1,2-Dioleoyl-sn-Glycero-3-Phosphocholine is a lipid of Glycerophospholipids (GP) class. 1,2-dioleoyl-sn-glycero-3-phosphocholine is associated with abnormalities such as Exanthema, Renal tubular disorder, Nodule, Gigantism and Mycoses. The involved functions are known as Lysis, Encapsulation, Process, Uptake and Flow or discharge. 1,2-dioleoyl-sn-glycero-3-phosphocholine often locates in Cytoplasmic matrix, Endosomes, soluble, Endoplasmic Reticulum and Membrane. The associated genes with 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine are P4HTM gene, synthetic peptide, BCAR1 gene, PCNA gene and CNTNAP1 gene. The related lipids are Liposomes, 1,2-oleoylphosphatidylcholine, 1,2-distearoylphosphatidylethanolamine, Butanols and Cardiolipins. The related experimental models are Mouse Model and Xenograft Model.
To understand associated biological information of 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
1,2-Dioleoyl-sn-Glycero-3-Phosphocholine is suspected in Gigantism, Nodule, protrusion, DERMATITIS HERPETIFORMIS, FAMILIAL, Exanthema, Renal tubular disorder and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Celiac Disease | D002446 | 16 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Hemolysis | D006461 | 131 associated lipids |
| Neuroblastoma | D009447 | 66 associated lipids |
| Niemann-Pick Diseases | D009542 | 25 associated lipids |
| Ovarian Neoplasms | D010051 | 10 associated lipids |
| Respiratory Syncytial Virus Infections | D018357 | 10 associated lipids |
| Atherosclerosis | D050197 | 85 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
| Lipid concept | Cross reference | Weighted score | Related literatures |
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| Gene | Cross reference | Weighted score | Related literatures |
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Xenograft Model are used in the study 'Therapeutic targeting of PELP1 prevents ovarian cancer growth and metastasis.' (Chakravarty D et al., 2011).
Mouse Model are used in the study 'Therapeutic EphA2 gene targeting in vivo using neutral liposomal small interfering RNA delivery.' (Landen CN et al., 2005).
| Model | Cross reference | Weighted score | Related literatures |
|---|
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Ackerman DG and Feigenson GW | Lipid bilayers: clusters, domains and phases. | 2015 | Essays Biochem. | pmid:25658342 |
| Smirnova YG and Müller M | Calculation of membrane bending rigidity using field-theoretic umbrella sampling. | 2015 | J Chem Phys | pmid:26723640 |
| Moerkerke S et al. | Selective Recognition of Phosphatidylcholine Lipids by a Biomimetic Calix[6]tube Receptor. | 2015 | J. Org. Chem. | pmid:26258943 |
| Kent B et al. | Direct Comparison of Disaccharide Interaction with Lipid Membranes at Reduced Hydrations. | 2015 | Langmuir | pmid:26225718 |
| Yilmaz N and Kobayashi T | Visualization of Lipid Membrane Reorganization Induced by a Pore-Forming Toxin Using High-Speed Atomic Force Microscopy. | 2015 | ACS Nano | pmid:26222645 |
| Becucci L and Guidelli R | Can gramicidin ion channel affect the dipole potential of neighboring phospholipid headgroups? | 2015 | Bioelectrochemistry | pmid:26190793 |
| Navrátilová V et al. | Effect of cholesterol on the structure of membrane-attached cytochrome P450 3A4. | 2015 | J Chem Inf Model | pmid:25654496 |
| Oude Blenke E et al. | Liposome functionalization with copper-free "click chemistry". | 2015 | J Control Release | pmid:25626085 |
| Larsen JB et al. | Membrane curvature enables N-Ras lipid anchor sorting to liquid-ordered membrane phases. | 2015 | Nat. Chem. Biol. | pmid:25622090 |
| Moskovitz Y and Yang H | Modelling of noble anaesthetic gases and high hydrostatic pressure effects in lipid bilayers. | 2015 | Soft Matter | pmid:25612767 |
