1,2-Dioleoyl-sn-Glycero-3-Phosphocholine is a lipid of Glycerophospholipids (GP) class. 1,2-dioleoyl-sn-glycero-3-phosphocholine is associated with abnormalities such as Exanthema, Renal tubular disorder, Nodule, Gigantism and Mycoses. The involved functions are known as Lysis, Encapsulation, Process, Uptake and Flow or discharge. 1,2-dioleoyl-sn-glycero-3-phosphocholine often locates in Cytoplasmic matrix, Endosomes, soluble, Endoplasmic Reticulum and Membrane. The associated genes with 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine are P4HTM gene, synthetic peptide, BCAR1 gene, PCNA gene and CNTNAP1 gene. The related lipids are Liposomes, 1,2-oleoylphosphatidylcholine, 1,2-distearoylphosphatidylethanolamine, Butanols and Cardiolipins. The related experimental models are Mouse Model and Xenograft Model.
To understand associated biological information of 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
1,2-Dioleoyl-sn-Glycero-3-Phosphocholine is suspected in Gigantism, Nodule, protrusion, DERMATITIS HERPETIFORMIS, FAMILIAL, Exanthema, Renal tubular disorder and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Celiac Disease | D002446 | 16 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Hemolysis | D006461 | 131 associated lipids |
| Neuroblastoma | D009447 | 66 associated lipids |
| Niemann-Pick Diseases | D009542 | 25 associated lipids |
| Ovarian Neoplasms | D010051 | 10 associated lipids |
| Respiratory Syncytial Virus Infections | D018357 | 10 associated lipids |
| Atherosclerosis | D050197 | 85 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
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| Lipid concept | Cross reference | Weighted score | Related literatures |
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| Gene | Cross reference | Weighted score | Related literatures |
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Xenograft Model are used in the study 'Therapeutic targeting of PELP1 prevents ovarian cancer growth and metastasis.' (Chakravarty D et al., 2011).
Mouse Model are used in the study 'Therapeutic EphA2 gene targeting in vivo using neutral liposomal small interfering RNA delivery.' (Landen CN et al., 2005).
| Model | Cross reference | Weighted score | Related literatures |
|---|
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Esnault C et al. | Another example of enzymatic promiscuity: the polyphosphate kinase of Streptomyces lividans is endowed with phospholipase D activity. | 2017 | Appl. Microbiol. Biotechnol. | pmid:27488682 |
| Moriwaki H et al. | Electrochemical extraction of gold from wastes as nanoparticles stabilized by phospholipids. | 2017 | Waste Manag | pmid:27424309 |
| Breidigan JM et al. | Influence of the membrane environment on cholesterol transfer. | 2017 | J. Lipid Res. | pmid:29046341 |
| Janeczek AA et al. | PEGylated liposomes associate with Wnt3A protein and expand putative stem cells in human bone marrow populations. | 2017 | Nanomedicine (Lond) | pmid:28351228 |
| McDonald C et al. | Structure and function of PspA and Vipp1 N-terminal peptides: Insights into the membrane stress sensing and mitigation. | 2017 | Biochim. Biophys. Acta | pmid:27806910 |
| Wallner J et al. | An approach for liposome immobilization using sterically stabilized micelles (SSMs) as a precursor for bio-layer interferometry-based interaction studies. | 2017 | Colloids Surf B Biointerfaces | pmid:28340485 |
| Worch R et al. | Diffusion of Single-Pass Transmembrane Receptors: From the Plasma Membrane into Giant Liposomes. | 2017 | J. Membr. Biol. | pmid:27826635 |
| Renauld S et al. | Functional reconstitution of cell-free synthesized purified K channels. | 2017 | Biochim. Biophys. Acta | pmid:28888365 |
| Singh MK et al. | Probe-location dependent resonance energy transfer at lipid/water interfaces: comparison between the gel- and fluid-phase of lipid bilayer. | 2017 | Phys Chem Chem Phys | pmid:28726898 |
| Favarin BZ et al. | Effect of the presence of cholesterol in the interfacial microenvironment on the modulation of the alkaline phosphatase activity during in vitro mineralization. | 2017 | Colloids Surf B Biointerfaces | pmid:28472750 |
| Wagner MJ et al. | Preclinical Mammalian Safety Studies of EPHARNA (DOPC Nanoliposomal EphA2-Targeted siRNA). | 2017 | Mol. Cancer Ther. | pmid:28265009 |
| Malyshka D and Schweitzer-Stenner R | Ferrocyanide-Mediated Photoreduction of Ferricytochrome C Utilized to Selectively Probe Non-native Conformations Induced by Binding to Cardiolipin-Containing Liposomes. | 2017 | Chemistry | pmid:27859757 |
| Khan FI et al. | Structure prediction and functional analyses of a thermostable lipase obtained from Shewanella putrefaciens. | 2017 | J. Biomol. Struct. Dyn. | pmid:27366981 |
| Piantanida L et al. | Ions Modulate Stress-Induced Nanotexture in Supported Fluid Lipid Bilayers. | 2017 | Biophys. J. | pmid:28746853 |
| Krishnan P et al. | Hetero-multivalent binding of cholera toxin subunit B with glycolipid mixtures. | 2017 | Colloids Surf B Biointerfaces | pmid:28946063 |
| Xing J et al. | Increasing vaccine production using pulsed ultrasound waves. | 2017 | PLoS ONE | pmid:29176801 |
| Lum K et al. | Exchange of Gramicidin between Lipid Bilayers: Implications for the Mechanism of Channel Formation. | 2017 | Biophys. J. | pmid:29045870 |
| He B et al. | Increased cellular uptake of peptide-modified PEGylated gold nanoparticles. | 2017 | Biochem. Biophys. Res. Commun. | pmid:28993197 |
| Cornell CE et al. | n-Alcohol Length Governs Shift in L-L Mixing Temperatures in Synthetic and Cell-Derived Membranes. | 2017 | Biophys. J. | pmid:28801104 |
| Moniruzzaman M et al. | Entry of a Six-Residue Antimicrobial Peptide Derived from Lactoferricin B into Single Vesicles and Escherichia coli Cells without Damaging their Membranes. | 2017 | Biochemistry | pmid:28752991 |