1,2-Dioleoyl-sn-Glycero-3-Phosphocholine is a lipid of Glycerophospholipids (GP) class. 1,2-dioleoyl-sn-glycero-3-phosphocholine is associated with abnormalities such as Exanthema, Renal tubular disorder, Nodule, Gigantism and Mycoses. The involved functions are known as Lysis, Encapsulation, Process, Uptake and Flow or discharge. 1,2-dioleoyl-sn-glycero-3-phosphocholine often locates in Cytoplasmic matrix, Endosomes, soluble, Endoplasmic Reticulum and Membrane. The associated genes with 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine are P4HTM gene, synthetic peptide, BCAR1 gene, PCNA gene and CNTNAP1 gene. The related lipids are Liposomes, 1,2-oleoylphosphatidylcholine, 1,2-distearoylphosphatidylethanolamine, Butanols and Cardiolipins. The related experimental models are Mouse Model and Xenograft Model.
To understand associated biological information of 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
1,2-Dioleoyl-sn-Glycero-3-Phosphocholine is suspected in Gigantism, Nodule, protrusion, DERMATITIS HERPETIFORMIS, FAMILIAL, Exanthema, Renal tubular disorder and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Ovarian Neoplasms | D010051 | 10 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Neuroblastoma | D009447 | 66 associated lipids |
| Niemann-Pick Diseases | D009542 | 25 associated lipids |
| Celiac Disease | D002446 | 16 associated lipids |
| Atherosclerosis | D050197 | 85 associated lipids |
| Respiratory Syncytial Virus Infections | D018357 | 10 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
| Gene | Cross reference | Weighted score | Related literatures |
|---|
Xenograft Model are used in the study 'Therapeutic targeting of PELP1 prevents ovarian cancer growth and metastasis.' (Chakravarty D et al., 2011).
Mouse Model are used in the study 'Therapeutic EphA2 gene targeting in vivo using neutral liposomal small interfering RNA delivery.' (Landen CN et al., 2005).
| Model | Cross reference | Weighted score | Related literatures |
|---|
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Karal MA et al. | Analysis of constant tension-induced rupture of lipid membranes using activation energy. | 2016 | Phys Chem Chem Phys | pmid:27125194 |
| Calori IR and Tedesco AC | Lipid vesicles loading aluminum phthalocyanine chloride: Formulation properties and disaggregation upon intracellular delivery. | 2016 | J. Photochem. Photobiol. B, Biol. | pmid:27130963 |
| Zhang L et al. | Ionic Hydrogen Bonds and Lipid Packing Defects Determine the Binding Orientation and Insertion Depth of RecA on Multicomponent Lipid Bilayers. | 2016 | J Phys Chem B | pmid:27095675 |
| Toscano-Flores LG et al. | Experimental Determination of High-Order Bending Elastic Constants of Lipid Bilayers. | 2016 | J Phys Chem B | pmid:27267752 |
| Pan J and Khadka NK | Kinetic Defects Induced by Melittin in Model Lipid Membranes: A Solution Atomic Force Microscopy Study. | 2016 | J Phys Chem B | pmid:27167473 |
| Sciacca MF et al. | The Role of Cholesterol in Driving IAPP-Membrane Interactions. | 2016 | Biophys. J. | pmid:27410742 |
| Kettiger H et al. | Interactions between silica nanoparticles and phospholipid membranes. | 2016 | Biochim. Biophys. Acta | pmid:27349734 |
| Savić F et al. | Geometry of the Contact Zone between Fused Membrane-Coated Beads Mimicking Cell-Cell Fusion. | 2016 | Biophys. J. | pmid:27224487 |
| Ackerman DG and Feigenson GW | Lipid bilayers: clusters, domains and phases. | 2015 | Essays Biochem. | pmid:25658342 |
| Kulig W et al. | Experimental determination and computational interpretation of biophysical properties of lipid bilayers enriched by cholesteryl hemisuccinate. | 2015 | Biochim. Biophys. Acta | pmid:25450348 |
