1,2-Dioleoyl-sn-Glycero-3-Phosphocholine is a lipid of Glycerophospholipids (GP) class. 1,2-dioleoyl-sn-glycero-3-phosphocholine is associated with abnormalities such as Exanthema, Renal tubular disorder, Nodule, Gigantism and Mycoses. The involved functions are known as Lysis, Encapsulation, Process, Uptake and Flow or discharge. 1,2-dioleoyl-sn-glycero-3-phosphocholine often locates in Cytoplasmic matrix, Endosomes, soluble, Endoplasmic Reticulum and Membrane. The associated genes with 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine are P4HTM gene, synthetic peptide, BCAR1 gene, PCNA gene and CNTNAP1 gene. The related lipids are Liposomes, 1,2-oleoylphosphatidylcholine, 1,2-distearoylphosphatidylethanolamine, Butanols and Cardiolipins. The related experimental models are Mouse Model and Xenograft Model.
To understand associated biological information of 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
1,2-Dioleoyl-sn-Glycero-3-Phosphocholine is suspected in Gigantism, Nodule, protrusion, DERMATITIS HERPETIFORMIS, FAMILIAL, Exanthema, Renal tubular disorder and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Ovarian Neoplasms | D010051 | 10 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Neuroblastoma | D009447 | 66 associated lipids |
| Niemann-Pick Diseases | D009542 | 25 associated lipids |
| Celiac Disease | D002446 | 16 associated lipids |
| Atherosclerosis | D050197 | 85 associated lipids |
| Respiratory Syncytial Virus Infections | D018357 | 10 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
| Gene | Cross reference | Weighted score | Related literatures |
|---|
Xenograft Model are used in the study 'Therapeutic targeting of PELP1 prevents ovarian cancer growth and metastasis.' (Chakravarty D et al., 2011).
Mouse Model are used in the study 'Therapeutic EphA2 gene targeting in vivo using neutral liposomal small interfering RNA delivery.' (Landen CN et al., 2005).
| Model | Cross reference | Weighted score | Related literatures |
|---|
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Ishigami T et al. | Effect of Boundary Edge in DOPC/DPPC/Cholesterol Liposomes on Acceleration of l-Histidine Preferential Adsorption. | 2016 | Langmuir | pmid:27232976 |
| Ngo AT and Cosa G | Assembly of zwitterionic phospholipid/conjugated polyelectrolyte complexes: structure and photophysical properties. | 2010 | Langmuir | pmid:20017509 |
| Ileri Ercan N et al. | Molecular Dynamics Modeling of Methylene Blue-DOPC Lipid Bilayer Interactions. | 2018 | Langmuir | pmid:29553270 |
| Komura S et al. | Tension-induced morphological transition in mixed lipid bilayers. | 2006 | Langmuir | pmid:16863221 |
| Vafaei S et al. | Hybrid Biomimetic Interfaces Integrating Supported Lipid Bilayers with Decellularized Extracellular Matrix Components. | 2018 | Langmuir | pmid:29489371 |
| Rocha S et al. | Probing Microscopic Orientation in Membranes by Linear Dichroism. | 2016 | Langmuir | pmid:26974226 |
| Galluzzi M et al. | Interaction of imidazolium-based room-temperature ionic liquids with DOPC phospholipid monolayers: electrochemical study. | 2013 | Langmuir | pmid:23654287 |
| Jurkiewicz P et al. | Headgroup hydration and mobility of DOTAP/DOPC bilayers: a fluorescence solvent relaxation study. | 2006 | Langmuir | pmid:17014112 |
| Przybylo M et al. | Lipid diffusion in giant unilamellar vesicles is more than 2 times faster than in supported phospholipid bilayers under identical conditions. | 2006 | Langmuir | pmid:17042516 |
| Gao J et al. | Aromaticity/Bulkiness of Surface Ligands to Promote the Interaction of Anionic Amphiphilic Gold Nanoparticles with Lipid Bilayers. | 2016 | Langmuir | pmid:26794292 |
| Galimzyanov TR et al. | Line Activity of Ganglioside GM1 Regulates the Raft Size Distribution in a Cholesterol-Dependent Manner. | 2017 | Langmuir | pmid:28324651 |
