1,2-Dioleoyl-sn-Glycero-3-Phosphocholine is a lipid of Glycerophospholipids (GP) class. 1,2-dioleoyl-sn-glycero-3-phosphocholine is associated with abnormalities such as Exanthema, Renal tubular disorder, Nodule, Gigantism and Mycoses. The involved functions are known as Lysis, Encapsulation, Process, Uptake and Flow or discharge. 1,2-dioleoyl-sn-glycero-3-phosphocholine often locates in Cytoplasmic matrix, Endosomes, soluble, Endoplasmic Reticulum and Membrane. The associated genes with 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine are P4HTM gene, synthetic peptide, BCAR1 gene, PCNA gene and CNTNAP1 gene. The related lipids are Liposomes, 1,2-oleoylphosphatidylcholine, 1,2-distearoylphosphatidylethanolamine, Butanols and Cardiolipins. The related experimental models are Mouse Model and Xenograft Model.
To understand associated biological information of 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
1,2-Dioleoyl-sn-Glycero-3-Phosphocholine is suspected in Gigantism, Nodule, protrusion, DERMATITIS HERPETIFORMIS, FAMILIAL, Exanthema, Renal tubular disorder and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Ovarian Neoplasms | D010051 | 10 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Neuroblastoma | D009447 | 66 associated lipids |
| Niemann-Pick Diseases | D009542 | 25 associated lipids |
| Celiac Disease | D002446 | 16 associated lipids |
| Atherosclerosis | D050197 | 85 associated lipids |
| Respiratory Syncytial Virus Infections | D018357 | 10 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
| Gene | Cross reference | Weighted score | Related literatures |
|---|
Xenograft Model are used in the study 'Therapeutic targeting of PELP1 prevents ovarian cancer growth and metastasis.' (Chakravarty D et al., 2011).
Mouse Model are used in the study 'Therapeutic EphA2 gene targeting in vivo using neutral liposomal small interfering RNA delivery.' (Landen CN et al., 2005).
| Model | Cross reference | Weighted score | Related literatures |
|---|
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Hayes ME et al. | Assembly of nucleic acid-lipid nanoparticles from aqueous-organic monophases. | 2006 | Biochim. Biophys. Acta | pmid:16678786 |
| Ganchev DN et al. | Size and orientation of the lipid II headgroup as revealed by AFM imaging. | 2006 | Biochemistry | pmid:16681392 |
| Devanathan S et al. | Effects of sphingomyelin, cholesterol and zinc ions on the binding, insertion and aggregation of the amyloid Abeta(1-40) peptide in solid-supported lipid bilayers. | 2006 | FEBS J. | pmid:16689927 |
| Kahya N | Targeting membrane proteins to liquid-ordered phases: molecular self-organization explored by fluorescence correlation spectroscopy. | 2006 | Chem. Phys. Lipids | pmid:16696961 |
| Ringstad L et al. | Effect of peptide length on the interaction between consensus peptides and DOPC/DOPA bilayers. | 2006 | Langmuir | pmid:16700592 |
| Park JW and Lee GU | Properties of mixed lipid monolayers assembled on hydrophobic surfaces through vesicle adsorption. | 2006 | Langmuir | pmid:16700594 |
| Micelli S et al. | Effect of pH-variation on insertion and ion channel formation of human calcitonin into planar lipid bilayers. | 2006 | Front. Biosci. | pmid:16720289 |
| Pereira-Lachataignerais J et al. | Effect of sodium dodecyl sulfate at different hydration conditions on dioleoyl phosphatidylcholine bilayers studied by grazing incidence X-ray diffraction. | 2006 | Langmuir | pmid:16732649 |
| Caesar CE et al. | Membrane interactions of cell-penetrating peptides probed by tryptophan fluorescence and dichroism techniques: correlations of structure to cellular uptake. | 2006 | Biochemistry | pmid:16768464 |
| Morandat S and El Kirat K | Membrane resistance to Triton X-100 explored by real-time atomic force microscopy. | 2006 | Langmuir | pmid:16768509 |
