRNA binding site for yeast ribosomal protein L32: the importance of a purine-rich internal loop. | 1995 | J. Mol. Biol. | pmid:7616567 |
| Giesen PL et al. | Production of thrombin as a probe for mixing of phospholipids in membranes on solid supports. | 1995 | Biochim. Biophys. Acta | pmid:7619841 |
| Huang P and Loew GH | Interaction of an amphiphilic peptide with a phospholipid bilayer surface by molecular dynamics simulation study. | 1995 | J. Biomol. Struct. Dyn. | pmid:7626245 |
| Anachi RB et al. | Molecular modeling studies on amphotericin B and its complex with phospholipid. | 1995 | J. Biomol. Struct. Dyn. | pmid:7626246 |
| Turner DC et al. | Thermodynamics of interaction of the fusion-inhibiting peptide Z-D-Phe-L-Phe-Gly with dioleoylphosphatidylcholine vesicles: direct calorimetric determination. | 1995 | Biochemistry | pmid:7626621 |
| Vidal M and Hoekstra D | In vitro fusion of reticulocyte endocytic vesicles with liposomes. | 1995 | J. Biol. Chem. | pmid:7629083 |
| van den Besselaar AM | Phosphatidylethanolamine and phosphatidylserine synergistically promote heparin's anticoagulant effect. | 1995 | Blood Coagul. Fibrinolysis | pmid:7654938 |
| ter Beest MB and Hoekstra D | Interaction of myelin basic protein with artificial membranes. Parameters governing binding, aggregation and dissociation. | 1993 | Eur. J. Biochem. | pmid:7679637 |
| Woolley GA and Wallace BA | Temperature dependence of the interaction of alamethicin helices in membranes. | 1993 | Biochemistry | pmid:7690593 |
| Aranda FJ et al. | Capsaicin affects the structure and phase organization of phospholipid membranes. | 1995 | Biochim. Biophys. Acta | pmid:7696298 |
| Moring J et al. | Interaction of the NMDA receptor noncompetitive antagonist MK-801 with model and native membranes. | 1994 | Biophys. J. | pmid:7696477 |
| Schwarz D et al. | Direct visualization of a cardiolipin-dependent cytochrome P450scc-induced vesicle aggregation. | 1994 Nov-Dec | J. Struct. Biol. | pmid:7734245 |