1,2-Dioleoyl-sn-Glycero-3-Phosphocholine is a lipid of Glycerophospholipids (GP) class. 1,2-dioleoyl-sn-glycero-3-phosphocholine is associated with abnormalities such as Exanthema, Renal tubular disorder, Nodule, Gigantism and Mycoses. The involved functions are known as Lysis, Encapsulation, Process, Uptake and Flow or discharge. 1,2-dioleoyl-sn-glycero-3-phosphocholine often locates in Cytoplasmic matrix, Endosomes, soluble, Endoplasmic Reticulum and Membrane. The associated genes with 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine are P4HTM gene, synthetic peptide, BCAR1 gene, PCNA gene and CNTNAP1 gene. The related lipids are Liposomes, 1,2-oleoylphosphatidylcholine, 1,2-distearoylphosphatidylethanolamine, Butanols and Cardiolipins. The related experimental models are Mouse Model and Xenograft Model.
To understand associated biological information of 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
1,2-Dioleoyl-sn-Glycero-3-Phosphocholine is suspected in Gigantism, Nodule, protrusion, DERMATITIS HERPETIFORMIS, FAMILIAL, Exanthema, Renal tubular disorder and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Ovarian Neoplasms | D010051 | 10 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Neuroblastoma | D009447 | 66 associated lipids |
| Niemann-Pick Diseases | D009542 | 25 associated lipids |
| Celiac Disease | D002446 | 16 associated lipids |
| Atherosclerosis | D050197 | 85 associated lipids |
| Respiratory Syncytial Virus Infections | D018357 | 10 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
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| Function | Cross reference | Weighted score | Related literatures |
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| Lipid concept | Cross reference | Weighted score | Related literatures |
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| Gene | Cross reference | Weighted score | Related literatures |
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Xenograft Model are used in the study 'Therapeutic targeting of PELP1 prevents ovarian cancer growth and metastasis.' (Chakravarty D et al., 2011).
Mouse Model are used in the study 'Therapeutic EphA2 gene targeting in vivo using neutral liposomal small interfering RNA delivery.' (Landen CN et al., 2005).
| Model | Cross reference | Weighted score | Related literatures |
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| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| pmid: | ||||
| Garcia-Fandiño R et al. | Lipid Bilayer Membrane Perturbation by Embedded Nanopores: A Simulation Study. | 2016 | ACS Nano | pmid:26943498 |
| Winkler PM et al. | Transient Nanoscopic Phase Separation in Biological Lipid Membranes Resolved by Planar Plasmonic Antennas. | 2017 | ACS Nano | pmid:28696660 |
| Mihut AM et al. | Tunable adsorption of soft colloids on model biomembranes. | 2013 | ACS Nano | pmid:24191704 |
| Yilmaz N and Kobayashi T | Visualization of Lipid Membrane Reorganization Induced by a Pore-Forming Toxin Using High-Speed Atomic Force Microscopy. | 2015 | ACS Nano | pmid:26222645 |
| Gordillo GJ et al. | Interactions of gold nanoparticles with a phospholipid monolayer membrane on mercury. | 2014 | ACS Nano | pmid:24878256 |
| Vakurov A et al. | Direct characterization of fluid lipid assemblies on mercury in electric fields. | 2014 | ACS Nano | pmid:24625246 |
| Perrault SD and Shih WM | Virus-inspired membrane encapsulation of DNA nanostructures to achieve in vivo stability. | 2014 | ACS Nano | pmid:24694301 |
| Andrecka J et al. | Direct observation and control of supported lipid bilayer formation with interferometric scattering microscopy. | 2013 | ACS Nano | pmid:24251388 |
| Krylov NA et al. | Nontrivial behavior of water in the vicinity and inside lipid bilayers as probed by molecular dynamics simulations. | 2013 | ACS Nano | pmid:24070369 |
| Tashiro K et al. | Modified natural and synthetically reconstituted surfactant therapies for acute lung injury caused by endotoxin in rats. | 1999 | Acta Anaesthesiol Scand | pmid:10492410 |
