(r)-3-hydroxybutanoic acid

(r)-3-hydroxybutanoic acid is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 2725 references associated with (r)-3-hydroxybutanoic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for (r)-3-hydroxybutanoic acid

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with (r)-3-hydroxybutanoic acid

MeSH term MeSH ID Detail
Congenital Hyperinsulinism D044903 1 associated lipids
Spinal Muscular Atrophies of Childhood D014897 1 associated lipids
Status Epilepticus D013226 1 associated lipids
Pancreatitis, Chronic D050500 1 associated lipids
Aortopulmonary Septal Defect D001028 1 associated lipids
Septo-Optic Dysplasia D025962 1 associated lipids
Lipoma D008067 1 associated lipids
Azotemia D053099 1 associated lipids
Fructose-1,6-Diphosphatase Deficiency D015319 1 associated lipids
Lethargy D053609 1 associated lipids
Forearm Injuries D005543 1 associated lipids
Median Neuropathy D020423 1 associated lipids
Heredodegenerative Disorders, Nervous System D020271 1 associated lipids
Ulnar Neuropathies D020424 1 associated lipids
Adenocarcinoma, Clear Cell D018262 1 associated lipids
Lacrimal Apparatus Diseases D007766 1 associated lipids
Pallor D010167 1 associated lipids
Basal Ganglia Cerebrovascular Disease D020144 1 associated lipids
Wrist Injuries D014954 1 associated lipids
Heart Septal Defects D006343 2 associated lipids
Sandhoff Disease D012497 2 associated lipids
Epilepsy, Generalized D004829 2 associated lipids
Kearns-Sayre Syndrome D007625 2 associated lipids
Intracranial Hemorrhages D020300 2 associated lipids
Cardiac Output, Low D002303 2 associated lipids
Cysticercosis D003551 2 associated lipids
Glycogen Storage Disease Type III D006010 2 associated lipids
Multiple Endocrine Neoplasia Type 1 D018761 2 associated lipids
Insulin Coma D007331 2 associated lipids
Encephalopathy, Bovine Spongiform D016643 2 associated lipids
Short Bowel Syndrome D012778 3 associated lipids
Mastitis D008413 3 associated lipids
Exostoses, Multiple Hereditary D005097 3 associated lipids
Dystocia D004420 3 associated lipids
Placenta, Retained D018457 3 associated lipids
Thyrotoxicosis D013971 3 associated lipids
Dwarfism, Pituitary D004393 3 associated lipids
Alkalosis D000471 3 associated lipids
Lipid Metabolism Disorders D052439 3 associated lipids
Acid-Base Imbalance D000137 3 associated lipids
Fetal Macrosomia D005320 3 associated lipids
HIV Wasting Syndrome D019247 3 associated lipids
Pyruvate Dehydrogenase Complex Deficiency Disease D015325 3 associated lipids
Spasms, Infantile D013036 3 associated lipids
Hepatitis, Chronic D006521 3 associated lipids
Bulimia D002032 3 associated lipids
Fascioliasis D005211 3 associated lipids
Pyruvate Metabolism, Inborn Errors D015323 3 associated lipids
Hepatitis, Viral, Human D006525 3 associated lipids
Alkalosis, Respiratory D000472 4 associated lipids
Jaundice D007565 4 associated lipids
Glycogen Storage Disease Type I D005953 4 associated lipids
Gastroenteritis D005759 4 associated lipids
Syndrome D013577 4 associated lipids
Parvoviridae Infections D010322 4 associated lipids
Wounds, Nonpenetrating D014949 4 associated lipids
Hyperglycemic Hyperosmolar Nonketotic Coma D006944 4 associated lipids
Muscle Rigidity D009127 4 associated lipids
Puerperal Disorders D011644 4 associated lipids
Glycogen Storage Disease D006008 4 associated lipids
Neural Tube Defects D009436 5 associated lipids
Abortion, Veterinary D000034 5 associated lipids
Asphyxia D001237 5 associated lipids
