1,2-Dioleoyl-sn-Glycero-3-Phosphocholine is a lipid of Glycerophospholipids (GP) class. 1,2-dioleoyl-sn-glycero-3-phosphocholine is associated with abnormalities such as Exanthema, Renal tubular disorder, Nodule, Gigantism and Mycoses. The involved functions are known as Lysis, Encapsulation, Process, Uptake and Flow or discharge. 1,2-dioleoyl-sn-glycero-3-phosphocholine often locates in Cytoplasmic matrix, Endosomes, soluble, Endoplasmic Reticulum and Membrane. The associated genes with 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine are P4HTM gene, synthetic peptide, BCAR1 gene, PCNA gene and CNTNAP1 gene. The related lipids are Liposomes, 1,2-oleoylphosphatidylcholine, 1,2-distearoylphosphatidylethanolamine, Butanols and Cardiolipins. The related experimental models are Mouse Model and Xenograft Model.
To understand associated biological information of 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
1,2-Dioleoyl-sn-Glycero-3-Phosphocholine is suspected in Gigantism, Nodule, protrusion, DERMATITIS HERPETIFORMIS, FAMILIAL, Exanthema, Renal tubular disorder and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Celiac Disease | D002446 | 16 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Hemolysis | D006461 | 131 associated lipids |
| Neuroblastoma | D009447 | 66 associated lipids |
| Niemann-Pick Diseases | D009542 | 25 associated lipids |
| Ovarian Neoplasms | D010051 | 10 associated lipids |
| Respiratory Syncytial Virus Infections | D018357 | 10 associated lipids |
| Atherosclerosis | D050197 | 85 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
| Gene | Cross reference | Weighted score | Related literatures |
|---|
Xenograft Model are used in the study 'Therapeutic targeting of PELP1 prevents ovarian cancer growth and metastasis.' (Chakravarty D et al., 2011).
Mouse Model are used in the study 'Therapeutic EphA2 gene targeting in vivo using neutral liposomal small interfering RNA delivery.' (Landen CN et al., 2005).
| Model | Cross reference | Weighted score | Related literatures |
|---|
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Ishigami T et al. | Effect of Boundary Edge in DOPC/DPPC/Cholesterol Liposomes on Acceleration of l-Histidine Preferential Adsorption. | 2016 | Langmuir | pmid:27232976 |
| Ngo AT and Cosa G | Assembly of zwitterionic phospholipid/conjugated polyelectrolyte complexes: structure and photophysical properties. | 2010 | Langmuir | pmid:20017509 |
| Ileri Ercan N et al. | Molecular Dynamics Modeling of Methylene Blue-DOPC Lipid Bilayer Interactions. | 2018 | Langmuir | pmid:29553270 |
| Vafaei S et al. | Hybrid Biomimetic Interfaces Integrating Supported Lipid Bilayers with Decellularized Extracellular Matrix Components. | 2018 | Langmuir | pmid:29489371 |
| Galluzzi M et al. | Interaction of imidazolium-based room-temperature ionic liquids with DOPC phospholipid monolayers: electrochemical study. | 2013 | Langmuir | pmid:23654287 |
| Jurkiewicz P et al. | Headgroup hydration and mobility of DOTAP/DOPC bilayers: a fluorescence solvent relaxation study. | 2006 | Langmuir | pmid:17014112 |
| Przybylo M et al. | Lipid diffusion in giant unilamellar vesicles is more than 2 times faster than in supported phospholipid bilayers under identical conditions. | 2006 | Langmuir | pmid:17042516 |
| Gao J et al. | Aromaticity/Bulkiness of Surface Ligands to Promote the Interaction of Anionic Amphiphilic Gold Nanoparticles with Lipid Bilayers. | 2016 | Langmuir | pmid:26794292 |
| Galimzyanov TR et al. | Line Activity of Ganglioside GM1 Regulates the Raft Size Distribution in a Cholesterol-Dependent Manner. | 2017 | Langmuir | pmid:28324651 |
| Achilles A et al. | Self-Assembly of X-Shaped Bolapolyphiles in Lipid Membranes: Solid-State NMR Investigations. | 2016 | Langmuir | pmid:26735449 |
