1,2-Dioleoyl-sn-Glycero-3-Phosphocholine is a lipid of Glycerophospholipids (GP) class. 1,2-dioleoyl-sn-glycero-3-phosphocholine is associated with abnormalities such as Exanthema, Renal tubular disorder, Nodule, Gigantism and Mycoses. The involved functions are known as Lysis, Encapsulation, Process, Uptake and Flow or discharge. 1,2-dioleoyl-sn-glycero-3-phosphocholine often locates in Cytoplasmic matrix, Endosomes, soluble, Endoplasmic Reticulum and Membrane. The associated genes with 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine are P4HTM gene, synthetic peptide, BCAR1 gene, PCNA gene and CNTNAP1 gene. The related lipids are Liposomes, 1,2-oleoylphosphatidylcholine, 1,2-distearoylphosphatidylethanolamine, Butanols and Cardiolipins. The related experimental models are Mouse Model and Xenograft Model.
To understand associated biological information of 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
1,2-Dioleoyl-sn-Glycero-3-Phosphocholine is suspected in Gigantism, Nodule, protrusion, DERMATITIS HERPETIFORMIS, FAMILIAL, Exanthema, Renal tubular disorder and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Ovarian Neoplasms | D010051 | 10 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Neuroblastoma | D009447 | 66 associated lipids |
| Niemann-Pick Diseases | D009542 | 25 associated lipids |
| Celiac Disease | D002446 | 16 associated lipids |
| Atherosclerosis | D050197 | 85 associated lipids |
| Respiratory Syncytial Virus Infections | D018357 | 10 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
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| Function | Cross reference | Weighted score | Related literatures |
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| Lipid concept | Cross reference | Weighted score | Related literatures |
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| Gene | Cross reference | Weighted score | Related literatures |
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Xenograft Model are used in the study 'Therapeutic targeting of PELP1 prevents ovarian cancer growth and metastasis.' (Chakravarty D et al., 2011).
Mouse Model are used in the study 'Therapeutic EphA2 gene targeting in vivo using neutral liposomal small interfering RNA delivery.' (Landen CN et al., 2005).
| Model | Cross reference | Weighted score | Related literatures |
|---|
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Yoon YZ et al. | Mechanical properties of ternary lipid membranes near a liquid-liquid phase separation boundary. | 2010 | J Phys Condens Matter | pmid:21389358 |
| Orsi M et al. | Coarse-grain modelling of DMPC and DOPC lipid bilayers. | 2010 | J Phys Condens Matter | pmid:21389551 |
| Mihailescu M et al. | Acyl-chain methyl distributions of liquid-ordered and -disordered membranes. | 2011 | Biophys. J. | pmid:21402027 |
| Perlo J et al. | Temperature and size-dependence of membrane molecular dynamics in unilamellar vesicles by fast field-cycling NMR relaxometry. | 2011 | J Phys Chem B | pmid:21405038 |
| Zhou H et al. | Stretching and relaxation of vesicles. | 2011 | Phys Rev E Stat Nonlin Soft Matter Phys | pmid:21405711 |
| Chakravarty D et al. | Therapeutic targeting of PELP1 prevents ovarian cancer growth and metastasis. | 2011 | Clin. Cancer Res. | pmid:21421858 |
| Kausik R and Han S | Dynamics and state of lipid bilayer-internal water unraveled with solution state 1H dynamic nuclear polarization. | 2011 | Phys Chem Chem Phys | pmid:21423982 |
| Lee OS and Schatz GC | Computational simulations of the interaction of lipid membranes with DNA-functionalized gold nanoparticles. | 2011 | Methods Mol. Biol. | pmid:21424456 |
| Opilik L et al. | Nanoscale chemical imaging of segregated lipid domains using tip-enhanced Raman spectroscopy. | 2011 | Phys Chem Chem Phys | pmid:21431176 |