| Smirnova YG and Müller M | Calculation of membrane bending rigidity using field-theoretic umbrella sampling. | 2015 | J Chem Phys | pmid:26723640 |
| Tachikawa S et al. | Localization-dependent cell-killing effects of protoporphyrin (PPIX)-lipid micelles and liposomes in photodynamic therapy. | 2015 | Bioorg. Med. Chem. | pmid:26602828 |
| Khadka NK et al. | Macroscopic and Nanoscopic Heterogeneous Structures in a Three-Component Lipid Bilayer Mixtures Determined by Atomic Force Microscopy. | 2015 | Langmuir | pmid:26506226 |
| Jeppesen JC et al. | Slow Relaxation of Shape and Orientational Texture in Membrane Gel Domains. | 2015 | Langmuir | pmid:26501924 |
| Dols-Perez A et al. | Nanoscale electric polarizability of ultrathin biolayers on insulating substrates by electrostatic force microscopy. | 2015 | Nanoscale | pmid:26488226 |
| Liu X and Chen KL | Interactions of Graphene Oxide with Model Cell Membranes: Probing Nanoparticle Attachment and Lipid Bilayer Disruption. | 2015 | Langmuir | pmid:26466194 |
| Suganami A et al. | Liposomally formulated phospholipid-conjugated indocyanine green for intra-operative brain tumor detection and resection. | 2015 | Int J Pharm | pmid:26453781 |
| Hirtz M et al. | Selective Binding of DNA Origami on Biomimetic Lipid Patches. | 2015 | Small | pmid:26389563 |
| Moniruzzaman M et al. | Antimicrobial Peptide Lactoferricin B-Induced Rapid Leakage of Internal Contents from Single Giant Unilamellar Vesicles. | 2015 | Biochemistry | pmid:26368853 |
| Yokota K and Ogino T | Phase separation in lipid bilayer membranes induced by intermixing at a boundary of two phases with different components. | 2015 | Chem. Phys. Lipids | pmid:26363303 |
| Wuttke S et al. | MOF nanoparticles coated by lipid bilayers and their uptake by cancer cells. | 2015 | Chem. Commun. (Camb.) | pmid:26359316 |
| Baczynski K et al. | A computer model of a polyunsaturated monogalactolipid bilayer. | 2015 | Biochimie | pmid:26348551 |
| Karal MA and Yamazaki M | Communication: Activation energy of tension-induced pore formation in lipid membranes. | 2015 | J Chem Phys | pmid:26328811 |
| Poznik M et al. | The interface makes a difference: lanthanide ion coated vesicles hydrolyze phosphodiesters. | 2015 | Org. Biomol. Chem. | pmid:26269206 |
| Moerkerke S et al. | Selective Recognition of Phosphatidylcholine Lipids by a Biomimetic Calix[6]tube Receptor. | 2015 | J. Org. Chem. | pmid:26258943 |
| Kent B et al. | Direct Comparison of Disaccharide Interaction with Lipid Membranes at Reduced Hydrations. | 2015 | Langmuir | pmid:26225718 |
| Yilmaz N and Kobayashi T | Visualization of Lipid Membrane Reorganization Induced by a Pore-Forming Toxin Using High-Speed Atomic Force Microscopy. | 2015 | ACS Nano | pmid:26222645 |
| Becucci L and Guidelli R | Can gramicidin ion channel affect the dipole potential of neighboring phospholipid headgroups? | 2015 | Bioelectrochemistry | pmid:26190793 |
| Lee H et al. | Effects of imidazolium-based ionic liquids on the stability and dynamics of gramicidin A and lipid bilayers at different salt concentrations. | 2015 | J. Mol. Graph. Model. | pmid:26188795 |
| Scholtysek P et al. | Unusual triskelion patterns and dye-labelled GUVs: consequences of the interaction of cholesterol-containing linear-hyperbranched block copolymers with phospholipids. | 2015 | Soft Matter | pmid:26133098 |
| Zaba C et al. | Functional Cell Adhesion Receptors (Integrins) in Polymeric Architectures. | 2015 | Chembiochem | pmid:26077820 |
| Villa CC et al. | Singularities in the physicochemical properties of spontaneous AOT-BHD unilamellar vesicles in comparison with DOPC vesicles. | 2015 | Phys Chem Chem Phys | pmid:26068595 |