| Suga K et al. | Preferential Adsorption of l-Histidine onto DOPC/Sphingomyelin/3β-[N-(N',N'-dimethylaminoethane)carbamoyl]cholesterol Liposomes in the Presence of Chiral Organic Acids. | 2017 | Langmuir | pmid:28272888 |
| Kataoka-Hamai C et al. | Binding of Lipopolysaccharide and Cholesterol-Modified Gelatin on Supported Lipid Bilayers: Effect of Bilayer Area Confinement and Bilayer Edge Tension. | 2016 | Langmuir | pmid:26735125 |
| Schwierz N et al. | Mechanism of Reversible Peptide-Bilayer Attachment: Combined Simulation and Experimental Single-Molecule Study. | 2016 | Langmuir | pmid:26717083 |
| Chen Y et al. | Interactions of Cationic/Anionic Mixed Surfactant Aggregates with Phospholipid Vesicles and Their Skin Penetration Ability. | 2017 | Langmuir | pmid:28013540 |
| Vermathen M et al. | pH-dependent distribution of chlorin e6 derivatives across phospholipid bilayers probed by NMR spectroscopy. | 2010 | Langmuir | pmid:20420428 |
| Rossetti FF et al. | Asymmetric distribution of phosphatidyl serine in supported phospholipid bilayers on titanium dioxide. | 2006 | Langmuir | pmid:16584212 |
| Richter RP et al. | Formation of solid-supported lipid bilayers: an integrated view. | 2006 | Langmuir | pmid:16584220 |
| Caracciolo G et al. | One-dimensional thermotropic dilatation area of lipid headgroups within lamellar lipid/DNA complexes. | 2006 | Langmuir | pmid:16618174 |
| Kent B et al. | Direct Comparison of Disaccharide Interaction with Lipid Membranes at Reduced Hydrations. | 2015 | Langmuir | pmid:26225718 |
| Folgering JH et al. | Lipid-mediated light activation of a mechanosensitive channel of large conductance. | 2004 | Langmuir | pmid:15301476 |
| Morandat S and El Kirat K | Membrane resistance to Triton X-100 explored by real-time atomic force microscopy. | 2006 | Langmuir | pmid:16768509 |
| Tabaei SR et al. | Solvent-assisted lipid self-assembly at hydrophilic surfaces: factors influencing the formation of supported membranes. | 2015 | Langmuir | pmid:25679066 |
| Carravilla P et al. | Two-photon Laurdan studies of the ternary lipid mixture DOPC:SM:cholesterol reveal a single liquid phase at sphingomyelin:cholesterol ratios lower than 1. | 2015 | Langmuir | pmid:25658036 |
| Inaoka Y and Yamazaki M | Vesicle fission of giant unilamellar vesicles of liquid-ordered-phase membranes induced by amphiphiles with a single long hydrocarbon chain. | 2007 | Langmuir | pmid:17209626 |
| Morandat S and El Kirat K | Real-time atomic force microscopy reveals cytochrome c-induced alterations in neutral lipid bilayers. | 2007 | Langmuir | pmid:17887784 |
| Kucerka N et al. | Curvature effect on the structure of phospholipid bilayers. | 2007 | Langmuir | pmid:17241048 |
| Oh E et al. | Contribution of temperature to deformation of adsorbed vesicles studied by nanoplasmonic biosensing. | 2015 | Langmuir | pmid:25531903 |
| DeWitt BN and Dunn RC | Interaction of cholesterol in ternary lipid mixtures investigated using single-molecule fluorescence. | 2015 | Langmuir | pmid:25531175 |
| Pabst G et al. | Entropy-driven softening of fluid lipid bilayers by alamethicin. | 2007 | Langmuir | pmid:17939689 |
| Lapinski MM et al. | Comparison of liposomes formed by sonication and extrusion: rotational and translational diffusion of an embedded chromophore. | 2007 | Langmuir | pmid:17939695 |
| Giocondi MC et al. | Remodeling of ordered membrane domains by GPI-anchored intestinal alkaline phosphatase. | 2007 | Langmuir | pmid:17661499 |
| Hirano A et al. | One-dimensional protein-based nanoparticles induce lipid bilayer disruption: carbon nanotube conjugates and amyloid fibrils. | 2010 | Langmuir | pmid:20964299 |
