1,2-Dioleoyl-sn-Glycero-3-Phosphocholine

1,2-Dioleoyl-sn-Glycero-3-Phosphocholine is a lipid of Glycerophospholipids (GP) class. 1,2-dioleoyl-sn-glycero-3-phosphocholine is associated with abnormalities such as Exanthema, Renal tubular disorder, Nodule, Gigantism and Mycoses. The involved functions are known as Lysis, Encapsulation, Process, Uptake and Flow or discharge. 1,2-dioleoyl-sn-glycero-3-phosphocholine often locates in Cytoplasmic matrix, Endosomes, soluble, Endoplasmic Reticulum and Membrane. The associated genes with 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine are P4HTM gene, synthetic peptide, BCAR1 gene, PCNA gene and CNTNAP1 gene. The related lipids are Liposomes, 1,2-oleoylphosphatidylcholine, 1,2-distearoylphosphatidylethanolamine, Butanols and Cardiolipins. The related experimental models are Mouse Model and Xenograft Model.

Cross Reference

Introduction

To understand associated biological information of 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine?

1,2-Dioleoyl-sn-Glycero-3-Phosphocholine is suspected in Gigantism, Nodule, protrusion, DERMATITIS HERPETIFORMIS, FAMILIAL, Exanthema, Renal tubular disorder and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Ovarian Neoplasms D010051 10 associated lipids
Edema D004487 152 associated lipids
Neuroblastoma D009447 66 associated lipids
Niemann-Pick Diseases D009542 25 associated lipids
Celiac Disease D002446 16 associated lipids
Atherosclerosis D050197 85 associated lipids
Respiratory Syncytial Virus Infections D018357 10 associated lipids
Total 8

PubChem Associated disorders and diseases

What pathways are associated with 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine?

Xenograft Model

Xenograft Model are used in the study 'Therapeutic targeting of PELP1 prevents ovarian cancer growth and metastasis.' (Chakravarty D et al., 2011).

Mouse Model

Mouse Model are used in the study 'Therapeutic EphA2 gene targeting in vivo using neutral liposomal small interfering RNA delivery.' (Landen CN et al., 2005).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