| Murail S et al. | Microsecond simulations indicate that ethanol binds between subunits and could stabilize an open-state model of a glycine receptor. | 2011 | Biophys. J. | pmid:21463577 |
| Venkatesan BM et al. | Lipid bilayer coated Al(2)O(3) nanopore sensors: towards a hybrid biological solid-state nanopore. | 2011 | Biomed Microdevices | pmid:21487665 |
| Tejwani RW et al. | Functional group dependence of solute partitioning to various locations within a DOPC bilayer: a comparison of molecular dynamics simulations with experiment. | 2011 | J Pharm Sci | pmid:21491439 |
| Tamba Y et al. | A membrane filtering method for the purification of giant unilamellar vesicles. | 2011 | Chem. Phys. Lipids | pmid:21524642 |
| Bao R et al. | Atomic force microscopy study of ganglioside GM1 concentration effect on lateral phase separation of sphingomyelin/dioleoylphosphatidylcholine/cholesterol bilayers. | 2011 | J Phys Chem B | pmid:21526782 |
| Korstanje LJ et al. | Effects of steroid molecules on the dynamical structure of dioleoylphosphatidylcholine and digalactosyldiacylglycerol bilayers. | 1990 | Biochim. Biophys. Acta | pmid:2155018 |
| Klacsová M et al. | The effect of aliphatic alcohols on fluid bilayers in unilamellar DOPC vesicles--a small-angle neutron scattering and molecular dynamics study. | 2011 | Biochim. Biophys. Acta | pmid:21554856 |
| Mignet N et al. | Development of a liposomal formulation of the natural flavonoid fisetin. | 2012 | Int J Pharm | pmid:21571054 |
| Verardi R et al. | Structural topology of phospholamban pentamer in lipid bilayers by a hybrid solution and solid-state NMR method. | 2011 | Proc. Natl. Acad. Sci. U.S.A. | pmid:21576492 |
| Sleight RG and Dao HN | Synergistic activation of CTP:phosphocholine cytidylyltransferase by phosphatidylethanolamine and oleic acid. | 1990 | Lipids | pmid:2158609 |
| Å achl R et al. | Distribution of BODIPY-labelled phosphatidylethanolamines in lipid bilayers exhibiting different curvatures. | 2011 | Phys Chem Chem Phys | pmid:21597615 |
| González-Rubio P et al. | Amphipathic-Lipid-Packing-Sensor interactions with lipids assessed by atomistic molecular dynamics. | 2011 | Biochim. Biophys. Acta | pmid:21600869 |
| Hianik T et al. | Specific volume and compressibility of bilayer lipid membranes with incorporated Na,K-ATPase. | 2011 | Gen. Physiol. Biophys. | pmid:21613669 |
| Janas T et al. | The effect of long-chain bases on polysialic acid-mediated membrane interactions. | 2011 | Biochim. Biophys. Acta | pmid:21616054 |
| Nyholm TK et al. | Construction of a DOPC/PSM/cholesterol phase diagram based on the fluorescence properties of trans-parinaric acid. | 2011 | Langmuir | pmid:21627141 |
| Hildebrandt P et al. | Quantitative conformational analysis of cytochrome c bound to phospholipid vesicles studied by resonance Raman spectroscopy. | 1990 | Eur. Biophys. J. | pmid:2162758 |
| Hane F et al. | Amyloid-β aggregation on model lipid membranes: an atomic force microscopy study. | 2011 | J. Alzheimers Dis. | pmid:21694459 |
| Nguyen TT and Conboy JC | High-throughput screening of drug-lipid membrane interactions via counter-propagating second harmonic generation imaging. | 2011 | Anal. Chem. | pmid:21696170 |
| Berkovich AK et al. | Dipole potential as a driving force for the membrane insertion of polyacrylic acid in slightly acidic milieu. | 2012 | Biochim. Biophys. Acta | pmid:21703225 |
| Warshaviak DT et al. | Effect of membrane tension on the electric field and dipole potential of lipid bilayer membrane. | 2011 | Biochim. Biophys. Acta | pmid:21722624 |
| MacCallum JL et al. | Transfer of arginine into lipid bilayers is nonadditive. | 2011 | Biophys. J. | pmid:21723820 |
| Becucci L et al. | Gel-phase microdomains and lipid rafts in monolayers affect the redox properties of ubiquinone-10. | 2011 | Biophys. J. | pmid:21723823 |