| Bhatia T et al. | Tubular growth and bead formation in the lyotropic lamellar phase of a lipid. | 2015 | Soft Matter | pmid:26066670 |
| Lin Q et al. | Decreasing Transmembrane Segment Length Greatly Decreases Perfringolysin O Pore Size. | 2015 | J. Membr. Biol. | pmid:25850715 |
| Schmidt TF et al. | Binding of methylene blue onto Langmuir monolayers representing cell membranes may explain its efficiency as photosensitizer in photodynamic therapy. | 2015 | Langmuir | pmid:25798992 |
| Basit H et al. | Aqueous-filled polymer microcavity arrays: versatile & stable lipid bilayer platforms offering high lateral mobility to incorporated membrane proteins. | 2015 | Analyst | pmid:25798456 |
| Rhéault JF et al. | Molecular model of hemoglobin N from Mycobacterium tuberculosis bound to lipid bilayers: a combined spectroscopic and computational study. | 2015 | Biochemistry | pmid:25723781 |
| Johnson MA et al. | Equivalent Isopropanol Concentrations of Aromatic Amino Acids Interactions with Lipid Vesicles. | 2015 | J. Membr. Biol. | pmid:25691267 |
| Henry S et al. | Interaction of Aβ(1-42) amyloids with lipids promotes "off-pathway" oligomerization and membrane damage. | 2015 | Biomacromolecules | pmid:25689632 |
| Tabaei SR et al. | Solvent-assisted lipid self-assembly at hydrophilic surfaces: factors influencing the formation of supported membranes. | 2015 | Langmuir | pmid:25679066 |
| Wei X et al. | Effects of SiO2 nanoparticles on phospholipid membrane integrity and fluidity. | 2015 | J. Hazard. Mater. | pmid:25661168 |
| Eggeling C | Super-resolution optical microscopy of lipid plasma membrane dynamics. | 2015 | Essays Biochem. | pmid:25658345 |
| Ashrafzadeh P and Parmryd I | Methods applicable to membrane nanodomain studies? | 2015 | Essays Biochem. | pmid:25658344 |
| Carravilla P et al. | Two-photon Laurdan studies of the ternary lipid mixture DOPC:SM:cholesterol reveal a single liquid phase at sphingomyelin:cholesterol ratios lower than 1. | 2015 | Langmuir | pmid:25658036 |
| Navrátilová V et al. | Effect of cholesterol on the structure of membrane-attached cytochrome P450 3A4. | 2015 | J Chem Inf Model | pmid:25654496 |
| Oude Blenke E et al. | Liposome functionalization with copper-free "click chemistry". | 2015 | J Control Release | pmid:25626085 |
| Larsen JB et al. | Membrane curvature enables N-Ras lipid anchor sorting to liquid-ordered membrane phases. | 2015 | Nat. Chem. Biol. | pmid:25622090 |
| Moskovitz Y and Yang H | Modelling of noble anaesthetic gases and high hydrostatic pressure effects in lipid bilayers. | 2015 | Soft Matter | pmid:25612767 |
| Pezeshkian W et al. | The effects of globotriaosylceramide tail saturation level on bilayer phases. | 2015 | Soft Matter | pmid:25575293 |
| Oh E et al. | Contribution of temperature to deformation of adsorbed vesicles studied by nanoplasmonic biosensing. | 2015 | Langmuir | pmid:25531903 |
| DeWitt BN and Dunn RC | Interaction of cholesterol in ternary lipid mixtures investigated using single-molecule fluorescence. | 2015 | Langmuir | pmid:25531175 |
| Almeda D et al. | Minimizing antibody surface density on liposomes while sustaining cytokine-activated EC targeting. | 2015 | Biomaterials | pmid:25522963 |
| Steudle AK et al. | Hydrolysis of hydrophobic esters in a bicontinuous microemulsion catalysed by lipase B from Candida antarctica. | 2015 | Chemistry | pmid:25512180 |
| Yesylevskyy SO and Demchenko AP | Cholesterol behavior in asymmetric lipid bilayers: insights from molecular dynamics simulations. | 2015 | Methods Mol. Biol. | pmid:25331142 |
| Hu PC and Malmstadt N | Asymmetric giant lipid vesicle fabrication. | 2015 | Methods Mol. Biol. | pmid:25331129 |
| Lee TY et al. | Tuning the Photocycle Kinetics of Bacteriorhodopsin in Lipid Nanodiscs. | 2015 | Biophys. J. | pmid:26536266 |