Hyperandrogenism D017588 5 associated lipids
Hyponatremia D007010 5 associated lipids
Vibrio Infections D014735 5 associated lipids
Trypanosomiasis, African D014353 5 associated lipids
Epilepsy, Reflex D020195 5 associated lipids
Liver Failure D017093 5 associated lipids
Hepatitis, Alcoholic D006519 5 associated lipids
Plant Poisoning D010939 5 associated lipids
Sleep Deprivation D012892 5 associated lipids
Uterine Diseases D014591 6 associated lipids
Malnutrition D044342 6 associated lipids
Endometritis D004716 6 associated lipids
Placental Insufficiency D010927 6 associated lipids
Intestinal Diseases D007410 6 associated lipids
Fetal Alcohol Spectrum Disorders D063647 6 associated lipids
Acromegaly D000172 6 associated lipids
Stomach Diseases D013272 7 associated lipids
Lipidoses D008064 7 associated lipids
Trichostrongyloidiasis D014252 7 associated lipids
Hypopituitarism D007018 7 associated lipids
Genomic Instability D042822 7 associated lipids
Trematode Infections D014201 8 associated lipids
Anorexia D000855 8 associated lipids
Irritable Bowel Syndrome D043183 8 associated lipids
Mastitis, Bovine D008414 8 associated lipids
Obesity, Morbid D009767 8 associated lipids
Diabetes, Gestational D016640 8 associated lipids
Infant, Newborn, Diseases D007232 9 associated lipids
Hyperlipidemia, Familial Combined D006950 9 associated lipids
Foreign-Body Reaction D005549 10 associated lipids
Neoplasms, Experimental D009374 10 associated lipids
Fatigue D005221 10 associated lipids
Glycosuria D006029 10 associated lipids
Lung Diseases, Obstructive D008173 10 associated lipids
Sheep Diseases D012757 10 associated lipids
Dehydration D003681 11 associated lipids
Thinness D013851 11 associated lipids
Per page 10 20 50 100 | Total 185

PubChem Associated disorders and diseases

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with (r)-3-hydroxybutanoic acid

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Per page 10 20 50 100 | Total 2707
Authors Title Published Journal PubMed Link
Seifi HA et al. Metabolic predictors of post-partum disease and culling risk in dairy cattle. 2011 Vet. J. pmid:20457532
Brunner MP et al. Effect of heparin administration on metabolomic profiles in samples obtained during cardiac catheterization. 2011 Circ Cardiovasc Genet pmid:22010138
Moazzami AA et al. Nuclear magnetic resonance-based metabolomics enable detection of the effects of a whole grain rye and rye bran diet on the metabolic profile of plasma in prostate cancer patients. 2011 J. Nutr. pmid:22013201
Chapinal N et al. The association of serum metabolites with clinical disease during the transition period. 2011 J. Dairy Sci. pmid:21943741
Kreipe L et al. First report about the mode of action of combined butafosfan and cyanocobalamin on hepatic metabolism in nonketotic early lactating cows. 2011 J. Dairy Sci. pmid:21943742
Samala R et al. The ketogenic diet changes metabolite levels in hippocampal extracellular fluid. 2011 Neurochem. Int. pmid:21070829
Lu J et al. Closing the anion gap: contribution of D-lactate to diabetic ketoacidosis. 2011 Clin. Chim. Acta pmid:21036159
Schutz PW et al. Effects of d-3-hydroxybutyrate treatment on hypoglycemic coma in rat pups. 2011 Exp. Neurol. pmid:21056562
Tanaka K et al. Cell growth and P(3HB) accumulation from CO2 of a carbon monoxide-tolerant hydrogen-oxidizing bacterium, Ideonella sp. O-1. 2011 Appl. Microbiol. Biotechnol. pmid:21695533
Meier H et al. [Ethanol, sugar, acid and coma]. 2011 Praxis (Bern 1994) pmid:21698566