| Higgins MJ et al. | Structured water layers adjacent to biological membranes. | 2006 | Biophys. J. | pmid:16798815 |
| Protopapa E et al. | Electrochemical screening of self-assembling beta-sheet peptides using supported phospholipid monolayers. | 2006 | Med Eng Phys | pmid:16807052 |
| Shahedi V et al. | Domain-formation in DOPC/SM bilayers studied by pfg-NMR: effect of sterol structure. | 2006 | Biophys. J. | pmid:16829566 |
| Zhang J et al. | Lipid peroxidation inhibition capacity assay for antioxidants based on liposomal membranes. | 2006 | Mol Nutr Food Res | pmid:16835871 |
| Dixit SS et al. | Glass bead probes of local structural and mechanical properties of fluid, supported membranes. | 2006 | Chemphyschem | pmid:16847842 |
| Pérez S et al. | Influence of the saturation chain and head group charge of phospholipids in the interaction of hepatitis G virus synthetic peptides. | 2005 | J Phys Chem B | pmid:16853582 |
| Garcia MT et al. | Transdermal delivery of ketoprofen: the influence of drug-dioleylphosphatidylcholine interactions. | 2006 | Pharm. Res. | pmid:16858649 |
| Komura S et al. | Tension-induced morphological transition in mixed lipid bilayers. | 2006 | Langmuir | pmid:16863221 |
| Nicolini C et al. | Pressure tuning of the morphology of heterogeneous lipid vesicles: a two-photon-excitation fluorescence microscopy study. | 2006 | Biophys. J. | pmid:16877511 |
| Vemparala S et al. | Partitioning of anesthetics into a lipid bilayer and their interaction with membrane-bound peptide bundles. | 2006 | Biophys. J. | pmid:16877515 |
| Shaw JE et al. | Tracking peptide-membrane interactions: insights from in situ coupled confocal-atomic force microscopy imaging of NAP-22 peptide insertion and assembly. | 2006 | J. Struct. Biol. | pmid:16889981 |
| Nikolov V et al. | Bias-dependent admittance in hybrid bilayer membranes. | 2006 | Langmuir | pmid:16893210 |
| Jordi W et al. | Phenethyl alcohol disorders phospholipid acyl chains and promotes translocation of the mitochondrial precursor protein apocytochrome c across a lipid bilayer. | 1990 | FEBS Lett. | pmid:1689674 |
| Halder J et al. | Focal adhesion kinase targeting using in vivo short interfering RNA delivery in neutral liposomes for ovarian carcinoma therapy. | 2006 | Clin. Cancer Res. | pmid:16914580 |
| Mukherjee S et al. | Membrane localization and dynamics of Nile Red: effect of cholesterol. | 2007 | Biochim. Biophys. Acta | pmid:16934217 |
| Massey JB and Pownall HJ | Structures of biologically active oxysterols determine their differential effects on phospholipid membranes. | 2006 | Biochemistry | pmid:16939227 |
| Benz RW et al. | Diffraction-based density restraints for membrane and membrane-peptide molecular dynamics simulations. | 2006 | Biophys. J. | pmid:16950837 |
| Buffy JJ et al. | Two-dimensional solid-state NMR reveals two topologies of sarcolipin in oriented lipid bilayers. | 2006 | Biochemistry | pmid:16953579 |
| Bhide SY and Berkowitz ML | The behavior of reorientational correlation functions of water at the water-lipid bilayer interface. | 2006 | J Chem Phys | pmid:16965111 |
| Koynova R et al. | An intracellular lamellar-nonlamellar phase transition rationalizes the superior performance of some cationic lipid transfection agents. | 2006 | Proc. Natl. Acad. Sci. U.S.A. | pmid:16983097 |
| Li L and Cheng JX | Coexisting stripe- and patch-shaped domains in giant unilamellar vesicles. | 2006 | Biochemistry | pmid:17002282 |
| Fa N et al. | Effect of the antibiotic azithromycin on thermotropic behavior of DOPC or DPPC bilayers. | 2006 | Chem. Phys. Lipids | pmid:17007828 |
| Tournois H et al. | Gramicidin A induced fusion of large unilamellar dioleoylphosphatidylcholine vesicles and its relation to the induction of type II nonbilayer structures. | 1990 | Biochemistry | pmid:1701325 |
