1,2-Dioleoyl-sn-Glycero-3-Phosphocholine

1,2-Dioleoyl-sn-Glycero-3-Phosphocholine is a lipid of Glycerophospholipids (GP) class. 1,2-dioleoyl-sn-glycero-3-phosphocholine is associated with abnormalities such as Exanthema, Renal tubular disorder, Nodule, Gigantism and Mycoses. The involved functions are known as Lysis, Encapsulation, Process, Uptake and Flow or discharge. 1,2-dioleoyl-sn-glycero-3-phosphocholine often locates in Cytoplasmic matrix, Endosomes, soluble, Endoplasmic Reticulum and Membrane. The associated genes with 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine are P4HTM gene, synthetic peptide, BCAR1 gene, PCNA gene and CNTNAP1 gene. The related lipids are Liposomes, 1,2-oleoylphosphatidylcholine, 1,2-distearoylphosphatidylethanolamine, Butanols and Cardiolipins. The related experimental models are Mouse Model and Xenograft Model.

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Introduction

To understand associated biological information of 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine?

1,2-Dioleoyl-sn-Glycero-3-Phosphocholine is suspected in Gigantism, Nodule, protrusion, DERMATITIS HERPETIFORMIS, FAMILIAL, Exanthema, Renal tubular disorder and other diseases in descending order of the highest number of associated sentences.

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Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Ovarian Neoplasms D010051 10 associated lipids
Edema D004487 152 associated lipids
Neuroblastoma D009447 66 associated lipids
Niemann-Pick Diseases D009542 25 associated lipids
Celiac Disease D002446 16 associated lipids
Atherosclerosis D050197 85 associated lipids
Respiratory Syncytial Virus Infections D018357 10 associated lipids
Total 8

PubChem Associated disorders and diseases

What pathways are associated with 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine?

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What functions are associated with 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine?


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Function Cross reference Weighted score Related literatures

What lipids are associated with 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine?

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What genes are associated with 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine?

Xenograft Model

Xenograft Model are used in the study 'Therapeutic targeting of PELP1 prevents ovarian cancer growth and metastasis.' (Chakravarty D et al., 2011).

Mouse Model

Mouse Model are used in the study 'Therapeutic EphA2 gene targeting in vivo using neutral liposomal small interfering RNA delivery.' (Landen CN et al., 2005).

