12-hydroxy-5,8,10-heptadecatrienoic acid

12-hydroxy-5,8,10-heptadecatrienoic acid is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 466 references associated with 12-hydroxy-5,8,10-heptadecatrienoic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.

Here are additional resources we collected from PubChem and MeSH for 12-hydroxy-5,8,10-heptadecatrienoic acid

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 12-hydroxy-5,8,10-heptadecatrienoic acid

MeSH term MeSH ID Detail
Weight Loss D015431 56 associated lipids
Uremia D014511 33 associated lipids
Seizures D012640 87 associated lipids
Pleurisy D010998 20 associated lipids
Mammary Neoplasms, Experimental D008325 67 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Total 6

NCBI Entrez Crosslinks

All references with 12-hydroxy-5,8,10-heptadecatrienoic acid

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Authors Title Published Journal PubMed Link
Sakuma S et al. Perfluorinated carboxylic acids inhibit cyclooxygenase pathway more potently than 12-lipoxygenase pathway in rat platelets. 2010 Oct-Dec Prostaglandins Leukot. Essent. Fatty Acids pmid:20678909
O'Sullivan BP et al. Reduction of eicosanoid production by essential fatty acid depletion does not attenuate the inflammatory response induced by Pseudomonas aeruginosa pneumonia in rat lung. 1992 Prostaglandins Leukot. Essent. Fatty Acids pmid:1324504
Fujimoto Y et al. Comparison of the effects of nitric oxide and peroxynitrite on the 12-lipoxygenase and cyclooxygenase metabolism of arachidonic acid in rabbit platelets. 1998 Prostaglandins Leukot. Essent. Fatty Acids pmid:9774172
Eling T et al. Separation of prostaglandins, thromboxane, hydroxy fatty acids and arachidonic acid by high pressure liquid chromatography. 1980 Prostaglandins Med pmid:6779300
Vincent JE et al. Determination of the formation of thromboxane B2 (TxB2), 12L-hydroxy-5,8,10 heptadecatrienoic acid (HHT) and 12L-hydroxy-5,8,10,14 eicosatrienoic acid (HETE) from arachidonic acid and of the TxB2 :HHT, TxB2 :HETE and (TxB2 +HHT) :HETE ratio in human platelets. Possible use in diagnostic purposes. 1980 Prostaglandins Med pmid:7413847
John H et al. Development and review of radioimmunoassay of 12-S-hydroxyheptadecatrienoic acid. 1998 Prostaglandins Other Lipid Mediat. pmid:9785378
Beck-Speier I et al. Sulfur-related air pollutants induce the generation of platelet-activating factor, 5-lipoxygenase- and cyclooxygenase-products in canine alveolar macrophages via activation of phospholipases A2. 2003 Prostaglandins Other Lipid Mediat. pmid:14518563
Fujimoto Y et al. High density lipoprotein inhibits platelet 12-lipoxygenase activity. 1994 Res. Commun. Mol. Pathol. Pharmacol. pmid:7827811
Li NY [Selective inhibitory effects of flufenamic acid on metabolic pathways of arachidonate 5-lipoxygenase and cyclooxygenase]. 1989 Sheng Li Ke Xue Jin Zhan pmid:2561227
Rousson D et al. Acute myocardial infarction: measurement of arachidonate end-products in whole blood as an index of platelet cyclo-oxygenase activity in vivo. 1987 Thromb. Res. pmid:3122356
Beving H et al. Effects on cyclo-oxygenase of low and high dose aspirin. 1990 Thromb. Res. pmid:2122535
Vericel E et al. Platelets and aging. I--Aggregation, arachidonate metabolism and antioxidant status. 1988 Thromb. Res. pmid:3129819
Beving H et al. Inter-individual variations of the effect of low dose aspirin regime on platelet cyclooxygenase activity. 1994 Thromb. Res. pmid:8029807
Camacho M and Vila L Transcellular formation of thromboxane A(2) in mixed incubations of endothelial cells and aspirin-treated platelets strongly depends on the prostaglandin I-synthase activity. 2000 Thromb. Res. pmid:10946089
Guichardant M et al. Effects of 9, 12, 15-octadecatrien-6-ynoic acid on the metabolism of arachidonic acid in platelets and on platelet aggregation. 1992 Thromb. Res. pmid:1636161
Driss F et al. Inhibition of platelet aggregation and thromboxane synthesis after intake of small amount of icosapentaenoic acid. 1984 Thromb. Res. pmid:6098051
Fujimoto Y et al. Effects of endocrine disruptors on arachidonic acid metabolism in rabbit platelets. 2003 Toxicol. Appl. Pharmacol. pmid:12781627
Stuart MJ The effect of irradiation on platelet arachidonic acid metabolism. 1983 Mar-Apr Transfusion pmid:6404019
Yue TL et al. [Effects of anisodamine on the metabolism of arachidonic acid by washed rat platelets]. 1989 Yao Xue Xue Bao pmid:2618712
Tong L and Yue TL [Effect of dauricine on rat and human platelet aggregation and metabolism of arachidonic acid in washed rat platelets]. 1989 Yao Xue Xue Bao pmid:2801142
Yue TL et al. [Effects of anisodamine on the metabolism of arachidonic acid by rat pleural neutrophils]. 1988 Yao Xue Xue Bao pmid:2855772
Yg G et al. [Effect of Allium cepa L. var. agrogatum Don and Allium macrostemon Bunge on arachidonic acid metabolism]. 1988 Yao Xue Xue Bao pmid:3400480
Yue TL and Tong L [Effects of dauricine on the metabolism of arachidonic acid in rat pleural neutrophils]. 1989 Zhongguo Yao Li Xue Bao pmid:2558500