1,2-Dioleoyl-sn-Glycero-3-Phosphocholine is a lipid of Glycerophospholipids (GP) class. 1,2-dioleoyl-sn-glycero-3-phosphocholine is associated with abnormalities such as Exanthema, Renal tubular disorder, Nodule, Gigantism and Mycoses. The involved functions are known as Lysis, Encapsulation, Process, Uptake and Flow or discharge. 1,2-dioleoyl-sn-glycero-3-phosphocholine often locates in Cytoplasmic matrix, Endosomes, soluble, Endoplasmic Reticulum and Membrane. The associated genes with 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine are P4HTM gene, synthetic peptide, BCAR1 gene, PCNA gene and CNTNAP1 gene. The related lipids are Liposomes, 1,2-oleoylphosphatidylcholine, 1,2-distearoylphosphatidylethanolamine, Butanols and Cardiolipins. The related experimental models are Mouse Model and Xenograft Model.
To understand associated biological information of 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
1,2-Dioleoyl-sn-Glycero-3-Phosphocholine is suspected in Gigantism, Nodule, protrusion, DERMATITIS HERPETIFORMIS, FAMILIAL, Exanthema, Renal tubular disorder and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Ovarian Neoplasms | D010051 | 10 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Neuroblastoma | D009447 | 66 associated lipids |
| Niemann-Pick Diseases | D009542 | 25 associated lipids |
| Celiac Disease | D002446 | 16 associated lipids |
| Atherosclerosis | D050197 | 85 associated lipids |
| Respiratory Syncytial Virus Infections | D018357 | 10 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
| Gene | Cross reference | Weighted score | Related literatures |
|---|
Xenograft Model are used in the study 'Therapeutic targeting of PELP1 prevents ovarian cancer growth and metastasis.' (Chakravarty D et al., 2011).
Mouse Model are used in the study 'Therapeutic EphA2 gene targeting in vivo using neutral liposomal small interfering RNA delivery.' (Landen CN et al., 2005).
| Model | Cross reference | Weighted score | Related literatures |
|---|
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Un K et al. | Intracellular trafficking mechanism of cationic phospholipids including cationic liposomes in HeLa cells. | 2014 | Pharmazie | pmid:25073398 |
| Sankhagowit S et al. | The dynamics of giant unilamellar vesicle oxidation probed by morphological transitions. | 2014 | Biochim. Biophys. Acta | pmid:24998358 |
| Barry MC et al. | Membrane fouling by vesicles and prevention through ozonation. | 2014 | Environ. Sci. Technol. | pmid:24911399 |
| Paloncýová M et al. | Amphiphilic drug-like molecules accumulate in a membrane below the head group region. | 2014 | J Phys Chem B | pmid:24417480 |
| Andorko JI et al. | Intra-lymph node injection of biodegradable polymer particles. | 2014 | J Vis Exp | pmid:24430972 |
| Pandiscia LA and Schweitzer-Stenner R | Salt as a catalyst in the mitochondria: returning cytochrome c to its native state after it misfolds on the surface of cardiolipin containing membranes. | 2014 | Chem. Commun. (Camb.) | pmid:24394851 |
| Himeno H et al. | Charge-induced phase separation in lipid membranes. | 2014 | Soft Matter | pmid:25154325 |
| Shaikh SR et al. | Increasing mitochondrial membrane phospholipid content lowers the enzymatic activity of electron transport complexes. | 2014 | Biochemistry | pmid:25145682 |
| Shimobayashi SF and Ichikawa M | Emergence of DNA-encapsulating liposomes from a DNA-lipid blend film. | 2014 | J Phys Chem B | pmid:25133311 |
| Murugova TN and Balgavý P | Molecular volumes of DOPC and DOPS in mixed bilayers of multilamellar vesicles. | 2014 | Phys Chem Chem Phys | pmid:25055002 |
| Bowey K et al. | 2-Dioleoyl-sn-glycero-3-phosphocholine-based nanoliposomes as an effective delivery platform for 17β-estradiol. | 2014 | Eur J Pharm Biopharm | pmid:24161656 |