| Rudolphi-Skórska E et al. | Impact of polyphenol-rich green tea extracts on the protection of DOPC monolayer against damage caused by ozone induced lipid oxidation. | 2018 | Acta Biochim. Pol. | pmid:29850658 |
| Janas T et al. | The effect of undecaprenol on bilayer lipid membranes. | 1994 | Acta Biochim. Pol. | pmid:7856407 |
| Janas T et al. | The effect of hexadecaprenol on molecular organisation and transport properties of model membranes. | 2000 | Acta Biochim. Pol. | pmid:11310968 |
| Markiewicz M et al. | Properties of water hydrating the galactolipid and phospholipid bilayers: a molecular dynamics simulation study. | 2015 | Acta Biochim. Pol. | pmid:26291044 |
| Woźniak M et al. | Diversity of the effect of phosphatidylcholine and sphingomyelin on adenylate deaminase from pig brain. | 1987 | Acta Biochim. Pol. | pmid:3687300 |
| Darkes MJ and Bradshaw JP | Real-time swelling-series method improves the accuracy of lamellar neutron-diffraction data. | 2000 | Acta Crystallogr. D Biol. Crystallogr. | pmid:10666626 |
| Kutas J and Bodor A | [Introduction of liposomes: examination methods and their importance in research and quality assurance]. | 2001 | Acta Pharm Hung | pmid:12113182 |
| Moleiro LH et al. | Permeability modes in fluctuating lipid membranes with DNA-translocating pores. | 2017 | Adv Colloid Interface Sci | pmid:28735883 |
| Strandberg E et al. | Phase diagrams of systems with cationic alpha-helical membrane-spanning model peptides and dioleoylphosphatidylcholine. | 2001 | Adv Colloid Interface Sci | pmid:11215795 |
| Wang F et al. | Orthogonal adsorption onto nano-graphene oxide using different intermolecular forces for multiplexed delivery. | 2013 | Adv. Mater. Weinheim | pmid:23722422 |
| Yoon J et al. | Nanoparticles of conjugated polymers prepared from phase-separated films of phospholipids and polymers for biomedical applications. | 2014 | Adv. Mater. Weinheim | pmid:24789764 |
| Subramaniam AB et al. | Particle/Fluid interface replication as a means of producing topographically patterned polydimethylsiloxane surfaces for deposition of lipid bilayers. | 2010 | Adv. Mater. Weinheim | pmid:20376852 |
| Aoyagi S et al. | ToF-SIMS observation for evaluating the interaction between amyloid β and lipid membranes. | 2015 | Anal Bioanal Chem | pmid:25687682 |
| Lindholm-Sethson B et al. | Gramicidin A interaction at a dioleoyl phosphatidylcholine monolayer on a mercury drop electrode. | 2003 | Anal Bioanal Chem | pmid:12589498 |
| Shoji Y et al. | Liposome solubilization induced by surfactant molecules in a microchip. | 2012 | Anal Sci | pmid:22498459 |
| Watanabe H and Kawano R | Channel Current Analysis for Pore-forming Properties of an Antimicrobial Peptide, Magainin 1, Using the Droplet Contact Method. | 2016 | Anal Sci | pmid:26753706 |
| Ohno M et al. | Changes in Interfacial Tension of a Lipid Membrane Formed at the Water/Chloroform Interface upon DNA Complex Formation. | 2015 | Anal Sci | pmid:26460361 |
| Tsuchiya H et al. | Antioxidant activity analysis by liposomal membrane system and application to anesthetics. | 2008 | Anal Sci | pmid:19075464 |
| Igarashi T et al. | Anomalous solubilization behavior of dimyristoylphosphatidylcholine liposomes induced by sodium dodecyl sulfate micelles. | 2012 | Anal Sci | pmid:22498460 |
| Nomoto T et al. | Effects of Cholesterol Concentration and Osmolarity on the Fluidity and Membrane Tension of Free-standing Black Lipid Membranes. | 2018 | Anal Sci | pmid:29962374 |
| Mezna M and Lawrence AJ | Conductimetric assays for the hydrolase and transferase activities of phospholipase D enzymes. | 1994 | Anal. Biochem. | pmid:8074295 |
| Naguib YM | A fluorometric method for measurement of peroxyl radical scavenging activities of lipophilic antioxidants. | 1998 | Anal. Biochem. | pmid:9882405 |
