1,2-Dioleoyl-sn-Glycero-3-Phosphocholine is a lipid of Glycerophospholipids (GP) class. 1,2-dioleoyl-sn-glycero-3-phosphocholine is associated with abnormalities such as Exanthema, Renal tubular disorder, Nodule, Gigantism and Mycoses. The involved functions are known as Lysis, Encapsulation, Process, Uptake and Flow or discharge. 1,2-dioleoyl-sn-glycero-3-phosphocholine often locates in Cytoplasmic matrix, Endosomes, soluble, Endoplasmic Reticulum and Membrane. The associated genes with 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine are P4HTM gene, synthetic peptide, BCAR1 gene, PCNA gene and CNTNAP1 gene. The related lipids are Liposomes, 1,2-oleoylphosphatidylcholine, 1,2-distearoylphosphatidylethanolamine, Butanols and Cardiolipins. The related experimental models are Mouse Model and Xenograft Model.
To understand associated biological information of 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
1,2-Dioleoyl-sn-Glycero-3-Phosphocholine is suspected in Gigantism, Nodule, protrusion, DERMATITIS HERPETIFORMIS, FAMILIAL, Exanthema, Renal tubular disorder and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Ovarian Neoplasms | D010051 | 10 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Neuroblastoma | D009447 | 66 associated lipids |
| Niemann-Pick Diseases | D009542 | 25 associated lipids |
| Celiac Disease | D002446 | 16 associated lipids |
| Atherosclerosis | D050197 | 85 associated lipids |
| Respiratory Syncytial Virus Infections | D018357 | 10 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
| Lipid concept | Cross reference | Weighted score | Related literatures |
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| Gene | Cross reference | Weighted score | Related literatures |
|---|
Xenograft Model are used in the study 'Therapeutic targeting of PELP1 prevents ovarian cancer growth and metastasis.' (Chakravarty D et al., 2011).
Mouse Model are used in the study 'Therapeutic EphA2 gene targeting in vivo using neutral liposomal small interfering RNA delivery.' (Landen CN et al., 2005).
| Model | Cross reference | Weighted score | Related literatures |
|---|
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Moleiro LH et al. | Permeability modes in fluctuating lipid membranes with DNA-translocating pores. | 2017 | Adv Colloid Interface Sci | pmid:28735883 |
| Cozza G et al. | Glutathione peroxidase 4-catalyzed reduction of lipid hydroperoxides in membranes: The polar head of membrane phospholipids binds the enzyme and addresses the fatty acid hydroperoxide group toward the redox center. | 2017 | Free Radic. Biol. Med. | pmid:28709976 |
| Winkler PM et al. | Transient Nanoscopic Phase Separation in Biological Lipid Membranes Resolved by Planar Plasmonic Antennas. | 2017 | ACS Nano | pmid:28696660 |
| Chen Y et al. | Interactions of Phospholipid Vesicles with Cationic and Anionic Oligomeric Surfactants. | 2017 | J Phys Chem B | pmid:28686026 |
| Qi W et al. | Curing the Toxicity of Multi-Walled Carbon Nanotubes through Native Small-molecule Drugs. | 2017 | Sci Rep | pmid:28588210 |
| Potvin-Fournier K et al. | Membrane fluidity is a driving force for recoverin myristoyl immobilization in zwitterionic lipids. | 2017 | Biochem. Biophys. Res. Commun. | pmid:28684313 |
| Avakyan N et al. | Long-Range Ordering of Blunt-Ended DNA Tiles on Supported Lipid Bilayers. | 2017 | J. Am. Chem. Soc. | pmid:28783358 |
| Massiot J et al. | Impact of lipid composition and photosensitizer hydrophobicity on the efficiency of light-triggered liposomal release. | 2017 | Phys Chem Chem Phys | pmid:28425533 |
| Elderdfi M et al. | MPP1 interacts with DOPC/SM/Cholesterol in an artificial membrane system using Langmuir-Blodgett monolayer. | 2017 | Gen. Physiol. Biophys. | pmid:28653654 |