| Filippov AV et al. | Effect of curcumin on lateral diffusion of phosphatidylcholines in saturated and unsaturated bilayers. | 2014 | Langmuir | pmid:25157681 |
| Spillane KM et al. | High-speed single-particle tracking of GM1 in model membranes reveals anomalous diffusion due to interleaflet coupling and molecular pinning. | 2014 | Nano Lett. | pmid:25133992 |
| Furlan G et al. | Phosphatase CD45 both positively and negatively regulates T cell receptor phosphorylation in reconstituted membrane protein clusters. | 2014 | J. Biol. Chem. | pmid:25128530 |
| Cardenas AE and Elber R | Modeling kinetics and equilibrium of membranes with fields: milestoning analysis and implication to permeation. | 2014 | J Chem Phys | pmid:25106564 |
| Drachmann ND et al. | Comparing crystal structures of Ca(2+) -ATPase in the presence of different lipids. | 2014 | FEBS J. | pmid:25103814 |
| Ryu YS et al. | Reconstituting ring-rafts in bud-mimicking topography of model membranes. | 2014 | Nat Commun | pmid:25058275 |
| Fernández ML and Reigada R | Effects of dimethyl sulfoxide on lipid membrane electroporation. | 2014 | J Phys Chem B | pmid:25035931 |
| Barriga HM et al. | Droplet interface bilayer reconstitution and activity measurement of the mechanosensitive channel of large conductance from Escherichia coli. | 2014 | J R Soc Interface | pmid:25008079 |
| Pfeiffer H et al. | FTIR spectroscopy study of the pressure-dependent behaviour of 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC) and 1-palmitoyl-2-oleolyl-sn-glycero-3-phosphocholine (POPC) at low degrees of hydration. | 2013 May-Jun | Chem. Phys. Lipids | pmid:23524282 |
| Darwish TA et al. | Synthesis of deuterated [D32 ]oleic acid and its phospholipid derivative [D64 ]dioleoyl-sn-glycero-3-phosphocholine. | 2013 Jul-Aug | J Labelled Comp Radiopharm | pmid:24285531 |
| Hao C et al. | Mixed monolayers of DOPC and palmitic acid at the liquid-air interface. | 2013 | Colloids Surf B Biointerfaces | pmid:24045147 |
| van Lengerich B et al. | Individual vesicle fusion events mediated by lipid-anchored DNA. | 2013 | Biophys. J. | pmid:23870262 |
| Wang F and Liu J | Nanodiamond decorated liposomes as highly biocompatible delivery vehicles and a comparison with carbon nanotubes and graphene oxide. | 2013 | Nanoscale | pmid:24162019 |
| Chakraborty H et al. | A novel assay for detecting fusion pore formation: implications for the fusion mechanism. | 2013 | Biochemistry | pmid:24164461 |
| Hirtz M et al. | Multiplexed biomimetic lipid membranes on graphene by dip-pen nanolithography. | 2013 | Nat Commun | pmid:24107937 |
| Wang F et al. | Orthogonal adsorption onto nano-graphene oxide using different intermolecular forces for multiplexed delivery. | 2013 | Adv. Mater. Weinheim | pmid:23722422 |
| Vakurov A et al. | ZnO nanoparticle interactions with phospholipid monolayers. | 2013 | J Colloid Interface Sci | pmid:23743048 |
| Galluzzi M et al. | Interaction of imidazolium-based room-temperature ionic liquids with DOPC phospholipid monolayers: electrochemical study. | 2013 | Langmuir | pmid:23654287 |
| Reusch T et al. | Nonequilibrium collective dynamics in photoexcited lipid multilayers by time resolved diffuse x-ray scattering. | 2013 | Phys. Rev. Lett. | pmid:24483815 |
| Mihut AM et al. | Tunable adsorption of soft colloids on model biomembranes. | 2013 | ACS Nano | pmid:24191704 |
| Becucci L et al. | Can proton pumping by SERCA enhance the regulatory role of phospholamban and sarcolipin? | 2013 | Biochim. Biophys. Acta | pmid:23872124 |
| Jang H et al. | Familial Alzheimer's disease Osaka mutant (ΔE22) β-barrels suggest an explanation for the different Aβ1-40/42 preferred conformational states observed by experiment. | 2013 | J Phys Chem B | pmid:24000923 |
