1,2-Dioleoyl-sn-Glycero-3-Phosphocholine is a lipid of Glycerophospholipids (GP) class. 1,2-dioleoyl-sn-glycero-3-phosphocholine is associated with abnormalities such as Exanthema, Renal tubular disorder, Nodule, Gigantism and Mycoses. The involved functions are known as Lysis, Encapsulation, Process, Uptake and Flow or discharge. 1,2-dioleoyl-sn-glycero-3-phosphocholine often locates in Cytoplasmic matrix, Endosomes, soluble, Endoplasmic Reticulum and Membrane. The associated genes with 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine are P4HTM gene, synthetic peptide, BCAR1 gene, PCNA gene and CNTNAP1 gene. The related lipids are Liposomes, 1,2-oleoylphosphatidylcholine, 1,2-distearoylphosphatidylethanolamine, Butanols and Cardiolipins. The related experimental models are Mouse Model and Xenograft Model.
To understand associated biological information of 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
1,2-Dioleoyl-sn-Glycero-3-Phosphocholine is suspected in Gigantism, Nodule, protrusion, DERMATITIS HERPETIFORMIS, FAMILIAL, Exanthema, Renal tubular disorder and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Ovarian Neoplasms | D010051 | 10 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Neuroblastoma | D009447 | 66 associated lipids |
| Niemann-Pick Diseases | D009542 | 25 associated lipids |
| Celiac Disease | D002446 | 16 associated lipids |
| Atherosclerosis | D050197 | 85 associated lipids |
| Respiratory Syncytial Virus Infections | D018357 | 10 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
| Gene | Cross reference | Weighted score | Related literatures |
|---|
Xenograft Model are used in the study 'Therapeutic targeting of PELP1 prevents ovarian cancer growth and metastasis.' (Chakravarty D et al., 2011).
Mouse Model are used in the study 'Therapeutic EphA2 gene targeting in vivo using neutral liposomal small interfering RNA delivery.' (Landen CN et al., 2005).
| Model | Cross reference | Weighted score | Related literatures |
|---|
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Jaworsky M and Mendelsohn R | Fourier transform infrared spectroscopic identification of gel phase domains in reconstituted phospholipid vesicles containing Ca2+-ATPase. | 1986 | Biochim. Biophys. Acta | pmid:2943318 |
| Earnest JP et al. | Binding of local anesthetics to reconstituted acetylcholine receptors: effect of protein surface potential. | 1986 | Biochemistry | pmid:3022805 |
| Apell HJ and Marcus MM | (Na+ + K+)-ATPase in artificial lipid vesicles: influence of the concentration of mono- and divalent cations on the pumping rate. | 1986 | Biochim. Biophys. Acta | pmid:3022809 |
| Hantz E et al. | The osmotic response of large unilamellar vesicles studied by quasielastic light scattering. | 1986 | Biochim. Biophys. Acta | pmid:3778898 |
| Apell HJ et al. | Effects of the ATP, ADP and inorganic phosphate on the transport rate of the Na+,K+-pump. | 1986 | Biochim. Biophys. Acta | pmid:3008841 |
| Ho RJ et al. | Destabilization of target-sensitive immunoliposomes by antigen binding--a rapid assay for virus. | 1986 | Biochem. Biophys. Res. Commun. | pmid:3017345 |
| Stein O et al. | The role of apolipoprotein A-IV in reverse cholesterol transport studied with cultured cells and liposomes derived from an ether analog of phosphatidylcholine. | 1986 | Biochim. Biophys. Acta | pmid:3089295 |
| Isaacs BS et al. | A domain of membrane-bound blood coagulation factor Va is located far from the phospholipid surface. A fluorescence energy transfer measurement. | 1986 | Biochemistry | pmid:3768326 |
| Connor J et al. | Biodistribution of pH-sensitive immunoliposomes. | 1986 | Biochim. Biophys. Acta | pmid:3778935 |
| Ellens H et al. | Fusion of phosphatidylethanolamine-containing liposomes and mechanism of the L alpha-HII phase transition. | 1986 | Biochemistry | pmid:3741846 |