1,2-Dioleoyl-sn-Glycero-3-Phosphocholine

1,2-Dioleoyl-sn-Glycero-3-Phosphocholine is a lipid of Glycerophospholipids (GP) class. 1,2-dioleoyl-sn-glycero-3-phosphocholine is associated with abnormalities such as Exanthema, Renal tubular disorder, Nodule, Gigantism and Mycoses. The involved functions are known as Lysis, Encapsulation, Process, Uptake and Flow or discharge. 1,2-dioleoyl-sn-glycero-3-phosphocholine often locates in Cytoplasmic matrix, Endosomes, soluble, Endoplasmic Reticulum and Membrane. The associated genes with 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine are P4HTM gene, synthetic peptide, BCAR1 gene, PCNA gene and CNTNAP1 gene. The related lipids are Liposomes, 1,2-oleoylphosphatidylcholine, 1,2-distearoylphosphatidylethanolamine, Butanols and Cardiolipins. The related experimental models are Mouse Model and Xenograft Model.

Cross Reference

Introduction

To understand associated biological information of 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine?

1,2-Dioleoyl-sn-Glycero-3-Phosphocholine is suspected in Gigantism, Nodule, protrusion, DERMATITIS HERPETIFORMIS, FAMILIAL, Exanthema, Renal tubular disorder and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine

MeSH term MeSH ID Detail
Celiac Disease D002446 16 associated lipids
Edema D004487 152 associated lipids
Hemolysis D006461 131 associated lipids
Neuroblastoma D009447 66 associated lipids
Niemann-Pick Diseases D009542 25 associated lipids
Ovarian Neoplasms D010051 10 associated lipids
Respiratory Syncytial Virus Infections D018357 10 associated lipids
Atherosclerosis D050197 85 associated lipids
Total 8

PubChem Associated disorders and diseases

What pathways are associated with 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine?

Xenograft Model

Xenograft Model are used in the study 'Therapeutic targeting of PELP1 prevents ovarian cancer growth and metastasis.' (Chakravarty D et al., 2011).

Mouse Model

Mouse Model are used in the study 'Therapeutic EphA2 gene targeting in vivo using neutral liposomal small interfering RNA delivery.' (Landen CN et al., 2005).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