NCBI Entrez Crosslinks

All references with 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine

Download all related citations
Per page 10 20 50 100 | Total 1807
Authors Title Published Journal PubMed Link
Huque FT et al. Permeability through DOPC/dodecane membranes: measurement and LFER modelling. 2004 Eur J Pharm Sci pmid:15489123
Avdeef A and Tsinman O PAMPA--a drug absorption in vitro model 13. Chemical selectivity due to membrane hydrogen bonding: in combo comparisons of HDM-, DOPC-, and DS-PAMPA models. 2006 Eur J Pharm Sci pmid:16476536
Mader MA et al. Dynamics of viscous vesicles in shear flow. 2006 Eur Phys J E Soft Matter pmid:16607476
Erbe A and Sigel R Tilt angle of lipid acyl chains in unilamellar vesicles determined by ellipsometric light scattering. 2007 Eur Phys J E Soft Matter pmid:17431539
Balali-Mood K et al. Molecular dynamics simulations of a mixed DOPC/DOPG bilayer. 2003 Eur Phys J E Soft Matter pmid:15011033
Aeffner S et al. Membrane fusion intermediates and the effect of cholesterol: an in-house X-ray scattering study. 2009 Eur Phys J E Soft Matter pmid:19533189
Brüning B et al. Influence of charge density on bilayer bending rigidity in lipid vesicles: a combined dynamic light scattering and neutron spin-echo study. 2013 Eur Phys J E Soft Matter pmid:23884623
Traïkia M et al. Formation of unilamellar vesicles by repetitive freeze-thaw cycles: characterization by electron microscopy and 31P-nuclear magnetic resonance. 2000 Eur. Biophys. J. pmid:10968210
Bhatia T An image-processing method to detect sub-optical features based on understanding noise in intensity measurements. 2018 Eur. Biophys. J. pmid:29392337
Sanders JC et al. A small protein in model membranes: a time-resolved fluorescence and ESR study on the interaction of M13 coat protein with lipid bilayers. 1992 Eur. Biophys. J. pmid:1336450
Wolfe J et al. The interaction and fusion of bilayers formed from unsaturated lipids. 1991 Eur. Biophys. J. pmid:2060498
Mitra M et al. Fluorescence study of the effect of cholesterol on spectrin-aminophospholipid interactions. 2015 Eur. Biophys. J. pmid:26184723
Trépout S et al. Organization of reconstituted lipoprotein MexA onto supported lipid membrane. 2007 Eur. Biophys. J. pmid:17665187
Belička M et al. Effects of N,N-dimethyl-N-alkylamine-N-oxides on DOPC bilayers in unilamellar vesicles: small-angle neutron scattering study. 2014 Eur. Biophys. J. pmid:24687686
Rodríguez G et al. Characterization of new DOPC/DHPC platform for dermal applications. 2013 Eur. Biophys. J. pmid:23269481
Drechsler A et al. Effect of lipid on the conformation of the N-terminal region of equinatoxin II: a synchrotron radiation circular dichroism spectroscopic study. 2009 Eur. Biophys. J. pmid:19343335
Chen CP et al. Modulating the activity of the channel-forming segment of Vpr protein from HIV-1. 2010 Eur. Biophys. J. pmid:19629466
Hildebrandt P et al. Quantitative conformational analysis of cytochrome c bound to phospholipid vesicles studied by resonance Raman spectroscopy. 1990 Eur. Biophys. J. pmid:2162758
Vos WL et al. Molecular dynamics simulations reveal that AEDANS is an inert fluorescent probe for the study of membrane proteins. 2010 Eur. Biophys. J. pmid:19669748
Maaloum M A close encounter with DNA. 2003 Eur. Biophys. J. pmid:12908089
Govers-Riemslag JW et al. Prothrombin activation on dioleoylphosphatidylcholine membranes. 1994 Eur. J. Biochem. pmid:8119280
ter Beest MB and Hoekstra D Interaction of myelin basic protein with artificial membranes. Parameters governing binding, aggregation and dissociation. 1993 Eur. J. Biochem. pmid:7679637
Hoekstra D Topographical distribution of a membrane-inserted fluorescent phospholipid analogue during cell fusion. 1983 Exp. Cell Res. pmid:6301868
Sandra A et al. Morphological differentiation of murine neuroblastoma induced by liposomes. Lipid specificity and pathway of liposome uptake. 1981 Exp. Cell Res. pmid:7215457
