1,2-Dioleoyl-sn-Glycero-3-Phosphocholine

1,2-Dioleoyl-sn-Glycero-3-Phosphocholine is a lipid of Glycerophospholipids (GP) class. 1,2-dioleoyl-sn-glycero-3-phosphocholine is associated with abnormalities such as Exanthema, Renal tubular disorder, Nodule, Gigantism and Mycoses. The involved functions are known as Lysis, Encapsulation, Process, Uptake and Flow or discharge. 1,2-dioleoyl-sn-glycero-3-phosphocholine often locates in Cytoplasmic matrix, Endosomes, soluble, Endoplasmic Reticulum and Membrane. The associated genes with 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine are P4HTM gene, synthetic peptide, BCAR1 gene, PCNA gene and CNTNAP1 gene. The related lipids are Liposomes, 1,2-oleoylphosphatidylcholine, 1,2-distearoylphosphatidylethanolamine, Butanols and Cardiolipins. The related experimental models are Mouse Model and Xenograft Model.

Cross Reference

Introduction

To understand associated biological information of 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine?

1,2-Dioleoyl-sn-Glycero-3-Phosphocholine is suspected in Gigantism, Nodule, protrusion, DERMATITIS HERPETIFORMIS, FAMILIAL, Exanthema, Renal tubular disorder and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Ovarian Neoplasms D010051 10 associated lipids
Edema D004487 152 associated lipids
Neuroblastoma D009447 66 associated lipids
Niemann-Pick Diseases D009542 25 associated lipids
Celiac Disease D002446 16 associated lipids
Atherosclerosis D050197 85 associated lipids
Respiratory Syncytial Virus Infections D018357 10 associated lipids
Total 8

PubChem Associated disorders and diseases

What pathways are associated with 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine?

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What functions are associated with 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine?

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What genes are associated with 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine?

Xenograft Model

Xenograft Model are used in the study 'Therapeutic targeting of PELP1 prevents ovarian cancer growth and metastasis.' (Chakravarty D et al., 2011).

Mouse Model

Mouse Model are used in the study 'Therapeutic EphA2 gene targeting in vivo using neutral liposomal small interfering RNA delivery.' (Landen CN et al., 2005).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine

