ISOBUTYRIC ACID

ISOBUTYRIC ACID is a lipid of Fatty Acyls (FA) class. Isobutyric acid is associated with abnormalities such as Atrophy, Muscular, Spinobulbar. The involved functions are known as Signal Transduction, Oxidation, Vmax, Metabolic Inhibition and Regulation. Isobutyric acid often locates in Cytoplasm, Plasma membrane, peroxisome, Mouse Embryonic Fibroblast and Protoplasm. The associated genes with ISOBUTYRIC ACID are Candidate Disease Gene, CDKN1A gene, MYC gene, E2F1 gene and HBP1 gene. The related lipids are butyrate, Butyrates, lipid structure, Fatty Acids and Propionate. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of ISOBUTYRIC ACID, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with ISOBUTYRIC ACID?

ISOBUTYRIC ACID is suspected in Atrophy, Muscular, Spinobulbar and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with ISOBUTYRIC ACID

MeSH term MeSH ID Detail
Body Weight D001835 333 associated lipids
Adenocarcinoma D000230 166 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Stomach Ulcer D013276 75 associated lipids
Hyperlipidemias D006949 73 associated lipids
Gastrointestinal Hemorrhage D006471 27 associated lipids
Malabsorption Syndromes D008286 16 associated lipids
Werner Syndrome D014898 4 associated lipids
Myoclonic Epilepsies, Progressive D020191 3 associated lipids
Total 10

PubChem Associated disorders and diseases

What pathways are associated with ISOBUTYRIC ACID

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with ISOBUTYRIC ACID?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with ISOBUTYRIC ACID?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with ISOBUTYRIC ACID?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with ISOBUTYRIC ACID?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with ISOBUTYRIC ACID?

Knock-out

Knock-out are used in the study 'G1/S arrest induced by histone deacetylase inhibitor sodium butyrate in E1A + Ras-transformed cells is mediated through down-regulation of E2F activity and stabilization of beta-catenin.' (Abramova MV et al., 2006).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