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NCBI Entrez Crosslinks

All references with 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine

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Authors Title Published Journal PubMed Link
Wang TY et al. Fluorescence-based evaluation of the partitioning of lipids and lipidated peptides into liquid-ordered lipid microdomains: a model for molecular partitioning into "lipid rafts". 2000 Biophys. J. pmid:10920023
Uline MJ et al. Calculating partition coefficients of chain anchors in liquid-ordered and liquid-disordered phases. 2010 Biophys. J. pmid:20441752
Chiantia S et al. Effects of ceramide on liquid-ordered domains investigated by simultaneous AFM and FCS. 2006 Biophys. J. pmid:16565041
Bradshaw JP Phosphatydylglycerol promotes bilayer insertion of salmon calcitonin. 1997 Biophys. J. pmid:9129820
Sullan RM et al. Cholesterol-dependent nanomechanical stability of phase-segregated multicomponent lipid bilayers. 2010 Biophys. J. pmid:20643069
Sun Y et al. Kinetic process of beta-amyloid formation via membrane binding. 2010 Biophys. J. pmid:20643073
Vemparala S et al. Partitioning of anesthetics into a lipid bilayer and their interaction with membrane-bound peptide bundles. 2006 Biophys. J. pmid:16877515
Hirn R et al. The effect of S-layer protein adsorption and crystallization on the collective motion of a planar lipid bilayer studied by dynamic light scattering. 1999 Biophys. J. pmid:10512827
Melikyan GB et al. Voltage-dependent translocation of R18 and DiI across lipid bilayers leads to fluorescence changes. 1996 Biophys. J. pmid:8913605
Salesse C et al. Direct evidence for the formation of a monolayer from a bilayer. An ellipsometric study at the nitrogen-water interface. 1987 Biophys. J. pmid:3663839
Cabré EJ et al. Surfactant protein SP-B strongly modifies surface collapse of phospholipid vesicles: insights from a quartz crystal microbalance with dissipation. 2009 Biophys. J. pmid:19651035
Veatch SL and Keller SL Separation of liquid phases in giant vesicles of ternary mixtures of phospholipids and cholesterol. 2003 Biophys. J. pmid:14581208
Holland GP et al. Distinguishing individual lipid headgroup mobility and phase transitions in raft-forming lipid mixtures with 31P MAS NMR. 2006 Biophys. J. pmid:16533851
Marrink SJ and Mark AE Molecular view of hexagonal phase formation in phospholipid membranes. 2004 Biophys. J. pmid:15377528
Higgins MJ et al. Structured water layers adjacent to biological membranes. 2006 Biophys. J. pmid:16798815
Pandit SA et al. Simulation of the early stages of nano-domain formation in mixed bilayers of sphingomyelin, cholesterol, and dioleylphosphatidylcholine. 2004 Biophys. J. pmid:15339797
Shahedi V et al. Domain-formation in DOPC/SM bilayers studied by pfg-NMR: effect of sterol structure. 2006 Biophys. J. pmid:16829566
Pandit SA et al. Sphingomyelin-cholesterol domains in phospholipid membranes: atomistic simulation. 2004 Biophys. J. pmid:15298913
Koehorst RB et al. Lipid bilayer topology of the transmembrane alpha-helix of M13 Major coat protein and bilayer polarity profile by site-directed fluorescence spectroscopy. 2004 Biophys. J. pmid:15345527
Rossetti FF et al. Interaction of poly(L-lysine)-g-poly(ethylene glycol) with supported phospholipid bilayers. 2004 Biophys. J. pmid:15345550
Sjölund M et al. Hydrophobic molecules in lecithin-water systems. I. Formation of reversed hexagonal phases at high and low water contents. 1987 Biophys. J. pmid:2822159
Keller SL et al. Probability of alamethicin conductance states varies with nonlamellar tendency of bilayer phospholipids. 1993 Biophys. J. pmid:8369434
Hunter DG and Frisken BJ Effect of extrusion pressure and lipid properties on the size and polydispersity of lipid vesicles. 1998 Biophys. J. pmid:9635753
Girshman J et al. Gramicidin channels in phospholipid bilayers with unsaturated acyl chains. 1997 Biophys. J. pmid:9284299
Kucerka N et al. Lipid bilayer structure determined by the simultaneous analysis of neutron and X-ray scattering data. 2008 Biophys. J. pmid:18502796
Raghuraman H and Chattopadhyay A Interaction of melittin with membrane cholesterol: a fluorescence approach. 2004 Biophys. J. pmid:15454440
Manley S et al. Sorting of streptavidin protein coats on phase-separating model membranes. 2008 Biophys. J. pmid:18502811
Kozlovsky Y et al. Stalk phase formation: effects of dehydration and saddle splay modulus. 2004 Biophys. J. pmid:15454446
Lee TY et al. Tuning the Photocycle Kinetics of Bacteriorhodopsin in Lipid Nanodiscs. 2015 Biophys. J. pmid:26536266
An H et al. Material properties of lipid microdomains: force-volume imaging study of the effect of cholesterol on lipid microdomain rigidity. 2010 Biophys. J. pmid:20682261
Tajima K and Gershfeld NL Phospholipid surface bilayers at the air-water interface. I. Thermodynamic properties. 1985 Biophys. J. pmid:3838485
Garg S et al. Domain registration in raft-mimicking lipid mixtures studied using polymer-tethered lipid bilayers. 2007 Biophys. J. pmid:17114215