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Authors Title Published Journal PubMed Link
Antúnez LR et al. Physiochemical Properties of Aluminum Adjuvants Elicit Differing Reorganization of Phospholipid Domains in Model Membranes. 2016 Mol. Pharm. pmid:26998680
Rodríguez G et al. A unique bicellar nanosystem combining two effects on stratum corneum lipids. 2012 Mol. Pharm. pmid:22264106
Cardarelli F et al. Cholesterol-dependent macropinocytosis and endosomal escape control the transfection efficiency of lipoplexes in CHO living cells. 2012 Mol. Pharm. pmid:22196199
Onuki Y et al. Membrane Microdomain Structures of Liposomes and Their Contribution to the Cellular Uptake Efficiency into HeLa Cells. 2016 Mol. Pharm. pmid:26709741
Pozzi D et al. Mechanistic understanding of gene delivery mediated by highly efficient multicomponent envelope-type nanoparticle systems. 2013 Mol. Pharm. pmid:24188138
Owen DM et al. High plasma membrane lipid order imaged at the immunological synapse periphery in live T cells. 2010 Mol. Membr. Biol. pmid:20540668
Bradshaw JP et al. A combined X-ray and neutron diffraction study of selectively deuterated melittin in phospholipid bilayers: effect of pH. 1994 Apr-Jun Mol. Membr. Biol. pmid:7920866
Garner AE et al. Sphingomyelin chain length influences the distribution of GPI-anchored proteins in rafts in supported lipid bilayers. 2007 May-Jun Mol. Membr. Biol. pmid:17520480
Wesołowska O et al. Direct visualization of phase separation induced by phenothiazine-type antipsychotic drugs in model lipid membranes. 2011 Mol. Membr. Biol. pmid:21190429
Prades J et al. Effect of a 2-hydroxylated fatty acid on cholesterol-rich membrane domains. 2012 Mol. Membr. Biol. pmid:22830943
Maggio B Control by ganglioside GD1a of phospholipase A2 activity through modulation of the lamellar-hexagonal (HII) phase transition. 1996 Apr-Jun Mol. Membr. Biol. pmid:8839455
Grasso P et al. Reconstitution of hormone-responsive detergent-solubilized follicle stimulating hormone receptors into liposomes. 1988 Mol. Endocrinol. pmid:3138532
Smith E et al. Kinetic regulation of the binding of prothrombin to phospholipid membranes. 2013 Mol. Cell. Biochem. pmid:23812842
Ghosh B et al. Solubilization, purification, and reconstitution of alpha 2 beta 1 isozyme of Na+/K+ -ATPase from caveolae of pulmonary smooth muscle plasma membrane: comparative studies with DHPC, C12E8, and Triton X-100. 2009 Mol. Cell. Biochem. pmid:19101784
Wagner MJ et al. Preclinical Mammalian Safety Studies of EPHARNA (DOPC Nanoliposomal EphA2-Targeted siRNA). 2017 Mol. Cancer Ther. pmid:28265009
Riley DE and Krieger JN Rapid and practical DNA isolation from Trichomonas vaginalis and other nuclease-rich protozoa. 1992 Mol. Biochem. Parasitol. pmid:1565132
Zhang J et al. Lipid peroxidation inhibition capacity assay for antioxidants based on liposomal membranes. 2006 Mol Nutr Food Res pmid:16835871
Drachmann ND and Olesen C Lipid Exchange by Ultracentrifugation. 2016 Methods Mol. Biol. pmid:26695050
Yesylevskyy SO and Demchenko AP Cholesterol behavior in asymmetric lipid bilayers: insights from molecular dynamics simulations. 2015 Methods Mol. Biol. pmid:25331142
Hu PC and Malmstadt N Asymmetric giant lipid vesicle fabrication. 2015 Methods Mol. Biol. pmid:25331129
Lee OS and Schatz GC Computational simulations of the interaction of lipid membranes with DNA-functionalized gold nanoparticles. 2011 Methods Mol. Biol. pmid:21424456
Bacia K and Schwille P Fluorescence correlation spectroscopy. 2007 Methods Mol. Biol. pmid:18214375
Orädd G and Lindblom G Lateral diffusion coefficients of raft lipids from pulsed field gradient NMR. 2007 Methods Mol. Biol. pmid:18214378
Salamon Z et al. Plasmon-waveguide resonance spectroscopy studies of lateral segregation in solid-supported proteolipid bilayers. 2007 Methods Mol. Biol. pmid:18214380
McIntosh TJ X-ray diffraction to determine the thickness of raft and nonraft bilayers. 2007 Methods Mol. Biol. pmid:18214383
Pencer J et al. Small-angle neutron scattering to detect rafts and lipid domains. 2007 Methods Mol. Biol. pmid:18214384
Burns AR Atomic force microscopy of lipid domains in supported model membranes. 2007 Methods Mol. Biol. pmid:18214386
Pezzoli D et al. Characterization and Investigation of Redox-Sensitive Liposomes for Gene Delivery. 2016 Methods Mol. Biol. pmid:27436322
Myers RL and Chiu IM Single primer-mediated polymerase chain reaction. 1994 Methods Mol. Biol. pmid:7522831
Mangala LS et al. Liposomal siRNA for ovarian cancer. 2009 Methods Mol. Biol. pmid:19495686
Tsuchiya M et al. Antioxidant activity of alpha-tocopherol, beta-carotene, and ubiquinol in membranes: cis-parinaric acid-incorporated liposomes. 1994 Meth. Enzymol. pmid:7808309
Marcocci L et al. Antioxidant activity of nitecapone and its analog OR-1246: effect of structural modification on antioxidant action. 1994 Meth. Enzymol. pmid:7808329
Tsuchiya M et al. Antioxidant radical-scavenging activity of carotenoids and retinoids compared to alpha-tocopherol. 1992 Meth. Enzymol. pmid:1435314
Siwak DR et al. Liposomal antisense oligonucleotides for cancer therapy. 2004 Meth. Enzymol. pmid:15172168
Hostetler KY and Gardner MF Purification of rat kidney lysosomal phospholipase A1. 1991 Meth. Enzymol. pmid:2051928
Yoshikami S and Nöll GN Technique for introducing retinol analogs into the isolated retina. 1982 Meth. Enzymol. pmid:7098891
Shayman JA and Abe A 1-O-acylceramide synthase. 2000 Meth. Enzymol. pmid:10563315
Zidovska A et al. Block liposomes vesicles of charged lipids with distinctly shaped nanoscale sphere-, pear-, tube-, or rod-segments. 2009 Meth. Enzymol. pmid:19913164
Protopapa E et al. Electrochemical screening of self-assembling beta-sheet peptides using supported phospholipid monolayers. 2006 Med Eng Phys pmid:16807052
Han WB et al. Molecular dynamics simulation of interlayer water embedded in phospholipid bilayer. 2014 Mater Sci Eng C Mater Biol Appl pmid:24433886
García-Linares S et al. The effect of cholesterol on the long-range network of interactions established among sea anemone Sticholysin II residues at the water-membrane interface. 2015 Mar Drugs pmid:25815890
Orädd G and Lindblom G Lateral diffusion studied by pulsed field gradient NMR on oriented lipid membranes. 2004 Magn Reson Chem pmid:14745791
Pierrat P et al. DOPC-Detergent Conjugates: Fusogenic Carriers for Improved In Vitro and In Vivo Gene Delivery. 2016 Macromol Biosci pmid:26990218
Lin JT et al. Biosynthesis of triacylglycerols containing ricinoleate in castor microsomes using 1-acyl-2-oleoyl-sn-glycero-3-phosphocholine as the substrate of oleoyl-12-hydroxylase. 1998 Lipids pmid:9470174
Rouet-Mayer MA et al. Critical analysis of phospholipid hydrolyzing activities in ripening tomato fruits. Study by spectrofluorimetry and high-performance liquid chromatography. 1995 Lipids pmid:7475990
Sleight RG and Dao HN Synergistic activation of CTP:phosphocholine cytidylyltransferase by phosphatidylethanolamine and oleic acid. 1990 Lipids pmid:2158609
Van Bambeke F et al. Biophysical studies and intracellular destabilization of pH-sensitive liposomes. 2000 Lipids pmid:10757553
De Oliveira MC et al. Improvement of in vivo stability of phosphodiester oligonucleotide using anionic liposomes in mice. 2000 Life Sci. pmid:10983856
Orosz KS et al. Photopolymerization of Dienoyl Lipids Creates Planar Supported Poly(lipid) Membranes with Retained Fluidity. 2016 Langmuir pmid:26794208
Hamada T et al. Reversible photoswitching in a cell-sized vesicle. 2005 Langmuir pmid:16089361