Notter RH et al. Hysteresis in saturated phospholipid films and its potential relevance for lung surfactant function in vivo. 1982 Exp. Lung Res. pmid:6896686
Rozmanov D et al. Density based visualization for molecular simulation. 2014 Faraday Discuss. pmid:25341200
Bruno MJ et al. Interactions of drugs and amphiphiles with membranes: modulation of lipid bilayer elastic properties by changes in acyl chain unsaturation and protonation. 2013 Faraday Discuss. pmid:23805753
Czogalla A et al. Switchable domain partitioning and diffusion of DNA origami rods on membranes. 2013 Faraday Discuss. pmid:23805736
Baoukina S et al. Computer simulations of the phase separation in model membranes. 2013 Faraday Discuss. pmid:23805738
Aberg C et al. Lipid phase behaviour under steady state conditions. 2013 Faraday Discuss. pmid:23805741
Sanborn J et al. Transient pearling and vesiculation of membrane tubes under osmotic gradients. 2013 Faraday Discuss. pmid:23805742
Uline MJ and Szleifer I Mode specific elastic constants for the gel, liquid-ordered, and liquid-disordered phases of DPPC/DOPC/cholesterol model lipid bilayers. 2013 Faraday Discuss. pmid:23805743
Templer RH et al. Sensing isothermal changes in the lateral pressure in model membranes using di-pyrenyl phosphatidylcholine. 1998 Faraday Discuss. pmid:10822599
Anderluh G et al. Interaction of human stefin B in the prefibrillar oligomeric form with membranes. Correlation with cellular toxicity. 2005 FEBS J. pmid:15955063
Devanathan S et al. Effects of sphingomyelin, cholesterol and zinc ions on the binding, insertion and aggregation of the amyloid Abeta(1-40) peptide in solid-supported lipid bilayers. 2006 FEBS J. pmid:16689927
Drachmann ND et al. Comparing crystal structures of Ca(2+) -ATPase in the presence of different lipids. 2014 FEBS J. pmid:25103814
Nicolay K et al. Ethylene glycol causes acyl chain disordering in liquid-crystalline, unsaturated phospholipid model membranes, as measured by 2H NMR. 1986 FEBS Lett. pmid:3803574
Takei J et al. Generalised bilayer perturbation from peptide helix dimerisation at membrane surfaces: vesicle lysis induced by disulphide-dimerised melittin analogues. 1999 FEBS Lett. pmid:9923594
Suárez T et al. The pre-transmembrane region of the human immunodeficiency virus type-1 glycoprotein: a novel fusogenic sequence. 2000 FEBS Lett. pmid:10899326
Wang HW et al. Trimeric ring-like structure of ArsA ATPase. 2000 FEBS Lett. pmid:10708766
Speijer H et al. Partial coverage of phospholipid model membranes with annexin V may completely inhibit their degradation by phospholipase A2. 1997 FEBS Lett. pmid:9037194
Rokitskaya TI et al. Unsaturated lipids protect the integral membrane peptide gramicidin A from singlet oxygen. 2014 FEBS Lett. pmid:24613917
Ghosh R and Aggeler R Effect of lipid fluidity upon the activity and structure of the 39 kDa porin from Enterobacter cloacae 908S. 1987 FEBS Lett. pmid:2820792
Gallay J et al. Cardiolipin vesicles can accommodate cholesterol up to 0.80 mole fraction, i.e. one molecule per cardiolipin fatty acid chain. 1985 FEBS Lett. pmid:4054299
Duff KC et al. The secondary structure of influenza A M2 transmembrane domain. A circular dichroism study. 1992 FEBS Lett. pmid:1397324
Yan L et al. tBid forms a pore in the liposome membrane. 2003 FEBS Lett. pmid:14675771
Chupin V et al. The transit sequence of a chloroplast precursor protein reorients the lipids in monogalactosyl diglyceride containing bilayers. 1994 FEBS Lett. pmid:8062905
Schwarz G and Blochmann U Association of the wasp venom peptide mastoparan with electrically neutral lipid vesicles. Salt effects on partitioning and conformational state. 1993 FEBS Lett. pmid:8440373
Breukink E et al. Nucleotide and negatively charged lipid-dependent vesicle aggregation caused by SecA. Evidence that SecA contains two lipid-binding sites. 1993 FEBS Lett. pmid:8405403
Rinia HA et al. Visualizing detergent resistant domains in model membranes with atomic force microscopy. 2001 FEBS Lett. pmid:11457463