NCBI Entrez Crosslinks

All references with 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine

Download all related citations
Per page 10 20 50 100 | Total 1807
Authors Title Published Journal PubMed Link
Leventis R et al. Divalent cation induced fusion and lipid lateral segregation in phosphatidylcholine-phosphatidic acid vesicles. 1986 Biochemistry pmid:3801406
Stopar D et al. Local dynamics of the M13 major coat protein in different membrane-mimicking systems. 1996 Biochemistry pmid:8952500
Niu SL et al. Trans fatty acid derived phospholipids show increased membrane cholesterol and reduced receptor activation as compared to their cis analogs. 2005 Biochemistry pmid:15766276
Tatulian SA et al. Uncovering a calcium-regulated membrane-binding mechanism for soybean lipoxygenase-1. 1998 Biochemistry pmid:9799511
Buffy JJ et al. Two-dimensional solid-state NMR reveals two topologies of sarcolipin in oriented lipid bilayers. 2006 Biochemistry pmid:16953579
Curran AR et al. Modulation of folding and assembly of the membrane protein bacteriorhodopsin by intermolecular forces within the lipid bilayer. 1999 Biochemistry pmid:10413507
Willems GM et al. Transient high affinity binding of tissue factor pathway inhibitor-factor Xa complexes to negatively charged phospholipid membranes. 1998 Biochemistry pmid:9521652
Wilschut J et al. Kinetics of Ca2+-induced fusion of cardiolipin-phosphatidylcholine vesicles: correlation between vesicle aggregation, bilayer destabilization, and fusion. 1985 Biochemistry pmid:4063345
Kubo M and Hostetler KY Mechanism of cationic amphiphilic drug inhibition of purified lysosomal phospholipase A1. 1985 Biochemistry pmid:4084534
Caputo GA and London E Position and ionization state of Asp in the core of membrane-inserted alpha helices control both the equilibrium between transmembrane and nontransmembrane helix topography and transmembrane helix positioning. 2004 Biochemistry pmid:15236588
BaÅŸaran N et al. Effect of lipid unsaturation on the binding of native and a mutant form of cytochrome b5 to membranes. 1999 Biochemistry pmid:10563808
Ganchev DN et al. Size and orientation of the lipid II headgroup as revealed by AFM imaging. 2006 Biochemistry pmid:16681392
Abe M et al. Molecular mechanisms for the induction of peroxidase activity of the cytochrome c-cardiolipin complex. 2011 Biochemistry pmid:21877718
van den Brink-van der Laan E et al. Small alcohols destabilize the KcsA tetramer via their effect on the membrane lateral pressure. 2004 Biochemistry pmid:15147177
Wu F et al. Stability of annexin V in ternary complexes with Ca2+ and anionic phospholipids: IR studies of monolayer and bulk phases. 1999 Biochemistry pmid:9888820
Liu F and Chong PL Evidence for a regulatory role of cholesterol superlattices in the hydrolytic activity of secretory phospholipase A2 in lipid membranes. 1999 Biochemistry pmid:10194297
Gomez B and Robinson NC Phospholipase digestion of bound cardiolipin reversibly inactivates bovine cytochrome bc1. 1999 Biochemistry pmid:10413476
Ostroski M et al. Analysis of a novel diacylglycerol kinase from Dictyostelium discoideum: DGKA. 2005 Biochemistry pmid:16042397
Yau WM et al. The preference of tryptophan for membrane interfaces. 1998 Biochemistry pmid:9778346
Subczynski WK et al. Hydrophobic barriers of lipid bilayer membranes formed by reduction of water penetration by alkyl chain unsaturation and cholesterol. 1994 Biochemistry pmid:8011634
Hathcock J et al. Lipid-bound factor Xa regulates tissue factor activity. 2007 Biochemistry pmid:17469850
Alford D et al. Fusion of influenza virus with sialic acid-bearing target membranes. 1994 Biochemistry pmid:8117654
Pinheiro TJ and Watts A Resolution of individual lipids in mixed phospholipid membranes and specific lipid-cytochrome c interactions by magic-angle spinning solid-state phosphorus-31 NMR. 1994 Biochemistry pmid:8117706
Kapralov AA et al. The hierarchy of structural transitions induced in cytochrome c by anionic phospholipids determines its peroxidase activation and selective peroxidation during apoptosis in cells. 2007 Biochemistry pmid:18004876
Pécheur EI et al. Lipid headgroup spacing and peptide penetration, but not peptide oligomerization, modulate peptide-induced fusion. 1999 Biochemistry pmid:9890918
Wang T et al. Nanomechanical recognition of sphingomyelin-rich membrane domains by atomic force microscopy. 2012 Biochemistry pmid:22148674
Srivastava A et al. Soluble phosphatidylserine binds to a single identified site in the C2 domain of human factor Va. 2001 Biochemistry pmid:11444970
Chen SY et al. Quantitation of lateral stress in lipid layer containing nonbilayer phase preferring lipids by frequency-domain fluorescence spectroscopy. 1992 Biochemistry pmid:1567830
Tournois H et al. Gramicidin A induced fusion of large unilamellar dioleoylphosphatidylcholine vesicles and its relation to the induction of type II nonbilayer structures. 1990 Biochemistry pmid:1701325
van de Waart P et al. Interaction of bovine blood clotting factor Va and its subunits with phospholipid vesicles. 1983 Biochemistry pmid:6860639
Patel GJ et al. The periplasmic chaperone Skp facilitates targeting, insertion, and folding of OmpA into lipid membranes with a negative membrane surface potential. 2009 Biochemistry pmid:19780589
Madden TD et al. Lipid requirements for coupled cytochrome oxidase vesicles. 1983 Biochemistry pmid:6303398
Gremlich HU et al. Conformational changes of adrenocorticotropin peptides upon interaction with lipid membranes revealed by infrared attenuated total reflection spectroscopy. 1983 Biochemistry pmid:6313037
Hayashibara M and London E Topography of diphtheria toxin A chain inserted into lipid vesicles. 2005 Biochemistry pmid:15697244
Yang L et al. New phases of phospholipids and implications to the membrane fusion problem. 2003 Biochemistry pmid:12779317
Rasmussen T et al. Properties of the Mechanosensitive Channel MscS Pore Revealed by Tryptophan Scanning Mutagenesis. 2015 Biochemistry pmid:26126964
Clark EH et al. The role of tryptophan residues in an integral membrane protein: diacylglycerol kinase. 2003 Biochemistry pmid:12974643
Tate MW and Gruner SM Temperature dependence of the structural dimensions of the inverted hexagonal (HII) phase of phosphatidylethanolamine-containing membranes. 1989 Biochemistry pmid:2765485
Billy D et al. Inhibition of prothrombinase at macroscopic lipid membranes: competition between antithrombin and prothrombin. 1995 Biochemistry pmid:7577961
Wright CS et al. Crystal structure analysis of phosphatidylcholine-GM2-activator product complexes: evidence for hydrolase activity. 2005 Biochemistry pmid:16216074
Méthot N et al. Structure of both the ligand- and lipid-dependent channel-inactive states of the nicotinic acetylcholine receptor probed by FTIR spectroscopy and hydrogen exchange. 1995 Biochemistry pmid:7578128
Mach H and Middaugh CR Interaction of partially structured states of acidic fibroblast growth factor with phospholipid membranes. 1995 Biochemistry pmid:7543282
Koshy SS et al. Hydrogen exchange differences between chemoreceptor signaling complexes localize to functionally important subdomains. 2014 Biochemistry pmid:25420045
Moniruzzaman M et al. Entry of a Six-Residue Antimicrobial Peptide Derived from Lactoferricin B into Single Vesicles and Escherichia coli Cells without Damaging their Membranes. 2017 Biochemistry pmid:28752991
Meijer AB et al. Membrane assembly of the bacteriophage Pf3 major coat protein. 2000 Biochemistry pmid:10821689
Hathcock JJ et al. Phospholipid regulates the activation of factor X by tissue factor/factor VIIa (TF/VIIa) via substrate and product interactions. 2005 Biochemistry pmid:15924438
Ellens H et al. Fusion of phosphatidylethanolamine-containing liposomes and mechanism of the L alpha-HII phase transition. 1986 Biochemistry pmid:3741846
Providence LL et al. Gramicidin channel function does not depend on phospholipid chirality. 1995 Biochemistry pmid:8845367
Raja MM and Kinne RK Interaction of C-terminal loop 13 of sodium-glucose cotransporter SGLT1 with lipid bilayers. 2005 Biochemistry pmid:15966736
Lindhout T et al. Thrombin generation and inactivation in the presence of antithrombin III and heparin. 1986 Biochemistry pmid:3790498