| Uppamoochikkal P et al. | Orientation of tie-lines in the phase diagram of DOPC/DPPC/cholesterol model biomembranes. | 2010 | Langmuir | pmid:20968281 |
| Filippov AV et al. | Effect of curcumin on lateral diffusion of phosphatidylcholines in saturated and unsaturated bilayers. | 2014 | Langmuir | pmid:25157681 |
| Zhang S et al. | Freezing or wrapping: the role of particle size in the mechanism of nanoparticle-biomembrane interaction. | 2012 | Langmuir | pmid:22717012 |
| Suga K and Umakoshi H | Detection of nanosized ordered domains in DOPC/DPPC and DOPC/Ch binary lipid mixture systems of large unilamellar vesicles using a TEMPO quenching method. | 2013 | Langmuir | pmid:23506052 |
| Nordlund G et al. | Formation of supported lipid bilayers on silica particles studied using flow cytometry. | 2009 | Langmuir | pmid:19265407 |
| Krishnaswamy R et al. | Aggregation of a peptide antibiotic alamethicin at the air-water interface and its influence on the viscoelasticity of phospholipid monolayers. | 2008 | Langmuir | pmid:18823083 |
| Zidovska A et al. | Block liposomes from curvature-stabilizing lipids: connected nanotubes, -rods, or -spheres. | 2009 | Langmuir | pmid:18834165 |
| Popa R et al. | Entrance effects at nanopores of nanocapsules functionalized with poly(ethylene glycol) and their flow through nanochannels. | 2008 | Langmuir | pmid:18950201 |
| Fried ES et al. | Biodegradable, Tethered Lipid Bilayer-Microsphere Systems with Membrane-Integrated α-Helical Peptide Anchors. | 2016 | Langmuir | pmid:26972467 |
| Richter RP et al. | On the effect of the solid support on the interleaflet distribution of lipids in supported lipid bilayers. | 2005 | Langmuir | pmid:15620318 |
| Orosz KS et al. | Photopolymerization of Dienoyl Lipids Creates Planar Supported Poly(lipid) Membranes with Retained Fluidity. | 2016 | Langmuir | pmid:26794208 |
| Brown AC et al. | Measuring raft size as a function of membrane composition in PC-based systems: Part 1--binary systems. | 2007 | Langmuir | pmid:17887778 |
| Brown AC et al. | Measuring raft size as a function of membrane composition in PC-based systems: Part II--ternary systems. | 2007 | Langmuir | pmid:17887779 |
| Gillams RJ et al. | Formation of inverse topology lyotropic phases in dioleoylphosphatidylcholine/oleic acid and dioleoylphosphatidylethanolamine/oleic acid binary mixtures. | 2014 | Langmuir | pmid:24605989 |
| Buboltz JT et al. | High-resolution mapping of phase behavior in a ternary lipid mixture: do lipid-raft phase boundaries depend on the sample preparation procedure? | 2007 | Langmuir | pmid:17949025 |
| Hochrein MB et al. | Structure and mobility of lipid membranes on a thermoplastic substrate. | 2006 | Langmuir | pmid:16401100 |
| Blanchette CD et al. | Using nucleation rates to determine the interfacial line tension of symmetric and asymmetric lipid bilayer domains. | 2007 | Langmuir | pmid:17451264 |
| Ghosh SK et al. | Structure and Volta potential of lipid multilayers: effect of X-ray irradiation. | 2013 | Langmuir | pmid:23231362 |
| Barriga HM et al. | Buffer-induced swelling and vesicle budding in binary lipid mixtures of dioleoylphosphatidylcholine:dioleoylphosphatidylethanolamine and dioleoylphosphatidylcholine:lysophosphatidylcholine using small-angle X-ray scattering and ³¹P static NMR. | 2015 | Langmuir | pmid:25738977 |
| Pandit SA et al. | Cholesterol packing around lipids with saturated and unsaturated chains: a simulation study. | 2008 | Langmuir | pmid:18517226 |
| Liu C and Faller R | Conformational, dynamical. and tensional study of tethered bilayer lipid membranes in coarse-grained molecular simulations. | 2012 | Langmuir | pmid:23092246 |
| Hamada T et al. | Reversible photoswitching in a cell-sized vesicle. | 2005 | Langmuir | pmid:16089361 |
