(r)-3-hydroxybutanoic acid

(r)-3-hydroxybutanoic acid is a lipid of Fatty Acyls (FA) class.

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There are no associated biomedical information in the current reference collection.

Current reference collection contains 2725 references associated with (r)-3-hydroxybutanoic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for (r)-3-hydroxybutanoic acid

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with (r)-3-hydroxybutanoic acid

MeSH term MeSH ID Detail
Congenital Abnormalities D000013 11 associated lipids
Abortion, Spontaneous D000022 12 associated lipids
Abortion, Veterinary D000034 5 associated lipids
Acid-Base Imbalance D000137 3 associated lipids
Acidosis D000138 13 associated lipids
Acromegaly D000172 6 associated lipids
Adenocarcinoma D000230 166 associated lipids
Albuminuria D000419 18 associated lipids
Alcoholic Intoxication D000435 15 associated lipids
Alkalosis D000471 3 associated lipids
Alkalosis, Respiratory D000472 4 associated lipids
Alzheimer Disease D000544 76 associated lipids
Amyotrophic Lateral Sclerosis D000690 11 associated lipids
Anorexia D000855 8 associated lipids
Hypoxia D000860 23 associated lipids
Aortopulmonary Septal Defect D001028 1 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Asphyxia D001237 5 associated lipids
Birth Weight D001724 23 associated lipids
Body Weight D001835 333 associated lipids
Per page 10 20 50 100 | Total 185

PubChem Associated disorders and diseases

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with (r)-3-hydroxybutanoic acid

