12-hydroxy-5,8,10-heptadecatrienoic acid is a lipid of Fatty Acyls (FA) class.
We collected disease MeSH terms mapped to the references associated with 12-hydroxy-5,8,10-heptadecatrienoic acid
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Weight Loss | D015431 | 56 associated lipids |
| Uremia | D014511 | 33 associated lipids |
| Seizures | D012640 | 87 associated lipids |
| Pleurisy | D010998 | 20 associated lipids |
| Mammary Neoplasms, Experimental | D008325 | 67 associated lipids |
| Kidney Failure, Chronic | D007676 | 51 associated lipids |
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
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| Ishii Y et al. | Leukotriene B4 receptor type 2 (BLT2) enhances skin barrier function by regulating tight junction proteins. | 2016 | FASEB J. | pmid:26527063 |
| Yasuda D et al. | Helix 8 of leukotriene B4 type-2 receptor is required for the folding to pass the quality control in the endoplasmic reticulum. | 2009 | FASEB J. | pmid:19126593 |
| Matsunaga Y et al. | Leukotriene B4 receptor BLT2 negatively regulates allergic airway eosinophilia. | 2013 | FASEB J. | pmid:23603839 |
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| Fan SY et al. | The anti-inflammatory activities of an extract and compounds isolated from Platycladus orientalis (Linnaeus) Franco in vitro and ex vivo. | 2012 | J Ethnopharmacol | pmid:21619922 |
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| Liu M et al. | 12-Hydroxyheptadecatrienoic acid promotes epidermal wound healing by accelerating keratinocyte migration via the BLT2 receptor. | 2014 | J. Exp. Med. | pmid:24821912 |
| Gus-Brautbar Y and Panigrahy D | Time heals all wounds--but 12-HHT is faster. | 2014 | J. Exp. Med. | pmid:24890114 |
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| Graeber JE et al. | Effect of homocysteine and homocystine on platelet and vascular arachidonic acid metabolism. | 1982 | Pediatr. Res. | pmid:6808450 |
| Stuart MJ and Allen JB | Arachidonic acid metabolism in the neonatal platelet. | 1982 | Pediatrics | pmid:6804924 |
| Csanyi G et al. | Lack of endothelium-derived hyperpolarizing factor (EDHF) up-regulation in endothelial dysfunction in aorta in diabetic rats. | 2007 Jul-Aug | Pharmacol Rep | pmid:17901574 |
| Csányi G et al. | Effects of 3-aminopyridine-induced seizures on platelet eicosanoid synthesis. | 2008 May-Jun | Pharmacol Rep | pmid:18622059 |
| Abbate R et al. | Activity of dipyrone on intraplatelet arachidonic acid metabolism: an in vitro study. | 1989 Jan-Feb | Pharmacol. Res. | pmid:2726664 |
| Vecino AM et al. | Phospholipase A2 activity in platelets of patients with uremia. | 2002 | Platelets | pmid:12487789 |
| Mezei Z et al. | Platelet arachidonate cascade of migraineurs in the interictal phase. | 2000 | Platelets | pmid:10938901 |
| Pataki I et al. | In vivo effects of isatin on rat platelet eicosanoids. | 2005 | Platelets | pmid:15763895 |
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| Stenson WF et al. | Metabolism of exogenous arachidonic acid by murine macrophage-like tumor cell lines. | 1981 | Prostaglandins | pmid:6803301 |
| Sadowitz PD et al. | The platelet cyclooxygenase metabolite 12-L-hydroxy-5, 8, 10-hepta-decatrienoic acid (HHT) may modulate primary hemostasis by stimulating prostacyclin production. | 1987 | Prostaglandins | pmid:3124219 |
| Siegel MI et al. | The production of 5-HETE and leukotriene B in rat neutrophils from carrageenan pleural exudates. | 1981 | Prostaglandins | pmid:6259697 |
| Greenwald JE et al. | Argentation thin layer chromatography of arachidonic acid metabolites isolated from human platelets. | 1981 | Prostaglandins | pmid:7208953 |
| Muller M and Sorrell TC | Inhibition of the human platelet cyclooxygenase response by the naturally occurring phenazine derivative, 1-hydroxyphenazine. | 1995 Nov-Dec | Prostaglandins | pmid:8838240 |
| Morrison AR et al. | Thromboxane A2 is the major arachidonic acid metabolite of human cortical hydronephrotic tissue. | 1981 | Prostaglandins | pmid:6894498 |
| She HS et al. | Metabolism of prostaglandin endoperoxide by microsomes from cat lung. | 1981 | Prostaglandins | pmid:6894797 |
| Sweeney FJ et al. | The use of 12-hydroxyheptadecatrienoic acid (HHT) as an HPLC/spectrophotometric marker for cyclooxygenase pathway activity in resident rat peritoneal cells. | 1987 | Prostaglandins Leukot Med | pmid:3033686 |
| Hall ER et al. | Immobilization of catalytically active thromboxane synthase. | 1988 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:3406040 |
| Sakuma S et al. | Effects of daphnodorin A, B and C, new flavans isolated from traditional Chinese medicine, on the 12-lipoxygenase and cyclooxygenase metabolism of arachidonic acid in rabbit platelets. | 1998 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:9578153 |
| Fujimoto Y et al. | Comparison of the effects of nitric oxide and peroxynitrite on the 12-lipoxygenase and cyclooxygenase metabolism of arachidonic acid in rabbit platelets. | 1998 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:9774172 |