| Lindberg DJ et al. | Lipid membranes catalyse the fibril formation of the amyloid-β (1-42) peptide through lipid-fibril interactions that reinforce secondary pathways. | 2017 | Biochim. Biophys. Acta | pmid:28564579 |
| Przybyło M et al. | Changes in lipid membrane mechanics induced by di- and tri-phenyltins. | 2017 | Biochim. Biophys. Acta | pmid:28461050 |
| HÄ…c-Wydro K et al. | Effect of Cd and Cd/auxin mixtures on lipid monolayers - Model membrane studies on the role of auxins in phytoremediation of metal ions from contaminated environment. | 2017 | Biochim. Biophys. Acta | pmid:28343956 |
| Alvares DS et al. | Phosphatidylserine lipids and membrane order precisely regulate the activity of Polybia-MP1 peptide. | 2017 | Biochim. Biophys. Acta | pmid:28274844 |
| Petaccia M et al. | Synthesis, characterization and inclusion into liposomes of a new cationic pyrenyl amphiphile. | 2016 | Chem. Phys. Lipids | pmid:27521791 |
| Ishigami T et al. | Effect of Boundary Edge in DOPC/DPPC/Cholesterol Liposomes on Acceleration of l-Histidine Preferential Adsorption. | 2016 | Langmuir | pmid:27232976 |
| Sharmin S et al. | Effects of Lipid Composition on the Entry of Cell-Penetrating Peptide Oligoarginine into Single Vesicles. | 2016 | Biochemistry | pmid:27420912 |
| Pierrat P et al. | Cationic DOPC-Detergent Conjugates for Safe and Efficient in Vitro and in Vivo Nucleic Acid Delivery. | 2016 | Chembiochem | pmid:27380144 |
| Lee BL et al. | Permeation of the three aromatic dipeptides through lipid bilayers: Experimental and computational study. | 2016 | J Chem Phys | pmid:27369545 |
| Gillams RJ et al. | Comparative atomic-scale hydration of the ceramide and phosphocholine headgroup in solution and bilayer environments. | 2016 | J Chem Phys | pmid:27306021 |
| Segawa TF et al. | Water accessibility in a membrane-inserting peptide comparing Overhauser DNP and pulse EPR methods. | 2016 | J Chem Phys | pmid:27208942 |
| Klacsová M et al. | DOPC-DOPE composition dependent Lα-HII thermotropic phase transition: SAXD study. | 2016 | Chem. Phys. Lipids | pmid:27179406 |
| Karal MA et al. | Analysis of constant tension-induced rupture of lipid membranes using activation energy. | 2016 | Phys Chem Chem Phys | pmid:27125194 |
| Suga K et al. | Quantitative Monitoring of Microphase Separation Behaviors in Cationic Liposomes Using HHC, DPH, and Laurdan: Estimation of the Local Electrostatic Potentials in Microdomains. | 2016 | Langmuir | pmid:27022833 |
| Aoki PH et al. | Molecular-Level Modifications Induced by Photo-Oxidation of Lipid Monolayers Interacting with Erythrosin. | 2016 | Langmuir | pmid:27017835 |
| Bourlieu C et al. | Adsorption of gastric lipase onto multicomponent model lipid monolayers with phase separation. | 2016 | Colloids Surf B Biointerfaces | pmid:27011347 |
| Skeby KK et al. | Conformational Dynamics of the Human Islet Amyloid Polypeptide in a Membrane Environment: Toward the Aggregation Prone Form. | 2016 | Biochemistry | pmid:26953503 |
| Garcia-Fandiño R et al. | Lipid Bilayer Membrane Perturbation by Embedded Nanopores: A Simulation Study. | 2016 | ACS Nano | pmid:26943498 |
| Motta S et al. | What the cell surface does not see: The gene vector under the protein corona. | 2016 | Colloids Surf B Biointerfaces | pmid:26852100 |
| Rusciano G et al. | Insights into the interaction of the N-terminal amyloidogenic polypeptide of ApoA-I with model cellular membranes. | 2016 | Biochim. Biophys. Acta | pmid:26820473 |
| Wang Q et al. | Influence of Solution Chemistry and Soft Protein Coronas on the Interactions of Silver Nanoparticles with Model Biological Membranes. | 2016 | Environ. Sci. Technol. | pmid:26812241 |
