1,2-Dioleoyl-sn-Glycero-3-Phosphocholine is a lipid of Glycerophospholipids (GP) class. 1,2-dioleoyl-sn-glycero-3-phosphocholine is associated with abnormalities such as Exanthema, Renal tubular disorder, Nodule, Gigantism and Mycoses. The involved functions are known as Lysis, Encapsulation, Process, Uptake and Flow or discharge. 1,2-dioleoyl-sn-glycero-3-phosphocholine often locates in Cytoplasmic matrix, Endosomes, soluble, Endoplasmic Reticulum and Membrane. The associated genes with 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine are P4HTM gene, synthetic peptide, BCAR1 gene, PCNA gene and CNTNAP1 gene. The related lipids are Liposomes, 1,2-oleoylphosphatidylcholine, 1,2-distearoylphosphatidylethanolamine, Butanols and Cardiolipins. The related experimental models are Mouse Model and Xenograft Model.
To understand associated biological information of 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
1,2-Dioleoyl-sn-Glycero-3-Phosphocholine is suspected in Gigantism, Nodule, protrusion, DERMATITIS HERPETIFORMIS, FAMILIAL, Exanthema, Renal tubular disorder and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Ovarian Neoplasms | D010051 | 10 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Neuroblastoma | D009447 | 66 associated lipids |
| Niemann-Pick Diseases | D009542 | 25 associated lipids |
| Celiac Disease | D002446 | 16 associated lipids |
| Atherosclerosis | D050197 | 85 associated lipids |
| Respiratory Syncytial Virus Infections | D018357 | 10 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
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| Lipid concept | Cross reference | Weighted score | Related literatures |
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| Gene | Cross reference | Weighted score | Related literatures |
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Xenograft Model are used in the study 'Therapeutic targeting of PELP1 prevents ovarian cancer growth and metastasis.' (Chakravarty D et al., 2011).
Mouse Model are used in the study 'Therapeutic EphA2 gene targeting in vivo using neutral liposomal small interfering RNA delivery.' (Landen CN et al., 2005).
| Model | Cross reference | Weighted score | Related literatures |
|---|
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Yamamoto S et al. | Solubilization of Genistein in Phospholipid Vesicles and Their Atioxidant Capacity. | 2019 | J Oleo Sci | pmid:30542013 |
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| Kohn EM et al. | Role of Cationic Side Chains in the Antimicrobial Activity of C18G. | 2018 | Molecules | pmid:29401708 |
| Bhatia T | An image-processing method to detect sub-optical features based on understanding noise in intensity measurements. | 2018 | Eur. Biophys. J. | pmid:29392337 |
| Bennett M et al. | Molecular clutch drives cell response to surface viscosity. | 2018 | Proc. Natl. Acad. Sci. U.S.A. | pmid:29358406 |
| Cyr N et al. | The hydrophobic region of the peroxin 14: requirements for association with a glycosome mimetic membrane. | 2018 | Biochem. J. | pmid:29259081 |
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| Jaschonek S et al. | Intramolecular structural parameters are key modulators of the gel-liquid transition in coarse grained simulations of DPPC and DOPC lipid bilayers. | 2018 | Biochem. Biophys. Res. Commun. | pmid:29101041 |
| Meker S et al. | Amyloid-β Peptide Triggers Membrane Remodeling in Supported Lipid Bilayers Depending on Their Hydrophobic Thickness. | 2018 | Langmuir | pmid:30021071 |
| Halder A et al. | Lipid chain saturation and the cholesterol in the phospholipid membrane affect the spectroscopic properties of lipophilic dye nile red. | 2018 | Spectrochim Acta A Mol Biomol Spectrosc | pmid:28992460 |
| Menichetti R et al. | Efficient potential of mean force calculation from multiscale simulations: Solute insertion in a lipid membrane. | 2018 | Biochem. Biophys. Res. Commun. | pmid:28870809 |
| Liu X | Interactions of Silver Nanoparticles Formed in Situ on AFM Tips with Supported Lipid Bilayers. | 2018 | Langmuir | pmid:30109936 |
| Melby ES et al. | Peripheral Membrane Proteins Facilitate Nanoparticle Binding at Lipid Bilayer Interfaces. | 2018 | Langmuir | pmid:30102857 |
| Shirane D et al. | Development of an Alcohol Dilution-Lyophilization Method for Preparing Lipid Nanoparticles Containing Encapsulated siRNA. | 2018 | Biol. Pharm. Bull. | pmid:30068880 |
| Maity P et al. | Effect of Zwitterionic Phospholipid on the Interaction of Cationic Membranes with Monovalent Sodium Salts. | 2018 | Langmuir | pmid:30056708 |
| Wang L et al. | Membrane Reconstitution of Monoamine Oxidase Enzymes on Supported Lipid Bilayers. | 2018 | Langmuir | pmid:30049212 |
| Biswas KH et al. | Fabrication of Multicomponent, Spatially Segregated DNA and Protein-Functionalized Supported Membrane Microarray. | 2018 | Langmuir | pmid:30032610 |
| Mobarak E et al. | How to minimize dye-induced perturbations while studying biomembrane structure and dynamics: PEG linkers as a rational alternative. | 2018 | Biochim Biophys Acta Biomembr | pmid:30028957 |
| Wasif Baig M et al. | Orientation of Laurdan in Phospholipid Bilayers Influences Its Fluorescence: Quantum Mechanics and Classical Molecular Dynamics Study. | 2018 | Molecules | pmid:30011800 |
| Da Silveira Cavalcante L et al. | Effect of Liposome Treatment on Hemorheology and Metabolic Profile of Human Red Blood Cells During Hypothermic Storage. | 2018 | Biopreserv Biobank | pmid:30010418 |