Numis AL et al. The relationship of ketosis and growth to the efficacy of the ketogenic diet in infantile spasms. 2011 Epilepsy Res. pmid:21700429
Liu F et al. Metabolic engineering of Aeromonas hydrophila 4AK4 for production of copolymers of 3-hydroxybutyrate and medium-chain-length 3-hydroxyalkanoate. 2011 Bioresour. Technol. pmid:21680176
Li XB et al. Renal function of dairy cows with subclinical ketosis. 2011 Vet. Rec. pmid:21672951
Deng-Bryant Y et al. Ketogenic diet prevents alterations in brain metabolism in young but not adult rats after traumatic brain injury. 2011 J. Neurotrauma pmid:21635175
Ruprechter G et al. Metabolic and endocrine profiles and reproductive parameters in dairy cows under grazing conditions: effect of polymorphisms in somatotropic axis genes. 2011 Acta Vet. Scand. pmid:21635772
Langley-Evans SC et al. Protein restriction in the pregnant mouse modifies fetal growth and pulmonary development: role of fetal exposure to {beta}-hydroxybutyrate. 2011 Exp. Physiol. pmid:20851857
Arora S et al. Diagnostic accuracy of point-of-care testing for diabetic ketoacidosis at emergency-department triage: {beta}-hydroxybutyrate versus the urine dipstick. 2011 Diabetes Care pmid:21307381
Iwata K et al. Central injection of ketone body suppresses luteinizing hormone release via the catecholaminergic pathway in female rats. 2011 J. Reprod. Dev. pmid:21358145
Sun AK et al. [Fabrication of larynx-shape tissue engineered cartilage by means of filling together with wrapping with pedicle myofascial flap]. 2011 Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi pmid:22336014
McArt JA et al. A field trial on the effect of propylene glycol on milk yield and resolution of ketosis in fresh cows diagnosed with subclinical ketosis. 2011 J. Dairy Sci. pmid:22118089
Bényei B et al. Plasma progesterone, metabolic hormones and beta-hydroxybutyrate in Holstein-Friesian cows after superovulation. 2011 Acta Vet. Hung. pmid:22079709
Dutton SB et al. Protective effect of the ketogenic diet in Scn1a mutant mice. 2011 Epilepsia pmid:21801172
Hsu WY et al. Enantioselective determination of 3-hydroxybutyrate in the tissues of normal and streptozotocin-induced diabetic rats of different ages. 2011 J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. pmid:21856256
Dabos KJ et al. Regional variations in the concentrations of ketone bodies in cirrhosis and hepatic encephalopathy: a study in patients with TIPSS. 2011 Liver Int. pmid:21457443
Valayannopoulos V et al. Successful treatment of severe cardiomyopathy in glycogen storage disease type III With D,L-3-hydroxybutyrate, ketogenic and high-protein diet. 2011 Pediatr. Res. pmid:21857385
Ruskin DN et al. A ketogenic diet delays weight loss and does not impair working memory or motor function in the R6/2 1J mouse model of Huntington's disease. 2011 Physiol. Behav. pmid:21501628
Eloqayli H et al. [2,4-(13)C]β-hydroxybutyrate metabolism in astrocytes and C6 glioblastoma cells. 2011 Neurochem. Res. pmid:21538079
OuYang D et al. Metabolomic profiling of serum from human pancreatic cancer patients using 1H NMR spectroscopy and principal component analysis. 2011 Appl. Biochem. Biotechnol. pmid:21505807
Ugwu CU et al. Production of (R)-3-hydroxybutyric acid by fermentation and bioconversion processes with Azohydromonas lata. 2011 Bioresour. Technol. pmid:21507620
Sevastianova K et al. Genetic variation in PNPLA3 (adiponutrin) confers sensitivity to weight loss-induced decrease in liver fat in humans. 2011 Am. J. Clin. Nutr. pmid:21525193