Jordi W et al. Phenethyl alcohol disorders phospholipid acyl chains and promotes translocation of the mitochondrial precursor protein apocytochrome c across a lipid bilayer. 1990 FEBS Lett. pmid:1689674
van Duyl BY et al. Influence of hydrophobic mismatch and palmitoylation on the association of transmembrane alpha-helical peptides with detergent-resistant membranes. 2002 FEBS Lett. pmid:12123808
Schindler H Formation of planar bilayers from artificial or native membrane vesicles. 1980 FEBS Lett. pmid:7194191
Cohen Simonsen A et al. Acyl-coenzyme A organizes laterally in membranes and is recognized specifically by acyl-coenzyme A binding protein. 2003 FEBS Lett. pmid:14527695
Akiyoshi K et al. Induction of neuron-like tubes and liposome networks by cooperative effect of gangliosides and phospholipids. 2003 FEBS Lett. pmid:12527358
Usai C et al. Capacitance--voltage relationship in phospholipid bilayers containing gangliosides. 1983 FEBS Lett. pmid:6617861
van Duyl BY et al. Sphingomyelin is much more effective than saturated phosphatidylcholine in excluding unsaturated phosphatidylcholine from domains formed with cholesterol. 2003 FEBS Lett. pmid:12860394
Mukherjee K et al. Common co-lipids, in synergy, impart high gene transfer properties to transfection-incompetent cationic lipids. 2005 FEBS Lett. pmid:15710428
Chen B et al. Role of reverse micelles on lipid oxidation in bulk oils: impact of phospholipids on antioxidant activity of α-tocopherol and Trolox. 2011 Food Funct pmid:21779568
Cozza G et al. Glutathione peroxidase 4-catalyzed reduction of lipid hydroperoxides in membranes: The polar head of membrane phospholipids binds the enzyme and addresses the fatty acid hydroperoxide group toward the redox center. 2017 Free Radic. Biol. Med. pmid:28709976
Jiang J et al. Designing inhibitors of cytochrome c/cardiolipin peroxidase complexes: mitochondria-targeted imidazole-substituted fatty acids. 2014 Free Radic. Biol. Med. pmid:24631490
Parasassi T et al. Cholesterol protects the phospholipid bilayer from oxidative damage. 1995 Free Radic. Biol. Med. pmid:7590402
Lambelet P et al. Radical exchange reactions between vitamin E, vitamin C and phospholipids in autoxidizing polyunsaturated lipids. 1994 Free Radic. Res. pmid:8012517
Micelli S et al. Effect of pH-variation on insertion and ion channel formation of human calcitonin into planar lipid bilayers. 2006 Front. Biosci. pmid:16720289
Hianik T et al. Interaction of adrenocorticotropin-(1-24)-tetracosapeptide with lipid bilayers. 1996 Gen. Physiol. Biophys. pmid:9076506
Gallová J et al. Effect of cholesterol on the bilayer thickness in unilamellar extruded DLPC and DOPC liposomes: SANS contrast variation study. 2004 Gen. Physiol. Biophys. pmid:15270132
Petrenko VI et al. Interaction of long-chain n-alcohols with fluid DOPC bilayers: a neutron diffraction study. 2010 Gen. Physiol. Biophys. pmid:21156998
Hianik T et al. Specific volume and compressibility of bilayer lipid membranes with incorporated Na,K-ATPase. 2011 Gen. Physiol. Biophys. pmid:21613669
Uhríková D et al. Small-angle neutron scattering study of N-dodecyl-N,N-dimethylamine N-oxide induced solubilization of dioleoylphosphatidylcholine bilayers in liposomes. 2001 Gen. Physiol. Biophys. pmid:11519689
Murugova TN et al. Study of interaction of long-chain n-alcohols with fluid DOPC bilayers by a lateral pressure sensitive fluorescence probe. 2012 Gen. Physiol. Biophys. pmid:22781827
Karlovská J et al. Effect of amphiphilic surfactant LDAO on the solubilization of DOPC vesicles and on the activity of Ca(2+)-ATPase reconstituted in DOPC vesicles. 2007 Gen. Physiol. Biophys. pmid:18281747
Cherny VV et al. The effect of rimantadine on the structure of model and biological membranes. 1989 Gen. Physiol. Biophys. pmid:2737460
Mills TT et al. Effects of cholesterol and unsaturated DOPC lipid on chain packing of saturated gel-phase DPPC bilayers. 2009 Gen. Physiol. Biophys. pmid:19592709
