1,2-Dioleoyl-sn-Glycero-3-Phosphocholine is a lipid of Glycerophospholipids (GP) class. 1,2-dioleoyl-sn-glycero-3-phosphocholine is associated with abnormalities such as Exanthema, Renal tubular disorder, Nodule, Gigantism and Mycoses. The involved functions are known as Lysis, Encapsulation, Process, Uptake and Flow or discharge. 1,2-dioleoyl-sn-glycero-3-phosphocholine often locates in Cytoplasmic matrix, Endosomes, soluble, Endoplasmic Reticulum and Membrane. The associated genes with 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine are P4HTM gene, synthetic peptide, BCAR1 gene, PCNA gene and CNTNAP1 gene. The related lipids are Liposomes, 1,2-oleoylphosphatidylcholine, 1,2-distearoylphosphatidylethanolamine, Butanols and Cardiolipins. The related experimental models are Mouse Model and Xenograft Model.
To understand associated biological information of 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
1,2-Dioleoyl-sn-Glycero-3-Phosphocholine is suspected in Gigantism, Nodule, protrusion, DERMATITIS HERPETIFORMIS, FAMILIAL, Exanthema, Renal tubular disorder and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Ovarian Neoplasms | D010051 | 10 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Neuroblastoma | D009447 | 66 associated lipids |
| Niemann-Pick Diseases | D009542 | 25 associated lipids |
| Celiac Disease | D002446 | 16 associated lipids |
| Atherosclerosis | D050197 | 85 associated lipids |
| Respiratory Syncytial Virus Infections | D018357 | 10 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
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| Lipid concept | Cross reference | Weighted score | Related literatures |
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| Gene | Cross reference | Weighted score | Related literatures |
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Xenograft Model are used in the study 'Therapeutic targeting of PELP1 prevents ovarian cancer growth and metastasis.' (Chakravarty D et al., 2011).
Mouse Model are used in the study 'Therapeutic EphA2 gene targeting in vivo using neutral liposomal small interfering RNA delivery.' (Landen CN et al., 2005).
| Model | Cross reference | Weighted score | Related literatures |
|---|
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Le Saux A et al. | Membrane molecule reorientation in an electric field recorded by attenuated total reflection Fourier-transform infrared spectroscopy. | 2001 | Biophys. J. | pmid:11159405 |
| Hristova K et al. | Structure, location, and lipid perturbations of melittin at the membrane interface. | 2001 | Biophys. J. | pmid:11159447 |
| Guy B et al. | Design, characterization and preclinical efficacy of a cationic lipid adjuvant for influenza split vaccine. | 2001 | Vaccine | pmid:11166905 |
| Strandberg E et al. | Phase diagrams of systems with cationic alpha-helical membrane-spanning model peptides and dioleoylphosphatidylcholine. | 2001 | Adv Colloid Interface Sci | pmid:11215795 |
| Dietrich C et al. | Lipid rafts reconstituted in model membranes. | 2001 | Biophys. J. | pmid:11222302 |
| Snitsarev V et al. | Fluorescent detection of Zn(2+)-rich vesicles with Zinquin: mechanism of action in lipid environments. | 2001 | Biophys. J. | pmid:11222314 |
| Salamon Z and Tollin G | Optical anisotropy in lipid bilayer membranes: coupled plasmon-waveguide resonance measurements of molecular orientation, polarizability, and shape. | 2001 | Biophys. J. | pmid:11222316 |
| Mondal M et al. | Effect of cholesterol on interaction of dibucaine with phospholipid vesicles: a fluorescence study. | 2001 | Biochim. Biophys. Acta | pmid:11248213 |
| Tsuchiya H | Stereospecificity in membrane effects of catechins. | 2001 | Chem. Biol. Interact. | pmid:11248221 |
| Kisel MA et al. | Influence of ethanol and phosphatidylethanol on the activity of pancreatic phospholipase A2. | 2001 | Biochemistry Mosc. | pmid:11255124 |