| Tsao FH et al. | The use of a multichannel scaling method to detect radioactive species in spread monolayers. | 1990 | Anal. Biochem. | pmid:2221346 |
| Joó F et al. | Complex hydrogenation/oxidation reactions of the water-soluble hydrogenation catalyst palladium di (sodium alizarinmonosulfonate) and details of homogeneous hydrogenation of lipids in isolated biomembranes and living cells. | 1991 | Anal. Biochem. | pmid:1651065 |
| Richieri GV and Kleinfeld AM | Continuous measurement of phospholipase A2 activity using the fluorescent probe ADIFAB. | 1995 | Anal. Biochem. | pmid:7485980 |
| Elmer-Dixon MM and Bowler BE | Rapid quantification of cardiolipin and DOPC lipid and vesicle concentration. | 2017 | Anal. Biochem. | pmid:28038882 |
| Stephan M et al. | Combining reflectometry and fluorescence microscopy: an assay for the investigation of leakage processes across lipid membranes. | 2014 | Anal. Chem. | pmid:24377291 |
| Marin V et al. | Stable Free-Standing Lipid Bilayer Membranes in Norland Optical Adhesive 81 Microchannels. | 2016 | Anal. Chem. | pmid:27351219 |
| Chen SY et al. | One-Step Detection of Major Lipid Components in Submicroliter Volumes of Unpurified Liposome and Cell Suspensions. | 2016 | Anal. Chem. | pmid:27337108 |
| Nguyen TT et al. | Comparison of the energetics of avidin, streptavidin, neutrAvidin, and anti-biotin antibody binding to biotinylated lipid bilayer examined by second-harmonic generation. | 2012 | Anal. Chem. | pmid:22122646 |
| Nguyen TT and Conboy JC | High-throughput screening of drug-lipid membrane interactions via counter-propagating second harmonic generation imaging. | 2011 | Anal. Chem. | pmid:21696170 |
| Wang C and Lucy CA | Oligomerized phospholipid bilayers as semipermanent coatings in capillary electrophoresis. | 2005 | Anal. Chem. | pmid:15801732 |
| Sly KL and Conboy JC | Determination of multivalent protein-ligand binding kinetics by second-harmonic correlation spectroscopy. | 2014 | Anal. Chem. | pmid:25314127 |
| Phillips KS et al. | Stable and fluid ethylphosphocholine membranes in a poly(dimethylsiloxane) microsensor for toxin detection in flooded waters. | 2005 | Anal. Chem. | pmid:15859616 |
| Mohamadi S et al. | Electrochemical screening of biomembrane-active compounds in water. | 2014 | Anal. Chim. Acta | pmid:24528664 |
| Basit H et al. | Aqueous-filled polymer microcavity arrays: versatile & stable lipid bilayer platforms offering high lateral mobility to incorporated membrane proteins. | 2015 | Analyst | pmid:25798456 |
| Wang F et al. | Profiling Metal Oxides with Lipids: Magnetic Liposomal Nanoparticles Displaying DNA and Proteins. | 2016 | Angew. Chem. Int. Ed. Engl. | pmid:27539511 |
| Saraogi I et al. | Synthetic alpha-helix mimetics as agonists and antagonists of islet amyloid polypeptide aggregation. | 2010 | Angew. Chem. Int. Ed. Engl. | pmid:20029853 |
| Koçer A et al. | Rationally designed chemical modulators convert a bacterial channel protein into a pH-sensory valve. | 2006 | Angew. Chem. Int. Ed. Engl. | pmid:16586527 |
| Michel R et al. | Internalization of silica nanoparticles into fluid liposomes: formation of interesting hybrid colloids. | 2014 | Angew. Chem. Int. Ed. Engl. | pmid:25257684 |
| Schuy S et al. | Coiled-coil lipopeptides mimicking the prehairpin intermediate of glycoprotein gp41. | 2009 | Angew. Chem. Int. Ed. Engl. | pmid:19090512 |
| Fornai F et al. | Striatal postsynaptic ultrastructural alterations following methylenedioxymethamphetamine administration. | 2002 | Ann. N. Y. Acad. Sci. | pmid:12105114 |
| Parisot J et al. | Molecular mechanism of target recognition by subtilin, a class I lanthionine antibiotic. | 2008 | Antimicrob. Agents Chemother. | pmid:17999970 |
| Paiva AD et al. | Role of lipid II and membrane thickness in the mechanism of action of the lantibiotic bovicin HC5. | 2011 | Antimicrob. Agents Chemother. | pmid:21876041 |