| Berka K et al. | Behavior of human cytochromes P450 on lipid membranes. | 2013 | J Phys Chem B | pmid:23987570 |
| Caillon L et al. | Evaluation of membrane models and their composition for islet amyloid polypeptide-membrane aggregation. | 2013 | Biochim. Biophys. Acta | pmid:23707907 |
| Konyakhina TM et al. | Phase diagram of a 4-component lipid mixture: DSPC/DOPC/POPC/chol. | 2013 | Biochim. Biophys. Acta | pmid:23747294 |
| Bruno MJ et al. | Interactions of drugs and amphiphiles with membranes: modulation of lipid bilayer elastic properties by changes in acyl chain unsaturation and protonation. | 2013 | Faraday Discuss. | pmid:23805753 |
| Olsen BN et al. | The structural basis of cholesterol accessibility in membranes. | 2013 | Biophys. J. | pmid:24138860 |
| Suga K and Umakoshi H | Detection of nanosized ordered domains in DOPC/DPPC and DOPC/Ch binary lipid mixture systems of large unilamellar vesicles using a TEMPO quenching method. | 2013 | Langmuir | pmid:23506052 |
| Pyrkova DV et al. | Dynamic clustering of lipids in hydrated two-component membranes: results of computer modeling and putative biological impact. | 2013 | J. Biomol. Struct. Dyn. | pmid:22804614 |
| Ikeuchi R and Iwasaki Y | High mineral affinity of polyphosphoester ionomer-phospholipid vesicles. | 2013 | J Biomed Mater Res A | pmid:22829566 |
| Musgrove A et al. | Potential-dependent interaction of DOPC liposomes with an octadecanol-covered Au(111) surface investigated using electrochemical methods coupled with in situ fluorescence microscopy. | 2013 | Langmuir | pmid:23414099 |
| Hughes ZE et al. | The effects of cryosolvents on DOPC-β-sitosterol bilayers determined from molecular dynamics simulations. | 2013 | J Phys Chem B | pmid:23445456 |
| Levadny V et al. | Rate constant of tension-induced pore formation in lipid membranes. | 2013 | Langmuir | pmid:23472875 |
| Smith E et al. | Kinetic regulation of the binding of prothrombin to phospholipid membranes. | 2013 | Mol. Cell. Biochem. | pmid:23812842 |
| Czogalla A et al. | Switchable domain partitioning and diffusion of DNA origami rods on membranes. | 2013 | Faraday Discuss. | pmid:23805736 |
| Baoukina S et al. | Computer simulations of the phase separation in model membranes. | 2013 | Faraday Discuss. | pmid:23805738 |
| Aberg C et al. | Lipid phase behaviour under steady state conditions. | 2013 | Faraday Discuss. | pmid:23805741 |
| Sanborn J et al. | Transient pearling and vesiculation of membrane tubes under osmotic gradients. | 2013 | Faraday Discuss. | pmid:23805742 |
| Uline MJ and Szleifer I | Mode specific elastic constants for the gel, liquid-ordered, and liquid-disordered phases of DPPC/DOPC/cholesterol model lipid bilayers. | 2013 | Faraday Discuss. | pmid:23805743 |
| Weinberger A et al. | Gel-assisted formation of giant unilamellar vesicles. | 2013 | Biophys. J. | pmid:23823234 |
| Woo Y et al. | Hydrodynamic filtration in microfluidic channels as size-selection process for giant unilamellar vesicles. | 2013 | J Biomed Nanotechnol | pmid:23621019 |
| Chen X et al. | Insertion of TAT peptide and perturbation of negatively charged model phospholipid bilayer revealed by neutron diffraction. | 2013 | Biochim. Biophys. Acta | pmid:23643891 |
| Yi P and Chen KL | Interaction of multiwalled carbon nanotubes with supported lipid bilayers and vesicles as model biological membranes. | 2013 | Environ. Sci. Technol. | pmid:23647313 |
| Takahashi T et al. | Multiple membrane interactions and versatile vesicle deformations elicited by melittin. | 2013 | Toxins (Basel) | pmid:23594437 |
| Suesca E et al. | Sulfocerebrosides upregulate liposome uptake in human astrocytes without inducing a proinflammatory response. | 2013 | Cytometry A | pmid:23671026 |
