ISOBUTYRIC ACID

ISOBUTYRIC ACID is a lipid of Fatty Acyls (FA) class. Isobutyric acid is associated with abnormalities such as Atrophy, Muscular, Spinobulbar. The involved functions are known as Signal Transduction, Oxidation, Vmax, Metabolic Inhibition and Regulation. Isobutyric acid often locates in Cytoplasm, Plasma membrane, peroxisome, Mouse Embryonic Fibroblast and Protoplasm. The associated genes with ISOBUTYRIC ACID are Candidate Disease Gene, CDKN1A gene, MYC gene, E2F1 gene and HBP1 gene. The related lipids are butyrate, Butyrates, lipid structure, Fatty Acids and Propionate. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of ISOBUTYRIC ACID, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with ISOBUTYRIC ACID?

ISOBUTYRIC ACID is suspected in Atrophy, Muscular, Spinobulbar and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with ISOBUTYRIC ACID

MeSH term MeSH ID Detail
Stomach Ulcer D013276 75 associated lipids
Adenocarcinoma D000230 166 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Body Weight D001835 333 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Hyperlipidemias D006949 73 associated lipids
Malabsorption Syndromes D008286 16 associated lipids
Gastrointestinal Hemorrhage D006471 27 associated lipids
Werner Syndrome D014898 4 associated lipids
Myoclonic Epilepsies, Progressive D020191 3 associated lipids
Total 10

PubChem Associated disorders and diseases

What pathways are associated with ISOBUTYRIC ACID

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with ISOBUTYRIC ACID?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with ISOBUTYRIC ACID?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with ISOBUTYRIC ACID?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with ISOBUTYRIC ACID?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with ISOBUTYRIC ACID?

Knock-out

Knock-out are used in the study 'G1/S arrest induced by histone deacetylase inhibitor sodium butyrate in E1A + Ras-transformed cells is mediated through down-regulation of E2F activity and stabilization of beta-catenin.' (Abramova MV et al., 2006).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