Heimburg T et al. Binding of peripheral proteins to mixed lipid membranes: effect of lipid demixing upon binding. 1999 Biophys. J. pmid:10233072
Marek A et al. Nanotube array method for studying lipid-induced conformational changes of a membrane protein by solid-state NMR. 2015 Biophys. J. pmid:25564843
Esposito C et al. Flicker spectroscopy of thermal lipid bilayer domain boundary fluctuations. 2007 Biophys. J. pmid:17644560
Siegel DP Energetics of intermediates in membrane fusion: comparison of stalk and inverted micellar intermediate mechanisms. 1993 Biophys. J. pmid:8298039
Murail S et al. Microsecond simulations indicate that ethanol binds between subunits and could stabilize an open-state model of a glycine receptor. 2011 Biophys. J. pmid:21463577
Schwarz G et al. Incorporation kinetics in a membrane, studied with the pore-forming peptide alamethicin. 1987 Biophys. J. pmid:3427183
Drolle E et al. Nanoscale electrostatic domains in cholesterol-laden lipid membranes create a target for amyloid binding. 2012 Biophys. J. pmid:22947946
Zhou Z et al. Studies of phospholipid hydration by high-resolution magic-angle spinning nuclear magnetic resonance. 1999 Biophys. J. pmid:9876150
Grant LM and Tiberg F Normal and lateral forces between lipid covered solids in solution: correlation with layer packing and structure. 2002 Biophys. J. pmid:11867453
Gandhavadi M et al. Structure, composition, and peptide binding properties of detergent soluble bilayers and detergent resistant rafts. 2002 Biophys. J. pmid:11867462
Malev VV et al. Syringomycin E channel: a lipidic pore stabilized by lipopeptide? 2002 Biophys. J. pmid:11916856
Baoukina S et al. Molecular structure of membrane tethers. 2012 Biophys. J. pmid:22768942
Armen RS et al. Phospholipid component volumes: determination and application to bilayer structure calculations. 1998 Biophys. J. pmid:9675175
Hung WC et al. Membrane-thinning effect of curcumin. 2008 Biophys. J. pmid:18310254
Becucci L et al. Thallous ion movements through gramicidin channels incorporated in lipid monolayers supported by mercury. 2002 Biophys. J. pmid:11806927
Pencer J et al. Osmotically induced shape changes of large unilamellar vesicles measured by dynamic light scattering. 2001 Biophys. J. pmid:11606284
Oreopoulos J and Yip CM Probing membrane order and topography in supported lipid bilayers by combined polarized total internal reflection fluorescence-atomic force microscopy. 2009 Biophys. J. pmid:19254557
Muddana HS et al. Tuning membrane phase separation using nonlipid amphiphiles. 2012 Biophys. J. pmid:22325271
Vanegas JM et al. Role of unsaturated lipid and ergosterol in ethanol tolerance of model yeast biomembranes. 2012 Biophys. J. pmid:22325273
Mui BL et al. Influence of transbilayer area asymmetry on the morphology of large unilamellar vesicles. 1995 Biophys. J. pmid:8519993
Alam Shibly SU et al. Experimental Estimation of Membrane Tension Induced by Osmotic Pressure. 2016 Biophys. J. pmid:27851942
Wiener MC and White SH Structure of a fluid dioleoylphosphatidylcholine bilayer determined by joint refinement of x-ray and neutron diffraction data. II. Distribution and packing of terminal methyl groups. 1992 Biophys. J. pmid:1547330
Siegel DP The Gaussian curvature elastic energy of intermediates in membrane fusion. 2008 Biophys. J. pmid:18805927
Wiener MC and White SH Structure of a fluid dioleoylphosphatidylcholine bilayer determined by joint refinement of x-ray and neutron diffraction data. III. Complete structure. 1992 Biophys. J. pmid:1547331
Murata M et al. Specificity of amphiphilic anionic peptides for fusion of phospholipid vesicles. 1993 Biophys. J. pmid:8471724
Gordeliy VI and Kiselev MA Definition of lipid membrane structural parameters from neutronographic experiments with the help of the strip function model. 1995 Biophys. J. pmid:8534812
Steinkühler J et al. Modulating Vesicle Adhesion by Electric Fields. 2016 Biophys. J. pmid:27705768
Perrin BS and Pastor RW Simulations of Membrane-Disrupting Peptides I: Alamethicin Pore Stability and Spontaneous Insertion. 2016 Biophys. J. pmid:27653483
Raines DE et al. Electron spin resonance studies of acyl chain motion in reconstituted nicotinic acetylcholine receptor membranes. 1995 Biophys. J. pmid:8527664
Sasaki H and White SH A novel fluorescent probe that senses the physical state of lipid bilayers. 2009 Biophys. J. pmid:19486685
Haluska CK et al. Combining fluorescence lifetime and polarization microscopy to discriminate phase separated domains in giant unilamellar vesicles. 2008 Biophys. J. pmid:18790852
Redondo-Morata L et al. Effect of Statins on the Nanomechanical Properties of Supported Lipid Bilayers. 2016 Biophys. J. pmid:27463138
Ruggiero A and Hudson B Analysis of the anisotropy decay of trans-parinaric acid in lipid bilayers. 1989 Biophys. J. pmid:2765650
Gleeson JT et al. Freezing and melting water in lamellar structures. 1994 Biophys. J. pmid:7948683
Cheng KH et al. Intramolecular excimer kinetics of fluorescent dipyrenyl lipids: 2. DOPE/DOPC membranes. 1994 Biophys. J. pmid:7948705
