12-hydroxy-5,8,10-heptadecatrienoic acid

12-hydroxy-5,8,10-heptadecatrienoic acid is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 466 references associated with 12-hydroxy-5,8,10-heptadecatrienoic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.

Here are additional resources we collected from PubChem and MeSH for 12-hydroxy-5,8,10-heptadecatrienoic acid

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 12-hydroxy-5,8,10-heptadecatrienoic acid

MeSH term MeSH ID Detail
Uremia D014511 33 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Pleurisy D010998 20 associated lipids
Mammary Neoplasms, Experimental D008325 67 associated lipids
Seizures D012640 87 associated lipids
Weight Loss D015431 56 associated lipids
Total 6

NCBI Entrez Crosslinks

All references with 12-hydroxy-5,8,10-heptadecatrienoic acid

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Authors Title Published Journal PubMed Link
Li NY [Selective inhibitory effects of flufenamic acid on metabolic pathways of arachidonate 5-lipoxygenase and cyclooxygenase]. 1989 Sheng Li Ke Xue Jin Zhan pmid:2561227
Guichardant M et al. Metabolism of endogenous arachidonic acid in weakly activated platelets. Absence of leukocyte cooperative products in whole blood. 1989 Eicosanoids pmid:2516743
Tong L and Yue TL [Effect of dauricine on rat and human platelet aggregation and metabolism of arachidonic acid in washed rat platelets]. 1989 Yao Xue Xue Bao pmid:2801142
Engels W et al. Influence of a cytomegalovirus infection on functions and arachidonic acid metabolism of rat peritoneal macrophages. 1989 J. Leukoc. Biol. pmid:2540258
Yue TL et al. [Effects of anisodamine on the metabolism of arachidonic acid by rat pleural neutrophils]. 1988 Yao Xue Xue Bao pmid:2855772
Vericel E et al. Platelets and aging. I--Aggregation, arachidonate metabolism and antioxidant status. 1988 Thromb. Res. pmid:3129819
Yg G et al. [Effect of Allium cepa L. var. agrogatum Don and Allium macrostemon Bunge on arachidonic acid metabolism]. 1988 Yao Xue Xue Bao pmid:3400480
Hall ER et al. Immobilization of catalytically active thromboxane synthase. 1988 Prostaglandins Leukot. Essent. Fatty Acids pmid:3406040
Campbell PB and Tolson TA Modulation of human monocyte leukotactic responsiveness by thromboxane A2 and 12-hydroxyheptadecatrienoic acid (12-HHT). 1988 J. Leukoc. Biol. pmid:3422086
Hecker M and Ullrich V 12(S)-Hydroxy-5,8,10 (Z,E,E)-heptadecatrienoic acid (HHT) is preferentially metabolized to its 12-keto derivative by human erythrocytes in vitro. 1988 Eicosanoids pmid:3272822
Kouzan S et al. Stimulation of arachidonic acid metabolism by adherence of alveolar macrophages to a plastic substrate. Modulation by fetal bovine serum. 1988 Am. Rev. Respir. Dis. pmid:2827547
Rousson D et al. Acute myocardial infarction: measurement of arachidonate end-products in whole blood as an index of platelet cyclo-oxygenase activity in vivo. 1987 Thromb. Res. pmid:3122356
Sweeney FJ et al. The use of 12-hydroxyheptadecatrienoic acid (HHT) as an HPLC/spectrophotometric marker for cyclooxygenase pathway activity in resident rat peritoneal cells. 1987 Prostaglandins Leukot Med pmid:3033686
Leis HJ et al. Quantitative measurement of 5-, 12-, and 15-hydroxyeicosatetraenoic acid together with 12-hydroxyheptadecatrienoic acid by stable isotope dilution gas chromatography-negative ion chemical ionization-mass spectrometry. 1987 Anal. Biochem. pmid:3300415
Sadowitz PD et al. The platelet cyclooxygenase metabolite 12-L-hydroxy-5, 8, 10-hepta-decatrienoic acid (HHT) may modulate primary hemostasis by stimulating prostacyclin production. 1987 Prostaglandins pmid:3124219
Zulak IM et al. A fast, nondestructive purification scheme for prostaglandin H2 using a nonaqueous, bonded-phase high-performance liquid chromatography system. 1986 Anal. Biochem. pmid:3085539
Liu Y et al. 12-L-hydroxy-5,8,10-heptadecatrienoic acid (HHT) is an excellent substrate for NAD+-dependent 15-hydroxyprostaglandin dehydrogenase. 1985 Biochem. Biophys. Res. Commun. pmid:4004878
Halenda SP et al. Phorbol esters and oleoyl acetoyl glycerol enhance release of arachidonic acid in platelets stimulated by Ca2+ ionophore A23187. 1985 J. Biol. Chem. pmid:3930496
Kimura Y et al. Effects of stilbene derivatives on arachidonate metabolism in leukocytes. 1985 Biochim. Biophys. Acta pmid:3931689
Hamsten A et al. Shortened megakaryocyte-platelet regeneration time in young survivors of myocardial infarction. 1985 Am. Heart J. pmid:2866703