| Esnault C et al. | Another example of enzymatic promiscuity: the polyphosphate kinase of Streptomyces lividans is endowed with phospholipase D activity. | 2017 | Appl. Microbiol. Biotechnol. | pmid:27488682 |
| Angelova A et al. | Interaction of the peptide antibiotic alamethicin with bilayer- and non-bilayer-forming lipids: influence of increasing alamethicin concentration on the lipids supramolecular structures. | 2000 | Arch. Biochem. Biophys. | pmid:10871049 |
| Ahn T et al. | Effects of lipids on the interaction of SecA with model membranes. | 2001 | Arch. Biochem. Biophys. | pmid:11673860 |
| Thérond P et al. | Copper oxidation of in vitro dioleolylphosphatidylcholine-enriched high-density lipoproteins: physicochemical features and cholesterol effluxing capacity. | 1999 | Arch. Biochem. Biophys. | pmid:9917338 |
| Wong FM et al. | Electrostatically mediated interactions between cationic lipid-DNA particles and an anionic surface. | 1999 | Arch. Biochem. Biophys. | pmid:10334860 |
| Li QT and Das NP | Comparison of the effects of cholesterol and oxysterols on phospholipid bilayer microheterogeneity: a study of fluorescence lifetime distributions. | 1994 | Arch. Biochem. Biophys. | pmid:7986094 |
| Streicher-Scott J et al. | The reconstituted mitochondrial adenine nucleotide translocator: effects of lipid polymorphism. | 1994 | Arch. Biochem. Biophys. | pmid:7986102 |
| Kar P et al. | mu-Calpain mediated cleavage of the Na+/Ca2+ exchanger in isolated mitochondria under A23187 induced Ca2+ stimulation. | 2009 | Arch. Biochem. Biophys. | pmid:19094959 |
| Grataroli R et al. | Phospholipase A2 activity of rat stomach. | 1987 | Arch. Biochem. Biophys. | pmid:3116941 |
| Efrat M et al. | Di-oleoyl phosphatidylcholine (PC-18:1) stimulates paraoxonase 1 (PON1) enzymatic and biological activities: in vitro and in vivo studies. | 2009 | Atherosclerosis | pmid:18585720 |
| Jaschonek S et al. | Intramolecular structural parameters are key modulators of the gel-liquid transition in coarse grained simulations of DPPC and DOPC lipid bilayers. | 2018 | Biochem. Biophys. Res. Commun. | pmid:29101041 |
| Follenius-Wund A et al. | Conformational adaptation of annexin V upon binding to liposomes: a time-resolved fluorescence study. | 1997 | Biochem. Biophys. Res. Commun. | pmid:9168971 |
| Yoshikawa K et al. | Unique electronic property of a Langmuir-Blodgett film of dioleyl lecithin deposited on a porous membrane. | 1985 | Biochem. Biophys. Res. Commun. | pmid:4084294 |
| Hansen AS et al. | Bulk properties of the lipid bilayer are not essential for the thermal stability of Na,K-ATPase from shark rectal gland or pig kidney. | 2011 | Biochem. Biophys. Res. Commun. | pmid:21352812 |
| Potvin-Fournier K et al. | Membrane fluidity is a driving force for recoverin myristoyl immobilization in zwitterionic lipids. | 2017 | Biochem. Biophys. Res. Commun. | pmid:28684313 |
| Niederstadt M et al. | Binding of anti-trifluoroacetyl antibodies to isolated hepatocytes observed by digital fluorescence microscopy. | 1994 | Biochem. Biophys. Res. Commun. | pmid:8166745 |
| Debnath D et al. | Phospholipid assisted folding of a denatured heme protein: effect of phosphatidylethanolamine. | 2003 | Biochem. Biophys. Res. Commun. | pmid:12589809 |
| Heitz F and Spach G | Ionic channels of some glycine-rich synthetic polypeptides. | 1982 | Biochem. Biophys. Res. Commun. | pmid:6284141 |
| Taniyama Y et al. | Cloning and expression of a novel lysophospholipase which structurally resembles lecithin cholesterol acyltransferase. | 1999 | Biochem. Biophys. Res. Commun. | pmid:10092508 |
| Iwabuchi S et al. | Transport of actin-decorated liposomes along myosin molecules in vitro. | 2012 | Biochem. Biophys. Res. Commun. | pmid:22575445 |
| Epand RM and Epand RF | Factors contributing to the fusogenic potency of foamy virus. | 2001 | Biochem. Biophys. Res. Commun. | pmid:11409874 |
| Al-Momani L et al. | A lipid dependence in the formation of twin ion channels. | 2005 | Biochem. Biophys. Res. Commun. | pmid:15670789 |