Elderdfi M et al. MPP1 interacts with DOPC/SM/Cholesterol in an artificial membrane system using Langmuir-Blodgett monolayer. 2017 Gen. Physiol. Biophys. pmid:28653654
Shangguan T et al. A novel N-acyl phosphatidylethanolamine-containing delivery vehicle for spermine-condensed plasmid DNA. 2000 Gene Ther. pmid:10822304
Lindhout T et al. Tissue factor pathway inhibitor: regulation of its inhibitory activity by phospholipid surfaces. 1996 Haemostasis pmid:8979115
Jiao X et al. Modulation of cellular immune response against hepatitis C virus nonstructural protein 3 by cationic liposome encapsulated DNA immunization. 2003 Hepatology pmid:12540796
Lai Y et al. Highly efficient siRNA transfection in macrophages using apoptotic body-mimic Ca-PS lipopolyplex. 2018 Int J Nanomedicine pmid:30425477
Chen C et al. The freeze-thawed and freeze-dried stability of cytarabine-encapsulated multivesicular liposomes. 2010 Int J Pharm pmid:20005932
Suganami A et al. Liposomally formulated phospholipid-conjugated indocyanine green for intra-operative brain tumor detection and resection. 2015 Int J Pharm pmid:26453781
Budai M et al. Studies on molecular interactions between nalidixic acid and liposomes. 2004 Int J Pharm pmid:15234796
Ringhieri P et al. Target selective micelles for bombesin receptors incorporating Au(III)-dithiocarbamato complexes. 2014 Int J Pharm pmid:25014371
Mignet N et al. Development of a liposomal formulation of the natural flavonoid fisetin. 2012 Int J Pharm pmid:21571054
Ramprasad MP et al. The sustained granulopoietic effect of progenipoietin encapsulated in multivesicular liposomes. 2003 Int J Pharm pmid:12878398
Ng K et al. The effects of polyethyleneglycol (PEG)-derived lipid on the activity of target-sensitive immunoliposome. 2000 Int J Pharm pmid:10606778
Peikov V et al. pH-dependent association of SN-38 with lipid bilayers of a novel liposomal formulation. 2005 Int J Pharm pmid:15996839
Hirano A et al. Structure changes of natively disordered Humanin in the presence of lipid. 2010 Int. J. Biol. Macromol. pmid:20116397
Wessels JM et al. Photodegradation of protoporphyrin-dimethylester in solution and in organized environments. 1993 Int. J. Radiat. Biol. pmid:7902387
Hirakata A et al. Effect of protein kinase C inhibitors and activators on corneal re-epithelialization in the rat. 1993 Invest. Ophthalmol. Vis. Sci. pmid:8425827
Ueno T et al. Peroxynitrite affects lidocaine by acting on membrane-constituting lipids. 2008 J Anesth pmid:19011794
Wei G et al. Lipid composition influences the membrane-disrupting activity of antimicrobial methacrylate co-polymers. 2011 J Biomater Sci Polym Ed pmid:21029518
Grasso G et al. Cell penetrating peptide modulation of membrane biomechanics by Molecular dynamics. 2018 J Biomech pmid:29631749
Babu S et al. Effect of size at the nanoscale and bilayer rigidity on skin diffusion of liposomes. 2009 J Biomed Mater Res A pmid:18770522
Ikeuchi R and Iwasaki Y High mineral affinity of polyphosphoester ionomer-phospholipid vesicles. 2013 J Biomed Mater Res A pmid:22829566
Tada DB et al. Effect of lipid coating on the interaction between silica nanoparticles and membranes. 2014 J Biomed Nanotechnol pmid:24730247
Woo Y et al. Hydrodynamic filtration in microfluidic channels as size-selection process for giant unilamellar vesicles. 2013 J Biomed Nanotechnol pmid:23621019
Pons T et al. Mechanisms of membrane potential sensing with second-harmonic generation microscopy. 2003 J Biomed Opt pmid:12880348
Kirchner SR et al. Membrane composition of jetted lipid vesicles: a Raman spectroscopy study. 2012 J Biophotonics pmid:22147675
Navrátilová V et al. Effect of cholesterol on the structure of membrane-attached cytochrome P450 3A4. 2015 J Chem Inf Model pmid:25654496
Stopar D et al. Exploring the local conformational space of a membrane protein by site-directed spin labeling. 2005 Nov-Dec J Chem Inf Model pmid:16309264