ISOBUTYRIC ACID

ISOBUTYRIC ACID is a lipid of Fatty Acyls (FA) class. Isobutyric acid is associated with abnormalities such as Atrophy, Muscular, Spinobulbar. The involved functions are known as Signal Transduction, Oxidation, Vmax, Metabolic Inhibition and Regulation. Isobutyric acid often locates in Cytoplasm, Plasma membrane, peroxisome, Mouse Embryonic Fibroblast and Protoplasm. The associated genes with ISOBUTYRIC ACID are Candidate Disease Gene, CDKN1A gene, MYC gene, E2F1 gene and HBP1 gene. The related lipids are butyrate, Butyrates, lipid structure, Fatty Acids and Propionate. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of ISOBUTYRIC ACID, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with ISOBUTYRIC ACID?

ISOBUTYRIC ACID is suspected in Atrophy, Muscular, Spinobulbar and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with ISOBUTYRIC ACID

MeSH term MeSH ID Detail
Body Weight D001835 333 associated lipids
Adenocarcinoma D000230 166 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Stomach Ulcer D013276 75 associated lipids
Hyperlipidemias D006949 73 associated lipids
Gastrointestinal Hemorrhage D006471 27 associated lipids
Malabsorption Syndromes D008286 16 associated lipids
Werner Syndrome D014898 4 associated lipids
Myoclonic Epilepsies, Progressive D020191 3 associated lipids
Total 10

PubChem Associated disorders and diseases

What pathways are associated with ISOBUTYRIC ACID

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with ISOBUTYRIC ACID?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with ISOBUTYRIC ACID?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with ISOBUTYRIC ACID?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with ISOBUTYRIC ACID?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with ISOBUTYRIC ACID?

Knock-out

Knock-out are used in the study 'G1/S arrest induced by histone deacetylase inhibitor sodium butyrate in E1A + Ras-transformed cells is mediated through down-regulation of E2F activity and stabilization of beta-catenin.' (Abramova MV et al., 2006).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with ISOBUTYRIC ACID

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Authors Title Published Journal PubMed Link
Hu ZH and Yu HQ Anaerobic digestion of cattail by rumen cultures. 2006 Waste Manag pmid:16198552
Waligora-Dupriet AJ et al. Evidence for clostridial implication in necrotizing enterocolitis through bacterial fermentation in a gnotobiotic quail model. 2005 Pediatr. Res. pmid:16189185
Sercu B et al. Degradation of isobutanal at high loading rates in a compost biofilter. 2005 J Air Waste Manag Assoc pmid:16187591
Talasz H et al. Histone H4-lysine 20 monomethylation is increased in promoter and coding regions of active genes and correlates with hyperacetylation. 2005 J. Biol. Chem. pmid:16166085
Wang Y et al. Exploration of the direct metabolic effects of mercury II chloride on the kidney of Sprague-Dawley rats using high-resolution magic angle spinning 1H NMR spectroscopy of intact tissue and pattern recognition. 2006 J Pharm Biomed Anal pmid:16146678
Bachetti T et al. An in vitro approach to test the possible role of candidate factors in the transcriptional regulation of the RET proto-oncogene. 2005 Gene Expr. pmid:16127999
Vellutini M et al. Beta-cyclolavandulyl and beta-isocyclolavandulyl esters from Peucedanum paniculatum L., an endemic species to Corsica. 2005 Phytochemistry pmid:16099484
Okawa K et al. Degradation of chemical substances using wet peroxide oxidation under mild conditions. 2005 J. Hazard. Mater. pmid:16081206
Vyalikh A et al. Evidence of microphase separation in controlled pore glasses. 2005 Solid State Nucl Magn Reson pmid:16061359
Schemmel S et al. Local structure of a phase-separating binary mixture in a mesoporous glass matrix studied by small-angle neutron scattering. 2005 J Chem Phys pmid:16035804