| Han CT and Chao L | Using a patterned grating structure to create lipid bilayer platforms insensitive to air bubbles. | 2015 | Lab Chip | pmid:25316602 |
| Becucci L et al. | The effect of the hydrophilic spacer length on the functionality of a mercury-supported tethered bilayer lipid membrane. | 2015 | Bioelectrochemistry | pmid:25180906 |
| Arduin A et al. | Regulation of PLCβ2 by the electrostatic and mechanical properties of lipid bilayers. | 2015 | Sci Rep | pmid:26243281 |
| Karami L and Jalili S | Effects of cholesterol concentration on the interaction of cytarabine with lipid membranes: a molecular dynamics simulation study. | 2015 | J. Biomol. Struct. Dyn. | pmid:25068451 |
| Mitra M et al. | Fluorescence study of the effect of cholesterol on spectrin-aminophospholipid interactions. | 2015 | Eur. Biophys. J. | pmid:26184723 |
| Marek A et al. | Nanotube array method for studying lipid-induced conformational changes of a membrane protein by solid-state NMR. | 2015 | Biophys. J. | pmid:25564843 |
| Aoyagi S et al. | ToF-SIMS observation for evaluating the interaction between amyloid β and lipid membranes. | 2015 | Anal Bioanal Chem | pmid:25687682 |
| Cheng CY et al. | DMSO induces dehydration near lipid membrane surfaces. | 2015 | Biophys. J. | pmid:26200868 |
| Rui L et al. | Reduced graphene oxide directed self-assembly of phospholipid monolayers in liquid and gel phases. | 2015 | Biochim. Biophys. Acta | pmid:25724816 |
| Shimokawa N et al. | Physical properties of the hybrid lipid POPC on micrometer-sized domains in mixed lipid membranes. | 2015 | Phys Chem Chem Phys | pmid:26214181 |
| Sridhar A et al. | Coarse-grain molecular dynamics study of fullerene transport across a cell membrane. | 2015 | J Chem Phys | pmid:26178127 |
| Mandal A et al. | Structural Changes and Proapoptotic Peroxidase Activity of Cardiolipin-Bound Mitochondrial Cytochrome c. | 2015 | Biophys. J. | pmid:26536264 |
| Tarafdar PK et al. | Phosphatidylserine-Dependent Catalysis of Stalk and Pore Formation by Synaptobrevin JMR-TMD Peptide. | 2015 | Biophys. J. | pmid:26536263 |
| Ohno M et al. | Changes in Interfacial Tension of a Lipid Membrane Formed at the Water/Chloroform Interface upon DNA Complex Formation. | 2015 | Anal Sci | pmid:26460361 |
| Chen Z et al. | Regulation of membrane-shape transitions induced by I-BAR domains. | 2015 | Biophys. J. | pmid:26200865 |
| Chavarha M et al. | Hydrophobic surfactant proteins strongly induce negative curvature. | 2015 | Biophys. J. | pmid:26153706 |
| Moser von Filseck J et al. | A phosphatidylinositol-4-phosphate powered exchange mechanism to create a lipid gradient between membranes. | 2015 | Nat Commun | pmid:25849868 |
| Rasmussen T et al. | Properties of the Mechanosensitive Channel MscS Pore Revealed by Tryptophan Scanning Mutagenesis. | 2015 | Biochemistry | pmid:26126964 |
| Adams PG et al. | Exploiting lipopolysaccharide-induced deformation of lipid bilayers to modify membrane composition and generate two-dimensional geometric membrane array patterns. | 2015 | Sci Rep | pmid:26015293 |
| Yasuda T et al. | Deuterium NMR of raft model membranes reveals domain-specific order profiles and compositional distribution. | 2015 | Biophys. J. | pmid:25992728 |
| de Sá MM et al. | Understanding Miltefosine-Membrane Interactions Using Molecular Dynamics Simulations. | 2015 | Langmuir | pmid:25819781 |
| Lin Q and London E | Ordered raft domains induced by outer leaflet sphingomyelin in cholesterol-rich asymmetric vesicles. | 2015 | Biophys. J. | pmid:25954879 |
| Kowal J et al. | Hybrid polymer-lipid films as platforms for directed membrane protein insertion. | 2015 | Langmuir | pmid:25849126 |
