1,2-Dioleoyl-sn-Glycero-3-Phosphocholine is a lipid of Glycerophospholipids (GP) class. 1,2-dioleoyl-sn-glycero-3-phosphocholine is associated with abnormalities such as Exanthema, Renal tubular disorder, Nodule, Gigantism and Mycoses. The involved functions are known as Lysis, Encapsulation, Process, Uptake and Flow or discharge. 1,2-dioleoyl-sn-glycero-3-phosphocholine often locates in Cytoplasmic matrix, Endosomes, soluble, Endoplasmic Reticulum and Membrane. The associated genes with 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine are P4HTM gene, synthetic peptide, BCAR1 gene, PCNA gene and CNTNAP1 gene. The related lipids are Liposomes, 1,2-oleoylphosphatidylcholine, 1,2-distearoylphosphatidylethanolamine, Butanols and Cardiolipins. The related experimental models are Mouse Model and Xenograft Model.
To understand associated biological information of 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
1,2-Dioleoyl-sn-Glycero-3-Phosphocholine is suspected in Gigantism, Nodule, protrusion, DERMATITIS HERPETIFORMIS, FAMILIAL, Exanthema, Renal tubular disorder and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Ovarian Neoplasms | D010051 | 10 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Neuroblastoma | D009447 | 66 associated lipids |
| Niemann-Pick Diseases | D009542 | 25 associated lipids |
| Celiac Disease | D002446 | 16 associated lipids |
| Atherosclerosis | D050197 | 85 associated lipids |
| Respiratory Syncytial Virus Infections | D018357 | 10 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
| Gene | Cross reference | Weighted score | Related literatures |
|---|
Xenograft Model are used in the study 'Therapeutic targeting of PELP1 prevents ovarian cancer growth and metastasis.' (Chakravarty D et al., 2011).
Mouse Model are used in the study 'Therapeutic EphA2 gene targeting in vivo using neutral liposomal small interfering RNA delivery.' (Landen CN et al., 2005).
| Model | Cross reference | Weighted score | Related literatures |
|---|
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Lee BL et al. | Permeation of the three aromatic dipeptides through lipid bilayers: Experimental and computational study. | 2016 | J Chem Phys | pmid:27369545 |
| Gillams RJ et al. | Comparative atomic-scale hydration of the ceramide and phosphocholine headgroup in solution and bilayer environments. | 2016 | J Chem Phys | pmid:27306021 |
| Barriga HM et al. | The effect of hydrostatic pressure on model membrane domain composition and lateral compressibility. | 2016 | Phys Chem Chem Phys | pmid:26601888 |
| Evans KO et al. | Feruloyl glycerol and 1,3-diferuloyl glycerol antioxidant behavior in phospholipid vesicles. | 2016 | Chem. Phys. Lipids | pmid:26561732 |
| Heberle FA et al. | Subnanometer Structure of an Asymmetric Model Membrane: Interleaflet Coupling Influences Domain Properties. | 2016 | Langmuir | pmid:27128636 |
| Jurak M | Effect of Lauryl Gallate on Wetting Properties of Organized Thin Phospholipid Films on Mica. | 2016 | J Phys Chem B | pmid:27332889 |
| Redondo-Morata L et al. | Effect of Statins on the Nanomechanical Properties of Supported Lipid Bilayers. | 2016 | Biophys. J. | pmid:27463138 |
| Hong CY et al. | Nonspecific Binding Domains in Lipid Membranes Induced by Phospholipase A2. | 2016 | Langmuir | pmid:27218880 |
| Fogarty JC et al. | Atomically detailed lipid bilayer models for the interpretation of small angle neutron and X-ray scattering data. | 2015 | Biochim. Biophys. Acta | pmid:25448879 |
| Kim MC et al. | Spatiotemporal dynamics of solvent-assisted lipid bilayer formation. | 2015 | Phys Chem Chem Phys | pmid:26539669 |
| Khadka NK et al. | Macroscopic and Nanoscopic Heterogeneous Structures in a Three-Component Lipid Bilayer Mixtures Determined by Atomic Force Microscopy. | 2015 | Langmuir | pmid:26506226 |
| Jeppesen JC et al. | Slow Relaxation of Shape and Orientational Texture in Membrane Gel Domains. | 2015 | Langmuir | pmid:26501924 |
| Dols-Perez A et al. | Nanoscale electric polarizability of ultrathin biolayers on insulating substrates by electrostatic force microscopy. | 2015 | Nanoscale | pmid:26488226 |
| Liu X and Chen KL | Interactions of Graphene Oxide with Model Cell Membranes: Probing Nanoparticle Attachment and Lipid Bilayer Disruption. | 2015 | Langmuir | pmid:26466194 |
| Suganami A et al. | Liposomally formulated phospholipid-conjugated indocyanine green for intra-operative brain tumor detection and resection. | 2015 | Int J Pharm | pmid:26453781 |
| Hirtz M et al. | Selective Binding of DNA Origami on Biomimetic Lipid Patches. | 2015 | Small | pmid:26389563 |
| Hirose M et al. | Liposome Membrane as a Platform for the L-Pro-Catalyzed Michael Addition of trans-β-Nitrostyrene and Acetone. | 2015 | Langmuir | pmid:26549731 |
| Moniruzzaman M et al. | Antimicrobial Peptide Lactoferricin B-Induced Rapid Leakage of Internal Contents from Single Giant Unilamellar Vesicles. | 2015 | Biochemistry | pmid:26368853 |
| Cui J et al. | Novel Raman-tagged sphingomyelin that closely mimics original raft-forming behavior. | 2015 | Bioorg. Med. Chem. | pmid:26026768 |