NCBI Entrez Crosslinks

All references with ISOBUTYRIC ACID

Download all related citations
Per page 10 20 50 100 | Total 515
Authors Title Published Journal PubMed Link
pmid:
Durand T et al. Role of intracellular buffering power on the mitochondria-cytosol pH gradient in the rat liver perfused at 4 degrees C. 1999 Cryobiology pmid:10079131
Huang H et al. Carboxypeptidase A3 (CPA3): a novel gene highly induced by histone deacetylase inhibitors during differentiation of prostate epithelial cancer cells. 1999 Cancer Res. pmid:10383164
Sullivan HM and Martin SA Effects of a Saccharomyces cerevisiae culture on in vitro mixed ruminal microorganism fermentation. 1999 J. Dairy Sci. pmid:10509261
Plaga W et al. Modification of Cys-418 of pyruvate formate-lyase by methacrylic acid, based on its radical mechanism. 2000 FEBS Lett. pmid:10648809
Le Maire V et al. System A neutral amino acid transporter regulation by interleukin-1beta in human osteoarthritic synovial cells: evidence for involvement of prostaglandin E(2) as a second messenger. 2000 J. Cell. Physiol. pmid:10699967
Seigler DS and Lampman RL Isobutyric acid from the Brindley's glands of Triatoma lecticularia. 2000 J. Am. Mosq. Control Assoc. pmid:10757489
Sekiguchi Y et al. Syntrophothermus lipocalidus gen. nov., sp. nov., a novel thermophilic, syntrophic, fatty-acid-oxidizing anaerobe which utilizes isobutyrate. 2000 Int. J. Syst. Evol. Microbiol. pmid:10758888
Kristensen NB et al. Net portal appearance of volatile fatty acids in sheep intraruminally infused with mixtures of acetate, propionate, isobutyrate, butyrate, and valerate. 2000 J. Anim. Sci. pmid:10834594
Kambara T and Tomioka K Controlling factors in chiral bisoxazoline-catalyzed asymmetric lithium ester enolate-imine condensation producing a beta-lactam. 2000 Chem. Pharm. Bull. pmid:11045472
Takahashi N and Yamada T Pathways for amino acid metabolism by Prevotella intermedia and Prevotella nigrescens. 2000 Oral Microbiol. Immunol. pmid:11155172
Guerenstein PG and Guerin PM Olfactory and behavioural responses of the blood-sucking bug Triatoma infestans to odours of vertebrate hosts. 2001 J. Exp. Biol. pmid:11171309
Bandyk CA et al. Effect of ruminal vs postruminal administration of degradable protein on utilization of low-quality forage by beef steers. 2001 J. Anim. Sci. pmid:11204704
Zaharia V et al. Effects of short chain fatty acids on colonic Na+ absorption and enzyme activity. 2001 Comp. Biochem. Physiol., Part A Mol. Integr. Physiol. pmid:11223395
Itoh N et al. Cloning and biochemical characterization of Co(2+)-activated bromoperoxidase-esterase (perhydrolase) from Pseudomonas putida IF-3 strain. 2001 Biochim. Biophys. Acta pmid:11342031
Hung MW et al. Differential regulation of placental and germ cell alkaline phosphatases by glucocorticoid and sodium butyrate in human gastric carcinoma cell line TMK-1. 2001 Arch. Biochem. Biophys. pmid:11361139
Etchebehere C et al. Comamonas nitrativorans sp. nov., a novel denitrifier isolated from a denitrifying reactor treating landfill leachate. 2001 Int. J. Syst. Evol. Microbiol. pmid:11411724
Takahashi N and Sato T Preferential utilization of dipeptides by Porphyromonas gingivalis. 2001 J. Dent. Res. pmid:11437213
Besong S et al. Influence of supplemental chromium on concentrations of liver triglyceride, blood metabolites and rumen VFA profile in steers fed a moderately high fat diet. 2001 J. Dairy Sci. pmid:11467818
Fujino T et al. Molecular identification and characterization of two medium-chain acyl-CoA synthetases, MACS1 and the Sa gene product. 2001 J. Biol. Chem. pmid:11470804
Osborne A et al. Histone deacetylase activity represses gamma interferon-inducible HLA-DR gene expression following the establishment of a DNase I-hypersensitive chromatin conformation. 2001 Mol. Cell. Biol. pmid:11533238
Yu HQ and Fang HH Acidification of mid- and high-strength dairy wastewaters. 2001 Water Res. pmid:11561632
McGuinness MC et al. Evaluation of pharmacological induction of fatty acid beta-oxidation in X-linked adrenoleukodystrophy. 2001 Sep-Oct Mol. Genet. Metab. pmid:11592822
Suresh CH et al. Revisiting Markovnikov addition to alkenes via molecular electrostatic potential. 2001 J. Org. Chem. pmid:11597205
