ISOBUTYRIC ACID

ISOBUTYRIC ACID is a lipid of Fatty Acyls (FA) class. Isobutyric acid is associated with abnormalities such as Atrophy, Muscular, Spinobulbar. The involved functions are known as Signal Transduction, Oxidation, Vmax, Metabolic Inhibition and Regulation. Isobutyric acid often locates in Cytoplasm, Plasma membrane, peroxisome, Mouse Embryonic Fibroblast and Protoplasm. The associated genes with ISOBUTYRIC ACID are Candidate Disease Gene, CDKN1A gene, MYC gene, E2F1 gene and HBP1 gene. The related lipids are butyrate, Butyrates, lipid structure, Fatty Acids and Propionate. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of ISOBUTYRIC ACID, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with ISOBUTYRIC ACID?

ISOBUTYRIC ACID is suspected in Atrophy, Muscular, Spinobulbar and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with ISOBUTYRIC ACID

MeSH term MeSH ID Detail
Stomach Ulcer D013276 75 associated lipids
Adenocarcinoma D000230 166 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Body Weight D001835 333 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Hyperlipidemias D006949 73 associated lipids
Malabsorption Syndromes D008286 16 associated lipids
Gastrointestinal Hemorrhage D006471 27 associated lipids
Werner Syndrome D014898 4 associated lipids
Myoclonic Epilepsies, Progressive D020191 3 associated lipids
Total 10

PubChem Associated disorders and diseases

What pathways are associated with ISOBUTYRIC ACID

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with ISOBUTYRIC ACID?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with ISOBUTYRIC ACID?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with ISOBUTYRIC ACID?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with ISOBUTYRIC ACID?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with ISOBUTYRIC ACID?

Knock-out

Knock-out are used in the study 'G1/S arrest induced by histone deacetylase inhibitor sodium butyrate in E1A + Ras-transformed cells is mediated through down-regulation of E2F activity and stabilization of beta-catenin.' (Abramova MV et al., 2006).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with ISOBUTYRIC ACID

