1,2-Dioleoyl-sn-Glycero-3-Phosphocholine is a lipid of Glycerophospholipids (GP) class. 1,2-dioleoyl-sn-glycero-3-phosphocholine is associated with abnormalities such as Exanthema, Renal tubular disorder, Nodule, Gigantism and Mycoses. The involved functions are known as Lysis, Encapsulation, Process, Uptake and Flow or discharge. 1,2-dioleoyl-sn-glycero-3-phosphocholine often locates in Cytoplasmic matrix, Endosomes, soluble, Endoplasmic Reticulum and Membrane. The associated genes with 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine are P4HTM gene, synthetic peptide, BCAR1 gene, PCNA gene and CNTNAP1 gene. The related lipids are Liposomes, 1,2-oleoylphosphatidylcholine, 1,2-distearoylphosphatidylethanolamine, Butanols and Cardiolipins. The related experimental models are Mouse Model and Xenograft Model.
To understand associated biological information of 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
1,2-Dioleoyl-sn-Glycero-3-Phosphocholine is suspected in Gigantism, Nodule, protrusion, DERMATITIS HERPETIFORMIS, FAMILIAL, Exanthema, Renal tubular disorder and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Ovarian Neoplasms | D010051 | 10 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Neuroblastoma | D009447 | 66 associated lipids |
| Niemann-Pick Diseases | D009542 | 25 associated lipids |
| Celiac Disease | D002446 | 16 associated lipids |
| Atherosclerosis | D050197 | 85 associated lipids |
| Respiratory Syncytial Virus Infections | D018357 | 10 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
| Gene | Cross reference | Weighted score | Related literatures |
|---|
Xenograft Model are used in the study 'Therapeutic targeting of PELP1 prevents ovarian cancer growth and metastasis.' (Chakravarty D et al., 2011).
Mouse Model are used in the study 'Therapeutic EphA2 gene targeting in vivo using neutral liposomal small interfering RNA delivery.' (Landen CN et al., 2005).
| Model | Cross reference | Weighted score | Related literatures |
|---|
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Morandat S and El Kirat K | Real-time atomic force microscopy reveals cytochrome c-induced alterations in neutral lipid bilayers. | 2007 | Langmuir | pmid:17887784 |
| Andre G et al. | Probing the interaction forces between hydrophobic peptides and supported lipid bilayers using AFM. | 2007 Nov-Dec | J. Mol. Recognit. | pmid:17891753 |
| Huang SC et al. | Formation, stability, and mobility of one-dimensional lipid bilayers on polysilicon nanowires. | 2007 | Nano Lett. | pmid:17900161 |
| Chen L et al. | The partition of cholesterol between ordered and fluid bilayers of phosphatidylcholine: a synchrotron X-ray diffraction study. | 2007 | Biochim. Biophys. Acta | pmid:17900525 |
| Thormann E et al. | Ligand-receptor interactions and membrane structure investigated by AFM and time-resolved fluorescence microscopy. | 2007 Nov-Dec | J. Mol. Recognit. | pmid:17907279 |
| Datta P et al. | Membrane interactions of hemoglobin variants, HbA, HbE, HbF and globin subunits of HbA: effects of aminophospholipids and cholesterol. | 2008 | Biochim. Biophys. Acta | pmid:17916326 |
| Pabst G et al. | Entropy-driven softening of fluid lipid bilayers by alamethicin. | 2007 | Langmuir | pmid:17939689 |
| Lapinski MM et al. | Comparison of liposomes formed by sonication and extrusion: rotational and translational diffusion of an embedded chromophore. | 2007 | Langmuir | pmid:17939695 |
| Arnusch CJ et al. | Enhanced membrane pore formation by multimeric/oligomeric antimicrobial peptides. | 2007 | Biochemistry | pmid:17944489 |
| Buboltz JT et al. | High-resolution mapping of phase behavior in a ternary lipid mixture: do lipid-raft phase boundaries depend on the sample preparation procedure? | 2007 | Langmuir | pmid:17949025 |