| Jurkiewicz P et al. | Headgroup hydration and mobility of DOTAP/DOPC bilayers: a fluorescence solvent relaxation study. | 2006 | Langmuir | pmid:17014112 |
| Przybylo M et al. | Lipid diffusion in giant unilamellar vesicles is more than 2 times faster than in supported phospholipid bilayers under identical conditions. | 2006 | Langmuir | pmid:17042516 |
| Feigenson GW | Phase behavior of lipid mixtures. | 2006 | Nat. Chem. Biol. | pmid:17051225 |
| Chiantia S et al. | Combined AFM and two-focus SFCS study of raft-exhibiting model membranes. | 2006 | Chemphyschem | pmid:17051578 |
| Choucair A et al. | Preferential accumulation of Abeta(1-42) on gel phase domains of lipid bilayers: an AFM and fluorescence study. | 2007 | Biochim. Biophys. Acta | pmid:17052685 |
| Yan W and Hall SB | Distribution of coexisting solid and fluid phases alters the kinetics of collapse from phospholipid monolayers. | 2006 | J Phys Chem B | pmid:17078641 |
| Landen CN et al. | Intraperitoneal delivery of liposomal siRNA for therapy of advanced ovarian cancer. | 2006 | Cancer Biol. Ther. | pmid:17106249 |
| Yamada A et al. | Spontaneous transfer of phospholipid-coated oil-in-oil and water-in-oil micro-droplets through an oil/water interface. | 2006 | Langmuir | pmid:17106968 |
| Garg S et al. | Domain registration in raft-mimicking lipid mixtures studied using polymer-tethered lipid bilayers. | 2007 | Biophys. J. | pmid:17114215 |
| Raghuraman H and Chattopadhyay A | Orientation and dynamics of melittin in membranes of varying composition utilizing NBD fluorescence. | 2007 | Biophys. J. | pmid:17114219 |
| Nazarov PV et al. | FRET study of membrane proteins: determination of the tilt and orientation of the N-terminal domain of M13 major coat protein. | 2007 | Biophys. J. | pmid:17114224 |
| Voszka I et al. | Interaction of photosensitizers with liposomes containing unsaturated lipid. | 2007 | Chem. Phys. Lipids | pmid:17118350 |
| Castro-Román F et al. | Investigation of finite system-size effects in molecular dynamics simulations of lipid bilayers. | 2006 | J Phys Chem B | pmid:17125387 |
| Mojzisova H et al. | The pH-dependent distribution of the photosensitizer chlorin e6 among plasma proteins and membranes: a physico-chemical approach. | 2007 | Biochim. Biophys. Acta | pmid:17141733 |
| van den Bogaart G et al. | On the decrease in lateral mobility of phospholipids by sugars. | 2007 | Biophys. J. | pmid:17142271 |
| Morandat S and El Kirat K | Solubilization of supported lipid membranes by octyl glucoside observed by time-lapse atomic force microscopy. | 2007 | Colloids Surf B Biointerfaces | pmid:17207975 |
| Inaoka Y and Yamazaki M | Vesicle fission of giant unilamellar vesicles of liquid-ordered-phase membranes induced by amphiphiles with a single long hydrocarbon chain. | 2007 | Langmuir | pmid:17209626 |
| Kucerka N et al. | Curvature effect on the structure of phospholipid bilayers. | 2007 | Langmuir | pmid:17241048 |
| Ishitsuka R and Kobayashi T | Cholesterol and lipid/protein ratio control the oligomerization of a sphingomyelin-specific toxin, lysenin. | 2007 | Biochemistry | pmid:17243772 |
| Christ K et al. | The role of lipid II in membrane binding of and pore formation by nisin analyzed by two combined biosensor techniques. | 2007 | Biochim. Biophys. Acta | pmid:17254547 |
| Lenhert S et al. | Massively parallel dip-pen nanolithography of heterogeneous supported phospholipid multilayer patterns. | 2007 | Small | pmid:17294472 |
| Ristori S et al. | Synthesis and liposome insertion of a new poly(carboranylalkylthio)porphyrazine to improve potentiality in multiple-approach cancer therapy. | 2007 | J. Am. Chem. Soc. | pmid:17298062 |
