1,2-Dioleoyl-sn-Glycero-3-Phosphocholine is a lipid of Glycerophospholipids (GP) class. 1,2-dioleoyl-sn-glycero-3-phosphocholine is associated with abnormalities such as Exanthema, Renal tubular disorder, Nodule, Gigantism and Mycoses. The involved functions are known as Lysis, Encapsulation, Process, Uptake and Flow or discharge. 1,2-dioleoyl-sn-glycero-3-phosphocholine often locates in Cytoplasmic matrix, Endosomes, soluble, Endoplasmic Reticulum and Membrane. The associated genes with 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine are P4HTM gene, synthetic peptide, BCAR1 gene, PCNA gene and CNTNAP1 gene. The related lipids are Liposomes, 1,2-oleoylphosphatidylcholine, 1,2-distearoylphosphatidylethanolamine, Butanols and Cardiolipins. The related experimental models are Mouse Model and Xenograft Model.
To understand associated biological information of 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
1,2-Dioleoyl-sn-Glycero-3-Phosphocholine is suspected in Gigantism, Nodule, protrusion, DERMATITIS HERPETIFORMIS, FAMILIAL, Exanthema, Renal tubular disorder and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Ovarian Neoplasms | D010051 | 10 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Neuroblastoma | D009447 | 66 associated lipids |
| Niemann-Pick Diseases | D009542 | 25 associated lipids |
| Celiac Disease | D002446 | 16 associated lipids |
| Atherosclerosis | D050197 | 85 associated lipids |
| Respiratory Syncytial Virus Infections | D018357 | 10 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
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| Lipid concept | Cross reference | Weighted score | Related literatures |
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| Gene | Cross reference | Weighted score | Related literatures |
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Xenograft Model are used in the study 'Therapeutic targeting of PELP1 prevents ovarian cancer growth and metastasis.' (Chakravarty D et al., 2011).
Mouse Model are used in the study 'Therapeutic EphA2 gene targeting in vivo using neutral liposomal small interfering RNA delivery.' (Landen CN et al., 2005).
| Model | Cross reference | Weighted score | Related literatures |
|---|
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
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| Sánchez-Murcia PA et al. | Exciton Localization on Ru-Based Photosensitizers Induced by Binding to Lipid Membranes. | 2018 | J Phys Chem Lett | pmid:29363982 |
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| Halder A et al. | Lipid chain saturation and the cholesterol in the phospholipid membrane affect the spectroscopic properties of lipophilic dye nile red. | 2018 | Spectrochim Acta A Mol Biomol Spectrosc | pmid:28992460 |
| Nagy-Szakal D et al. | Insights into myalgic encephalomyelitis/chronic fatigue syndrome phenotypes through comprehensive metabolomics. | 2018 | Sci Rep | pmid:29968805 |
| Menichetti R et al. | Efficient potential of mean force calculation from multiscale simulations: Solute insertion in a lipid membrane. | 2018 | Biochem. Biophys. Res. Commun. | pmid:28870809 |
| Terakawa MS et al. | Membrane-induced initial structure of α-synuclein control its amyloidogenesis on model membranes. | 2018 | Biochim. Biophys. Acta | pmid:29273335 |
| Bhojoo U et al. | Temperature induced lipid membrane restructuring and changes in nanomechanics. | 2018 | Biochim. Biophys. Acta | pmid:29248477 |
| Barroso MF et al. | Study of lipid peroxidation and ascorbic acid protective role in large unilamellar vesicles from a new electrochemical performance. | 2018 | Bioelectrochemistry | pmid:29247891 |
| Meynaq MYK et al. | Cationic interaction with phosphatidylcholine in a lipid cubic phase studied with electrochemical impedance spectroscopy and small angle X-ray scattering. | 2018 | J Colloid Interface Sci | pmid:29860201 |
| Tesei G et al. | Coarse-grained model of titrating peptides interacting with lipid bilayers. | 2018 | J Chem Phys | pmid:30599743 |
| Lai Y et al. | Highly efficient siRNA transfection in macrophages using apoptotic body-mimic Ca-PS lipopolyplex. | 2018 | Int J Nanomedicine | pmid:30425477 |
| Zhang N et al. | Partition of Glutamic Acid-Based Single-Chain and Gemini Amphiphiles into Phospholipid Membranes. | 2018 | Langmuir | pmid:30350992 |
| Yasuda T et al. | Nanosized Phase Segregation of Sphingomyelin and Dihydrosphigomyelin in Unsaturated Phosphatidylcholine Binary Membranes without Cholesterol. | 2018 | Langmuir | pmid:30350701 |
| Liu X | Interactions of Silver Nanoparticles Formed in Situ on AFM Tips with Supported Lipid Bilayers. | 2018 | Langmuir | pmid:30109936 |
| Melby ES et al. | Peripheral Membrane Proteins Facilitate Nanoparticle Binding at Lipid Bilayer Interfaces. | 2018 | Langmuir | pmid:30102857 |
| Shirane D et al. | Development of an Alcohol Dilution-Lyophilization Method for Preparing Lipid Nanoparticles Containing Encapsulated siRNA. | 2018 | Biol. Pharm. Bull. | pmid:30068880 |
| Maity P et al. | Effect of Zwitterionic Phospholipid on the Interaction of Cationic Membranes with Monovalent Sodium Salts. | 2018 | Langmuir | pmid:30056708 |
| Wang L et al. | Membrane Reconstitution of Monoamine Oxidase Enzymes on Supported Lipid Bilayers. | 2018 | Langmuir | pmid:30049212 |
| Biswas KH et al. | Fabrication of Multicomponent, Spatially Segregated DNA and Protein-Functionalized Supported Membrane Microarray. | 2018 | Langmuir | pmid:30032610 |
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| Wasif Baig M et al. | Orientation of Laurdan in Phospholipid Bilayers Influences Its Fluorescence: Quantum Mechanics and Classical Molecular Dynamics Study. | 2018 | Molecules | pmid:30011800 |
| Da Silveira Cavalcante L et al. | Effect of Liposome Treatment on Hemorheology and Metabolic Profile of Human Red Blood Cells During Hypothermic Storage. | 2018 | Biopreserv Biobank | pmid:30010418 |
| Liu D et al. | Peptide density targets and impedes triple negative breast cancer metastasis. | 2018 | Nat Commun | pmid:29973594 |
| Nomoto T et al. | Effects of Cholesterol Concentration and Osmolarity on the Fluidity and Membrane Tension of Free-standing Black Lipid Membranes. | 2018 | Anal Sci | pmid:29962374 |
| Kluzek M et al. | Kinetic evolution of DOPC lipid bilayers exposed to α-cyclodextrins. | 2018 | Soft Matter | pmid:29947414 |
| Guiselin B et al. | Dynamic Morphologies and Stability of Droplet Interface Bilayers. | 2018 | Phys. Rev. Lett. | pmid:29932701 |
| Bacellar IOL et al. | Permeability of DOPC bilayers under photoinduced oxidation: Sensitivity to photosensitizer. | 2018 | Biochim Biophys Acta Biomembr | pmid:29886032 |
| Mukherjee P et al. | Lipid and membrane recognition by the oxysterol binding protein and its phosphomimetic mutant using dual polarization interferometry. | 2018 | Biochim Biophys Acta Biomembr | pmid:29879417 |