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Authors Title Published Journal PubMed Link
Dickschat JS et al. Biosynthesis of iso-fatty acids in myxobacteria. 2005 Org. Biomol. Chem. pmid:16032360
Okawa K et al. Degradation of chemical substances using wet peroxide oxidation under mild conditions. 2005 J. Hazard. Mater. pmid:16081206
Stojakowska A et al. Antimicrobial activity of 10-isobutyryloxy-8,9-epoxythymol isobutyrate. 2005 Fitoterapia pmid:16242268
Kim YW and Baird JK Chemical equilibrium and critical phenomena: the solubilities of manganese dioxide and aluminum oxide in isobutyric acid + water near its consolute point. 2005 J Phys Chem B pmid:16853203
Kim YW and Baird JK Reaction kinetics and critical phenomena: rates of some first order gas evolution reactions in binary solvents with a consolute point. 2005 J Phys Chem A pmid:16833817
Vyalikh A et al. Evidence of microphase separation in controlled pore glasses. 2005 Solid State Nucl Magn Reson pmid:16061359
Schemmel S et al. Local structure of a phase-separating binary mixture in a mesoporous glass matrix studied by small-angle neutron scattering. 2005 J Chem Phys pmid:16035804
Trotta M et al. Solid lipid micro-particles carrying insulin formed by solvent-in-water emulsion-diffusion technique. 2005 Int J Pharm pmid:15620868
Wakabayashi K et al. Gene expression associated with the decrease in malignant phenotype of human liver cancer cells following stimulation with a histone deacetylase inhibitor. 2005 Int. J. Oncol. pmid:15586245
Vellutini M et al. Beta-cyclolavandulyl and beta-isocyclolavandulyl esters from Peucedanum paniculatum L., an endemic species to Corsica. 2005 Phytochemistry pmid:16099484
Kuroda J et al. Promotion of cell differentiation, and suppression of cell growth and cyclooxygenase-2 expression by differentiation-inducing agents in human oral squamous carcinoma SCC25 cells. 2005 Int. J. Oncol. pmid:15645120
Looby E et al. Bile acid deoxycholate induces differential subcellular localisation of the PKC isoenzymes beta 1, epsilon and delta in colonic epithelial cells in a sodium butyrate insensitive manner. 2005 Int. J. Cancer pmid:15645414
Hiesberger T et al. Role of the hepatocyte nuclear factor-1beta (HNF-1beta) C-terminal domain in Pkhd1 (ARPKD) gene transcription and renal cystogenesis. 2005 J. Biol. Chem. pmid:15647252
Sercu B et al. Degradation of isobutanal at high loading rates in a compost biofilter. 2005 J Air Waste Manag Assoc pmid:16187591
Sakurazawa T and Ohkusa T Cytotoxicity of organic acids produced by anaerobic intestinal bacteria on cultured epithelial cells. 2005 J. Gastroenterol. pmid:16007394
Stokrová J et al. Response of HT115, a highly invasive human colorectal adenocarcinoma cell line, to sodium butyrate treatment and glucose deprivation. 2005 Int. J. Oncol. pmid:15703838
El Hamidi A et al. Microextraction of bacterial lipid A: easy and rapid method for mass spectrometric characterization. 2005 J. Lipid Res. pmid:15930524
Izawa H et al. Effects of p21cip1/waf1 overexpression on growth, apoptosis and differentiation in human colon carcinoma cells. 2005 Int. J. Oncol. pmid:15942645
Waligora-Dupriet AJ et al. Evidence for clostridial implication in necrotizing enterocolitis through bacterial fermentation in a gnotobiotic quail model. 2005 Pediatr. Res. pmid:16189185
Bachetti T et al. An in vitro approach to test the possible role of candidate factors in the transcriptional regulation of the RET proto-oncogene. 2005 Gene Expr. pmid:16127999
Miller SJ et al. Short-chain fatty acids modulate gene expression for vascular endothelial cell adhesion molecules. 2005 Nutrition pmid:15925300
Wu S et al. Characteristic volatiles from young and aged fruiting bodies of wild Polyporus sulfureus (Bull.:Fr.) Fr. 2005 J. Agric. Food Chem. pmid:15913320
Sullivan HM et al. Ruminal fermentation and amino acid flow in Holstein steers fed whole cottonseed with elevated concentrations of free fatty acids in the oil. 2005 J. Dairy Sci. pmid:15653536
Zhilina TN et al. ["Candidatus contubernalis alkalaceticum," an obligately syntrophic alkaliphilic bacterium capable of anaerobic acetate oxidation in a coculture with Desulfonatronum cooperativum]. 2005 Nov-Dec Mikrobiologiia pmid:16400991
Zhao G et al. Rapid determination of short-chain fatty acids in colonic contents and faeces of humans and rats by acidified water-extraction and direct-injection gas chromatography. 2006 Biomed. Chromatogr. pmid:16206138
