12-hydroxy-5,8,10-heptadecatrienoic acid

12-hydroxy-5,8,10-heptadecatrienoic acid is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 466 references associated with 12-hydroxy-5,8,10-heptadecatrienoic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.

Here are additional resources we collected from PubChem and MeSH for 12-hydroxy-5,8,10-heptadecatrienoic acid

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 12-hydroxy-5,8,10-heptadecatrienoic acid

MeSH term MeSH ID Detail
Uremia D014511 33 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Pleurisy D010998 20 associated lipids
Mammary Neoplasms, Experimental D008325 67 associated lipids
Seizures D012640 87 associated lipids
Weight Loss D015431 56 associated lipids
Total 6

NCBI Entrez Crosslinks

All references with 12-hydroxy-5,8,10-heptadecatrienoic acid

Download all related citations
Per page 10 20 50 100 | Total 123
Authors Title Published Journal PubMed Link
John H and Schlegel W Thermodynamic and structural characterization of cis-trans isomerization of 12-(S)-hydroxy-(5Z, 8E, 10E)-heptadecatrienoic acid by high-performance liquid chromatography and gaschromatography-mass spectrometry. 1998 Chem. Phys. Lipids pmid:11458962
Shyue SK et al. Selective augmentation of prostacyclin production by combined prostacyclin synthase and cyclooxygenase-1 gene transfer. 2001 Circulation pmid:11319200
Guichardant M et al. Metabolism of endogenous arachidonic acid in weakly activated platelets. Absence of leukocyte cooperative products in whole blood. 1989 Eicosanoids pmid:2516743
Hecker M and Ullrich V 12(S)-Hydroxy-5,8,10 (Z,E,E)-heptadecatrienoic acid (HHT) is preferentially metabolized to its 12-keto derivative by human erythrocytes in vitro. 1988 Eicosanoids pmid:3272822
Beck-Speier I et al. Agglomerates of ultrafine particles of elemental carbon and TiO2 induce generation of lipid mediators in alveolar macrophages. 2001 Environ. Health Perspect. pmid:11544173
Höhl W et al. Mass determination of 15-hydroxyprostaglandin dehydrogenase from human placenta and kinetic studies with (5Z, 8E, 10E, 12S)-12-hydroxy-5,8,10-heptadecatrienoic acid as substrate. 1993 Eur. J. Biochem. pmid:8508808
Tawata M et al. Anti-platelet action of isoliquiritigenin, an aldose reductase inhibitor in licorice. 1992 Eur. J. Pharmacol. pmid:1555643
Mezei Z et al. Platelet eicosanoids and the effect of captopril in blood pressure regulation. 1997 Eur. J. Pharmacol. pmid:9527508
Tornhamre S et al. Effects of sulfasalazine and a sulfasalazine analogue on the formation of lipoxygenase and cyclooxygenase products. 1989 Eur. J. Pharmacol. pmid:2572437
Fujimoto Y et al. Sphingomyelin inhibits platelet 12-lipoxygenase activity. 1999 Eur. J. Pharmacol. pmid:10478636
Lee JW et al. 12(S)-Hydroxyheptadeca-5Z,8E,10E-trienoic acid suppresses UV-induced IL-6 synthesis in keratinocytes, exerting an anti-inflammatory activity. 2012 Exp. Mol. Med. pmid:22391335
Ishii Y et al. Leukotriene B4 receptor type 2 (BLT2) enhances skin barrier function by regulating tight junction proteins. 2016 FASEB J. pmid:26527063
Yasuda D et al. Helix 8 of leukotriene B4 type-2 receptor is required for the folding to pass the quality control in the endoplasmic reticulum. 2009 FASEB J. pmid:19126593
Matsunaga Y et al. Leukotriene B4 receptor BLT2 negatively regulates allergic airway eosinophilia. 2013 FASEB J. pmid:23603839
Engels F et al. Effects of apocynin, a drug isolated from the roots of Picrorhiza kurroa, on arachidonic acid metabolism. 1992 FEBS Lett. pmid:1299626
Yokoyama C et al. Expression of human thromboxane synthase using a baculovirus system. 1993 FEBS Lett. pmid:8436233
Sumiya T et al. Effects of reactive oxygen species on arachidonic acid metabolism in rabbit platelets. 1993 Free Radic. Biol. Med. pmid:8359708
Johnsen SA et al. Conversion of arachidonic acid in human maternal and neonatal mononuclear leukocytes. 1983 Immunol. Lett. pmid:6411611
Köller M et al. Effect of the PAF-receptor antagonist SM-12502 on human platelets. 1996 Inflammation pmid:8926050
Engels F et al. Modulation of the release of 9-hydroxy-octadecadienoic acid and other fatty acid derived mediators from guinea-pig pulmonary macrophages. 1990 Int. J. Immunopharmacol. pmid:2329013