ISOBUTYRIC ACID

ISOBUTYRIC ACID is a lipid of Fatty Acyls (FA) class. Isobutyric acid is associated with abnormalities such as Atrophy, Muscular, Spinobulbar. The involved functions are known as Signal Transduction, Oxidation, Vmax, Metabolic Inhibition and Regulation. Isobutyric acid often locates in Cytoplasm, Plasma membrane, peroxisome, Mouse Embryonic Fibroblast and Protoplasm. The associated genes with ISOBUTYRIC ACID are Candidate Disease Gene, CDKN1A gene, MYC gene, E2F1 gene and HBP1 gene. The related lipids are butyrate, Butyrates, lipid structure, Fatty Acids and Propionate. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of ISOBUTYRIC ACID, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with ISOBUTYRIC ACID?

ISOBUTYRIC ACID is suspected in Atrophy, Muscular, Spinobulbar and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with ISOBUTYRIC ACID

MeSH term MeSH ID Detail
Adenocarcinoma D000230 166 associated lipids
Body Weight D001835 333 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Gastrointestinal Hemorrhage D006471 27 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Hyperlipidemias D006949 73 associated lipids
Malabsorption Syndromes D008286 16 associated lipids
Stomach Ulcer D013276 75 associated lipids
Werner Syndrome D014898 4 associated lipids
Myoclonic Epilepsies, Progressive D020191 3 associated lipids
Total 10

PubChem Associated disorders and diseases

What pathways are associated with ISOBUTYRIC ACID

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with ISOBUTYRIC ACID?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with ISOBUTYRIC ACID?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with ISOBUTYRIC ACID?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with ISOBUTYRIC ACID?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with ISOBUTYRIC ACID?

Knock-out

Knock-out are used in the study 'G1/S arrest induced by histone deacetylase inhibitor sodium butyrate in E1A + Ras-transformed cells is mediated through down-regulation of E2F activity and stabilization of beta-catenin.' (Abramova MV et al., 2006).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with ISOBUTYRIC ACID

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Authors Title Published Journal PubMed Link
Huys G et al. Aeromonas hydrophila subsp. ranae subsp. nov., isolated from septicaemic farmed frogs in Thailand. 2003 Int. J. Syst. Evol. Microbiol. pmid:12807217
Gabler MT and Heinrichs AJ Altering soluble and potentially rumen degradable protein for prepubertal Holstein heifers. 2003 J. Dairy Sci. pmid:12836949
Noftsger SM et al. Effects of 2-hydroxy-4-(methylthio) butanoic acid (HMB) on microbial growth in continuous culture. 2003 J. Dairy Sci. pmid:12939087
Batstone DJ et al. Kinetics of thermophilic, anaerobic oxidation of straight and branched chain butyrate and valerate. 2003 Biotechnol. Bioeng. pmid:12966576
Shigematsu T et al. Delftia tsuruhatensis sp. nov., a terephthalate-assimilating bacterium isolated from activated sludge. 2003 Int. J. Syst. Evol. Microbiol. pmid:13130036
Grenier D Nutritional interactions between two suspected periodontopathogens, Treponema denticola and Porphyromonas gingivalis. 1992 Infect. Immun. pmid:1333450
Wang SS et al. Cleavage and deprotection of peptides on MBHA-resin with hydrogen bromide. 1992 Sep-Oct Int. J. Pept. Protein Res. pmid:1335998
WEGNER GH and FOSTER EM Incorporation of isobutyrate and valerate into cellular plasmalogen by Bacteroides succinogenes. 1963 J. Bacteriol. pmid:13999496
SOCRANSKY SS et al. DEPENDENCY OF TREPONEMA MICRODENTIUM ON OTHER ORAL ORGANISMS FOR ISOBUTYRATE, POLYAMINES, AND A CONTROLLED OXIDATION-REDUCTION POTENTIAL. 1964 J. Bacteriol. pmid:14197888
Lemoff AS et al. Binding energies of water to sodiated valine and structural isomers in the gas phase: the effect of proton affinity on zwitterion stability. 2003 J. Am. Chem. Soc. pmid:14583055