| Achilles A et al. | Self-Assembly of X-Shaped Bolapolyphiles in Lipid Membranes: Solid-State NMR Investigations. | 2016 | Langmuir | pmid:26735449 |
| Suga K et al. | Preferential Adsorption of l-Histidine onto DOPC/Sphingomyelin/3β-[N-(N',N'-dimethylaminoethane)carbamoyl]cholesterol Liposomes in the Presence of Chiral Organic Acids. | 2017 | Langmuir | pmid:28272888 |
| Kataoka-Hamai C et al. | Binding of Lipopolysaccharide and Cholesterol-Modified Gelatin on Supported Lipid Bilayers: Effect of Bilayer Area Confinement and Bilayer Edge Tension. | 2016 | Langmuir | pmid:26735125 |
| Schwierz N et al. | Mechanism of Reversible Peptide-Bilayer Attachment: Combined Simulation and Experimental Single-Molecule Study. | 2016 | Langmuir | pmid:26717083 |
| Chen Y et al. | Interactions of Cationic/Anionic Mixed Surfactant Aggregates with Phospholipid Vesicles and Their Skin Penetration Ability. | 2017 | Langmuir | pmid:28013540 |
| Nikolov V et al. | Bias-dependent admittance in hybrid bilayer membranes. | 2006 | Langmuir | pmid:16893210 |
| Macdonald RC et al. | Surface properties of dioleoyl-sn-glycerol-3-ethylphosphocholine, a cationic phosphatidylcholine transfection agent, alone and in combination with lipids or DNA. | 2006 | Langmuir | pmid:16519481 |
| Vermathen M et al. | pH-dependent distribution of chlorin e6 derivatives across phospholipid bilayers probed by NMR spectroscopy. | 2010 | Langmuir | pmid:20420428 |
| Rossetti FF et al. | Asymmetric distribution of phosphatidyl serine in supported phospholipid bilayers on titanium dioxide. | 2006 | Langmuir | pmid:16584212 |
| Richter RP et al. | Formation of solid-supported lipid bilayers: an integrated view. | 2006 | Langmuir | pmid:16584220 |
| Caracciolo G et al. | One-dimensional thermotropic dilatation area of lipid headgroups within lamellar lipid/DNA complexes. | 2006 | Langmuir | pmid:16618174 |
| Kent B et al. | Direct Comparison of Disaccharide Interaction with Lipid Membranes at Reduced Hydrations. | 2015 | Langmuir | pmid:26225718 |
| Folgering JH et al. | Lipid-mediated light activation of a mechanosensitive channel of large conductance. | 2004 | Langmuir | pmid:15301476 |
| Morandat S and El Kirat K | Membrane resistance to Triton X-100 explored by real-time atomic force microscopy. | 2006 | Langmuir | pmid:16768509 |
| Tabaei SR et al. | Solvent-assisted lipid self-assembly at hydrophilic surfaces: factors influencing the formation of supported membranes. | 2015 | Langmuir | pmid:25679066 |
| Carravilla P et al. | Two-photon Laurdan studies of the ternary lipid mixture DOPC:SM:cholesterol reveal a single liquid phase at sphingomyelin:cholesterol ratios lower than 1. | 2015 | Langmuir | pmid:25658036 |
| Inaoka Y and Yamazaki M | Vesicle fission of giant unilamellar vesicles of liquid-ordered-phase membranes induced by amphiphiles with a single long hydrocarbon chain. | 2007 | Langmuir | pmid:17209626 |
| Morandat S and El Kirat K | Real-time atomic force microscopy reveals cytochrome c-induced alterations in neutral lipid bilayers. | 2007 | Langmuir | pmid:17887784 |
| Kucerka N et al. | Curvature effect on the structure of phospholipid bilayers. | 2007 | Langmuir | pmid:17241048 |
| Oh E et al. | Contribution of temperature to deformation of adsorbed vesicles studied by nanoplasmonic biosensing. | 2015 | Langmuir | pmid:25531903 |
| DeWitt BN and Dunn RC | Interaction of cholesterol in ternary lipid mixtures investigated using single-molecule fluorescence. | 2015 | Langmuir | pmid:25531175 |
| Pabst G et al. | Entropy-driven softening of fluid lipid bilayers by alamethicin. | 2007 | Langmuir | pmid:17939689 |
