ISOBUTYRIC ACID

ISOBUTYRIC ACID is a lipid of Fatty Acyls (FA) class. Isobutyric acid is associated with abnormalities such as Atrophy, Muscular, Spinobulbar. The involved functions are known as Signal Transduction, Oxidation, Vmax, Metabolic Inhibition and Regulation. Isobutyric acid often locates in Cytoplasm, Plasma membrane, peroxisome, Mouse Embryonic Fibroblast and Protoplasm. The associated genes with ISOBUTYRIC ACID are Candidate Disease Gene, CDKN1A gene, MYC gene, E2F1 gene and HBP1 gene. The related lipids are butyrate, Butyrates, lipid structure, Fatty Acids and Propionate. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of ISOBUTYRIC ACID, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with ISOBUTYRIC ACID?

ISOBUTYRIC ACID is suspected in Atrophy, Muscular, Spinobulbar and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with ISOBUTYRIC ACID

MeSH term MeSH ID Detail
Stomach Ulcer D013276 75 associated lipids
Adenocarcinoma D000230 166 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Body Weight D001835 333 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Hyperlipidemias D006949 73 associated lipids
Malabsorption Syndromes D008286 16 associated lipids
Gastrointestinal Hemorrhage D006471 27 associated lipids
Werner Syndrome D014898 4 associated lipids
Myoclonic Epilepsies, Progressive D020191 3 associated lipids
Total 10

PubChem Associated disorders and diseases

What pathways are associated with ISOBUTYRIC ACID

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with ISOBUTYRIC ACID?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with ISOBUTYRIC ACID?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with ISOBUTYRIC ACID?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with ISOBUTYRIC ACID?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with ISOBUTYRIC ACID?

Knock-out

Knock-out are used in the study 'G1/S arrest induced by histone deacetylase inhibitor sodium butyrate in E1A + Ras-transformed cells is mediated through down-regulation of E2F activity and stabilization of beta-catenin.' (Abramova MV et al., 2006).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with ISOBUTYRIC ACID

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Authors Title Published Journal PubMed Link
Prakash S et al. Gut microbiota: next frontier in understanding human health and development of biotherapeutics. 2011 Biologics pmid:21847343
Sathishkumar K et al. Prenatal testosterone-induced fetal growth restriction is associated with down-regulation of rat placental amino acid transport. 2011 Reprod. Biol. Endocrinol. pmid:21812961
Lever MA Acetogenesis in the energy-starved deep biosphere - a paradox? 2011 Front Microbiol pmid:22347874
Picard A and Ferdelman TG Linking microbial heterotrophic activity and sediment lithology in oxic, oligotrophic sub-seafloor sediments of the north atlantic ocean. 2011 Front Microbiol pmid:22207869
Houston MA et al. Stable differences in intrinsic mitochondrial membrane potential of tumor cell subpopulations reflect phenotypic heterogeneity. 2011 Int J Cell Biol pmid:21760799
Sentürk E et al. Treatment efficiency and VFA composition of a thermophilic anaerobic contact reactor treating food industry wastewater. 2010 J. Hazard. Mater. pmid:20022175
Rohwerder T and Müller RH Biosynthesis of 2-hydroxyisobutyric acid (2-HIBA) from renewable carbon. 2010 Microb. Cell Fact. pmid:20184738
Zhang K et al. Proteiniclasticum ruminis gen. nov., sp. nov., a strictly anaerobic proteolytic bacterium isolated from yak rumen. 2010 Int. J. Syst. Evol. Microbiol. pmid:19915115
Kotal A et al. Ultrasound-induced in situ formation of coordination organogels from isobutyric acids and zinc oxide nanoparticles. 2010 Langmuir pmid:20020763
Rezanka T et al. Pilot-plant cultivation of Streptomyces griseus producing homologues of nonactin by precursor-directed biosynthesis and their identification by LC/MS-ESI. 2010 J. Antibiot. pmid:20664602
Sato H and Shiogama Y Acetone and isopropanol in ruminal fluid and feces of lactating dairy cows. 2010 J. Vet. Med. Sci. pmid:19959888
Thrash JC et al. Description of the novel perchlorate-reducing bacteria Dechlorobacter hydrogenophilus gen. nov., sp. nov.and Propionivibrio militaris, sp. nov. 2010 Appl. Microbiol. Biotechnol. pmid:19921177
Sorokin DY et al. Propionate and butyrate dependent bacterial sulfate reduction at extremely haloalkaline conditions and description of Desulfobotulus alkaliphilus sp. nov. 2010 Extremophiles pmid:19888546
Brambilla E et al. Complete genome sequence of Methanoplanus petrolearius type strain (SEBR 4847). 2010 Stand Genomic Sci pmid:21304750
Benus RF et al. Impact of digestive and oropharyngeal decontamination on the intestinal microbiota in ICU patients. 2010 Intensive Care Med pmid:20232045
Schilmiller A et al. Mass spectrometry screening reveals widespread diversity in trichome specialized metabolites of tomato chromosomal substitution lines. 2010 Plant J. pmid:20113441
Parker DB et al. Recovery of agricultural odors and odorous compounds from polyvinyl fluoride film bags. 2010 Sensors (Basel) pmid:22163671
Urriola PE and Stein HH Effects of distillers dried grains with solubles on amino acid, energy, and fiber digestibility and on hindgut fermentation of dietary fiber in a corn-soybean meal diet fed to growing pigs. 2010 J. Anim. Sci. pmid:20023135
Schellenberger S et al. Metabolic responses of novel cellulolytic and saccharolytic agricultural soil Bacteria to oxygen. 2010 Environ. Microbiol. pmid:20050868
Freguia S et al. Microbial fuel cells operating on mixed fatty acids. 2010 Bioresour. Technol. pmid:19854639