| Pezeshkian W et al. | The effects of globotriaosylceramide tail saturation level on bilayer phases. | 2015 | Soft Matter | pmid:25575293 |
| Karami L and Jalili S | Effects of cholesterol concentration on the interaction of cytarabine with lipid membranes: a molecular dynamics simulation study. | 2015 | J. Biomol. Struct. Dyn. | pmid:25068451 |
| Shimokawa N et al. | Physical properties of the hybrid lipid POPC on micrometer-sized domains in mixed lipid membranes. | 2015 | Phys Chem Chem Phys | pmid:26214181 |
| Balleza D et al. | Effects of neurosteroids on a model membrane including cholesterol: A micropipette aspiration study. | 2015 | Biochim. Biophys. Acta | pmid:25660752 |
| Sacchi M et al. | Effect of neurosteroids on a model lipid bilayer including cholesterol: An Atomic Force Microscopy study. | 2015 | Biochim. Biophys. Acta | pmid:25620773 |
| Barnoud J et al. | C₆₀ fullerene promotes lung monolayer collapse. | 2015 | J R Soc Interface | pmid:25589571 |
| Evans KO et al. | Hydroxytyrosol and tyrosol esters partitioning into, location within, and effect on DOPC liposome bilayer behavior. | 2015 | Biochim. Biophys. Acta | pmid:25687972 |
| Quazi F and Molday RS | ATP-binding cassette transporter ABCA4 and chemical isomerization protect photoreceptor cells from the toxic accumulation of excess 11-cis-retinal. | 2014 | Proc. Natl. Acad. Sci. U.S.A. | pmid:24707049 |
| Stephan M et al. | Combining reflectometry and fluorescence microscopy: an assay for the investigation of leakage processes across lipid membranes. | 2014 | Anal. Chem. | pmid:24377291 |
| Islam MZ et al. | Entry of cell-penetrating peptide transportan 10 into a single vesicle by translocating across lipid membrane and its induced pores. | 2014 | Biochemistry | pmid:24397335 |
| Chen D and Santore MM | Large effect of membrane tension on the fluid-solid phase transitions of two-component phosphatidylcholine vesicles. | 2014 | Proc. Natl. Acad. Sci. U.S.A. | pmid:24344297 |
| Mohamadi S et al. | Electrochemical screening of biomembrane-active compounds in water. | 2014 | Anal. Chim. Acta | pmid:24528664 |
| Fraenza CC et al. | The effect of cholesterol on membrane dynamics on different timescales in lipid bilayers from fast field-cycling NMR relaxometry studies of unilamellar vesicles. | 2014 | Chemphyschem | pmid:24482248 |
| Dékány Fraňová M et al. | Can pyrene probes be used to measure lateral pressure profiles of lipid membranes? Perspective through atomistic simulations. | 2014 | Biochim. Biophys. Acta | pmid:24508757 |
| Kinoshita M et al. | Coexistence of two liquid crystalline phases in dihydrosphingomyelin and dioleoylphosphatidylcholine binary mixtures. | 2014 | Biochim. Biophys. Acta | pmid:24468063 |
| Maté SM et al. | Boundary region between coexisting lipid phases as initial binding sites for Escherichia coli alpha-hemolysin: a real-time study. | 2014 | Biochim. Biophys. Acta | pmid:24613790 |
| Rokitskaya TI et al. | Unsaturated lipids protect the integral membrane peptide gramicidin A from singlet oxygen. | 2014 | FEBS Lett. | pmid:24613917 |
| Han WB et al. | Molecular dynamics simulation of interlayer water embedded in phospholipid bilayer. | 2014 | Mater Sci Eng C Mater Biol Appl | pmid:24433886 |
| Costa PJ et al. | Interaction of a calix[4]arene derivative with a DOPC bilayer: biomolecular simulations towards chloride transport. | 2014 | Biochim. Biophys. Acta | pmid:24316169 |
| Leyrat C et al. | Structure and self-assembly of the calcium binding matrix protein of human metapneumovirus. | 2014 | Structure | pmid:24316400 |
| Walsh P et al. | The mechanism of membrane disruption by cytotoxic amyloid oligomers formed by prion protein(106-126) is dependent on bilayer composition. | 2014 | J. Biol. Chem. | pmid:24554723 |