| Lapinski MM et al. | Comparison of liposomes formed by sonication and extrusion: rotational and translational diffusion of an embedded chromophore. | 2007 | Langmuir | pmid:17939695 |
| Fortunelli A and Monti S | Simulations of lipid adsorption on TiO2 surfaces in solution. | 2008 | Langmuir | pmid:18712891 |
| Coban O et al. | Ganglioside partitioning and aggregation in phase-separated monolayers characterized by bodipy GM1 monomer/dimer emission. | 2007 | Langmuir | pmid:17477552 |
| Giocondi MC et al. | Remodeling of ordered membrane domains by GPI-anchored intestinal alkaline phosphatase. | 2007 | Langmuir | pmid:17661499 |
| Hirano A et al. | One-dimensional protein-based nanoparticles induce lipid bilayer disruption: carbon nanotube conjugates and amyloid fibrils. | 2010 | Langmuir | pmid:20964299 |
| Uppamoochikkal P et al. | Orientation of tie-lines in the phase diagram of DOPC/DPPC/cholesterol model biomembranes. | 2010 | Langmuir | pmid:20968281 |
| Filippov AV et al. | Effect of curcumin on lateral diffusion of phosphatidylcholines in saturated and unsaturated bilayers. | 2014 | Langmuir | pmid:25157681 |
| Matson M et al. | Spectral properties and orientation of voltage-sensitive dyes in lipid membranes. | 2012 | Langmuir | pmid:22738247 |
| Zhang S et al. | Freezing or wrapping: the role of particle size in the mechanism of nanoparticle-biomembrane interaction. | 2012 | Langmuir | pmid:22717012 |
| Suga K and Umakoshi H | Detection of nanosized ordered domains in DOPC/DPPC and DOPC/Ch binary lipid mixture systems of large unilamellar vesicles using a TEMPO quenching method. | 2013 | Langmuir | pmid:23506052 |
| Nordlund G et al. | Formation of supported lipid bilayers on silica particles studied using flow cytometry. | 2009 | Langmuir | pmid:19265407 |
| Krishnaswamy R et al. | Aggregation of a peptide antibiotic alamethicin at the air-water interface and its influence on the viscoelasticity of phospholipid monolayers. | 2008 | Langmuir | pmid:18823083 |
| Zidovska A et al. | Block liposomes from curvature-stabilizing lipids: connected nanotubes, -rods, or -spheres. | 2009 | Langmuir | pmid:18834165 |
| Popa R et al. | Entrance effects at nanopores of nanocapsules functionalized with poly(ethylene glycol) and their flow through nanochannels. | 2008 | Langmuir | pmid:18950201 |
| Imam ZI et al. | Steric Pressure among Membrane-Bound Polymers Opposes Lipid Phase Separation. | 2016 | Langmuir | pmid:27043009 |
| Fried ES et al. | Biodegradable, Tethered Lipid Bilayer-Microsphere Systems with Membrane-Integrated α-Helical Peptide Anchors. | 2016 | Langmuir | pmid:26972467 |
| Richter RP et al. | On the effect of the solid support on the interleaflet distribution of lipids in supported lipid bilayers. | 2005 | Langmuir | pmid:15620318 |
| Dabkowska AP et al. | Specular neutron reflectivity studies of the interaction of cytochrome c with supported phosphatidylcholine bilayers doped with phosphatidylserine. | 2009 | Langmuir | pmid:19714900 |
| Orosz KS et al. | Photopolymerization of Dienoyl Lipids Creates Planar Supported Poly(lipid) Membranes with Retained Fluidity. | 2016 | Langmuir | pmid:26794208 |
| Brown AC et al. | Measuring raft size as a function of membrane composition in PC-based systems: Part 1--binary systems. | 2007 | Langmuir | pmid:17887778 |
| Brown AC et al. | Measuring raft size as a function of membrane composition in PC-based systems: Part II--ternary systems. | 2007 | Langmuir | pmid:17887779 |
| Gillams RJ et al. | Formation of inverse topology lyotropic phases in dioleoylphosphatidylcholine/oleic acid and dioleoylphosphatidylethanolamine/oleic acid binary mixtures. | 2014 | Langmuir | pmid:24605989 |
| Buboltz JT et al. | High-resolution mapping of phase behavior in a ternary lipid mixture: do lipid-raft phase boundaries depend on the sample preparation procedure? | 2007 | Langmuir | pmid:17949025 |