| Park JW and Ahn DJ | Temperature effect on nanometer-scale physical properties of mixed phospholipid monolayers. | 2008 | Colloids Surf B Biointerfaces | pmid:17959364 |
| Moyano F et al. | On the investigation of the bilayer functionalities of 1,2-di-oleoyl-sn-glycero-3-phosphatidylcholine (DOPC) large unilamellar vesicles using cationic hemicyanines as optical probes: a wavelength-selective fluorescence approach. | 2008 | J Colloid Interface Sci | pmid:17961588 |
| Feng B et al. | In vitro P-glycoprotein assays to predict the in vivo interactions of P-glycoprotein with drugs in the central nervous system. | 2008 | Drug Metab. Dispos. | pmid:17962372 |
| Veatch SL et al. | Critical fluctuations in domain-forming lipid mixtures. | 2007 | Proc. Natl. Acad. Sci. U.S.A. | pmid:17962417 |
| Khakimov AM et al. | [State of water and its diffusion across lipid bilayers: effect of hydration degree]. | 2007 Sep-Oct | Biofizika | pmid:17969917 |
| Ira LJ and Johnston | Sphingomyelinase generation of ceramide promotes clustering of nanoscale domains in supported bilayer membranes. | 2008 | Biochim. Biophys. Acta | pmid:17988649 |
| Parisot J et al. | Molecular mechanism of target recognition by subtilin, a class I lanthionine antibiotic. | 2008 | Antimicrob. Agents Chemother. | pmid:17999970 |
| Kapralov AA et al. | The hierarchy of structural transitions induced in cytochrome c by anionic phospholipids determines its peroxidase activation and selective peroxidation during apoptosis in cells. | 2007 | Biochemistry | pmid:18004876 |
| Zimcik P et al. | Influence of aggregation on interaction of lipophilic, water-insoluble azaphthalocyanines with DOPC vesicles. | 2007 Nov-Dec | Photochem. Photobiol. | pmid:18028226 |
| Zakharov SD et al. | Helical alpha-synuclein forms highly conductive ion channels. | 2007 | Biochemistry | pmid:18031063 |
| Ringstad L et al. | An electrochemical study into the interaction between complement-derived peptides and DOPC mono- and bilayers. | 2008 | Langmuir | pmid:18052298 |
| Binder WH et al. | Guiding the location of nanoparticles into vesicular structures: a morphological study. | 2007 | Phys Chem Chem Phys | pmid:18060174 |
| Besenicar MP et al. | Kinetics of cholesterol extraction from lipid membranes by methyl-beta-cyclodextrin--a surface plasmon resonance approach. | 2008 | Biochim. Biophys. Acta | pmid:18068686 |
| Hesselink RW et al. | Membrane-bound peptides from V-ATPase subunit a do not interact with an indole-type inhibitor. | 2008 | J. Pept. Sci. | pmid:18069732 |
| Ramachandran R and Schmid SL | Real-time detection reveals that effectors couple dynamin's GTP-dependent conformational changes to the membrane. | 2008 | EMBO J. | pmid:18079695 |
| Stöckl M et al. | Alpha-synuclein selectively binds to anionic phospholipids embedded in liquid-disordered domains. | 2008 | J. Mol. Biol. | pmid:18082181 |
| Mathai JC et al. | Structural determinants of water permeability through the lipid membrane. | 2008 | J. Gen. Physiol. | pmid:18166626 |
| Jacobsen K and Risse T | On the origin of the polar order of T4 lysozyme on planar model surfaces. | 2008 | J Phys Chem B | pmid:18171040 |
| Shaw JE et al. | Cationic peptide-induced remodelling of model membranes: direct visualization by in situ atomic force microscopy. | 2008 | J. Struct. Biol. | pmid:18180166 |
| Rand Doyen J et al. | Phospholipid actions on PGHS-1 and -2 cyclooxygenase kinetics. | 2008 | Prostaglandins Other Lipid Mediat. | pmid:18201917 |
| Lei G and MacDonald RC | Effects on interactions of oppositely charged phospholipid vesicles of covalent attachment of polyethylene glycol oligomers to their surfaces: adhesion, hemifusion, full fusion and "endocytosis". | 2008 | J. Membr. Biol. | pmid:18202882 |
| Bacia K and Schwille P | Fluorescence correlation spectroscopy. | 2007 | Methods Mol. Biol. | pmid:18214375 |