| Pierrat P et al. | Phospholipid-detergent conjugates as novel tools for siRNA delivery. | 2013 | Chemistry | pmid:23296638 |
| Reigada R | Atomistic study of lipid membranes containing chloroform: looking for a lipid-mediated mechanism of anesthesia. | 2013 | PLoS ONE | pmid:23300982 |
| Fu D et al. | Hyperspectral imaging with stimulated Raman scattering by chirped femtosecond lasers. | 2013 | J Phys Chem B | pmid:23256635 |
| Shimanouchi T et al. | Membrane fusion mediated by phospholipase C under endosomal pH conditions. | 2013 | Colloids Surf B Biointerfaces | pmid:23201722 |
| Ghosh SK et al. | Structure and Volta potential of lipid multilayers: effect of X-ray irradiation. | 2013 | Langmuir | pmid:23231362 |
| MartÃn M and de Mendoza D | Regulation of Bacillus subtilis DesK thermosensor by lipids. | 2013 | Biochem. J. | pmid:23356219 |
| Parra E et al. | Hydrophobic pulmonary surfactant proteins SP-B and SP-C induce pore formation in planar lipid membranes: evidence for proteolipid pores. | 2013 | Biophys. J. | pmid:23332067 |
| Sakamoto S et al. | Investigation of interfacial behavior of glycyrrhizin with a lipid raft model via a Langmuir monolayer study. | 2013 | Biochim. Biophys. Acta | pmid:23333324 |
| Zhao Y et al. | Effects of proteoliposome composition and draw solution types on separation performance of aquaporin-based proteoliposomes: implications for seawater desalination using aquaporin-based biomimetic membranes. | 2013 | Environ. Sci. Technol. | pmid:23311686 |
| Petruzielo RS et al. | Phase behavior and domain size in sphingomyelin-containing lipid bilayers. | 2013 | Biochim. Biophys. Acta | pmid:23337475 |
| Thutupalli S et al. | Why can artificial membranes be fabricated so rapidly in microfluidics? | 2013 | Chem. Commun. (Camb.) | pmid:23321691 |
| Churchman AH et al. | Serum albumin enhances the membrane activity of ZnO nanoparticles. | 2013 | Chem. Commun. (Camb.) | pmid:23321926 |
| Khelashvili G and Harries D | How cholesterol tilt modulates the mechanical properties of saturated and unsaturated lipid membranes. | 2013 | J Phys Chem B | pmid:23323733 |
| Paloncýová M et al. | Molecular insight into affinities of drugs and their metabolites to lipid bilayers. | 2013 | J Phys Chem B | pmid:23387302 |
| Piatkowski L et al. | Probing the distribution of water molecules hydrating lipid membranes with ultrafast Förster vibrational energy transfer. | 2013 | J Phys Chem B | pmid:23360328 |
| Pierrat P et al. | Bioresponsive deciduous-charge amphiphiles for liposomal delivery of DNA and siRNA. | 2013 | Pharm. Res. | pmid:23371513 |
| Karlsson BC et al. | How warfarin's structural diversity influences its phospholipid bilayer membrane permeation. | 2013 | J Phys Chem B | pmid:23373529 |
| Aye M et al. | Genotoxic and mutagenic effects of lipid-coated CdSe/ZnS quantum dots. | 2013 | Mutat. Res. | pmid:23147700 |
| Deleu M et al. | Effects of surfactin on membrane models displaying lipid phase separation. | 2013 | Biochim. Biophys. Acta | pmid:23159483 |
| Puchkov MN et al. | Cytochrome c produces pores in cardiolipin-containing planar bilayer lipid membranes in the presence of hydrogen peroxide. | 2013 | Biochim. Biophys. Acta | pmid:23085196 |
| Kumar S and Miranker AD | A foldamer approach to targeting membrane bound helical states of islet amyloid polypeptide. | 2013 | Chem. Commun. (Camb.) | pmid:23579860 |
| Dengler EC et al. | Mesoporous silica-supported lipid bilayers (protocells) for DNA cargo delivery to the spinal cord. | 2013 | J Control Release | pmid:23517784 |
| Yang Y and McClements DJ | Vitamin E and vitamin E acetate solubilization in mixed micelles: physicochemical basis of bioaccessibility. | 2013 | J Colloid Interface Sci | pmid:23768725 |
