ISOBUTYRIC ACID

ISOBUTYRIC ACID is a lipid of Fatty Acyls (FA) class. Isobutyric acid is associated with abnormalities such as Atrophy, Muscular, Spinobulbar. The involved functions are known as Signal Transduction, Oxidation, Vmax, Metabolic Inhibition and Regulation. Isobutyric acid often locates in Cytoplasm, Plasma membrane, peroxisome, Mouse Embryonic Fibroblast and Protoplasm. The associated genes with ISOBUTYRIC ACID are Candidate Disease Gene, CDKN1A gene, MYC gene, E2F1 gene and HBP1 gene. The related lipids are butyrate, Butyrates, lipid structure, Fatty Acids and Propionate. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of ISOBUTYRIC ACID, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with ISOBUTYRIC ACID?

ISOBUTYRIC ACID is suspected in Atrophy, Muscular, Spinobulbar and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with ISOBUTYRIC ACID

MeSH term MeSH ID Detail
Stomach Ulcer D013276 75 associated lipids
Adenocarcinoma D000230 166 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Body Weight D001835 333 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Hyperlipidemias D006949 73 associated lipids
Malabsorption Syndromes D008286 16 associated lipids
Gastrointestinal Hemorrhage D006471 27 associated lipids
Werner Syndrome D014898 4 associated lipids
Myoclonic Epilepsies, Progressive D020191 3 associated lipids
Total 10

PubChem Associated disorders and diseases

What pathways are associated with ISOBUTYRIC ACID

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with ISOBUTYRIC ACID?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with ISOBUTYRIC ACID?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with ISOBUTYRIC ACID?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with ISOBUTYRIC ACID?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with ISOBUTYRIC ACID?

Knock-out

Knock-out are used in the study 'G1/S arrest induced by histone deacetylase inhibitor sodium butyrate in E1A + Ras-transformed cells is mediated through down-regulation of E2F activity and stabilization of beta-catenin.' (Abramova MV et al., 2006).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

NCBI Entrez Crosslinks

All references with ISOBUTYRIC ACID

Download all related citations
Per page 10 20 50 100 | Total 515
Authors Title Published Journal PubMed Link
Suzuki-Mizushima Y et al. Enhancement of NGF- and cholera toxin-induced neurite outgrowth by butyrate in PC12 cells. 2002 Brain Res. pmid:12270499
Rojas JC et al. A reinvestigation of brindley's gland exocrine compounds of Rhodnius prolixus (Hemiptera: Reduviidae). 2002 J. Med. Entomol. pmid:11931024
Yang CM Response of forage fiber degradation by ruminal microorganisms to branched-chain volatile fatty acids, amino acids, and dipeptides. 2002 J. Dairy Sci. pmid:12086054
Kumazawa S et al. Studies of the constituents of Uruguayan propolis. 2002 J. Agric. Food Chem. pmid:12166959
Hernandez-Eugenio G et al. Sporanaerobacter acetigenes gen. nov., sp. nov., a novel acetogenic, facultatively sulfur-reducing bacterium. 2002 Int. J. Syst. Evol. Microbiol. pmid:12148631
Hernández-Eugenio G et al. Clostridium thiosulfatireducens sp. nov., a proteolytic, thiosulfate- and sulfur-reducing bacterium isolated from an upflow anaerobic sludge blanket (UASB) reactor. 2002 Int. J. Syst. Evol. Microbiol. pmid:12361247
Bernard JK et al. Ruminal fermentation and bacterial protein synthesis of whole cottonseed coated with combinations of gelatinized corn starch and urea. 2003 J. Dairy Sci. pmid:14672196
Shigematsu T et al. Delftia tsuruhatensis sp. nov., a terephthalate-assimilating bacterium isolated from activated sludge. 2003 Int. J. Syst. Evol. Microbiol. pmid:13130036
Zhang WF et al. Effects of isomalto-oligosaccharides on broiler performance and intestinal microflora. 2003 Poult. Sci. pmid:12710488
Noftsger SM et al. Effects of 2-hydroxy-4-(methylthio) butanoic acid (HMB) on microbial growth in continuous culture. 2003 J. Dairy Sci. pmid:12939087
Batstone DJ et al. Kinetics of thermophilic, anaerobic oxidation of straight and branched chain butyrate and valerate. 2003 Biotechnol. Bioeng. pmid:12966576
Pind PF et al. Dynamics of the anaerobic process: effects of volatile fatty acids. 2003 Biotechnol. Bioeng. pmid:12701145
Huys G et al. Aeromonas hydrophila subsp. ranae subsp. nov., isolated from septicaemic farmed frogs in Thailand. 2003 Int. J. Syst. Evol. Microbiol. pmid:12807217
Cao X et al. Aberrant regulation of human intestinal proglucagon gene expression in the NCI-H716 cell line. 2003 Endocrinology pmid:12697711
Matich AJ et al. Actinidia arguta: volatile compounds in fruit and flowers. 2003 Phytochemistry pmid:12737978
Diao J et al. Crystallization of butyrate kinase 2 from Thermotoga maritima mediated by vapor diffusion of acetic acid. 2003 Acta Crystallogr. D Biol. Crystallogr. pmid:12777787
Gabler MT and Heinrichs AJ Altering soluble and potentially rumen degradable protein for prepubertal Holstein heifers. 2003 J. Dairy Sci. pmid:12836949
Schauber J et al. Expression of the cathelicidin LL-37 is modulated by short chain fatty acids in colonocytes: relevance of signalling pathways. 2003 Gut pmid:12692061
Le Poul E et al. Functional characterization of human receptors for short chain fatty acids and their role in polymorphonuclear cell activation. 2003 J. Biol. Chem. pmid:12711604
Brown AJ et al. The Orphan G protein-coupled receptors GPR41 and GPR43 are activated by propionate and other short chain carboxylic acids. 2003 J. Biol. Chem. pmid:12496283