12-hydroxy-5,8,10-heptadecatrienoic acid

12-hydroxy-5,8,10-heptadecatrienoic acid is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 466 references associated with 12-hydroxy-5,8,10-heptadecatrienoic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.

Here are additional resources we collected from PubChem and MeSH for 12-hydroxy-5,8,10-heptadecatrienoic acid

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 12-hydroxy-5,8,10-heptadecatrienoic acid

MeSH term MeSH ID Detail
Weight Loss D015431 56 associated lipids
Uremia D014511 33 associated lipids
Seizures D012640 87 associated lipids
Pleurisy D010998 20 associated lipids
Mammary Neoplasms, Experimental D008325 67 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Total 6

NCBI Entrez Crosslinks

All references with 12-hydroxy-5,8,10-heptadecatrienoic acid

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Authors Title Published Journal PubMed Link
Hofmann U et al. Measurement of 12(S)-hydroxy-5Z,8E,10E-heptadecatrienoic acid and its metabolite 12-oxo-5Z,8E,10E-heptadecatrienoic acid in human plasma by gas chromatography/negative ion chemical ionization mass spectrometry. 1990 Anal. Biochem. pmid:2281869
Lee JW et al. 12(S)-Hydroxyheptadeca-5Z,8E,10E-trienoic acid suppresses UV-induced IL-6 synthesis in keratinocytes, exerting an anti-inflammatory activity. 2012 Exp. Mol. Med. pmid:22391335
Fan SY et al. The anti-inflammatory activities of an extract and compounds isolated from Platycladus orientalis (Linnaeus) Franco in vitro and ex vivo. 2012 J Ethnopharmacol pmid:21619922
O'Keefe SF et al. Trans n-3 eicosapentaenoic and docosahexaenoic acid isomers exhibit different inhibitory effects on arachidonic acid metabolism in human platelets compared to the respective cis fatty acids. 1990 J. Lipid Res. pmid:2144870
Beving H et al. Effects on cyclo-oxygenase of low and high dose aspirin. 1990 Thromb. Res. pmid:2122535
Bauer J et al. Arzanol, a prenylated heterodimeric phloroglucinyl pyrone, inhibits eicosanoid biosynthesis and exhibits anti-inflammatory efficacy in vivo. 2011 Biochem. Pharmacol. pmid:20933508
Sakuma S et al. Perfluorinated carboxylic acids inhibit cyclooxygenase pathway more potently than 12-lipoxygenase pathway in rat platelets. 2010 Oct-Dec Prostaglandins Leukot. Essent. Fatty Acids pmid:20678909
Koeberle A et al. Myrtucommulone, a natural acylphloroglucinol, inhibits microsomal prostaglandin E(2) synthase-1. 2009 Br. J. Pharmacol. pmid:19298395
Yasuda D et al. Helix 8 of leukotriene B4 type-2 receptor is required for the folding to pass the quality control in the endoplasmic reticulum. 2009 FASEB J. pmid:19126593
Duncan EM and Lloyd JV Interference caused by acid extraction in the study of diacylglycerol in platelets. 1991 Blood Coagul. Fibrinolysis pmid:1893058
Csányi G et al. Effects of 3-aminopyridine-induced seizures on platelet eicosanoid synthesis. 2008 May-Jun Pharmacol Rep pmid:18622059
Okuno T et al. 12(S)-Hydroxyheptadeca-5Z, 8E, 10E-trienoic acid is a natural ligand for leukotriene B4 receptor 2. 2008 J. Exp. Med. pmid:18378794
Chevy F et al. A unique pool of free arachidonate serves as substrate for both cyclooxygenase and lipoxygenase in platelets. 1991 Lipids pmid:1819690
Csanyi G et al. Lack of endothelium-derived hyperpolarizing factor (EDHF) up-regulation in endothelial dysfunction in aorta in diabetic rats. 2007 Jul-Aug Pharmacol Rep pmid:17901574
Li X et al. Activation of extracellular signal-regulated kinase by 12-hydroxyheptadecatrienoic acid in prostate cancer PC3 cells. 2007 Arch. Biochem. Biophys. pmid:17880908
Espada CE et al. Effect of Chia oil (Salvia Hispanica) rich in omega-3 fatty acids on the eicosanoid release, apoptosis and T-lymphocyte tumor infiltration in a murine mammary gland adenocarcinoma. 2007 Prostaglandins Leukot. Essent. Fatty Acids pmid:17618100
Fujimoto Y et al. Monochloramine potently inhibits arachidonic acid metabolism in rat platelets. 2006 Biochem. Biophys. Res. Commun. pmid:16615995
Stenke L et al. Deficient lipoxin synthesis: a novel platelet dysfunction in myeloproliferative disorders with special reference to blastic crisis of chronic myelogenous leukemia. 1991 Blood pmid:1659470
Guichardant M et al. Effects of 9, 12, 15-octadecatrien-6-ynoic acid on the metabolism of arachidonic acid in platelets and on platelet aggregation. 1992 Thromb. Res. pmid:1636161
Forsell PK et al. Polychlorinated biphenyls induce arachidonic acid release in human platelets in a tamoxifen sensitive manner via activation of group IVA cytosolic phospholipase A2-alpha. 2005 Biochem. Pharmacol. pmid:16290172