Krogh MA et al. Latent class evaluation of a milk test, a urine test, and the fat-to-protein percentage ratio in milk to diagnose ketosis in dairy cows. 2011 J. Dairy Sci. pmid:21524525
Zebeli Q et al. Perturbations of plasma metabolites correlated with the rise of rumen endotoxin in dairy cows fed diets rich in easily degradable carbohydrates. 2011 J. Dairy Sci. pmid:21524527
Norouzian MA et al. Rumen development and growth of Balouchi lambs offered alfalfa hay pre- and post-weaning. 2011 Trop Anim Health Prod pmid:21465104
Minlebaev M and Khazipov R Antiepileptic effects of endogenous beta-hydroxybutyrate in suckling infant rats. 2011 Epilepsy Res. pmid:21470827
Valergakis GE et al. Phenotypic association between energy balance indicators and reproductive performance in primiparous Holstein cows. 2011 Vet. Rec. pmid:21493532
Chmiel-Perzyńska I et al. Novel aspect of ketone action: β-hydroxybutyrate increases brain synthesis of kynurenic acid in vitro. 2011 Neurotox Res pmid:20838951
Tisi DK et al. Fetal exposure to altered amniotic fluid glucose, insulin, and insulin-like growth factor-binding protein 1 occurs before screening for gestational diabetes mellitus. 2011 Diabetes Care pmid:20855548
Jankovec Z et al. Influence of physical activity on metabolic state within a 3-h interruption of continuous subcutaneous insulin infusion in patients with type 1 diabetes. 2011 Diabetes Technol. Ther. pmid:21877927
Kılıçay E et al. Preparation and characterization of poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) (PHBHHX) based nanoparticles for targeted cancer therapy. 2011 Eur J Pharm Sci pmid:21884788
Wang Y et al. MicroRNAs in the regulation of interfacial behaviors of MSCs cultured on microgrooved surface pattern. 2011 Biomaterials pmid:21890196
González FD et al. Relationship among blood indicators of lipomobilization and hepatic function during early lactation in high-yielding dairy cows. 2011 J. Vet. Sci. pmid:21897097
Lim S et al. D-β-hydroxybutyrate is protective in mouse models of Huntington's disease. 2011 PLoS ONE pmid:21931779
Zhou C et al. How useful is basal renal tubular epithelial cell vacuolization as a marker for significant hyperglycemia at autopsy? 2011 J. Forensic Sci. pmid:21827461
Stojanovic V and Ihle S Role of beta-hydroxybutyric acid in diabetic ketoacidosis: a review. 2011 Can. Vet. J. pmid:21731100
Tyzio R et al. Depolarizing actions of GABA in immature neurons depend neither on ketone bodies nor on pyruvate. 2011 J. Neurosci. pmid:21209187
Pifferi F et al. Mild experimental ketosis increases brain uptake of 11C-acetoacetate and 18F-fluorodeoxyglucose: a dual-tracer PET imaging study in rats. 2011 Nutr Neurosci pmid:21605500
Hart KJ et al. Effect of whole-crop pea (Pisum sativum L.) silages differing in condensed tannin content as a substitute for grass silage and soybean meal on the performance, metabolism, and carcass characteristics of lambs. 2011 J. Anim. Sci. pmid:21571892
Jackson RA et al. Energy metabolites in pre- and postpartum dairy cattle as predictors of reproductive disorders. 2011 Vet. Rec. pmid:21546407
Albano N et al. Plasma metabolite levels predict bird growth rates: A field test of model predictive ability. 2011 Comp. Biochem. Physiol., Part A Mol. Integr. Physiol. pmid:21575739
Bielohuby M et al. Induction of ketosis in rats fed low-carbohydrate, high-fat diets depends on the relative abundance of dietary fat and protein. 2011 Am. J. Physiol. Endocrinol. Metab. pmid:20943751