| Tada DB et al. | Effect of lipid coating on the interaction between silica nanoparticles and membranes. | 2014 | J Biomed Nanotechnol | pmid:24730247 |
| BeliÄka M et al. | Molecular and component volumes of N,N-dimethyl-N-alkylamine N-oxides in DOPC bilayers. | 2014 | Chem. Phys. Lipids | pmid:24631067 |
| Jiang J et al. | Designing inhibitors of cytochrome c/cardiolipin peroxidase complexes: mitochondria-targeted imidazole-substituted fatty acids. | 2014 | Free Radic. Biol. Med. | pmid:24631490 |
| Aci-Sèche S et al. | Transmembrane recognition of the semaphorin co-receptors neuropilin 1 and plexin A1: coarse-grained simulations. | 2014 | PLoS ONE | pmid:24858828 |
| Jablin MS et al. | Experimental support for tilt-dependent theory of biomembrane mechanics. | 2014 | Phys. Rev. Lett. | pmid:25541806 |
| Pokorna S et al. | Does fluoride disrupt hydrogen bond network in cationic lipid bilayer? Time-dependent fluorescence shift of Laurdan and molecular dynamics simulations. | 2014 | J Chem Phys | pmid:25494787 |
| Jeong DW et al. | Fluorescence recovery after merging a surfactant-covered droplet: a novel technique to measure the diffusion of phospholipid monolayers at fluid/fluid interfaces. | 2014 | Langmuir | pmid:25422050 |
| Miles P and Frankel D | Lipid directed assembly of the HIV capsid protein. | 2014 | Soft Matter | pmid:25354471 |
| Paloncýová M et al. | Rationalization of reduced penetration of drugs through ceramide gel phase membrane. | 2014 | Langmuir | pmid:25354090 |
| Rozmanov D et al. | Density based visualization for molecular simulation. | 2014 | Faraday Discuss. | pmid:25341200 |
| Shatursky OY et al. | Anion carrier formation by calix[4]arene-bis-hydroxymethylphosphonic acid in bilayer membranes. | 2014 | Org. Biomol. Chem. | pmid:25335911 |
| Goliaei A et al. | Local pressure changes in lipid bilayers due to adsorption of melittin and magainin-h2 antimicrobial peptides: results from computer simulations. | 2014 | J Phys Chem B | pmid:25299589 |
| Michel R et al. | Internalization of silica nanoparticles into fluid liposomes: formation of interesting hybrid colloids. | 2014 | Angew. Chem. Int. Ed. Engl. | pmid:25257684 |
| Przybyło M et al. | Effect of monovalent anions on water transmembrane transport. | 2014 | J Phys Chem B | pmid:25203862 |
| Liland NS et al. | Polyaromatic hydrocarbons do not disturb liquid-liquid phase coexistence, but increase the fluidity of model membranes. | 2014 | Chem. Phys. Lipids | pmid:25181555 |
| Van Lehn RC et al. | Lipid tail protrusions mediate the insertion of nanoparticles into model cell membranes. | 2014 | Nat Commun | pmid:25042518 |
| Ringhieri P et al. | Target selective micelles for bombesin receptors incorporating Au(III)-dithiocarbamato complexes. | 2014 | Int J Pharm | pmid:25014371 |
| Bog U et al. | Large-scale parallel surface functionalization of goblet-type whispering gallery mode microcavity arrays for biosensing applications. | 2014 | Small | pmid:24990526 |
| Klacsová M et al. | Phase behavior of the DOPE + DOPC + alkanol system. | 2014 | Soft Matter | pmid:24980804 |
| Donohue MP et al. | The N-terminal of annexin A1 as a secondary membrane binding site: a molecular dynamics study. | 2014 | Proteins | pmid:24913225 |
| Balk S et al. | Terbium(III)-cholate functionalized vesicles as luminescent indicators for the enzymatic conversion of dihydroxynaphthalene diesters. | 2014 | Chem. Commun. (Camb.) | pmid:24910019 |
| Gordillo GJ et al. | Interactions of gold nanoparticles with a phospholipid monolayer membrane on mercury. | 2014 | ACS Nano | pmid:24878256 |
| Wang F and Liu J | Liposome supported metal oxide nanoparticles: interaction mechanism, light controlled content release, and intracellular delivery. | 2014 | Small | pmid:24861966 |
| Hoffmann I et al. | Softening of phospholipid membranes by the adhesion of silica nanoparticles--as seen by neutron spin-echo (NSE). | 2014 | Nanoscale | pmid:24838980 |