| Habiger RG et al. | Influence of stigmastanol and stigmastanyl-phosphorylcholine, two plasma cholesterol lowering substances, on synthetic phospholipid membranes. A 2H- and 31P-NMR study. | 1992 | Biochim. Biophys. Acta | pmid:1730022 |
| Mogensen JE et al. | The major allergen from birch tree pollen, Bet v 1, binds and permeabilizes membranes. | 2007 | Biochemistry | pmid:17311414 |
| Lamparski H et al. | Photoinduced destabilization of liposomes. | 1992 | Biochemistry | pmid:1731924 |
| Wacklin HP et al. | Distribution of reaction products in phospholipase A2 hydrolysis. | 2007 | Biochim. Biophys. Acta | pmid:17355873 |
| Bavdek A et al. | Sterol and pH interdependence in the binding, oligomerization, and pore formation of Listeriolysin O. | 2007 | Biochemistry | pmid:17358050 |
| Weinreb G and Lentz BR | Analysis of membrane fusion as a two-state sequential process: evaluation of the stalk model. | 2007 | Biophys. J. | pmid:17369418 |
| Cicuta P et al. | Diffusion of liquid domains in lipid bilayer membranes. | 2007 | J Phys Chem B | pmid:17388499 |
| Tchoreloff P et al. | A structural study of interfacial phospholipid and lung surfactant layers by transmission electron microscopy after Blodgett sampling: influence of surface pressure and temperature. | 1991 | Chem. Phys. Lipids | pmid:1742808 |
| Erbe A and Sigel R | Tilt angle of lipid acyl chains in unilamellar vesicles determined by ellipsometric light scattering. | 2007 | Eur Phys J E Soft Matter | pmid:17431539 |
| de Almeida RF et al. | Complexity of lipid domains and rafts in giant unilamellar vesicles revealed by combining imaging and microscopic and macroscopic time-resolved fluorescence. | 2007 | Biophys. J. | pmid:17449668 |
| Blanchette CD et al. | Using nucleation rates to determine the interfacial line tension of symmetric and asymmetric lipid bilayer domains. | 2007 | Langmuir | pmid:17451264 |
| Claessens MM et al. | Entropic stabilization and equilibrium size of lipid vesicles. | 2007 | Langmuir | pmid:17461604 |
| O'Connell RJ et al. | Gating and conductance changes in BK(Ca) channels in bilayers are reciprocal. | 2006 | J. Membr. Biol. | pmid:17468961 |
| Hathcock J et al. | Lipid-bound factor Xa regulates tissue factor activity. | 2007 | Biochemistry | pmid:17469850 |
| Coban O et al. | Ganglioside partitioning and aggregation in phase-separated monolayers characterized by bodipy GM1 monomer/dimer emission. | 2007 | Langmuir | pmid:17477552 |
| Cambrea LR et al. | Effect of ions on the organization of phosphatidylcholine/phosphatidic acid bilayers. | 2007 | Biophys. J. | pmid:17483164 |
| Gudheti MV et al. | Imaging and shape analysis of GUVs as model plasma membranes: effect of trans DOPC on membrane properties. | 2007 | Biophys. J. | pmid:17513374 |
| Garner AE et al. | Sphingomyelin chain length influences the distribution of GPI-anchored proteins in rafts in supported lipid bilayers. | 2007 May-Jun | Mol. Membr. Biol. | pmid:17520480 |
| Fa N et al. | Decrease of elastic moduli of DOPC bilayers induced by a macrolide antibiotic, azithromycin. | 2007 | Biochim. Biophys. Acta | pmid:17537401 |
| Wacklin HP and Thomas RK | Spontaneous formation of asymmetric lipid bilayers by adsorption of vesicles. | 2007 | Langmuir | pmid:17539662 |
| Chiantia S et al. | Raft domain reorganization driven by short- and long-chain ceramide: a combined AFM and FCS study. | 2007 | Langmuir | pmid:17564472 |
| Coll EP et al. | The distribution and conformation of very long-chain plant wax components in a lipid bilayer. | 2007 | J Phys Chem B | pmid:17608528 |
| Hughes E et al. | Solid-state NMR and functional measurements indicate that the conserved tyrosine residues of sarcolipin are involved directly in the inhibition of SERCA1. | 2007 | J. Biol. Chem. | pmid:17616528 |