| Orädd G and Lindblom G | Lateral diffusion coefficients of raft lipids from pulsed field gradient NMR. | 2007 | Methods Mol. Biol. | pmid:18214378 |
| Salamon Z et al. | Plasmon-waveguide resonance spectroscopy studies of lateral segregation in solid-supported proteolipid bilayers. | 2007 | Methods Mol. Biol. | pmid:18214380 |
| McIntosh TJ | X-ray diffraction to determine the thickness of raft and nonraft bilayers. | 2007 | Methods Mol. Biol. | pmid:18214383 |
| Pencer J et al. | Small-angle neutron scattering to detect rafts and lipid domains. | 2007 | Methods Mol. Biol. | pmid:18214384 |
| Burns AR | Atomic force microscopy of lipid domains in supported model membranes. | 2007 | Methods Mol. Biol. | pmid:18214386 |
| Li L and Cheng JX | Label-free coherent anti-stokes Raman scattering imaging of coexisting lipid domains in single bilayers. | 2008 | J Phys Chem B | pmid:18215035 |
| Mosser G et al. | Sub-domain structure of lipid-bound annexin-V resolved by electron image analysis. | 1991 | J. Mol. Biol. | pmid:1825119 |
| Karlovská J et al. | Effect of amphiphilic surfactant LDAO on the solubilization of DOPC vesicles and on the activity of Ca(2+)-ATPase reconstituted in DOPC vesicles. | 2007 | Gen. Physiol. Biophys. | pmid:18281747 |
| Domene C et al. | The role of conformation in ion permeation in a K+ channel. | 2008 | J. Am. Chem. Soc. | pmid:18293969 |
| Generosi J et al. | Infrared scanning near-field optical microscopy investigates order and clusters in model membranes. | 2008 | J Microsc | pmid:18304082 |
| Kóta Z et al. | Incorporation of transmembrane peptides from the vacuolar H(+)-ATPase in phospholipid membranes: spin-label electron paramagnetic resonance and polarized infrared spectroscopy. | 2008 | Biochemistry | pmid:18307317 |
| Hung WC et al. | Membrane-thinning effect of curcumin. | 2008 | Biophys. J. | pmid:18310254 |
| Masayama A et al. | Streptomyces phospholipase D mutants with altered substrate specificity capable of phosphatidylinositol synthesis. | 2008 | Chembiochem | pmid:18338352 |
| Terama E et al. | Influence of ethanol on lipid membranes: from lateral pressure profiles to dynamics and partitioning. | 2008 | J Phys Chem B | pmid:18341314 |
| Carmo VA et al. | Physicochemical characterization and study of in vitro interactions of pH-sensitive liposomes with the complement system. | 2008 | J Liposome Res | pmid:18348072 |
| Prata CA et al. | A new helper phospholipid for gene delivery. | 2008 | Chem. Commun. (Camb.) | pmid:18354801 |
| Cao Y et al. | Development of structure-lipid bilayer permeability relationships for peptide-like small organic molecules. | 2008 May-Jun | Mol. Pharm. | pmid:18355031 |
| Manojlovic V et al. | Membrane interactions of ternary phospholipid/cholesterol bilayers and encapsulation efficiencies of a RIP II protein. | 2008 | Colloids Surf B Biointerfaces | pmid:18359207 |
| Siu SW et al. | Biomolecular simulations of membranes: physical properties from different force fields. | 2008 | J Chem Phys | pmid:18376978 |
| Verma A et al. | Therapeutic significance of elevated tissue transglutaminase expression in pancreatic cancer. | 2008 | Clin. Cancer Res. | pmid:18413840 |
| Fox CB et al. | Monitoring the effects of component structure and source on formulation stability and adjuvant activity of oil-in-water emulsions. | 2008 | Colloids Surf B Biointerfaces | pmid:18440205 |
| Francius G et al. | Nanoscale membrane activity of surfactins: influence of geometry, charge and hydrophobicity. | 2008 | Biochim. Biophys. Acta | pmid:18455997 |
| Cans AS et al. | Positioning lipid membrane domains in giant vesicles by micro-organization of aqueous cytoplasm mimic. | 2008 | J. Am. Chem. Soc. | pmid:18479139 |