Clifford S et al. Monte carlo simulation of carboxylic acid phase equilibria. 2006 J Phys Chem B pmid:17064162
Hu ZH and Yu HQ Anaerobic digestion of cattail by rumen cultures. 2006 Waste Manag pmid:16198552
Hu ZH et al. Application of response surface methodology for optimization of acidogenesis of cattail by rumen cultures. 2006 Bioresour. Technol. pmid:16289873
Fahrbach M et al. Denitratisoma oestradiolicum gen. nov., sp. nov., a 17beta-oestradiol-degrading, denitrifying betaproteobacterium. 2006 Int. J. Syst. Evol. Microbiol. pmid:16825628
Guo J et al. An efficient synthesis of a potent PPARpan agonist. 2006 J. Org. Chem. pmid:17025332
Charrier C et al. A novel class of CoA-transferase involved in short-chain fatty acid metabolism in butyrate-producing human colonic bacteria. 2006 Microbiology (Reading, Engl.) pmid:16385128
Castellanos P et al. Conformational change of poly(ethylene glycol) near the critical point of isobutyric acid + water. 2006 J Phys Chem B pmid:17078654
Ballivet-Tkatchenko D et al. Insertion reaction of carbon dioxide into Sn-OR bond. Synthesis, structure and DFT calculations of di- and tetranuclear isopropylcarbonato tin(IV) complexes. 2006 Dalton Trans pmid:17077890
Panagou EZ and Tassou CC Changes in volatile compounds and related biochemical profile during controlled fermentation of cv. Conservolea green olives. 2006 Food Microbiol. pmid:16943076
Venkatesu P Polymer modifies the critical region of the coexisting liquid phases. 2006 J Phys Chem B pmid:16942068
Manrique G et al. Chemical communication in Chagas disease vectors. Source, identity, and potential function of volatiles released by the metasternal and Brindley's glands of Triatoma infestans adults. 2006 J. Chem. Ecol. pmid:16902820
Li L et al. Nucleophilic group transfer reactivity for fibric acid derived drug molecules. 2006 J Pharm Sci pmid:16865691
de Souza MD et al. Characterization of cachaça and rum aroma. 2006 J. Agric. Food Chem. pmid:16417309
Wang Y et al. Exploration of the direct metabolic effects of mercury II chloride on the kidney of Sprague-Dawley rats using high-resolution magic angle spinning 1H NMR spectroscopy of intact tissue and pattern recognition. 2006 J Pharm Biomed Anal pmid:16146678
Seeling K et al. On the effects of Fusarium toxin contaminated wheat and wheat chaff on nutrient utilisation and turnover of deoxynivalenol and zearalenone in vitro (Rusitec). 2006 Toxicol In Vitro pmid:16321500
Mu Y et al. The role of pH in the fermentative H2 production from an acidogenic granule-based reactor. 2006 Chemosphere pmid:16466779
Ying M et al. Sodium butyrate ameliorates histone hypoacetylation and neurodegenerative phenotypes in a mouse model for DRPLA. 2006 J. Biol. Chem. pmid:16407196
Pojman JA et al. Evidence for the existence of an effective interfacial tension between miscible fluids: isobutyric acid-water and 1-butanol-water in a spinning-drop tensiometer. 2006 Langmuir pmid:16519456
Masaki Y et al. Recyclable polymeric pi-acid catalyst effective on Mannich-type reaction in water. 2006 Chem. Pharm. Bull. pmid:16595974
Abramova MV et al. G1/S arrest induced by histone deacetylase inhibitor sodium butyrate in E1A + Ras-transformed cells is mediated through down-regulation of E2F activity and stabilization of beta-catenin. 2006 J. Biol. Chem. pmid:16717102
Jaison PG et al. Direct determination of lanthanides in simulated irradiated thoria fuels using reversed-phase high-performance liquid chromatography. 2006 J Chromatogr A pmid:16687151
Kendall MM et al. Butyrate- and propionate-degrading syntrophs from permanently cold marine sediments in Skan Bay, Alaska, and description of Algorimarina butyrica gen. nov., sp. nov. 2006 FEMS Microbiol. Lett. pmid:16907746
Reed JJ et al. Effects of season and inclusion of corn distillers dried grains with solubles in creep feed on intake, microbial protein synthesis and efficiency, ruminal fermentation, digestion, and performance of nursing calves grazing native range in southeastern North Dakota. 2006 J. Anim. Sci. pmid:16864882
Dresler K et al. Production of a recombinant polyester-cleaving hydrolase from Thermobifida fusca in Escherichia coli. 2006 Bioprocess Biosyst Eng pmid:16770590
Bertin L et al. Performances and microbial features of an aerobic packed-bed biofilm reactor developed to post-treat an olive mill effluent from an anaerobic GAC reactor. 2006 Microb. Cell Fact. pmid:16595023