| Protopapa E et al. | Interaction of self-assembling beta-sheet peptides with phospholipid monolayers: the role of aggregation state, polarity, charge and applied field. | 2009 | Langmuir | pmid:19437790 |
| Zhang N et al. | Partition of Glutamic Acid-Based Single-Chain and Gemini Amphiphiles into Phospholipid Membranes. | 2018 | Langmuir | pmid:30350992 |
| Yasuda T et al. | Nanosized Phase Segregation of Sphingomyelin and Dihydrosphigomyelin in Unsaturated Phosphatidylcholine Binary Membranes without Cholesterol. | 2018 | Langmuir | pmid:30350701 |
| Liu X | Interactions of Silver Nanoparticles Formed in Situ on AFM Tips with Supported Lipid Bilayers. | 2018 | Langmuir | pmid:30109936 |
| Melby ES et al. | Peripheral Membrane Proteins Facilitate Nanoparticle Binding at Lipid Bilayer Interfaces. | 2018 | Langmuir | pmid:30102857 |
| De Oliveira MC et al. | Improvement of in vivo stability of phosphodiester oligonucleotide using anionic liposomes in mice. | 2000 | Life Sci. | pmid:10983856 |
| Lin JT et al. | Biosynthesis of triacylglycerols containing ricinoleate in castor microsomes using 1-acyl-2-oleoyl-sn-glycero-3-phosphocholine as the substrate of oleoyl-12-hydroxylase. | 1998 | Lipids | pmid:9470174 |
| Rouet-Mayer MA et al. | Critical analysis of phospholipid hydrolyzing activities in ripening tomato fruits. Study by spectrofluorimetry and high-performance liquid chromatography. | 1995 | Lipids | pmid:7475990 |
| Sleight RG and Dao HN | Synergistic activation of CTP:phosphocholine cytidylyltransferase by phosphatidylethanolamine and oleic acid. | 1990 | Lipids | pmid:2158609 |
| Van Bambeke F et al. | Biophysical studies and intracellular destabilization of pH-sensitive liposomes. | 2000 | Lipids | pmid:10757553 |
| Pierrat P et al. | DOPC-Detergent Conjugates: Fusogenic Carriers for Improved In Vitro and In Vivo Gene Delivery. | 2016 | Macromol Biosci | pmid:26990218 |
| Orädd G and Lindblom G | Lateral diffusion studied by pulsed field gradient NMR on oriented lipid membranes. | 2004 | Magn Reson Chem | pmid:14745791 |
| GarcÃa-Linares S et al. | The effect of cholesterol on the long-range network of interactions established among sea anemone Sticholysin II residues at the water-membrane interface. | 2015 | Mar Drugs | pmid:25815890 |
| Han WB et al. | Molecular dynamics simulation of interlayer water embedded in phospholipid bilayer. | 2014 | Mater Sci Eng C Mater Biol Appl | pmid:24433886 |
| Protopapa E et al. | Electrochemical screening of self-assembling beta-sheet peptides using supported phospholipid monolayers. | 2006 | Med Eng Phys | pmid:16807052 |
| Tsuchiya M et al. | Antioxidant activity of alpha-tocopherol, beta-carotene, and ubiquinol in membranes: cis-parinaric acid-incorporated liposomes. | 1994 | Meth. Enzymol. | pmid:7808309 |
| Marcocci L et al. | Antioxidant activity of nitecapone and its analog OR-1246: effect of structural modification on antioxidant action. | 1994 | Meth. Enzymol. | pmid:7808329 |
| Tsuchiya M et al. | Antioxidant radical-scavenging activity of carotenoids and retinoids compared to alpha-tocopherol. | 1992 | Meth. Enzymol. | pmid:1435314 |
| Siwak DR et al. | Liposomal antisense oligonucleotides for cancer therapy. | 2004 | Meth. Enzymol. | pmid:15172168 |
| Hostetler KY and Gardner MF | Purification of rat kidney lysosomal phospholipase A1. | 1991 | Meth. Enzymol. | pmid:2051928 |
| Yoshikami S and Nöll GN | Technique for introducing retinol analogs into the isolated retina. | 1982 | Meth. Enzymol. | pmid:7098891 |
| Shayman JA and Abe A | 1-O-acylceramide synthase. | 2000 | Meth. Enzymol. | pmid:10563315 |