| Almela MJ et al. | Inhibitors of poliovirus uncoating efficiently block the early membrane permeabilization induced by virus particles. | 1991 | J. Virol. | pmid:1850030 |
| Kucerka N et al. | Lipid bilayer structure determined by the simultaneous analysis of neutron and X-ray scattering data. | 2008 | Biophys. J. | pmid:18502796 |
| Manley S et al. | Sorting of streptavidin protein coats on phase-separating model membranes. | 2008 | Biophys. J. | pmid:18502811 |
| Srividya N et al. | Determination of the line tension of giant vesicles from pore-closing dynamics. | 2008 | J Phys Chem B | pmid:18503265 |
| Ugolev Y et al. | Dissociation of Rac1(GDP).RhoGDI complexes by the cooperative action of anionic liposomes containing phosphatidylinositol 3,4,5-trisphosphate, Rac guanine nucleotide exchange factor, and GTP. | 2008 | J. Biol. Chem. | pmid:18505730 |
| Sun Y et al. | The bound states of amphipathic drugs in lipid bilayers: study of curcumin. | 2008 | Biophys. J. | pmid:18515370 |
| Pandit SA et al. | Cholesterol packing around lipids with saturated and unsaturated chains: a simulation study. | 2008 | Langmuir | pmid:18517226 |
| Lucero A et al. | Effect of hydrocarbon chain and pH on structural and topographical characteristics of phospholipid monolayers. | 2008 | J Phys Chem B | pmid:18517243 |
| Wang ST et al. | In situ x-ray reflectivity studies on the formation of substrate-supported phospholipid bilayers and monolayers. | 2008 | Phys Rev E Stat Nonlin Soft Matter Phys | pmid:18517424 |
| Yanagisawa M et al. | Shape deformation of ternary vesicles coupled with phase separation. | 2008 | Phys. Rev. Lett. | pmid:18518074 |
| Pan J et al. | Cholesterol perturbs lipid bilayers nonuniversally. | 2008 | Phys. Rev. Lett. | pmid:18518492 |
| Laflamme E et al. | Atomic force microscopy imaging of Bacillus thuringiensis Cry1 toxins interacting with insect midgut apical membranes. | 2008 | J. Membr. Biol. | pmid:18523711 |
| Chattopadhyay A and McNamee MG | Average membrane penetration depth of tryptophan residues of the nicotinic acetylcholine receptor by the parallax method. | 1991 | Biochemistry | pmid:1854727 |
| Yan W et al. | Reactive oxygen species play a central role in the activity of cationic liposome based cancer vaccine. | 2008 | J Control Release | pmid:18554742 |
| Efrat M et al. | Di-oleoyl phosphatidylcholine (PC-18:1) stimulates paraoxonase 1 (PON1) enzymatic and biological activities: in vitro and in vivo studies. | 2009 | Atherosclerosis | pmid:18585720 |
| Auguste DT et al. | Triggered release of siRNA from poly(ethylene glycol)-protected, pH-dependent liposomes. | 2008 | J Control Release | pmid:18601962 |
| Trunfio-Sfarghiu AM et al. | Role of nanomechanical properties in the tribological performance of phospholipid biomimetic surfaces. | 2008 | Langmuir | pmid:18620439 |
| Dabbas S et al. | Importance of the liposomal cationic lipid content and type in tumor vascular targeting: physicochemical characterization and in vitro studies using human primary and transformed endothelial cells. | 2008 Jul-Aug | Endothelium | pmid:18663622 |
| Kataoka-Hamai C et al. | Detection of supported lipid bilayers using their electric charge. | 2008 | Langmuir | pmid:18683957 |
| You L et al. | Anion transport properties of amine and amide-sidechained peptides are affected by charge and phospholipid composition. | 2008 | Org. Biomol. Chem. | pmid:18688484 |
| Fortunelli A and Monti S | Simulations of lipid adsorption on TiO2 surfaces in solution. | 2008 | Langmuir | pmid:18712891 |
| Das S et al. | Mechanical stability of micropipet-aspirated giant vesicles with fluid phase coexistence. | 2008 | J Phys Chem B | pmid:18717549 |
| Kantsler V et al. | Critical dynamics of vesicle stretching transition in elongational flow. | 2008 | Phys. Rev. Lett. | pmid:18764366 |