NCBI Entrez Crosslinks

All references with ISOBUTYRIC ACID

Download all related citations
Per page 10 20 50 100 | Total 515
Authors Title Published Journal PubMed Link
Ayshamgul H et al. [1H-MRS metabonomic analysis of plasma samples of esophageal cancer patients based on different pattern recognition]. 2010 Zhonghua Zhong Liu Za Zhi pmid:21122383
Ayxiam H et al. [Metabonomic variation of esophageal cancer within different ethnic groups in Xinjiang, China]. 2009 Zhonghua Yu Fang Yi Xue Za Zhi pmid:19954070
DU ZH et al. [Mechanism of leukemia cell apoptosis induced by sodium butyrate activating TRAIL pathway]. 2009 Zhongguo Shi Yan Xue Ye Xue Za Zhi pmid:19379558
He L et al. Possible mechanism for the regulation of glucose on proliferation, inhibition and apoptosis of colon cancer cells induced by sodium butyrate. 2007 World J. Gastroenterol. pmid:17663521
Larauche M et al. Stress-induced visceral analgesia assessed non-invasively in rats is enhanced by prebiotic diet. 2012 World J. Gastroenterol. pmid:22294825
Yu HQ and Fang HH Acidification of mid- and high-strength dairy wastewaters. 2001 Water Res. pmid:11561632
Yu HQ and Fang HH Acidogenesis of gelatin-rich wastewater in an upflow anaerobic reactor: influence of pH and temperature. 2003 Water Res. pmid:12465788
Jiang S et al. Biological short-chain fatty acids (SCFAs) production from waste-activated sludge affected by surfactant. 2007 Water Res. pmid:17499838
Gallert C et al. Scale-up of anaerobic digestion of the biowaste fraction from domestic wastes. 2003 Water Res. pmid:12598207
Hu ZH and Yu HQ Anaerobic digestion of cattail by rumen cultures. 2006 Waste Manag pmid:16198552
Morris GP et al. A functional model for extracellular gastric mucus in the rat. 1984 Virchows Arch., B, Cell Pathol. pmid:6148803
Noireau F et al. Trypanosoma cruzi: adaptation to its vectors and its hosts. 2009 Mar-Apr Vet. Res. pmid:19250627
Seeling K et al. On the effects of Fusarium toxin contaminated wheat and wheat chaff on nutrient utilisation and turnover of deoxynivalenol and zearalenone in vitro (Rusitec). 2006 Toxicol In Vitro pmid:16321500
Sun H et al. Complete genome sequence of Desulfarculus baarsii type strain (2st14). 2010 Stand Genomic Sci pmid:21304732
Spring S et al. Complete genome sequence of Desulfotomaculum acetoxidans type strain (5575). 2009 Stand Genomic Sci pmid:21304664
Göker M et al. Complete genome sequence of Odoribacter splanchnicus type strain (1651/6). 2011 Stand Genomic Sci pmid:21677857
Pati A et al. Complete genome sequence of Bacteroides helcogenes type strain (P 36-108). 2011 Stand Genomic Sci pmid:21475586
Brambilla E et al. Complete genome sequence of Methanoplanus petrolearius type strain (SEBR 4847). 2010 Stand Genomic Sci pmid:21304750
Pitluck S et al. Complete genome sequence of Thermosediminibacter oceani type strain (JW/IW-1228P). 2010 Stand Genomic Sci pmid:21304740
Djao OD et al. Complete genome sequence of Syntrophothermus lipocalidus type strain (TGB-C1). 2010 Stand Genomic Sci pmid:21304731
Labutti K et al. Permanent draft genome sequence of Dethiosulfovibrio peptidovorans type strain (SEBR 4207). 2010 Stand Genomic Sci pmid:21304695
Vyalikh A et al. Evidence of microphase separation in controlled pore glasses. 2005 Solid State Nucl Magn Reson pmid:16061359
Caroprese A et al. HS-SPME-GC-MS analysis of body odor to test the efficacy of foot deodorant formulations. 2009 Skin Res Technol pmid:19832965
Parker DB et al. Recovery of agricultural odors and odorous compounds from polyvinyl fluoride film bags. 2010 Sensors (Basel) pmid:22163671
Kulshreshtha NM et al. Usefulness of organic acid produced by Exiguobacterium sp. 12/1 on neutralization of alkaline wastewater. 2012 ScientificWorldJournal pmid:22666107
Hubert HB et al. Olfactory sensitivity in humans: genetic versus environmental control. 1980 Science pmid:7189296
Xiong M et al. A bio-catalytic approach to aliphatic ketones. 2012 Sci Rep pmid:22416247
Mendes V et al. Mycobacterium tuberculosis Rv2419c, the missing glucosyl-3-phosphoglycerate phosphatase for the second step in methylglucose lipopolysaccharide biosynthesis. 2011 Sci Rep pmid:22355692
Tjellström B et al. Gut microflora associated characteristics in first-degree relatives of children with celiac disease. 2007 Scand. J. Gastroenterol. pmid:17852880
Jakobsdottir G et al. Fasting serum concentration of short-chain fatty acids in subjects with microscopic colitis and celiac disease: no difference compared with controls, but between genders. 2013 Scand. J. Gastroenterol. pmid:23600961
Cittadini E and Catalano G [Use of a new combination: dihydroxyprogesterone acetophenide and estradiol-3-benzoate-17 isobutyrate in gynecology]. 1973-1974 Riv Ostet Ginecol Prat Med Perinat pmid:4620236
Watkins JB and Klaassen CD Choleretic effect of structural analogs of valproic acid in the rat. 1983 Res. Commun. Chem. Pathol. Pharmacol. pmid:6407071
Ghanadian M et al. New tigliane-type diterpenoids from Euphorbia aellenii Rech. f. with immunomodulatory activity. 2011 Res Pharm Sci pmid:22049276
Sathishkumar K et al. Prenatal testosterone-induced fetal growth restriction is associated with down-regulation of rat placental amino acid transport. 2011 Reprod. Biol. Endocrinol. pmid:21812961
Fushinobu S et al. Crystal structures of a meta-cleavage product hydrolase from Pseudomonas fluorescens IP01 (CumD) complexed with cleavage products. 2002 Protein Sci. pmid:12192074
Xiong Y et al. Short-chain fatty acids stimulate leptin production in adipocytes through the G protein-coupled receptor GPR41. 2004 Proc. Natl. Acad. Sci. U.S.A. pmid:14722361
Zhang WF et al. Effects of isomalto-oligosaccharides on broiler performance and intestinal microflora. 2003 Poult. Sci. pmid:12710488
Dunkley KD et al. Comparison of in vitro fermentation and molecular microbial profiles of high-fiber feed substrates incubated with chicken cecal inocula. 2007 Poult. Sci. pmid:17435012
Lam KK et al. Nitazoxanide stimulates autophagy and inhibits mTORC1 signaling and intracellular proliferation of Mycobacterium tuberculosis. 2012 PLoS Pathog. pmid:22589723
Conde-Álvarez R et al. The lipopolysaccharide core of Brucella abortus acts as a shield against innate immunity recognition. 2012 PLoS Pathog. pmid:22589715
Kanistanon D et al. A Francisella mutant in lipid A carbohydrate modification elicits protective immunity. 2008 PLoS Pathog. pmid:18266468
Dalmasso G et al. Butyrate transcriptionally enhances peptide transporter PepT1 expression and activity. 2008 PLoS ONE pmid:18575574
Can Güven S and Laska M Olfactory sensitivity and odor structure-activity relationships for aliphatic carboxylic acids in CD-1 mice. 2012 PLoS ONE pmid:22479594
Kaur D et al. Initiation of methylglucose lipopolysaccharide biosynthesis in mycobacteria. 2009 PLoS ONE pmid:19421329
Si J et al. Activation of NF-κB in basolateral amygdala is required for memory reconsolidation in auditory fear conditioning. 2012 PLoS ONE pmid:22957038
Bruant G et al. Genomic analysis of carbon monoxide utilization and butanol production by Clostridium carboxidivorans strain P7. 2010 PLoS ONE pmid:20885952
Hao GF and Yang GF The role of Phe82 and Phe351 in auxin-induced substrate perception by TIR1 ubiquitin ligase: a novel insight from molecular dynamics simulations. 2010 PLoS ONE pmid:20505777
March C et al. Dissection of host cell signal transduction during Acinetobacter baumannii-triggered inflammatory response. 2010 PLoS ONE pmid:20383325
Kwak J et al. Genetically-based olfactory signatures persist despite dietary variation. 2008 PLoS ONE pmid:18974891
Hartmann K et al. Fast homeostatic plasticity of inhibition via activity-dependent vesicular filling. 2008 PLoS ONE pmid:18714334