12-hydroxy-5,8,10-heptadecatrienoic acid

12-hydroxy-5,8,10-heptadecatrienoic acid is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 466 references associated with 12-hydroxy-5,8,10-heptadecatrienoic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.

Here are additional resources we collected from PubChem and MeSH for 12-hydroxy-5,8,10-heptadecatrienoic acid

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 12-hydroxy-5,8,10-heptadecatrienoic acid

MeSH term MeSH ID Detail
Uremia D014511 33 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Pleurisy D010998 20 associated lipids
Mammary Neoplasms, Experimental D008325 67 associated lipids
Seizures D012640 87 associated lipids
Weight Loss D015431 56 associated lipids
Total 6

NCBI Entrez Crosslinks

All references with 12-hydroxy-5,8,10-heptadecatrienoic acid

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Authors Title Published Journal PubMed Link
Graeber JE et al. Effect of homocysteine and homocystine on platelet and vascular arachidonic acid metabolism. 1982 Pediatr. Res. pmid:6808450
Stuart MJ and Allen JB Arachidonic acid metabolism in the neonatal platelet. 1982 Pediatrics pmid:6804924
Csanyi G et al. Lack of endothelium-derived hyperpolarizing factor (EDHF) up-regulation in endothelial dysfunction in aorta in diabetic rats. 2007 Jul-Aug Pharmacol Rep pmid:17901574
Csányi G et al. Effects of 3-aminopyridine-induced seizures on platelet eicosanoid synthesis. 2008 May-Jun Pharmacol Rep pmid:18622059
Abbate R et al. Activity of dipyrone on intraplatelet arachidonic acid metabolism: an in vitro study. 1989 Jan-Feb Pharmacol. Res. pmid:2726664
Vecino AM et al. Phospholipase A2 activity in platelets of patients with uremia. 2002 Platelets pmid:12487789
Mezei Z et al. Platelet arachidonate cascade of migraineurs in the interictal phase. 2000 Platelets pmid:10938901
Pataki I et al. In vivo effects of isatin on rat platelet eicosanoids. 2005 Platelets pmid:15763895
Panosian AG et al. [Action of adaptogens: cucurbitacin R diglucoside as a stimulator of arachidonic acid metabolism in the rat adrenal gland]. 1989 Mar-Apr Probl Endokrinol (Mosk) pmid:2544873
Stenson WF et al. Metabolism of exogenous arachidonic acid by murine macrophage-like tumor cell lines. 1981 Prostaglandins pmid:6803301
Sadowitz PD et al. The platelet cyclooxygenase metabolite 12-L-hydroxy-5, 8, 10-hepta-decatrienoic acid (HHT) may modulate primary hemostasis by stimulating prostacyclin production. 1987 Prostaglandins pmid:3124219
Siegel MI et al. The production of 5-HETE and leukotriene B in rat neutrophils from carrageenan pleural exudates. 1981 Prostaglandins pmid:6259697
Greenwald JE et al. Argentation thin layer chromatography of arachidonic acid metabolites isolated from human platelets. 1981 Prostaglandins pmid:7208953
Muller M and Sorrell TC Inhibition of the human platelet cyclooxygenase response by the naturally occurring phenazine derivative, 1-hydroxyphenazine. 1995 Nov-Dec Prostaglandins pmid:8838240
Morrison AR et al. Thromboxane A2 is the major arachidonic acid metabolite of human cortical hydronephrotic tissue. 1981 Prostaglandins pmid:6894498
She HS et al. Metabolism of prostaglandin endoperoxide by microsomes from cat lung. 1981 Prostaglandins pmid:6894797
Sweeney FJ et al. The use of 12-hydroxyheptadecatrienoic acid (HHT) as an HPLC/spectrophotometric marker for cyclooxygenase pathway activity in resident rat peritoneal cells. 1987 Prostaglandins Leukot Med pmid:3033686
Hall ER et al. Immobilization of catalytically active thromboxane synthase. 1988 Prostaglandins Leukot. Essent. Fatty Acids pmid:3406040
Sakuma S et al. Effects of daphnodorin A, B and C, new flavans isolated from traditional Chinese medicine, on the 12-lipoxygenase and cyclooxygenase metabolism of arachidonic acid in rabbit platelets. 1998 Prostaglandins Leukot. Essent. Fatty Acids pmid:9578153
Espada CE et al. Effect of Chia oil (Salvia Hispanica) rich in omega-3 fatty acids on the eicosanoid release, apoptosis and T-lymphocyte tumor infiltration in a murine mammary gland adenocarcinoma. 2007 Prostaglandins Leukot. Essent. Fatty Acids pmid:17618100