ISOBUTYRIC ACID

ISOBUTYRIC ACID is a lipid of Fatty Acyls (FA) class. Isobutyric acid is associated with abnormalities such as Atrophy, Muscular, Spinobulbar. The involved functions are known as Signal Transduction, Oxidation, Vmax, Metabolic Inhibition and Regulation. Isobutyric acid often locates in Cytoplasm, Plasma membrane, peroxisome, Mouse Embryonic Fibroblast and Protoplasm. The associated genes with ISOBUTYRIC ACID are Candidate Disease Gene, CDKN1A gene, MYC gene, E2F1 gene and HBP1 gene. The related lipids are butyrate, Butyrates, lipid structure, Fatty Acids and Propionate. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of ISOBUTYRIC ACID, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with ISOBUTYRIC ACID?

ISOBUTYRIC ACID is suspected in Atrophy, Muscular, Spinobulbar and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with ISOBUTYRIC ACID

MeSH term MeSH ID Detail
Stomach Ulcer D013276 75 associated lipids
Adenocarcinoma D000230 166 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Body Weight D001835 333 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Hyperlipidemias D006949 73 associated lipids
Malabsorption Syndromes D008286 16 associated lipids
Gastrointestinal Hemorrhage D006471 27 associated lipids
Werner Syndrome D014898 4 associated lipids
Myoclonic Epilepsies, Progressive D020191 3 associated lipids
Total 10

PubChem Associated disorders and diseases

What pathways are associated with ISOBUTYRIC ACID

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with ISOBUTYRIC ACID?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with ISOBUTYRIC ACID?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with ISOBUTYRIC ACID?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with ISOBUTYRIC ACID?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with ISOBUTYRIC ACID?

Knock-out

Knock-out are used in the study 'G1/S arrest induced by histone deacetylase inhibitor sodium butyrate in E1A + Ras-transformed cells is mediated through down-regulation of E2F activity and stabilization of beta-catenin.' (Abramova MV et al., 2006).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with ISOBUTYRIC ACID

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Authors Title Published Journal PubMed Link
Apps PJ et al. Aggregation pheromones of the bont tick Amblyomma hebraeum: identification of candidates for bioassay. 1988 Onderstepoort J. Vet. Res. pmid:3194113
Kikugawa M et al. Bisfunction of propionic acid on purified rat liver beta-ureidopropionase. 1988 FEBS Lett. pmid:3345846
Miyano M et al. (Acyloxy)benzophenones and (acyloxy)-4-pyrones. A new class of inhibitors of human neutrophil elastase. 1988 J. Med. Chem. pmid:3361575
Tanner RS and Wolfe RS Nutritional requirements of Methanomicrobium mobile. 1988 Appl. Environ. Microbiol. pmid:3377488
Matsuzaki K et al. Inhibition of cortical collecting tubule chloride transport by organic acids. 1988 J. Clin. Invest. pmid:3392216
Aiello RJ and Armentano LE Effects of volatile fatty acids on propionate metabolism and gluconeogenesis in caprine hepatocytes. 1987 J. Dairy Sci. pmid:3448105
Hornung DE et al. Olfactory mucosa/air partitioning of odorants. 1987 Brain Res. pmid:3496142
Maroni BJ et al. System A amino acid transport in incubated muscle: effects of insulin and acute uremia. 1986 Am. J. Physiol. pmid:3524266
Maroni BJ et al. System ASC and sodium-independent neutral amino acid transport in muscle of uremic rats. 1986 Am. J. Physiol. pmid:3524267
Sugahara K et al. Insulin stimulates amino acid transport by alveolar type II epithelial cells in primary culture. 1987 Am. Rev. Respir. Dis. pmid:3548506
Schofield CJ Demonstration of isobutyric acid in some triatomine bugs. 1979 Acta Trop. pmid:35929
Rasoamananjara D et al. Characterization of Flavobacterium species by analysis of volatile fatty acid production. 1986 J. Gen. Microbiol. pmid:3625166
Blake JD et al. Determination of organic acids in sugar cane process juice by high-performance liquid chromatography: improved resolution using dual Aminex HPX-87H cation-exchange columns equilibrated to different temperatures. 1987 J. Chromatogr. pmid:3654841
DiAngelo CR and Heath AG Comparison of in vivo energy metabolism in the brain of rainbow trout, Salmo gairdneri and bullhead catfish, Ictalurus nebulosus during anoxia. 1987 Comp. Biochem. Physiol., B pmid:3677607
Pena F et al. The effect of heat treatment of whole cottonseed on site and extent of protein digestion in dairy cows. 1986 J. Anim. Sci. pmid:3755130
Sherman MM et al. Biosynthesis of lasalocid A. Metabolic interrelationships of carboxylic acid precursors and polyether antibiotics. 1986 J. Antibiot. pmid:3759663
Boerner P and Saier MH Hormonal regulation of the System A amino acid transport adaptive response mechanism in a kidney epithelial cell line (MDCK). 1985 J. Cell. Physiol. pmid:3881463
Lundquist RG et al. Influence of methionine hydroxy analog and DL-methionine on rumen protozoa and volatile fatty acids. 1985 J. Dairy Sci. pmid:3935701
Boerner P and Saier MH Adaptive regulatory control of System A transport activity in a kidney epithelial cell line (MDCK) and in a transformed variant (MDCK-T1). 1985 J. Cell. Physiol. pmid:3968188
Manning NJ and Pollitt RJ Tracer studies of the interconversion of R- and S-methylmalonic semialdehydes in man. 1985 Biochem. J. pmid:4062908