| Stengel G et al. | DNA-induced programmable fusion of phospholipid vesicles. | 2007 | J. Am. Chem. Soc. | pmid:17629277 |
| Gawrisch K and Janz S | The uptake of pristane (2,6,10,14-tetramethylpentadecane) into phospholipid bilayers as assessed by NMR, DSC, and tritium labeling methods. | 1991 | Biochim. Biophys. Acta | pmid:1764453 |
| Esposito C et al. | Flicker spectroscopy of thermal lipid bilayer domain boundary fluctuations. | 2007 | Biophys. J. | pmid:17644560 |
| Quemeneur F et al. | Large and giant vesicles "decorated" with chitosan: effects of pH, salt or glucose stress, and surface adhesion. | 2007 | Biomacromolecules | pmid:17658883 |
| Giocondi MC et al. | Remodeling of ordered membrane domains by GPI-anchored intestinal alkaline phosphatase. | 2007 | Langmuir | pmid:17661499 |
| Hendrich AB et al. | Phase separation is induced by phenothiazine derivatives in phospholipid/sphingomyelin/cholesterol mixtures containing low levels of cholesterol and sphingomyelin. | 2007 | Biophys. Chem. | pmid:17662517 |
| Trépout S et al. | Organization of reconstituted lipoprotein MexA onto supported lipid membrane. | 2007 | Eur. Biophys. J. | pmid:17665187 |
| Ghalit N et al. | Synthesis of bicyclic alkene-/alkane-bridged nisin mimics by ring-closing metathesis and their biochemical evaluation as lipid II binders: toward the design of potential novel antibiotics. | 2007 | Chembiochem | pmid:17674393 |
| Tian A et al. | Line tension at fluid membrane domain boundaries measured by micropipette aspiration. | 2007 | Phys. Rev. Lett. | pmid:17677743 |
| Hac-Wydro K et al. | The influence of phospholipid structure on the interactions with nystatin, a polyene antifungal antibiotic A Langmuir monolayer study. | 2007 | Chem. Phys. Lipids | pmid:17681287 |
| Shinada M et al. | In vitro interaction of selected phospholipid species with mercuric chloride using Fourier transform 1H-NMR. | 1991 | Bull Environ Contam Toxicol | pmid:1768947 |
| Tejwani RW and Anderson BD | Influence of intravesicular pH drift and membrane binding on the liposomal release of a model amine-containing permeant. | 2008 | J Pharm Sci | pmid:17694543 |
| Salvati A et al. | Small angle scattering and zeta potential of liposomes loaded with octa(carboranyl)porphyrazine. | 2007 | J Phys Chem B | pmid:17696389 |
| Lee JY and Schick M | Dependence of the energies of fusion on the intermembrane separation: optimal and constrained. | 2007 | J Chem Phys | pmid:17718633 |
| Traaseth NJ et al. | Spectroscopic validation of the pentameric structure of phospholamban. | 2007 | Proc. Natl. Acad. Sci. U.S.A. | pmid:17804809 |
| Zhao J et al. | Phase studies of model biomembranes: complex behavior of DSPC/DOPC/cholesterol. | 2007 | Biochim. Biophys. Acta | pmid:17825247 |
| Pan J et al. | Temperature dependence of structure, bending rigidity, and bilayer interactions of dioleoylphosphatidylcholine bilayers. | 2008 | Biophys. J. | pmid:17827241 |
| Spurlin TA and Gewirth AA | Charge dependence of a nanoscale supercrystal phase in a supported lipid bilayer. | 2007 | J. Am. Chem. Soc. | pmid:17845046 |
| Anton N et al. | The influence of headgroup structure and fatty acyl chain saturation of phospholipids on monolayer behavior: a comparative rheological study. | 2007 | Chem. Phys. Lipids | pmid:17868664 |
| Yang L et al. | Synthetic antimicrobial oligomers induce a composition-dependent topological transition in membranes. | 2007 | J. Am. Chem. Soc. | pmid:17880067 |
| Brown AC et al. | Measuring raft size as a function of membrane composition in PC-based systems: Part 1--binary systems. | 2007 | Langmuir | pmid:17887778 |
| Brown AC et al. | Measuring raft size as a function of membrane composition in PC-based systems: Part II--ternary systems. | 2007 | Langmuir | pmid:17887779 |