ISOBUTYRIC ACID

ISOBUTYRIC ACID is a lipid of Fatty Acyls (FA) class. Isobutyric acid is associated with abnormalities such as Atrophy, Muscular, Spinobulbar. The involved functions are known as Signal Transduction, Oxidation, Vmax, Metabolic Inhibition and Regulation. Isobutyric acid often locates in Cytoplasm, Plasma membrane, peroxisome, Mouse Embryonic Fibroblast and Protoplasm. The associated genes with ISOBUTYRIC ACID are Candidate Disease Gene, CDKN1A gene, MYC gene, E2F1 gene and HBP1 gene. The related lipids are butyrate, Butyrates, lipid structure, Fatty Acids and Propionate. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of ISOBUTYRIC ACID, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with ISOBUTYRIC ACID?

ISOBUTYRIC ACID is suspected in Atrophy, Muscular, Spinobulbar and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with ISOBUTYRIC ACID

MeSH term MeSH ID Detail
Adenocarcinoma D000230 166 associated lipids
Body Weight D001835 333 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Gastrointestinal Hemorrhage D006471 27 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Hyperlipidemias D006949 73 associated lipids
Malabsorption Syndromes D008286 16 associated lipids
Stomach Ulcer D013276 75 associated lipids
Werner Syndrome D014898 4 associated lipids
Myoclonic Epilepsies, Progressive D020191 3 associated lipids
Total 10

PubChem Associated disorders and diseases

What pathways are associated with ISOBUTYRIC ACID

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with ISOBUTYRIC ACID?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with ISOBUTYRIC ACID?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with ISOBUTYRIC ACID?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with ISOBUTYRIC ACID?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with ISOBUTYRIC ACID?

Knock-out

Knock-out are used in the study 'G1/S arrest induced by histone deacetylase inhibitor sodium butyrate in E1A + Ras-transformed cells is mediated through down-regulation of E2F activity and stabilization of beta-catenin.' (Abramova MV et al., 2006).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with ISOBUTYRIC ACID

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Authors Title Published Journal PubMed Link
Frenkel C and Haard NF Initiation of Ripening in Bartlett Pear with an Antiauxin alpha(p-Chlorophenoxy)isobutyric Acid. 1973 Plant Physiol. pmid:16658566
Marrè MT et al. Stimulation of Weak Acid Uptake and Increase in Cell Sap pH as Evidence for Fusicoccin- and K-Induced Cytosol Alkalinization. 1986 Plant Physiol. pmid:16665014
Jaison PG et al. Direct determination of lanthanides in simulated irradiated thoria fuels using reversed-phase high-performance liquid chromatography. 2006 J Chromatogr A pmid:16687151
Wrigley DM Inhibition of Clostridium perfringens sporulation by Bacteroides fragilis and short-chain fatty acids. 2004 Anaerobe pmid:16701530
Abramova MV et al. G1/S arrest induced by histone deacetylase inhibitor sodium butyrate in E1A + Ras-transformed cells is mediated through down-regulation of E2F activity and stabilization of beta-catenin. 2006 J. Biol. Chem. pmid:16717102
Dresler K et al. Production of a recombinant polyester-cleaving hydrolase from Thermobifida fusca in Escherichia coli. 2006 Bioprocess Biosyst Eng pmid:16770590
Fahrbach M et al. Denitratisoma oestradiolicum gen. nov., sp. nov., a 17beta-oestradiol-degrading, denitrifying betaproteobacterium. 2006 Int. J. Syst. Evol. Microbiol. pmid:16825628
Kim YW and Baird JK Reaction kinetics and critical phenomena: rates of some first order gas evolution reactions in binary solvents with a consolute point. 2005 J Phys Chem A pmid:16833817
Kim YW and Baird JK Chemical equilibrium and critical phenomena: the solubilities of manganese dioxide and aluminum oxide in isobutyric acid + water near its consolute point. 2005 J Phys Chem B pmid:16853203
Reed JJ et al. Effects of season and inclusion of corn distillers dried grains with solubles in creep feed on intake, microbial protein synthesis and efficiency, ruminal fermentation, digestion, and performance of nursing calves grazing native range in southeastern North Dakota. 2006 J. Anim. Sci. pmid:16864882