| Shimobayashi SF et al. | Direct measurement of DNA-mediated adhesion between lipid bilayers. | 2015 | Phys Chem Chem Phys | pmid:25989828 |
| Lin Q et al. | Decreasing Transmembrane Segment Length Greatly Decreases Perfringolysin O Pore Size. | 2015 | J. Membr. Biol. | pmid:25850715 |
| Schmidt TF et al. | Binding of methylene blue onto Langmuir monolayers representing cell membranes may explain its efficiency as photosensitizer in photodynamic therapy. | 2015 | Langmuir | pmid:25798992 |
| Basit H et al. | Aqueous-filled polymer microcavity arrays: versatile & stable lipid bilayer platforms offering high lateral mobility to incorporated membrane proteins. | 2015 | Analyst | pmid:25798456 |
| Pan J et al. | Structural and mechanical properties of cardiolipin lipid bilayers determined using neutron spin echo, small angle neutron and X-ray scattering, and molecular dynamics simulations. | 2015 | Soft Matter | pmid:25369786 |
| Du J et al. | Molecular simulation studies of human coagulation factor VIII C domain-mediated membrane binding. | 2015 | Thromb. Haemost. | pmid:25354705 |
| Yesylevskyy SO and Demchenko AP | Cholesterol behavior in asymmetric lipid bilayers: insights from molecular dynamics simulations. | 2015 | Methods Mol. Biol. | pmid:25331142 |
| Hu PC and Malmstadt N | Asymmetric giant lipid vesicle fabrication. | 2015 | Methods Mol. Biol. | pmid:25331129 |
| Arduin A et al. | Regulation of PLCβ2 by the electrostatic and mechanical properties of lipid bilayers. | 2015 | Sci Rep | pmid:26243281 |
| Cheng CY et al. | DMSO induces dehydration near lipid membrane surfaces. | 2015 | Biophys. J. | pmid:26200868 |
| Musgrove A and Bizzotto D | Potential Controls the Interaction of Liposomes with Octadecanol-Modified Au Electrodes: An in Situ AFM Study. | 2015 | Langmuir | pmid:26528884 |
| Lee H | Effects of imidazolium-based ionic surfactants on the size and dynamics of phosphatidylcholine bilayers with saturated and unsaturated chains. | 2015 | J. Mol. Graph. Model. | pmid:26055631 |
| Pierrat P and Lebeau L | Characterization of Titratable Amphiphiles in Lipid Membranes by Fluorescence Spectroscopy. | 2015 | Langmuir | pmid:26507074 |
| Markiewicz M et al. | Properties of water hydrating the galactolipid and phospholipid bilayers: a molecular dynamics simulation study. | 2015 | Acta Biochim. Pol. | pmid:26291044 |
| Unsay JD et al. | Atomic Force Microscopy Imaging and Force Spectroscopy of Supported Lipid Bilayers. | 2015 | J Vis Exp | pmid:26273958 |
| Chen Z et al. | Regulation of membrane-shape transitions induced by I-BAR domains. | 2015 | Biophys. J. | pmid:26200865 |
| Chavarha M et al. | Hydrophobic surfactant proteins strongly induce negative curvature. | 2015 | Biophys. J. | pmid:26153706 |
| Moser von Filseck J et al. | A phosphatidylinositol-4-phosphate powered exchange mechanism to create a lipid gradient between membranes. | 2015 | Nat Commun | pmid:25849868 |
| Rasmussen T et al. | Properties of the Mechanosensitive Channel MscS Pore Revealed by Tryptophan Scanning Mutagenesis. | 2015 | Biochemistry | pmid:26126964 |
| Adams PG et al. | Exploiting lipopolysaccharide-induced deformation of lipid bilayers to modify membrane composition and generate two-dimensional geometric membrane array patterns. | 2015 | Sci Rep | pmid:26015293 |
| Kardash ME et al. | Heterogeneities in Cholesterol-Containing Model Membranes Observed by Pulsed Electron Paramagnetic Resonance of Spin Labels. | 2015 | J Phys Chem B | pmid:25965099 |
| Yasuda T et al. | Deuterium NMR of raft model membranes reveals domain-specific order profiles and compositional distribution. | 2015 | Biophys. J. | pmid:25992728 |
| de Sá MM et al. | Understanding Miltefosine-Membrane Interactions Using Molecular Dynamics Simulations. | 2015 | Langmuir | pmid:25819781 |
| Kowal J et al. | Hybrid polymer-lipid films as platforms for directed membrane protein insertion. | 2015 | Langmuir | pmid:25849126 |
| Sakamoto S et al. | Effect of glycyrrhetinic acid on lipid raft model at the air/water interface. | 2015 | Biochim. Biophys. Acta | pmid:25445675 |
| Jobin ML et al. | The role of tryptophans on the cellular uptake and membrane interaction of arginine-rich cell penetrating peptides. | 2015 | Biochim. Biophys. Acta | pmid:25445669 |
| Dabkowska AP et al. | Assembly of RNA nanostructures on supported lipid bilayers. | 2015 | Nanoscale | pmid:25417592 |
| Tavano R et al. | The peculiar N- and (-termini of trichogin GA IV are needed for membrane interaction and human cell death induction at doses lacking antibiotic activity. | 2015 | Biochim. Biophys. Acta | pmid:25306964 |
| Liu Y and Mark Worden R | Size dependent disruption of tethered lipid bilayers by functionalized polystyrene nanoparticles. | 2015 | Biochim. Biophys. Acta | pmid:25285435 |
| Bavdek A et al. | Enzyme-coupled assays for flip-flop of acyl-Coenzyme A in liposomes. | 2015 | Biochim. Biophys. Acta | pmid:26325346 |
| Dick RA et al. | Hydrodynamic and Membrane Binding Properties of Purified Rous Sarcoma Virus Gag Protein. | 2015 | J. Virol. | pmid:26246573 |