| Hochrein MB et al. | Structure and mobility of lipid membranes on a thermoplastic substrate. | 2006 | Langmuir | pmid:16401100 |
| Blanchette CD et al. | Using nucleation rates to determine the interfacial line tension of symmetric and asymmetric lipid bilayer domains. | 2007 | Langmuir | pmid:17451264 |
| Ghosh SK et al. | Structure and Volta potential of lipid multilayers: effect of X-ray irradiation. | 2013 | Langmuir | pmid:23231362 |
| Barriga HM et al. | Buffer-induced swelling and vesicle budding in binary lipid mixtures of dioleoylphosphatidylcholine:dioleoylphosphatidylethanolamine and dioleoylphosphatidylcholine:lysophosphatidylcholine using small-angle X-ray scattering and ³¹P static NMR. | 2015 | Langmuir | pmid:25738977 |
| Pandit SA et al. | Cholesterol packing around lipids with saturated and unsaturated chains: a simulation study. | 2008 | Langmuir | pmid:18517226 |
| Benes M et al. | Surface-dependent transitions during self-assembly of phospholipid membranes on mica, silica, and glass. | 2004 | Langmuir | pmid:15518504 |
| Liu C and Faller R | Conformational, dynamical. and tensional study of tethered bilayer lipid membranes in coarse-grained molecular simulations. | 2012 | Langmuir | pmid:23092246 |
| Hamada T et al. | Reversible photoswitching in a cell-sized vesicle. | 2005 | Langmuir | pmid:16089361 |
| Protopapa E et al. | Interaction of self-assembling beta-sheet peptides with phospholipid monolayers: the role of aggregation state, polarity, charge and applied field. | 2009 | Langmuir | pmid:19437790 |
| Zhang N et al. | Partition of Glutamic Acid-Based Single-Chain and Gemini Amphiphiles into Phospholipid Membranes. | 2018 | Langmuir | pmid:30350992 |
| Yasuda T et al. | Nanosized Phase Segregation of Sphingomyelin and Dihydrosphigomyelin in Unsaturated Phosphatidylcholine Binary Membranes without Cholesterol. | 2018 | Langmuir | pmid:30350701 |
| Liu X | Interactions of Silver Nanoparticles Formed in Situ on AFM Tips with Supported Lipid Bilayers. | 2018 | Langmuir | pmid:30109936 |
| Melby ES et al. | Peripheral Membrane Proteins Facilitate Nanoparticle Binding at Lipid Bilayer Interfaces. | 2018 | Langmuir | pmid:30102857 |
| Richter RP and Brisson A | QCM-D on mica for parallel QCM-D-AFM studies. | 2004 | Langmuir | pmid:15969172 |
| Han CT and Chao L | Using a patterned grating structure to create lipid bilayer platforms insensitive to air bubbles. | 2015 | Lab Chip | pmid:25316602 |
| Elani Y et al. | Novel technologies for the formation of 2-D and 3-D droplet interface bilayer networks. | 2012 | Lab Chip | pmid:22858803 |
| Almela MJ et al. | Inhibitors of poliovirus uncoating efficiently block the early membrane permeabilization induced by virus particles. | 1991 | J. Virol. | pmid:1850030 |
| Ho RJ et al. | Antigen-presenting liposomes are effective in treatment of recurrent herpes simplex virus genitalis in guinea pigs. | 1989 | J. Virol. | pmid:2542605 |
| Dick RA et al. | Hydrodynamic and Membrane Binding Properties of Purified Rous Sarcoma Virus Gag Protein. | 2015 | J. Virol. | pmid:26246573 |
| Zhang H and Cramer WA | Problems in obtaining diffraction-quality crystals of hetero-oligomeric integral membrane proteins. | 2005 | J. Struct. Funct. Genomics | pmid:16211522 |
| Shaw JE et al. | Tracking peptide-membrane interactions: insights from in situ coupled confocal-atomic force microscopy imaging of NAP-22 peptide insertion and assembly. | 2006 | J. Struct. Biol. | pmid:16889981 |
| Owens JM et al. | Two-dimensional crystals of protein kinase C. | 1998 | J. Struct. Biol. | pmid:9573621 |
| Shaw JE et al. | Cationic peptide-induced remodelling of model membranes: direct visualization by in situ atomic force microscopy. | 2008 | J. Struct. Biol. | pmid:18180166 |
