12-hydroxy-5,8,10-heptadecatrienoic acid

12-hydroxy-5,8,10-heptadecatrienoic acid is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 466 references associated with 12-hydroxy-5,8,10-heptadecatrienoic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.

Here are additional resources we collected from PubChem and MeSH for 12-hydroxy-5,8,10-heptadecatrienoic acid

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 12-hydroxy-5,8,10-heptadecatrienoic acid

MeSH term MeSH ID Detail
Kidney Failure, Chronic D007676 51 associated lipids
Mammary Neoplasms, Experimental D008325 67 associated lipids
Pleurisy D010998 20 associated lipids
Seizures D012640 87 associated lipids
Uremia D014511 33 associated lipids
Weight Loss D015431 56 associated lipids
Total 6

NCBI Entrez Crosslinks

All references with 12-hydroxy-5,8,10-heptadecatrienoic acid

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Authors Title Published Journal PubMed Link
pmid:
Fujimoto Y et al. Sphingomyelin inhibits platelet 12-lipoxygenase activity. 1999 Eur. J. Pharmacol. pmid:10478636
Margalit A et al. Regulation of in vivo prostaglandin biosynthesis by glutathione. 1999 Adv. Exp. Med. Biol. pmid:10667326
Plastaras JP et al. Xenobiotic-metabolizing cytochromes P450 convert prostaglandin endoperoxide to hydroxyheptadecatrienoic acid and the mutagen, malondialdehyde. 2000 J. Biol. Chem. pmid:10766802
Mezei Z et al. Platelet arachidonate cascade of migraineurs in the interictal phase. 2000 Platelets pmid:10938901
Camacho M and Vila L Transcellular formation of thromboxane A(2) in mixed incubations of endothelial cells and aspirin-treated platelets strongly depends on the prostaglandin I-synthase activity. 2000 Thromb. Res. pmid:10946089
Fujimoto Y et al. Tetrahydrobiopterin attenuates modulation of platelet 12-lipoxygenase and cyclooxygenase activities by nitric oxide. 2001 Nitric Oxide pmid:11178940
Shyue SK et al. Selective augmentation of prostacyclin production by combined prostacyclin synthase and cyclooxygenase-1 gene transfer. 2001 Circulation pmid:11319200
John H and Schlegel W Determination of the pK(a) of 12-S-hydroxyheptadecatrienoic acid by studies of its vial surface adsorption using high-performance liquid chromatography and liquid scintillation technique. 1999 Chem. Phys. Lipids pmid:11458961
John H and Schlegel W Thermodynamic and structural characterization of cis-trans isomerization of 12-(S)-hydroxy-(5Z, 8E, 10E)-heptadecatrienoic acid by high-performance liquid chromatography and gaschromatography-mass spectrometry. 1998 Chem. Phys. Lipids pmid:11458962
Beck-Speier I et al. Agglomerates of ultrafine particles of elemental carbon and TiO2 induce generation of lipid mediators in alveolar macrophages. 2001 Environ. Health Perspect. pmid:11544173
Vecino AM et al. Phospholipase A2 activity in platelets of patients with uremia. 2002 Platelets pmid:12487789
Fujimoto Y et al. Effects of endocrine disruptors on arachidonic acid metabolism in rabbit platelets. 2003 Toxicol. Appl. Pharmacol. pmid:12781627
Engels F et al. Effects of apocynin, a drug isolated from the roots of Picrorhiza kurroa, on arachidonic acid metabolism. 1992 FEBS Lett. pmid:1299626
O'Sullivan BP et al. Reduction of eicosanoid production by essential fatty acid depletion does not attenuate the inflammatory response induced by Pseudomonas aeruginosa pneumonia in rat lung. 1992 Prostaglandins Leukot. Essent. Fatty Acids pmid:1324504
Pruimboom WM et al. Eicosanoid production by density-defined human peritoneal macrophages during inflammation. 1992 Agents Actions pmid:1332454
Dannhardt G and Lehr M In-vitro evaluation of 5-lipoxygenase and cyclo-oxygenase inhibitors using bovine neutrophils and platelets and HPLC. 1992 J. Pharm. Pharmacol. pmid:1359057
Zijlstra FJ et al. Species differences in the pattern of eicosanoids produced by inflamed and non-inflamed tissue. 1992 Agents Actions pmid:1442338
Beck-Speier I et al. Sulfur-related air pollutants induce the generation of platelet-activating factor, 5-lipoxygenase- and cyclooxygenase-products in canine alveolar macrophages via activation of phospholipases A2. 2003 Prostaglandins Other Lipid Mediat. pmid:14518563
Gecse A and Telegdy G Captopril as a modifier of the arachidonate cascade of rat platelets. 1992 Agents Actions Suppl. pmid:1462859