| Berka K et al. | Membrane position of ibuprofen agrees with suggested access path entrance to cytochrome P450 2C9 active site. | 2011 | J Phys Chem A | pmid:21744854 |
| Jagoda A et al. | Interactions of biodegradable poly([R]-3-hydroxy-10-undecenoate) with 1,2-dioleoyl-sn-glycero-3-phosphocholine lipid: a monolayer study. | 2011 | Langmuir | pmid:21749038 |
| Norris FA and Powell GL | The apparent permeability coefficient for proton flux through phosphatidylcholine vesicles is dependent on the direction of flux. | 1990 | Biochim. Biophys. Acta | pmid:2176102 |
| Konyakhina TM et al. | Control of a nanoscopic-to-macroscopic transition: modulated phases in four-component DSPC/DOPC/POPC/Chol giant unilamellar vesicles. | 2011 | Biophys. J. | pmid:21767476 |
| Greisen P et al. | Linear rate-equilibrium relations arising from ion channel-bilayer energetic coupling. | 2011 | Proc. Natl. Acad. Sci. U.S.A. | pmid:21768343 |
| Chen B et al. | Role of reverse micelles on lipid oxidation in bulk oils: impact of phospholipids on antioxidant activity of α-tocopherol and Trolox. | 2011 | Food Funct | pmid:21779568 |
| Pisani M et al. | Biophysical characterization of complexes of DNA with mixtures of the neutral lipids 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-hexanoylamine or 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-dodecanoylamine and 1,2-dioleoyl-sn-glycero-3-phosphocholine in the presence of bivalent metal cations for DNA transfection. | 2011 | J Phys Chem B | pmid:21790167 |
| Ghosh SK et al. | Effect of PIP2 on bilayer structure and phase behavior of DOPC: an X-ray scattering study. | 2011 | Chemphyschem | pmid:21826776 |
| Tsaloglou MN et al. | The effect of lipids on the enzymatic activity of 6-phosphofructo-1-kinase from B. stearothermophilus. | 2011 | Chem. Phys. Lipids | pmid:21871874 |
| Paiva AD et al. | Role of lipid II and membrane thickness in the mechanism of action of the lantibiotic bovicin HC5. | 2011 | Antimicrob. Agents Chemother. | pmid:21876041 |
| Abe M et al. | Molecular mechanisms for the induction of peroxidase activity of the cytochrome c-cardiolipin complex. | 2011 | Biochemistry | pmid:21877718 |
| Brown AT et al. | Active rheology of phospholipid vesicles. | 2011 | Phys Rev E Stat Nonlin Soft Matter Phys | pmid:21929041 |
| Dols-Perez A et al. | Ultrathin spin-coated dioleoylphosphatidylcholine lipid layers in dry conditions: a combined atomic force microscopy and nanomechanical study. | 2011 | Langmuir | pmid:21936555 |
| Juhasz J et al. | Fluorescent probe partitioning in GUVs of binary phospholipid mixtures: implications for interpreting phase behavior. | 2012 | Biochim. Biophys. Acta | pmid:21945563 |
| Nick AM et al. | Silencing of p130cas in ovarian carcinoma: a novel mechanism for tumor cell death. | 2011 | J. Natl. Cancer Inst. | pmid:21957230 |
| WiÄ…cek AE | Influence of dipalmitoylphosphatidylcholine (or dioleoylphosphatidylcholine) and phospholipase A2 enzyme on the properties of emulsions. | 2012 | J Colloid Interface Sci | pmid:21993551 |
| Pullmannová P et al. | The ionic strength effect on the DNA complexation by DOPC - gemini surfactants liposomes. | 2012 | Biophys. Chem. | pmid:21996510 |
| Falkman P et al. | Lyotropic lipid phases confined in cylindrical pores: structure and permeability. | 2011 | J Phys Chem B | pmid:22007791 |
| Kneller GR et al. | Communication: consistent picture of lateral subdiffusion in lipid bilayers: molecular dynamics simulation and exact results. | 2011 | J Chem Phys | pmid:22010688 |
| Stabley DR et al. | Visualizing mechanical tension across membrane receptors with a fluorescent sensor. | 2012 | Nat. Methods | pmid:22037704 |
| Li J et al. | Calcium phosphate nanoparticles with an asymmetric lipid bilayer coating for siRNA delivery to the tumor. | 2012 | J Control Release | pmid:22056915 |