| Schwarz D et al. | Direct visualization of a cardiolipin-dependent cytochrome P450scc-induced vesicle aggregation. | 1994 Nov-Dec | J. Struct. Biol. | pmid:7734245 |
| Mechaly AE et al. | Pores of the toxin FraC assemble into 2D hexagonal clusters in both crystal structures and model membranes. | 2012 | J. Struct. Biol. | pmid:22728830 |
| Oreopoulos J and Yip CM | Combinatorial microscopy for the study of protein-membrane interactions in supported lipid bilayers: Order parameter measurements by combined polarized TIRFM/AFM. | 2009 | J. Struct. Biol. | pmid:19268707 |
| Ira S et al. | Enzymatic generation of ceramide induces membrane restructuring: Correlated AFM and fluorescence imaging of supported bilayers. | 2009 | J. Struct. Biol. | pmid:19348948 |
| Le Bihan O et al. | Cryo-electron tomography of nanoparticle transmigration into liposome. | 2009 | J. Struct. Biol. | pmid:19596070 |
| Shenoy SS et al. | Membrane association of the PTEN tumor suppressor: electrostatic interaction with phosphatidylserine-containing bilayers and regulatory role of the C-terminal tail. | 2012 | J. Struct. Biol. | pmid:23073177 |
| Ren G et al. | Polymorphism in the packing of aquaporin-1 tetramers in 2-D crystals. | 2000 | J. Struct. Biol. | pmid:10806090 |
| Tang EK et al. | Metabolism of substrates incorporated into phospholipid vesicles by mouse 25-hydroxyvitamin D3 1alpha-hydroxylase (CYP27B1). | 2010 | J. Steroid Biochem. Mol. Biol. | pmid:20193763 |
| Calori IR and Tedesco AC | Lipid vesicles loading aluminum phthalocyanine chloride: Formulation properties and disaggregation upon intracellular delivery. | 2016 | J. Photochem. Photobiol. B, Biol. | pmid:27130963 |
| Ruan X et al. | Phosphatidylcholine-induced reactivation of photosystem II membranes pretreated with Triton X-100. | 2002 | J. Photochem. Photobiol. B, Biol. | pmid:12031811 |
| Versluis AJ et al. | Interaction between zinc(II)-phthalocyanine-containing liposomes and human low density lipoprotein. | 1994 | J. Photochem. Photobiol. B, Biol. | pmid:8040754 |
| Hostetler KY and Jellison EJ | Inhibition of kidney lysosomal phospholipase A1 by aminoglycosides is a novel variant of substrate depletion inhibition. | 1990 | J. Pharmacol. Exp. Ther. | pmid:2366181 |
| Trudell JR et al. | Antibodies raised against trifluoroacetyl-protein adducts bind to N-trifluoroacetyl-phosphatidylethanolamine in hexagonal phase phospholipid micelles. | 1991 | J. Pharmacol. Exp. Ther. | pmid:2033512 |
| Sarmento AB et al. | Partition of dopamine antagonists into synthetic lipid bilayers: the effect of membrane structure and composition. | 1993 | J. Pharm. Pharmacol. | pmid:8105052 |
| Hesselink RW et al. | Membrane-bound peptides from V-ATPase subunit a do not interact with an indole-type inhibitor. | 2008 | J. Pept. Sci. | pmid:18069732 |
| Fernández-Carneado J et al. | Fatty acyl moieties: improving Pro-rich peptide uptake inside HeLa cells. | 2005 | J. Pept. Res. | pmid:15885117 |
| Moerkerke S et al. | Selective Recognition of Phosphatidylcholine Lipids by a Biomimetic Calix[6]tube Receptor. | 2015 | J. Org. Chem. | pmid:26258943 |
| Vares L et al. | Synthesis and supramolecular properties of conformationally restricted and flexible phospholipids. | 2003 | J. Org. Chem. | pmid:14682702 |
| Peters MW et al. | Lateral distribution of gangliosides in bilayer membranes: lipid and ionic effects. | 1984 | J. Neurosci. Res. | pmid:6548772 |
| Gambale F et al. | GM1 micelles modify the transport properties of the ionophore gramicidin D in artificial planar bilayers. | 1984 | J. Neurosci. Res. | pmid:6209414 |
| Nick AM et al. | Silencing of p130cas in ovarian carcinoma: a novel mechanism for tumor cell death. | 2011 | J. Natl. Cancer Inst. | pmid:21957230 |