Chiu SW et al. Combined Monte Carlo and molecular dynamics simulation of fully hydrated dioleyl and palmitoyl-oleyl phosphatidylcholine lipid bilayers. 1999 Biophys. J. pmid:10545348
Yuan C et al. The size of lipid rafts: an atomic force microscopy study of ganglioside GM1 domains in sphingomyelin/DOPC/cholesterol membranes. 2002 Biophys. J. pmid:11964241
Piantanida L et al. Ions Modulate Stress-Induced Nanotexture in Supported Fluid Lipid Bilayers. 2017 Biophys. J. pmid:28746853
Mandal A et al. Structural Changes and Proapoptotic Peroxidase Activity of Cardiolipin-Bound Mitochondrial Cytochrome c. 2015 Biophys. J. pmid:26536264
Tarafdar PK et al. Phosphatidylserine-Dependent Catalysis of Stalk and Pore Formation by Synaptobrevin JMR-TMD Peptide. 2015 Biophys. J. pmid:26536263
Dietrich C et al. Lipid rafts reconstituted in model membranes. 2001 Biophys. J. pmid:11222302
Nielsen LK et al. Influence of product phase separation on phospholipase A(2) hydrolysis of supported phospholipid bilayers studied by force microscopy. 2002 Biophys. J. pmid:12414695
Benz R and Conti F Effects of hydrostatic pressure on lipid bilayer membranes. I. Influence on membrane thickness and activation volumes of lipophilic ion transport. 1986 Biophys. J. pmid:3730509
Parker A et al. Lateral distribution of cholesterol in dioleoylphosphatidylcholine lipid bilayers: cholesterol-phospholipid interactions at high cholesterol limit. 2004 Biophys. J. pmid:14990480
Van Mau N et al. Mixed monolayers of linear gramicidins and phospholipid. Surface pressure and surface potential studies. 1988 Biophys. J. pmid:2462931
Parra E et al. Hydrophobic pulmonary surfactant proteins SP-B and SP-C induce pore formation in planar lipid membranes: evidence for proteolipid pores. 2013 Biophys. J. pmid:23332067
Iben IE et al. Gd3+ vibronic side band spectroscopy. New optical probe of Ca2+ binding sites applied to biological macromolecules. 1991 Biophys. J. pmid:1907866
Blicher A et al. The temperature dependence of lipid membrane permeability, its quantized nature, and the influence of anesthetics. 2009 Biophys. J. pmid:19486680
Wiener MC et al. Structure of a fluid dioleoylphosphatidylcholine bilayer determined by joint refinement of x-ray and neutron diffraction data. I. Scaling of neutron data and the distributions of double bonds and water. 1991 Biophys. J. pmid:1932548
Heberle FA et al. Comparison of three ternary lipid bilayer mixtures: FRET and ESR reveal nanodomains. 2010 Biophys. J. pmid:21081079
Veatch SL and Keller SL A closer look at the canonical 'Raft Mixture' in model membrane studies. 2003 Biophys. J. pmid:12524324
Bezlyepkina N et al. Phase diagram and tie-line determination for the ternary mixture DOPC/eSM/cholesterol. 2013 Biophys. J. pmid:23561522
Shi L et al. Tilt and azimuthal angles of a transmembrane peptide: a comparison between molecular dynamics calculations and solid-state NMR data of sarcolipin in lipid membranes. 2009 Biophys. J. pmid:19413970
Silvius JR Fluorescence energy transfer reveals microdomain formation at physiological temperatures in lipid mixtures modeling the outer leaflet of the plasma membrane. 2003 Biophys. J. pmid:12885650
Huang HW Free energies of molecular bound states in lipid bilayers: lethal concentrations of antimicrobial peptides. 2009 Biophys. J. pmid:19383470
Andersson M et al. Conformational states of melittin at a bilayer interface. 2013 Biophys. J. pmid:23528098
Pathak P and London E The Effect of Membrane Lipid Composition on the Formation of Lipid Ultrananodomains. 2015 Biophys. J. pmid:26488654
Richter RP and Brisson AR Following the formation of supported lipid bilayers on mica: a study combining AFM, QCM-D, and ellipsometry. 2005 Biophys. J. pmid:15731391
Lum K et al. Exchange of Gramicidin between Lipid Bilayers: Implications for the Mechanism of Channel Formation. 2017 Biophys. J. pmid:29045870
Shangguan T et al. Morphological changes and fusogenic activity of influenza virus hemagglutinin. 1998 Biophys. J. pmid:9449309
Hughes ZE and Mancera RL Molecular mechanism of the synergistic effects of vitrification solutions on the stability of phospholipid bilayers. 2014 Biophys. J. pmid:24940779
Goulian M et al. Gramicidin channel kinetics under tension. 1998 Biophys. J. pmid:9449333
Xu Y et al. NMR study of volatile anesthetic binding to nicotinic acetylcholine receptors. 2000 Biophys. J. pmid:10653787
Maté S et al. N-nervonoylsphingomyelin (C24:1) prevents lateral heterogeneity in cholesterol-containing membranes. 2014 Biophys. J. pmid:24940778
Davis JH and Schmidt ML Critical behaviour in DOPC/DPPC/cholesterol mixtures: static (2)H NMR line shapes near the critical point. 2014 Biophys. J. pmid:24806929
Kalsi S et al. Shaped apertures in photoresist films enhance the lifetime and mechanical stability of suspended lipid bilayers. 2014 Biophys. J. pmid:24739164
Feller SE et al. Molecular dynamics simulation of unsaturated lipid bilayers at low hydration: parameterization and comparison with diffraction studies. 1997 Biophys. J. pmid:9370424
Rankin SE et al. The cholesterol dependence of activation and fast desensitization of the nicotinic acetylcholine receptor. 1997 Biophys. J. pmid:9370438