| Michelangeli F et al. | The conformation of pyrethroids bound to lipid bilayers. | 1990 | Biochim. Biophys. Acta | pmid:2207119 |
| Bae SJ et al. | Budding dynamics of the lipid membrane. | 2011 | J Nanosci Nanotechnol | pmid:22121680 |
| Nguyen TT et al. | Comparison of the energetics of avidin, streptavidin, neutrAvidin, and anti-biotin antibody binding to biotinylated lipid bilayer examined by second-harmonic generation. | 2012 | Anal. Chem. | pmid:22122646 |
| Nordin D et al. | Protein directed assembly of lipids. | 2012 | Chem. Commun. (Camb.) | pmid:22129789 |
| Orth A et al. | Creating and modulating microdomains in pore-spanning membranes. | 2012 | Chemphyschem | pmid:22135099 |
| Lim JB et al. | Update of the cholesterol force field parameters in CHARMM. | 2012 | J Phys Chem B | pmid:22136112 |
| Kirchner SR et al. | Membrane composition of jetted lipid vesicles: a Raman spectroscopy study. | 2012 | J Biophotonics | pmid:22147675 |
| Wang T et al. | Nanomechanical recognition of sphingomyelin-rich membrane domains by atomic force microscopy. | 2012 | Biochemistry | pmid:22148674 |
| Yu J et al. | The boundary lubrication of chemically grafted and cross-linked hyaluronic acid in phosphate buffered saline and lipid solutions measured by the surface forces apparatus. | 2012 | Langmuir | pmid:22148857 |
| Yang SC and Faller R | Pressure and surface tension control self-assembled structures in mixtures of Pegylated and non-pegylated lipids. | 2012 | Langmuir | pmid:22148936 |
| Li GC et al. | Solid-state NMR analysis of steroidal conformation of 17α- and 17β-estradiol in the absence and presence of lipid environment. | 2012 | Steroids | pmid:22155023 |
| Sheikh K et al. | Differing modes of interaction between monomeric Aβ(1-40) peptides and model lipid membranes: an AFM study. | 2012 | Chem. Phys. Lipids | pmid:22182491 |
| Orsi M and Essex JW | The ELBA force field for coarse-grain modeling of lipid membranes. | 2011 | PLoS ONE | pmid:22194874 |
| Cardarelli F et al. | Cholesterol-dependent macropinocytosis and endosomal escape control the transfection efficiency of lipoplexes in CHO living cells. | 2012 | Mol. Pharm. | pmid:22196199 |
| An HH et al. | Effect of plasma etching on photoluminescence of SnO(x)/Sn nanoparticles deposited on DOPC lipid membrane. | 2012 | J Colloid Interface Sci | pmid:22196347 |
| Woller JG et al. | Reversible hybridization of DNA anchored to a lipid membrane via porphyrin. | 2012 | Langmuir | pmid:22201337 |
| Tsao FH et al. | The use of a multichannel scaling method to detect radioactive species in spread monolayers. | 1990 | Anal. Biochem. | pmid:2221346 |
| Ormategui N et al. | Interaction of poly(N-isopropylacrylamide) (pNIPAM) based nanoparticles and their linear polymer precursor with phospholipid membrane models. | 2012 | Bioelectrochemistry | pmid:22249139 |
| Afkhami F et al. | Encapsulation of magnetotactic bacteria for targeted and controlled delivery of anticancer agents for tumor therapy. | 2011 | Conf Proc IEEE Eng Med Biol Soc | pmid:22255868 |
| RodrÃguez G et al. | A unique bicellar nanosystem combining two effects on stratum corneum lipids. | 2012 | Mol. Pharm. | pmid:22264106 |
| Sekula-Neuner S et al. | Allergen arrays for antibody screening and immune cell activation profiling generated by parallel lipid dip-pen nanolithography. | 2012 | Small | pmid:22278752 |
| Zimmermann R et al. | Fluidity modulation of phospholipid bilayers by electrolyte ions: insights from fluorescence microscopy and microslit electrokinetic experiments. | 2012 | J Phys Chem A | pmid:22304400 |
| Raghunathan M et al. | Structure and elasticity of lipid membranes with genistein and daidzein bioflavinoids using X-ray scattering and MD simulations. | 2012 | J Phys Chem B | pmid:22324769 |
| Muddana HS et al. | Tuning membrane phase separation using nonlipid amphiphiles. | 2012 | Biophys. J. | pmid:22325271 |