| Kapoor S et al. | Pressure modulation of Ras-membrane interactions and intervesicle transfer. | 2013 | J. Am. Chem. Soc. | pmid:23560466 |
| Braun AR et al. | Comparing simulations of lipid bilayers to scattering data: the GROMOS 43A1-S3 force field. | 2013 | J Phys Chem B | pmid:23560979 |
| Bezlyepkina N et al. | Phase diagram and tie-line determination for the ternary mixture DOPC/eSM/cholesterol. | 2013 | Biophys. J. | pmid:23561522 |
| Castillo N et al. | Free energy of WALP23 dimer association in DMPC, DPPC, and DOPC bilayers. | 2013 | Chem. Phys. Lipids | pmid:23415670 |
| Balakrishnan VS et al. | Novicidin's membrane permeabilizing activity is driven by membrane partitioning but not by helicity: a biophysical study of the impact of lipid charge and cholesterol. | 2013 | Biochim. Biophys. Acta | pmid:23562965 |
| Balhara V et al. | Membrane selectivity and biophysical studies of the antimicrobial peptide GL13K. | 2013 | Biochim. Biophys. Acta | pmid:23747365 |
| Katayama S et al. | Effects of pyrenebutyrate on the translocation of arginine-rich cell-penetrating peptides through artificial membranes: recruiting peptides to the membranes, dissipating liquid-ordered phases, and inducing curvature. | 2013 | Biochim. Biophys. Acta | pmid:23711826 |
| Drolle E et al. | Effect of melatonin and cholesterol on the structure of DOPC and DPPC membranes. | 2013 | Biochim. Biophys. Acta | pmid:23714288 |
| Brüning B et al. | Influence of charge density on bilayer bending rigidity in lipid vesicles: a combined dynamic light scattering and neutron spin-echo study. | 2013 | Eur Phys J E Soft Matter | pmid:23884623 |
| Busi E et al. | On the mechanism of ion transport through lipid membranes mediated by PEGylated cyclic oligosaccharides (CyPLOS): an ESR study. | 2013 | Biochim. Biophys. Acta | pmid:23714289 |
| Booker RD and Sum AK | Biophysical changes induced by xenon on phospholipid bilayers. | 2013 | Biochim. Biophys. Acta | pmid:23376329 |
| Gomide AB et al. | Disrupting membrane raft domains by alkylphospholipids. | 2013 | Biochim. Biophys. Acta | pmid:23376656 |
| Nishimura M et al. | Therapeutic synergy between microRNA and siRNA in ovarian cancer treatment. | 2013 | Cancer Discov | pmid:24002999 |
| Torrent M et al. | Ribonucleases as a host-defence family: evidence of evolutionarily conserved antimicrobial activity at the N-terminus. | 2013 | Biochem. J. | pmid:23962023 |
| Thiam AR et al. | COPI buds 60-nm lipid droplets from reconstituted water-phospholipid-triacylglyceride interfaces, suggesting a tension clamp function. | 2013 | Proc. Natl. Acad. Sci. U.S.A. | pmid:23901109 |
| Zhang S et al. | Effect of self-assembly of fullerene nano-particles on lipid membrane. | 2013 | PLoS ONE | pmid:24204827 |
| Pozzi D et al. | Mechanistic understanding of gene delivery mediated by highly efficient multicomponent envelope-type nanoparticle systems. | 2013 | Mol. Pharm. | pmid:24188138 |
| Andrecka J et al. | Direct observation and control of supported lipid bilayer formation with interferometric scattering microscopy. | 2013 | ACS Nano | pmid:24251388 |
| Cicogna F et al. | Interaction of azole compounds with DOPC and DOPC/ergosterol bilayers by spin probe EPR spectroscopy: implications for antifungal activity. | 2013 | J Phys Chem B | pmid:24032998 |
| Krylov NA et al. | Nontrivial behavior of water in the vicinity and inside lipid bilayers as probed by molecular dynamics simulations. | 2013 | ACS Nano | pmid:24070369 |
| Qiao L et al. | Structure and stability studies of mixed monolayers of saturated and unsaturated phospholipids under low-level ozone. | 2013 | Phys Chem Chem Phys | pmid:24042267 |