ISOBUTYRIC ACID

ISOBUTYRIC ACID is a lipid of Fatty Acyls (FA) class. Isobutyric acid is associated with abnormalities such as Atrophy, Muscular, Spinobulbar. The involved functions are known as Signal Transduction, Oxidation, Vmax, Metabolic Inhibition and Regulation. Isobutyric acid often locates in Cytoplasm, Plasma membrane, peroxisome, Mouse Embryonic Fibroblast and Protoplasm. The associated genes with ISOBUTYRIC ACID are Candidate Disease Gene, CDKN1A gene, MYC gene, E2F1 gene and HBP1 gene. The related lipids are butyrate, Butyrates, lipid structure, Fatty Acids and Propionate. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of ISOBUTYRIC ACID, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with ISOBUTYRIC ACID?

ISOBUTYRIC ACID is suspected in Atrophy, Muscular, Spinobulbar and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with ISOBUTYRIC ACID

MeSH term MeSH ID Detail
Stomach Ulcer D013276 75 associated lipids
Adenocarcinoma D000230 166 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Body Weight D001835 333 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Hyperlipidemias D006949 73 associated lipids
Malabsorption Syndromes D008286 16 associated lipids
Gastrointestinal Hemorrhage D006471 27 associated lipids
Werner Syndrome D014898 4 associated lipids
Myoclonic Epilepsies, Progressive D020191 3 associated lipids
Total 10

PubChem Associated disorders and diseases

What pathways are associated with ISOBUTYRIC ACID

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with ISOBUTYRIC ACID?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with ISOBUTYRIC ACID?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with ISOBUTYRIC ACID?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with ISOBUTYRIC ACID?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with ISOBUTYRIC ACID?

Knock-out

Knock-out are used in the study 'G1/S arrest induced by histone deacetylase inhibitor sodium butyrate in E1A + Ras-transformed cells is mediated through down-regulation of E2F activity and stabilization of beta-catenin.' (Abramova MV et al., 2006).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with ISOBUTYRIC ACID

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Authors Title Published Journal PubMed Link
Zhilina TN et al. ["Candidatus contubernalis alkalaceticum," an obligately syntrophic alkaliphilic bacterium capable of anaerobic acetate oxidation in a coculture with Desulfonatronum cooperativum]. 2005 Nov-Dec Mikrobiologiia pmid:16400991
Charrier C et al. A novel class of CoA-transferase involved in short-chain fatty acid metabolism in butyrate-producing human colonic bacteria. 2006 Microbiology (Reading, Engl.) pmid:16385128
Zhu K et al. Precursor and temperature modulation of fatty acid composition and growth of Listeria monocytogenes cold-sensitive mutants with transposon-interrupted branched-chain alpha-keto acid dehydrogenase. 2005 Microbiology (Reading, Engl.) pmid:15699210
Strobel GA et al. Muscodor albus E-6, an endophyte of Guazuma ulmifolia making volatile antibiotics: isolation, characterization and experimental establishment in the host plant. 2007 Microbiology (Reading, Engl.) pmid:17660425
Narihiro T et al. Comparative Genomics of Syntrophic Branched-Chain Fatty Acid Degrading Bacteria. 2016 Microbes Environ. pmid:27431485
Glissman K et al. Methanogenic pathway and archaeal community structure in the sediment of eutrophic Lake Dagow: effect of temperature. 2004 Microb. Ecol. pmid:15692859
Schaible GA et al. Characterization of an Endophytic Gloeosporium sp. and Its Novel Bioactivity with "Synergistans". 2015 Microb. Ecol. pmid:25501886
Taurino C et al. Actinoplanes teichomyceticus ATCC 31121 as a cell factory for producing teicoplanin. 2011 Microb. Cell Fact. pmid:22008254
Lang K et al. Metabolic engineering of Pseudomonas sp. strain VLB120 as platform biocatalyst for the production of isobutyric acid and other secondary metabolites. 2014 Microb. Cell Fact. pmid:24397404
Pscheidt B and Glieder A Yeast cell factories for fine chemical and API production. 2008 Microb. Cell Fact. pmid:18684335