| Jeworrek C et al. | X-ray kinematography of phase transformations of three-component lipid mixtures: a time-resolved synchrotron X-ray scattering study using the pressure-jump relaxation technique. | 2008 | Langmuir | pmid:18767826 |
| Babu S et al. | Effect of size at the nanoscale and bilayer rigidity on skin diffusion of liposomes. | 2009 | J Biomed Mater Res A | pmid:18770522 |
| Haluska CK et al. | Combining fluorescence lifetime and polarization microscopy to discriminate phase separated domains in giant unilamellar vesicles. | 2008 | Biophys. J. | pmid:18790852 |
| Avila CL et al. | Role of electrostatics on membrane binding, aggregation and destabilization induced by NAD(P)H dehydrogenases. Implication in membrane fusion. | 2008 | Biophys. Chem. | pmid:18793820 |
| Siegel DP | The Gaussian curvature elastic energy of intermediates in membrane fusion. | 2008 | Biophys. J. | pmid:18805927 |
| Mircheva K et al. | Comparative study of lipolysis by PLA2 of DOPC substrates organized as monolayers, bilayer vesicles and nanocapsules. | 2008 | Colloids Surf B Biointerfaces | pmid:18818058 |
| van den Bogaart G et al. | On the mechanism of pore formation by melittin. | 2008 | J. Biol. Chem. | pmid:18819911 |
| Basu S et al. | Nitrite reductase activity of cytochrome c. | 2008 | J. Biol. Chem. | pmid:18820338 |
| Krishnaswamy R et al. | Aggregation of a peptide antibiotic alamethicin at the air-water interface and its influence on the viscoelasticity of phospholipid monolayers. | 2008 | Langmuir | pmid:18823083 |
| Zidovska A et al. | Block liposomes from curvature-stabilizing lipids: connected nanotubes, -rods, or -spheres. | 2009 | Langmuir | pmid:18834165 |
| Gillmor SD and Weiss PS | Dimpled vesicles: the interplay between energetics and transient pores. | 2008 | J Phys Chem B | pmid:18837538 |
| Popa R et al. | Entrance effects at nanopores of nanocapsules functionalized with poly(ethylene glycol) and their flow through nanochannels. | 2008 | Langmuir | pmid:18950201 |
| Santos O and Arnebrant T | Silica supported phospholipid layers doped with GM1: A comparison between different methods. | 2009 | J Colloid Interface Sci | pmid:18950789 |
| Grasso P et al. | A new role for follicle-stimulating hormone in the regulation of calcium flux in Sertoli cells: inhibition of Na+/Ca++ exchange. | 1991 | Endocrinology | pmid:1898879 |
| Tsumoto K et al. | Efficient formation of giant liposomes through the gentle hydration of phosphatidylcholine films doped with sugar. | 2009 | Colloids Surf B Biointerfaces | pmid:18993037 |
| Gissot A et al. | Sensitive liposomes encoded with oligonucleotide amphiphiles: a biocompatible switch. | 2008 | Chem. Commun. (Camb.) | pmid:18997948 |
| Christ K et al. | Membrane lipids determine the antibiotic activity of the lantibiotic gallidermin. | 2008 Nov-Dec | J. Membr. Biol. | pmid:19009315 |
| Ueno T et al. | Peroxynitrite affects lidocaine by acting on membrane-constituting lipids. | 2008 | J Anesth | pmid:19011794 |
| Kent B et al. | The inverse hexagonal - inverse ribbon - lamellar gel phase transition sequence in low hydration DOPC:DOPE phospholipid mixtures. | 2009 | Chem. Phys. Lipids | pmid:19026619 |
| Martinez-Seara H et al. | Influence of cis double-bond parametrization on lipid membrane properties: how seemingly insignificant details in force-field change even qualitative trends. | 2008 | J Chem Phys | pmid:19044940 |
| Róg T et al. | Comparison of cholesterol and its direct precursors along the biosynthetic pathway: effects of cholesterol, desmosterol and 7-dehydrocholesterol on saturated and unsaturated lipid bilayers. | 2008 | J Chem Phys | pmid:19045210 |
| RodrÃguez Niño MR et al. | Structural, topographical, and rheological characteristics of beta-casein-dioleoyl phosphatidylcholine (DOPC) mixed monolayers. | 2009 | Colloids Surf B Biointerfaces | pmid:19056249 |