| Chen Y et al. | Two-dimensional crystallization of a small heat shock protein HSP16.3 on lipid layer. | 2003 | Biochem. Biophys. Res. Commun. | pmid:14521918 |
| Menichetti R et al. | Efficient potential of mean force calculation from multiscale simulations: Solute insertion in a lipid membrane. | 2018 | Biochem. Biophys. Res. Commun. | pmid:28870809 |
| Sletten A et al. | Surface features of the lipid droplet mediate perilipin 2 localization. | 2014 | Biochem. Biophys. Res. Commun. | pmid:25172666 |
| Ho RJ et al. | Destabilization of target-sensitive immunoliposomes by antigen binding--a rapid assay for virus. | 1986 | Biochem. Biophys. Res. Commun. | pmid:3017345 |
| He B et al. | Increased cellular uptake of peptide-modified PEGylated gold nanoparticles. | 2017 | Biochem. Biophys. Res. Commun. | pmid:28993197 |
| Whyte BS et al. | Amphotericin B and Nystatin show different activities on sterol-free vesicles. | 1989 | Biochem. Biophys. Res. Commun. | pmid:2818579 |
| Sindelar P and Valtersson C | A dolichol acyltransferase present in rat and human postheparin plasma. | 1992 | Biochem. Cell Biol. | pmid:1449712 |
| Shivanna BD and Rowe ES | Preservation of the native structure and function of Ca2+-ATPase from sarcoplasmic reticulum: solubilization and reconstitution by new short-chain phospholipid detergent 1,2-diheptanoyl-sn-phosphatidylcholine. | 1997 | Biochem. J. | pmid:9230138 |
| Cyr N et al. | The hydrophobic region of the peroxin 14: requirements for association with a glycosome mimetic membrane. | 2018 | Biochem. J. | pmid:29259081 |
| Juhasz J et al. | Fluorescent probe partitioning in giant unilamellar vesicles of 'lipid raft' mixtures. | 2010 | Biochem. J. | pmid:20642452 |
| Chen SG et al. | Phosphatidylcholine-dependent protein kinase C activation. Effects of cis-fatty acid and diacylglycerol on synergism, autophosphorylation and Ca(2+)-dependency. | 1992 | Biochem. J. | pmid:1599399 |
| Sharpe M et al. | Fatty acids as modulators of cytochrome c oxidase in proteoliposomes. | 1996 | Biochem. J. | pmid:8973566 |
| Geisse NA et al. | Targeting of Helicobacter pylori vacuolating toxin to lipid raft membrane domains analysed by atomic force microscopy. | 2004 | Biochem. J. | pmid:15128269 |
| Kahya N | Light on fluorescent lipids in rafts: a lesson from model membranes. | 2010 | Biochem. J. | pmid:20795949 |
| Kinkaid AR and Wilton DC | Enhanced hydrolysis of phosphatidylcholine by human group II non-pancreatic secreted phospholipase A2 as a result of interfacial activation by specific anions. Potential role of cholesterol sulphate. | 1995 | Biochem. J. | pmid:7772034 |
| Dalton KA et al. | Anionic phospholipids decrease the rate of slippage on the Ca(2+)-ATPase of sarcoplasmic reticulum. | 1999 | Biochem. J. | pmid:10455031 |
| Tanfani F et al. | The interaction of phospholipid bilayers with pig heart AMP deaminase: Fourier-transform infrared spectroscopic and kinetic studies. | 1993 | Biochem. J. | pmid:8489518 |
| MartÃn M and de Mendoza D | Regulation of Bacillus subtilis DesK thermosensor by lipids. | 2013 | Biochem. J. | pmid:23356219 |
| ter Beest MB et al. | Reconstitution of proteolipid protein: some properties and its role in interlamellar attachment. | 1994 | Biochem. J. | pmid:7516154 |
| Verkade HJ et al. | Differential hepatic processing and biliary secretion of head-group and acyl chains of liposomal phosphatidylcholines. | 1991 | Biochem. J. | pmid:2018469 |
| Torrent M et al. | Ribonucleases as a host-defence family: evidence of evolutionarily conserved antimicrobial activity at the N-terminus. | 2013 | Biochem. J. | pmid:23962023 |
| Polozov IV et al. | Mixing rates can markedly affect the kinetics of peptide-induced leakage from liposomes. | 1994 | Biochem. Mol. Biol. Int. | pmid:7804132 |
| Kinkaid AR and Wilton DC | The hydrolysis of phosphatidyl-alcohols by phospholipases A2: effect of head group size and polarity. | 1997 | Biochem. Pharmacol. | pmid:9393676 |