| Calori IR and Tedesco AC | Lipid vesicles loading aluminum phthalocyanine chloride: Formulation properties and disaggregation upon intracellular delivery. | 2016 | J. Photochem. Photobiol. B, Biol. | pmid:27130963 |
| Gao J et al. | Aromaticity/Bulkiness of Surface Ligands to Promote the Interaction of Anionic Amphiphilic Gold Nanoparticles with Lipid Bilayers. | 2016 | Langmuir | pmid:26794292 |
| Purushothaman S et al. | Dependence of norfloxacin diffusion across bilayers on lipid composition. | 2016 | Soft Matter | pmid:26768751 |
| Achilles A et al. | Self-Assembly of X-Shaped Bolapolyphiles in Lipid Membranes: Solid-State NMR Investigations. | 2016 | Langmuir | pmid:26735449 |
| Kataoka-Hamai C et al. | Binding of Lipopolysaccharide and Cholesterol-Modified Gelatin on Supported Lipid Bilayers: Effect of Bilayer Area Confinement and Bilayer Edge Tension. | 2016 | Langmuir | pmid:26735125 |
| Schwierz N et al. | Mechanism of Reversible Peptide-Bilayer Attachment: Combined Simulation and Experimental Single-Molecule Study. | 2016 | Langmuir | pmid:26717083 |
| Drachmann ND and Olesen C | Lipid Exchange by Ultracentrifugation. | 2016 | Methods Mol. Biol. | pmid:26695050 |
| Cherniavskyi YK et al. | Interaction of C60 fullerenes with asymmetric and curved lipid membranes: a molecular dynamics study. | 2016 | Phys Chem Chem Phys | pmid:26608905 |
| Baumann A et al. | Tyrosine Hydroxylase Binding to Phospholipid Membranes Prompts Its Amyloid Aggregation and Compromises Bilayer Integrity. | 2016 | Sci Rep | pmid:28004763 |
| Wayteck L et al. | Hitchhiking nanoparticles: Reversible coupling of lipid-based nanoparticles to cytotoxic T lymphocytes. | 2016 | Biomaterials | pmid:26606450 |
| van der Wel C et al. | Lipid membrane-mediated attraction between curvature inducing objects. | 2016 | Sci Rep | pmid:27618764 |
| Kamiya K et al. | Cell-sized asymmetric lipid vesicles facilitate the investigation of asymmetric membranes. | 2016 | Nat Chem | pmid:27554415 |
| Barriga HM et al. | The effect of hydrostatic pressure on model membrane domain composition and lateral compressibility. | 2016 | Phys Chem Chem Phys | pmid:26601888 |
| Wang F et al. | Profiling Metal Oxides with Lipids: Magnetic Liposomal Nanoparticles Displaying DNA and Proteins. | 2016 | Angew. Chem. Int. Ed. Engl. | pmid:27539511 |
| Evans KO et al. | Feruloyl glycerol and 1,3-diferuloyl glycerol antioxidant behavior in phospholipid vesicles. | 2016 | Chem. Phys. Lipids | pmid:26561732 |
| Marin V et al. | Stable Free-Standing Lipid Bilayer Membranes in Norland Optical Adhesive 81 Microchannels. | 2016 | Anal. Chem. | pmid:27351219 |
| Chen SY et al. | One-Step Detection of Major Lipid Components in Submicroliter Volumes of Unpurified Liposome and Cell Suspensions. | 2016 | Anal. Chem. | pmid:27337108 |
| Heberle FA et al. | Subnanometer Structure of an Asymmetric Model Membrane: Interleaflet Coupling Influences Domain Properties. | 2016 | Langmuir | pmid:27128636 |
| Yang Y et al. | Self-assembly of size-controlled liposomes on DNA nanotemplates. | 2016 | Nat Chem | pmid:27102682 |
| Evans KO et al. | Octadecyl ferulate behavior in 1,2-Dioleoylphosphocholine liposomes. | 2016 | Spectrochim Acta A Mol Biomol Spectrosc | pmid:26332862 |
| Sennato S et al. | Salt-induced reentrant stability of polyion-decorated particles with tunable surface charge density. | 2016 | Colloids Surf B Biointerfaces | pmid:26117503 |
| Frewein M et al. | Lateral pressure-mediated protein partitioning into liquid-ordered/liquid-disordered domains. | 2016 | Soft Matter | pmid:27003910 |
| Zhang L et al. | Ionic Hydrogen Bonds and Lipid Packing Defects Determine the Binding Orientation and Insertion Depth of RecA on Multicomponent Lipid Bilayers. | 2016 | J Phys Chem B | pmid:27095675 |