| Singh J and Ranganathan R | Mixing of oxidized and bilayer phospholipids. | 2015 | Biochim. Biophys. Acta | pmid:25839354 |
| Ando J et al. | Sphingomyelin distribution in lipid rafts of artificial monolayer membranes visualized by Raman microscopy. | 2015 | Proc. Natl. Acad. Sci. U.S.A. | pmid:25825736 |
| GarcÃa-Linares S et al. | The effect of cholesterol on the long-range network of interactions established among sea anemone Sticholysin II residues at the water-membrane interface. | 2015 | Mar Drugs | pmid:25815890 |
| Gay A et al. | Switch-like responses of two cholesterol sensors do not require protein oligomerization in membranes. | 2015 | Biophys. J. | pmid:25809258 |
| Barriga HM et al. | Buffer-induced swelling and vesicle budding in binary lipid mixtures of dioleoylphosphatidylcholine:dioleoylphosphatidylethanolamine and dioleoylphosphatidylcholine:lysophosphatidylcholine using small-angle X-ray scattering and ³¹P static NMR. | 2015 | Langmuir | pmid:25738977 |
| Panahi A and Brooks CL | Membrane environment modulates the pKa values of transmembrane helices. | 2015 | J Phys Chem B | pmid:25734901 |
| Balleza D et al. | Effects of neurosteroids on a model membrane including cholesterol: A micropipette aspiration study. | 2015 | Biochim. Biophys. Acta | pmid:25660752 |
| Sacchi M et al. | Effect of neurosteroids on a model lipid bilayer including cholesterol: An Atomic Force Microscopy study. | 2015 | Biochim. Biophys. Acta | pmid:25620773 |
| Barnoud J et al. | C₆₀ fullerene promotes lung monolayer collapse. | 2015 | J R Soc Interface | pmid:25589571 |
| Grosjean K et al. | Differential effect of plant lipids on membrane organization: specificities of phytosphingolipids and phytosterols. | 2015 | J. Biol. Chem. | pmid:25575593 |
| Lane RE et al. | Analysis of exosome purification methods using a model liposome system and tunable-resistive pulse sensing. | 2015 | Sci Rep | pmid:25559219 |
| Becucci L et al. | Channel-forming activity of syringomycin E in two mercury-supported biomimetic membranes. | 2015 | Biochim. Biophys. Acta | pmid:25554594 |
| Lhor M et al. | Structure of the N-terminal segment of human retinol dehydrogenase 11 and its preferential lipid binding using model membranes. | 2015 | Biochim. Biophys. Acta | pmid:25542782 |
| Bulacu M and Sevink GJ | Computational insight in the role of fusogenic lipopeptides at the onset of liposome fusion. | 2015 | Biochim. Biophys. Acta | pmid:25528473 |
| Dabkowska AP et al. | Assembly of RNA nanostructures on supported lipid bilayers. | 2015 | Nanoscale | pmid:25417592 |
| Tavano R et al. | The peculiar N- and (-termini of trichogin GA IV are needed for membrane interaction and human cell death induction at doses lacking antibiotic activity. | 2015 | Biochim. Biophys. Acta | pmid:25306964 |
| Liu Y and Mark Worden R | Size dependent disruption of tethered lipid bilayers by functionalized polystyrene nanoparticles. | 2015 | Biochim. Biophys. Acta | pmid:25285435 |
| Chulkov EG et al. | Membrane dipole modifiers modulate single-length nystatin channels via reducing elastic stress in the vicinity of the lipid mouth of a pore. | 2015 | Biochim. Biophys. Acta | pmid:25223717 |
| Evans KO et al. | Hydroxytyrosol and tyrosol esters partitioning into, location within, and effect on DOPC liposome bilayer behavior. | 2015 | Biochim. Biophys. Acta | pmid:25687972 |
| Pathak P and London E | The Effect of Membrane Lipid Composition on the Formation of Lipid Ultrananodomains. | 2015 | Biophys. J. | pmid:26488654 |
| Madej BD et al. | A Parameterization of Cholesterol for Mixed Lipid Bilayer Simulation within the Amber Lipid14 Force Field. | 2015 | J Phys Chem B | pmid:26359797 |