| Guyomarc'h F et al. | Milk sphingomyelin domains in biomimetic membranes and the role of cholesterol: morphology and nanomechanical properties investigated using AFM and force spectroscopy. | 2014 | Langmuir | pmid:24835749 |
| van der Meulen SA et al. | Quartz crystal microbalance with dissipation monitoring and spectroscopic ellipsometry measurements of the phospholipid bilayer anchoring stability and kinetics of hydrophobically modified DNA oligonucleotides. | 2014 | Langmuir | pmid:24823835 |
| Yoon J et al. | Nanoparticles of conjugated polymers prepared from phase-separated films of phospholipids and polymers for biomedical applications. | 2014 | Adv. Mater. Weinheim | pmid:24789764 |
| Kogan M et al. | Shear-induced membrane fusion in viscous solutions. | 2014 | Langmuir | pmid:24758573 |
| Migas UM et al. | Adding glycolipid functionality to model membranes--phase behaviour of a synthetic glycolipid in a phospholipid membrane. | 2014 | Soft Matter | pmid:24733306 |
| Poznik M and König B | Cooperative hydrolysis of aryl esters on functionalized membrane surfaces and in micellar solutions. | 2014 | Org. Biomol. Chem. | pmid:24722623 |
| Kawamoto S and Shinoda W | Free energy analysis along the stalk mechanism of membrane fusion. | 2014 | Soft Matter | pmid:24695575 |
| BeliÄka M et al. | Effects of N,N-dimethyl-N-alkylamine-N-oxides on DOPC bilayers in unilamellar vesicles: small-angle neutron scattering study. | 2014 | Eur. Biophys. J. | pmid:24687686 |
| Nadvorny D et al. | Anionic form of usnic acid promotes lamellar to nonlamellar transition in DPPC and DOPC membranes. | 2014 | J Phys Chem B | pmid:24655129 |
| Becucci L et al. | Dermcidin, an anionic antimicrobial peptide: influence of lipid charge, pH and Zn2+ on its interaction with a biomimetic membrane. | 2014 | Soft Matter | pmid:24652391 |
| Vakurov A et al. | Direct characterization of fluid lipid assemblies on mercury in electric fields. | 2014 | ACS Nano | pmid:24625246 |
| Yoshida K et al. | Deformation of lipid membranes containing photoresponsive molecules in response to ultraviolet light. | 2014 | J Phys Chem B | pmid:24625027 |
| Setiawan I and Blanchard GJ | Ethanol-induced perturbations to planar lipid bilayer structures. | 2014 | J Phys Chem B | pmid:24372563 |
| Nagarajan A et al. | The effects of flanking sequences in the interaction of polyglutamine peptides with a membrane bilayer. | 2014 | J Phys Chem B | pmid:24354677 |
| Fischer NO et al. | Evaluation of nanolipoprotein particles (NLPs) as an in vivo delivery platform. | 2014 | PLoS ONE | pmid:24675794 |
| Van Lehn RC and Alexander-Katz A | Membrane-embedded nanoparticles induce lipid rearrangements similar to those exhibited by biological membrane proteins. | 2014 | J Phys Chem B | pmid:25347475 |
| Grosse W et al. | Structure-based engineering of a minimal porin reveals loop-independent channel closure. | 2014 | Biochemistry | pmid:24988371 |
| Mertins O et al. | Physical damage on giant vesicles membrane as a result of methylene blue photoirradiation. | 2014 | Biophys. J. | pmid:24411248 |
| Gillams RJ et al. | Formation of inverse topology lyotropic phases in dioleoylphosphatidylcholine/oleic acid and dioleoylphosphatidylethanolamine/oleic acid binary mixtures. | 2014 | Langmuir | pmid:24605989 |
| Souza AC et al. | Development and characterization of multilamellar liposomes containing pyridostigmine. | 2014 | Pharm Dev Technol | pmid:23682846 |
| Vargas JN et al. | Fast membrane hemifusion via dewetting between lipid bilayers. | 2014 | Soft Matter | pmid:25330351 |
| Kardash ME and Dzuba SA | Communication: Orientational self-ordering of spin-labeled cholesterol analogs in lipid bilayers in diluted conditions. | 2014 | J Chem Phys | pmid:25481121 |