| Grau-Campistany A et al. | Extending the Hydrophobic Mismatch Concept to Amphiphilic Membranolytic Peptides. | 2016 | J Phys Chem Lett | pmid:26963560 |
| Becucci L et al. | Channel-forming activity of syringopeptin 25A in mercury-supported lipid bilayers with a phosphatidylcholine distal leaflet. | 2016 | Bioelectrochemistry | pmid:26680109 |
| Nagle JF et al. | Determination of mosaicity in oriented stacks of lipid bilayers. | 2016 | Soft Matter | pmid:26677063 |
| Sarangi NK et al. | Nanoscale dynamics of phospholipids reveals an optimal assembly mechanism of pore-forming proteins in bilayer membranes. | 2016 | Phys Chem Chem Phys | pmid:27762416 |
| Jurak M | Effect of Lauryl Gallate on Wetting Properties of Organized Thin Phospholipid Films on Mica. | 2016 | J Phys Chem B | pmid:27332889 |
| Toscano-Flores LG et al. | Experimental Determination of High-Order Bending Elastic Constants of Lipid Bilayers. | 2016 | J Phys Chem B | pmid:27267752 |
| Pan J and Khadka NK | Kinetic Defects Induced by Melittin in Model Lipid Membranes: A Solution Atomic Force Microscopy Study. | 2016 | J Phys Chem B | pmid:27167473 |
| Karamdad K et al. | Studying the effects of asymmetry on the bending rigidity of lipid membranes formed by microfluidics. | 2016 | Chem. Commun. (Camb.) | pmid:27001410 |
| Alam Shibly SU et al. | Experimental Estimation of Membrane Tension Induced by Osmotic Pressure. | 2016 | Biophys. J. | pmid:27851942 |
| Thibado JK et al. | Influence of High pH and Cholesterol on Single Arginine-Containing Transmembrane Peptide Helices. | 2016 | Biochemistry | pmid:27782382 |
| Steinkühler J et al. | Modulating Vesicle Adhesion by Electric Fields. | 2016 | Biophys. J. | pmid:27705768 |
| Perrin BS and Pastor RW | Simulations of Membrane-Disrupting Peptides I: Alamethicin Pore Stability and Spontaneous Insertion. | 2016 | Biophys. J. | pmid:27653483 |
| Freudenthal O et al. | Nanoscale investigation of the interaction of colistin with model phospholipid membranes by Langmuir technique, and combined infrared and force spectroscopies. | 2016 | Biochim. Biophys. Acta | pmid:27480806 |
| Harrison PL et al. | Phospholipid dependent mechanism of smp24, an α-helical antimicrobial peptide from scorpion venom. | 2016 | Biochim. Biophys. Acta | pmid:27480803 |
| Redondo-Morata L et al. | Effect of Statins on the Nanomechanical Properties of Supported Lipid Bilayers. | 2016 | Biophys. J. | pmid:27463138 |
| Martfeld AN et al. | Ionization Properties of Histidine Residues in the Lipid Bilayer Membrane Environment. | 2016 | J. Biol. Chem. | pmid:27440045 |
| Sciacca MF et al. | The Role of Cholesterol in Driving IAPP-Membrane Interactions. | 2016 | Biophys. J. | pmid:27410742 |
| Kettiger H et al. | Interactions between silica nanoparticles and phospholipid membranes. | 2016 | Biochim. Biophys. Acta | pmid:27349734 |
| Savić F et al. | Geometry of the Contact Zone between Fused Membrane-Coated Beads Mimicking Cell-Cell Fusion. | 2016 | Biophys. J. | pmid:27224487 |
| Yang ST et al. | Line tension at lipid phase boundaries as driving force for HIV fusion peptide-mediated fusion. | 2016 | Nat Commun | pmid:27113279 |
| Shinoda W | Permeability across lipid membranes. | 2016 | Biochim. Biophys. Acta | pmid:27085977 |
| Nilsson T et al. | Lipid-mediated Protein-protein Interactions Modulate Respiration-driven ATP Synthesis. | 2016 | Sci Rep | pmid:27063297 |
| Shimobayashi SF et al. | Nanoscale hydration dynamics of DNA-lipid blend dry films: DNA-size dependency. | 2016 | Phys Chem Chem Phys | pmid:27840865 |
| Pezzoli D et al. | Characterization and Investigation of Redox-Sensitive Liposomes for Gene Delivery. | 2016 | Methods Mol. Biol. | pmid:27436322 |
| Fried ES et al. | Biodegradable, Tethered Lipid Bilayer-Microsphere Systems with Membrane-Integrated α-Helical Peptide Anchors. | 2016 | Langmuir | pmid:26972467 |