Walczak RJ et al. Nonactin biosynthesis: disruption of the polyketide synthase genes, nonKJ, in Streptomyces griseus leads to an overall 96 decrease in macrotetrolide production, yet a net increase in nonactin analogues which incorporate isobutyrate. 2001 J. Am. Chem. Soc. pmid:11604004
Yamada M et al. New thiocholine ester substrates for the assay of human serum cholinesterase. 2001 Clin. Chem. pmid:11673363
Smirnova N and Reynolds KA Branched-chain fatty acid biosynthesis in Escherichia coli. 2001 J. Ind. Microbiol. Biotechnol. pmid:11687938
Duray SJ et al. Comparison of chemical analysis of residual monomer in a chemical-cured dental acrylic material to an FTIR method. 1997 Dent Mater pmid:11696903
Fang HH and Yu H Mesophilic acidification of gelatinaceous wastewater. 2002 J. Biotechnol. pmid:11738717
Paulukat J et al. Expression and release of IL-18 binding protein in response to IFN-gamma. 2001 J. Immunol. pmid:11739524
Kukushkin AN et al. Downregulation of c-fos gene transcription in cells transformed by E1A and cHa-ras oncogenes: a role of sustained activation of MAP/ERK kinase cascade and of inactive chromatin structure at c-fos promoter. 2002 Oncogene pmid:11850800
Kim NS and Lee GM Inhibition of sodium butyrate-induced apoptosis in recombinant Chinese hamster ovary cells by constitutively expressing antisense RNA of caspase-3. 2002 Biotechnol. Bioeng. pmid:11870612
Rojas JC et al. A reinvestigation of brindley's gland exocrine compounds of Rhodnius prolixus (Hemiptera: Reduviidae). 2002 J. Med. Entomol. pmid:11931024
Forsee WT and Elbein AD Glycoprotein biosynthesis in plants. Demonstration of lipid-linked oligosaccharides of mannose and N-acetylglucosamine. 1975 J. Biol. Chem. pmid:1194283
Hernández-Orte P et al. Relationship between varietal amino acid profile of grapes and wine aromatic composition. Experiments with model solutions and chemometric study. 2002 J. Agric. Food Chem. pmid:11982416
Akay V et al. NutriDense and waxy corn hybrids: effects on site and extent of disappearance of nutrients in sheep. 2002 J. Anim. Sci. pmid:12019623
Yang CM Response of forage fiber degradation by ruminal microorganisms to branched-chain volatile fatty acids, amino acids, and dipeptides. 2002 J. Dairy Sci. pmid:12086054
Mata R et al. Sesquiterpene lactones and phenylpropanoids from Cosmos pringlei. 2002 J. Nat. Prod. pmid:12141867
Cibis E et al. Biodegradation of potato slops from a rural distillery by thermophilic aerobic bacteria. 2002 Bioresour. Technol. pmid:12146644
Hernandez-Eugenio G et al. Sporanaerobacter acetigenes gen. nov., sp. nov., a novel acetogenic, facultatively sulfur-reducing bacterium. 2002 Int. J. Syst. Evol. Microbiol. pmid:12148631
Hansen JL et al. The structures of four macrolide antibiotics bound to the large ribosomal subunit. 2002 Mol. Cell pmid:12150912
Kumazawa S et al. Studies of the constituents of Uruguayan propolis. 2002 J. Agric. Food Chem. pmid:12166959
Fushinobu S et al. Crystal structures of a meta-cleavage product hydrolase from Pseudomonas fluorescens IP01 (CumD) complexed with cleavage products. 2002 Protein Sci. pmid:12192074
Suzuki-Mizushima Y et al. Enhancement of NGF- and cholera toxin-induced neurite outgrowth by butyrate in PC12 cells. 2002 Brain Res. pmid:12270499
Hernández-Eugenio G et al. Clostridium thiosulfatireducens sp. nov., a proteolytic, thiosulfate- and sulfur-reducing bacterium isolated from an upflow anaerobic sludge blanket (UASB) reactor. 2002 Int. J. Syst. Evol. Microbiol. pmid:12361247
Andreani F et al. New alpha-substituted arylthioacetic derivatives forming analogues of clofibrate. 1975 Farmaco Sci pmid:1236653
Ith M et al. Observation and identification of metabolites emerging during postmortem decomposition of brain tissue by means of in situ 1H-magnetic resonance spectroscopy. 2002 Magn Reson Med pmid:12418008
Yu HQ and Fang HH Acidogenesis of gelatin-rich wastewater in an upflow anaerobic reactor: influence of pH and temperature. 2003 Water Res. pmid:12465788
Brown AJ et al. The Orphan G protein-coupled receptors GPR41 and GPR43 are activated by propionate and other short chain carboxylic acids. 2003 J. Biol. Chem. pmid:12496283
Gallert C et al. Scale-up of anaerobic digestion of the biowaste fraction from domestic wastes. 2003 Water Res. pmid:12598207