| Vanegas JM et al. | Role of unsaturated lipid and ergosterol in ethanol tolerance of model yeast biomembranes. | 2012 | Biophys. J. | pmid:22325273 |
| Pierrat P et al. | A cationic phospholipid-detergent conjugate as a new efficient carrier for siRNA delivery. | 2012 | Chemistry | pmid:22362588 |
| Li X et al. | Preparation of supported lipid membranes for aquaporin Z incorporation. | 2012 | Colloids Surf B Biointerfaces | pmid:22386862 |
| Dods RH et al. | The innate reactivity of a membrane associated peptide towards lipids: acyl transfer to melittin without enzyme catalysis. | 2012 | Org. Biomol. Chem. | pmid:22407502 |
| Domenici F et al. | Temperature-dependent structural changes on DDAB surfactant assemblies evidenced by energy dispersive X-ray diffraction and dynamic light scattering. | 2012 | Colloids Surf B Biointerfaces | pmid:22429784 |
| Fonseca-Maldonado R et al. | The bactericidal effect of human secreted group IID phospholipase A2 results from both hydrolytic and non-hydrolytic activities. | 2012 | Biochimie | pmid:22490726 |
| Shoji Y et al. | Liposome solubilization induced by surfactant molecules in a microchip. | 2012 | Anal Sci | pmid:22498459 |
| Igarashi T et al. | Anomalous solubilization behavior of dimyristoylphosphatidylcholine liposomes induced by sodium dodecyl sulfate micelles. | 2012 | Anal Sci | pmid:22498460 |
| Chamorro C et al. | Enhancing membrane disruption by targeting and multivalent presentation of antimicrobial peptides. | 2012 | Biochim. Biophys. Acta | pmid:22525599 |
| Costard R et al. | Ultrafast vibrational dynamics of water confined in phospholipid reverse micelles. | 2012 | J Phys Chem B | pmid:22546057 |
| Kurniawan Y et al. | n-Butanol partitioning and phase behavior in DPPC/DOPC membranes. | 2012 | J Phys Chem B | pmid:22546177 |
| Stock RP et al. | Sphingomyelinase D activity in model membranes: structural effects of in situ generation of ceramide-1-phosphate. | 2012 | PLoS ONE | pmid:22558302 |
| Mauroy C et al. | Giant lipid vesicles under electric field pulses assessed by non invasive imaging. | 2012 | Bioelectrochemistry | pmid:22560131 |
| Iwabuchi S et al. | Transport of actin-decorated liposomes along myosin molecules in vitro. | 2012 | Biochem. Biophys. Res. Commun. | pmid:22575445 |
| Reddy AS et al. | Effect of membrane tension on the physical properties of DOPC lipid bilayer membrane. | 2012 | Biochim. Biophys. Acta | pmid:22588133 |
| Wallace SJ et al. | Interaction of colistin and colistin methanesulfonate with liposomes: colloidal aspects and implications for formulation. | 2012 | J Pharm Sci | pmid:22623044 |
| Baruah B and Surin A | Interaction of liposome-encapsulated cisplatin with biomolecules. | 2012 | J. Biol. Inorg. Chem. | pmid:22674433 |
| Zhang S et al. | Freezing or wrapping: the role of particle size in the mechanism of nanoparticle-biomembrane interaction. | 2012 | Langmuir | pmid:22717012 |
| Mechaly AE et al. | Pores of the toxin FraC assemble into 2D hexagonal clusters in both crystal structures and model membranes. | 2012 | J. Struct. Biol. | pmid:22728830 |
| Konopka K et al. | Liposomes modulate human immunodeficiency virus infectivity. | 1990 | J. Gen. Virol. | pmid:2273389 |
| Matson M et al. | Spectral properties and orientation of voltage-sensitive dyes in lipid membranes. | 2012 | Langmuir | pmid:22738247 |
| Betaneli V et al. | Effect of temperature on the formation of liquid phase-separating giant unilamellar vesicles (GUV). | 2012 | Chem. Phys. Lipids | pmid:22750641 |
| Rostovtseva TK et al. | Membrane lipid composition regulates tubulin interaction with mitochondrial voltage-dependent anion channel. | 2012 | J. Biol. Chem. | pmid:22763701 |
| Baoukina S et al. | Molecular structure of membrane tethers. | 2012 | Biophys. J. | pmid:22768942 |