| Sublimi Saponetti M et al. | Aggregation of Aß(25-35) on DOPC and DOPC/DHA bilayers: an atomic force microscopy study. | 2014 | PLoS ONE | pmid:25551704 |
| Koshy SS et al. | Hydrogen exchange differences between chemoreceptor signaling complexes localize to functionally important subdomains. | 2014 | Biochemistry | pmid:25420045 |
| Du Z et al. | The role of the helper lipid on the DNA transfection efficiency of lipopolyplex formulations. | 2014 | Sci Rep | pmid:25407686 |
| Yanagisawa M et al. | Multiple patterns of polymer gels in microspheres due to the interplay among phase separation, wetting, and gelation. | 2014 | Proc. Natl. Acad. Sci. U.S.A. | pmid:25349417 |
| Sly KL and Conboy JC | Determination of multivalent protein-ligand binding kinetics by second-harmonic correlation spectroscopy. | 2014 | Anal. Chem. | pmid:25314127 |
| Payton NM et al. | Long-term storage of lyophilized liposomal formulations. | 2014 | J Pharm Sci | pmid:25308534 |
| Chakraborty H et al. | pH Alters PEG-mediated fusion of phosphatidylethanolamine-containing vesicles. | 2014 | Biophys. J. | pmid:25229141 |
| Nelson SR et al. | Motor coupling through lipid membranes enhances transport velocities for ensembles of myosin Va. | 2014 | Proc. Natl. Acad. Sci. U.S.A. | pmid:25201964 |
| Baoukina S et al. | The mechanism of collapse of heterogeneous lipid monolayers. | 2014 | Biophys. J. | pmid:25185549 |
| Sletten A et al. | Surface features of the lipid droplet mediate perilipin 2 localization. | 2014 | Biochem. Biophys. Res. Commun. | pmid:25172666 |
| Pieffet G et al. | Exploring the local elastic properties of bilayer membranes using molecular dynamics simulations. | 2014 | J Phys Chem B | pmid:25325715 |
| Kacprzyk-Stokowiec A et al. | Crucial role of perfringolysin O D1 domain in orchestrating structural transitions leading to membrane-perforating pores: a hydrogen-deuterium exchange study. | 2014 | J. Biol. Chem. | pmid:25164812 |
| Banga RJ et al. | Liposomal spherical nucleic acids. | 2014 | J. Am. Chem. Soc. | pmid:24983505 |
| Hughes ZE and Mancera RL | Molecular mechanism of the synergistic effects of vitrification solutions on the stability of phospholipid bilayers. | 2014 | Biophys. J. | pmid:24940779 |
| Vanni S et al. | A sub-nanometre view of how membrane curvature and composition modulate lipid packing and protein recruitment. | 2014 | Nat Commun | pmid:25222832 |
| Maté S et al. | N-nervonoylsphingomyelin (C24:1) prevents lateral heterogeneity in cholesterol-containing membranes. | 2014 | Biophys. J. | pmid:24940778 |
| Matysik A and Kraut RS | TrackArt: the user friendly interface for single molecule tracking data analysis and simulation applied to complex diffusion in mica supported lipid bilayers. | 2014 | BMC Res Notes | pmid:24885944 |
| Davis JH and Schmidt ML | Critical behaviour in DOPC/DPPC/cholesterol mixtures: static (2)H NMR line shapes near the critical point. | 2014 | Biophys. J. | pmid:24806929 |
| Kalsi S et al. | Shaped apertures in photoresist films enhance the lifetime and mechanical stability of suspended lipid bilayers. | 2014 | Biophys. J. | pmid:24739164 |
| Perrault SD and Shih WM | Virus-inspired membrane encapsulation of DNA nanostructures to achieve in vivo stability. | 2014 | ACS Nano | pmid:24694301 |
| Kent B et al. | Localization of trehalose in partially hydrated DOPC bilayers: insights into cryoprotective mechanisms. | 2014 | J R Soc Interface | pmid:24647907 |
| Silva BF et al. | PEGylated cationic liposome-DNA complexation in brine is pathway-dependent. | 2014 | Biochim. Biophys. Acta | pmid:24060564 |
| Liu Y et al. | Biomembrane disruption by silica-core nanoparticles: effect of surface functional group measured using a tethered bilayer lipid membrane. | 2014 | Biochim. Biophys. Acta | pmid:24060565 |