| Zidovska A et al. | Block liposomes vesicles of charged lipids with distinctly shaped nanoscale sphere-, pear-, tube-, or rod-segments. | 2009 | Meth. Enzymol. | pmid:19913164 |
| Drachmann ND and Olesen C | Lipid Exchange by Ultracentrifugation. | 2016 | Methods Mol. Biol. | pmid:26695050 |
| Yesylevskyy SO and Demchenko AP | Cholesterol behavior in asymmetric lipid bilayers: insights from molecular dynamics simulations. | 2015 | Methods Mol. Biol. | pmid:25331142 |
| Hu PC and Malmstadt N | Asymmetric giant lipid vesicle fabrication. | 2015 | Methods Mol. Biol. | pmid:25331129 |
| Lee OS and Schatz GC | Computational simulations of the interaction of lipid membranes with DNA-functionalized gold nanoparticles. | 2011 | Methods Mol. Biol. | pmid:21424456 |
| Bacia K and Schwille P | Fluorescence correlation spectroscopy. | 2007 | Methods Mol. Biol. | pmid:18214375 |
| Orädd G and Lindblom G | Lateral diffusion coefficients of raft lipids from pulsed field gradient NMR. | 2007 | Methods Mol. Biol. | pmid:18214378 |
| Salamon Z et al. | Plasmon-waveguide resonance spectroscopy studies of lateral segregation in solid-supported proteolipid bilayers. | 2007 | Methods Mol. Biol. | pmid:18214380 |
| McIntosh TJ | X-ray diffraction to determine the thickness of raft and nonraft bilayers. | 2007 | Methods Mol. Biol. | pmid:18214383 |
| Pencer J et al. | Small-angle neutron scattering to detect rafts and lipid domains. | 2007 | Methods Mol. Biol. | pmid:18214384 |
| Burns AR | Atomic force microscopy of lipid domains in supported model membranes. | 2007 | Methods Mol. Biol. | pmid:18214386 |
| Pezzoli D et al. | Characterization and Investigation of Redox-Sensitive Liposomes for Gene Delivery. | 2016 | Methods Mol. Biol. | pmid:27436322 |
| Myers RL and Chiu IM | Single primer-mediated polymerase chain reaction. | 1994 | Methods Mol. Biol. | pmid:7522831 |
| Mangala LS et al. | Liposomal siRNA for ovarian cancer. | 2009 | Methods Mol. Biol. | pmid:19495686 |
| Zhang J et al. | Lipid peroxidation inhibition capacity assay for antioxidants based on liposomal membranes. | 2006 | Mol Nutr Food Res | pmid:16835871 |
| Riley DE and Krieger JN | Rapid and practical DNA isolation from Trichomonas vaginalis and other nuclease-rich protozoa. | 1992 | Mol. Biochem. Parasitol. | pmid:1565132 |
| Wagner MJ et al. | Preclinical Mammalian Safety Studies of EPHARNA (DOPC Nanoliposomal EphA2-Targeted siRNA). | 2017 | Mol. Cancer Ther. | pmid:28265009 |
| Smith E et al. | Kinetic regulation of the binding of prothrombin to phospholipid membranes. | 2013 | Mol. Cell. Biochem. | pmid:23812842 |
| Ghosh B et al. | Solubilization, purification, and reconstitution of alpha 2 beta 1 isozyme of Na+/K+ -ATPase from caveolae of pulmonary smooth muscle plasma membrane: comparative studies with DHPC, C12E8, and Triton X-100. | 2009 | Mol. Cell. Biochem. | pmid:19101784 |
| Grasso P et al. | Reconstitution of hormone-responsive detergent-solubilized follicle stimulating hormone receptors into liposomes. | 1988 | Mol. Endocrinol. | pmid:3138532 |
| Bradshaw JP et al. | A combined X-ray and neutron diffraction study of selectively deuterated melittin in phospholipid bilayers: effect of pH. | 1994 Apr-Jun | Mol. Membr. Biol. | pmid:7920866 |
| Garner AE et al. | Sphingomyelin chain length influences the distribution of GPI-anchored proteins in rafts in supported lipid bilayers. | 2007 May-Jun | Mol. Membr. Biol. | pmid:17520480 |
| Wesołowska O et al. | Direct visualization of phase separation induced by phenothiazine-type antipsychotic drugs in model lipid membranes. | 2011 | Mol. Membr. Biol. | pmid:21190429 |
| Maggio B | Control by ganglioside GD1a of phospholipase A2 activity through modulation of the lamellar-hexagonal (HII) phase transition. | 1996 Apr-Jun | Mol. Membr. Biol. | pmid:8839455 |