| Bailey KA and Schultz ZD | Tracking Bulk and Interfacial Diffusion Using Multiplex Coherent Anti-Stokes Raman Scattering Correlation Spectroscopy. | 2016 | J Phys Chem B | pmid:27322504 |
| Köster DV et al. | Actomyosin dynamics drive local membrane component organization in an in vitro active composite layer. | 2016 | Proc. Natl. Acad. Sci. U.S.A. | pmid:26929326 |
| Cardenas AE and Elber R | Markovian and Non-Markovian Modeling of Membrane Dynamics with Milestoning. | 2016 | J Phys Chem B | pmid:27016332 |
| Woo SY and Lee H | All-atom simulations and free-energy calculations of coiled-coil peptides with lipid bilayers: binding strength, structural transition, and effect on lipid dynamics. | 2016 | Sci Rep | pmid:26926570 |
| Orosz KS et al. | Photopolymerization of Dienoyl Lipids Creates Planar Supported Poly(lipid) Membranes with Retained Fluidity. | 2016 | Langmuir | pmid:26794208 |
| Watanabe H and Kawano R | Channel Current Analysis for Pore-forming Properties of an Antimicrobial Peptide, Magainin 1, Using the Droplet Contact Method. | 2016 | Anal Sci | pmid:26753706 |
| Niko Y et al. | Bright and photostable push-pull pyrene dye visualizes lipid order variation between plasma and intracellular membranes. | 2016 | Sci Rep | pmid:26750324 |
| Rupaimoole R et al. | Hypoxia-upregulated microRNA-630 targets Dicer, leading to increased tumor progression. | 2016 | Oncogene | pmid:26725326 |
| Drabik D et al. | The Effect of a Fluorophore Photo-Physics on the Lipid Vesicle Diffusion Coefficient Studied by Fluorescence Correlation Spectroscopy. | 2016 | J Fluoresc | pmid:26695945 |
| Chulkov EG and Ostroumova OS | Phloretin modulates the rate of channel formation by polyenes. | 2016 | Biochim. Biophys. Acta | pmid:26657529 |
| Onuki Y et al. | Membrane Microdomain Structures of Liposomes and Their Contribution to the Cellular Uptake Efficiency into HeLa Cells. | 2016 | Mol. Pharm. | pmid:26709741 |
| Lee J et al. | CHARMM-GUI Input Generator for NAMD, GROMACS, AMBER, OpenMM, and CHARMM/OpenMM Simulations Using the CHARMM36 Additive Force Field. | 2016 | J Chem Theory Comput | pmid:26631602 |
| Jurak M and Miñones J | Interactions of lauryl gallate with phospholipid components of biological membranes. | 2016 | Biochim. Biophys. Acta | pmid:27117642 |
| Capponi S et al. | Interleaflet mixing and coupling in liquid-disordered phospholipid bilayers. | 2016 | Biochim. Biophys. Acta | pmid:26657692 |
| Jeong DW et al. | Enhanced stability of freestanding lipid bilayer and its stability criteria. | 2016 | Sci Rep | pmid:27982049 |
| Drabik D et al. | The modified fluorescence based vesicle fluctuation spectroscopy technique for determination of lipid bilayer bending properties. | 2016 | Biochim. Biophys. Acta | pmid:26615919 |
| Hong CY et al. | Nonspecific Binding Domains in Lipid Membranes Induced by Phospholipase A2. | 2016 | Langmuir | pmid:27218880 |
| Fan ZA et al. | Revisit the Correlation between the Elastic Mechanics and Fusion of Lipid Membranes. | 2016 | Sci Rep | pmid:27534263 |
| Čechová P et al. | Ion Pathways in the Na/K-ATPase. | 2016 | J Chem Inf Model | pmid:27966362 |
| GarcÃa-Linares S et al. | Differential Effect of Membrane Composition on the Pore-Forming Ability of Four Different Sea Anemone Actinoporins. | 2016 | Biochemistry | pmid:27933793 |
| Olżyńska A et al. | Mixed DPPC/POPC Monolayers: All-atom Molecular Dynamics Simulations and Langmuir Monolayer Experiments. | 2016 | Biochim. Biophys. Acta | pmid:27664500 |
| Bhatia T et al. | Exploring the raft-hypothesis by probing planar bilayer patches of free-standing giant vesicles at nanoscale resolution, with and without Na,K-ATPase. | 2016 | Biochim. Biophys. Acta | pmid:27616046 |