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Authors Title Published Journal PubMed Link
Flachowsky G et al. [The influence of oral niacin doses during different dietary protein levels on indexes of rumen fermentation, blood parameters and fattening performance of young bulls]. 1993 Arch Tierernahr pmid:7487473
Gomez L and Jouany JP Effects of lasalocid and cationomycin on the evolution of certain parameters in the blood plasma of sheep. 1994 Arch Tierernahr pmid:7619003
Windisch W and Kirchgessner M [Concentrations of metabolites and hormones in the blood plasma of lactating dairy cows during treatment with recombinant bovine somatotropin (BST)]. 1992 Arch Tierernahr pmid:1296558
Hallebeek JM and Beynen AC The concentration of plasma triacylglycerols in horses fed diets containing either medium chain triacylglycerols or an isoenergetic amount of starch or cellulose. 2001 Arch Tierernahr pmid:12068482
González-Manchón C et al. Role of endogenous fatty acids in the control of hepatic gluconeogenesis. 1992 Arch. Biochem. Biophys. pmid:1727653
Lincoln BC et al. Metabolism of S-3-hydroxybutyrate in the perfused rat liver. 1987 Arch. Biochem. Biophys. pmid:3688882
Reed WD and Ozand PT Enzymes of L-(+)-3-hydroxybutyrate metabolism in the rat. 1980 Arch. Biochem. Biophys. pmid:7447486
Patel TB et al. The regulation of the pyruvate dehydrogenase complex in the perfused rat liver: a role for the mitochondrial monocarboxylate translocator. 1982 Arch. Biochem. Biophys. pmid:6803675
Carmona A and Freedland RA Effect of glycerol and dihydroxyacetone on hepatic lipogenesis. 1989 Arch. Biochem. Biophys. pmid:2712570
Ikeda T et al. Effect of beta-hydroxybutyrate and acetoacetate on insulin and glucagon secretion from perfused rat pancreas. 1987 Arch. Biochem. Biophys. pmid:3307630
Malaisse WJ et al. Metabolism of alpha-D-[1,2-13C]glucose pentaacetate and alpha-D-glucose penta[2-13C]acetate in rat hepatocytes. 2000 Arch. Biochem. Biophys. pmid:11019820
Toth PP et al. Respiratory control and ADP:O coupling ratios of isolated chick heart mitochondria. 1990 Arch. Biochem. Biophys. pmid:2153362
Rodríguez-Enríquez S et al. Substrate oxidation and ATP supply in AS-30D hepatoma cells. 2000 Arch. Biochem. Biophys. pmid:10683245
Nagy LE and Kretchmer N Effect of diabetic ketosis on jejunal glutaminase. 1986 Arch. Biochem. Biophys. pmid:3089169
Gibson R et al. Effects of diabetes on the activity and content of the branched-chain alpha-ketoacid dehydrogenase complex in liver. 1993 Arch. Biochem. Biophys. pmid:8215407
Scofield RF et al. On the lack of formation of L-(+)-3-hydroxybutyrate by liver. 1982 Arch. Biochem. Biophys. pmid:7082002
Morris AA et al. Evaluation of fasts for investigating hypoglycaemia or suspected metabolic disease. 1996 Arch. Dis. Child. pmid:8869190
Hassan AA et al. Changes of some serum parameters and amino acids content in rats after chronic sublethal doses of dimethoate. 1994 Arch. Environ. Contam. Toxicol. pmid:8060171
Roca P et al. Metabolic response to short term starvation in non-pregnant and late pregnant cafeteria-obese rats. 1989 Arch. Int. Physiol. Biochim. pmid:2475087
Huguet J et al. Alterations of energy metabolism induced by hexadecane in mice. 1989 Arch. Int. Physiol. Biochim. pmid:2480087
Palou A et al. Changes induced in rat plasma composition by lactation. 1982 Arch. Int. Physiol. Biochim. pmid:6186217
Caamaño GJ et al. In vivo lipid and amino acid synthesis from 3-hydroxybutyrate in 15-day-old chick. 1990 Arch. Int. Physiol. Biochim. pmid:1708988
Fulop M et al. Serum beta-hydroxybutyrate measurement in patients with uncontrolled diabetes mellitus. 1999 Arch. Intern. Med. pmid:10030312
Villalobos-Molina R et al. Effect of hypoxia and reoxygenation on metabolic pathways in rat hepatocytes. 1998 Arch. Med. Res. pmid:9775454
Mothes G et al. Regulation of poly(beta-hydroxybutyrate) synthesis in Methylobacterium rhodesianum MB 126 growing on methanol or fructose. 1998 Arch. Microbiol. pmid:9531638
Green LS et al. Isocitrate dehydrogenase and glyoxylate cycle enzyme activities in Bradyrhizobium japonicum under various growth conditions. 1998 Arch. Microbiol. pmid:9560426
Platen H et al. Anaerobic degradation of acetone by Desulfococcus biacutus spec. nov. 1990 Arch. Microbiol. pmid:2244787
Sukdeo N and Charles TC Application of crossover-PCR-mediated deletion-insertion mutagenesis to analysis of the bdhA-xdhA2-xdhB2 mixed-function operon of Sinorhizobium meliloti. 2003 Arch. Microbiol. pmid:12632261
Mothes G et al. Competition between beta-ketothiolase and citrate synthase during poly(beta-hydroxybutyrate) synthesis in Methylobacterium rhodesianum. 1996 Arch. Microbiol. pmid:9082918
Garcia JH et al. [Induced metabolic alterations due to experimental normothermic hepatic ischemia and the hepatoprotector effect of cyclosporin]. 2004 Jan-Mar Arq Gastroenterol pmid:15499426
Halkes CJ et al. Gender differences in postprandial ketone bodies in normolipidemic subjects and in untreated patients with familial combined hyperlipidemia. 2003 Arterioscler. Thromb. Vasc. Biol. pmid:12933534
Koutsari C et al. Exercise prevents the accumulation of triglyceride-rich lipoproteins and their remnants seen when changing to a high-carbohydrate diet. 2001 Arterioscler. Thromb. Vasc. Biol. pmid:11557682
Wu S et al. Study on decellularized porcine aortic valve/poly (3-hydroxybutyrate-co-3-hydroxyhexanoate) hybrid heart valve in sheep model. 2007 Artif Organs pmid:17725696
Ward RA and Wathen RL Utilization of bicarbonate for base repletion in hemodialysis. 1982 Artif Organs pmid:7165554
Kimoto M et al. The effects of PGI2 analog (OP-41483) on perfused porcine liver. 1989 Artif Organs pmid:2669693
Stefanovich V Effect of theophylline administration on ketone bodies level in rat plasma and brain. 1983 Arzneimittelforschung pmid:6684931
Zhou Y et al. Structured triglyceride for parenteral nutrition: meta-analysis of randomized controlled trials. 2006 Asia Pac J Clin Nutr pmid:16837434
Evans K et al. Tissue-specific stable isotope measurements of postprandial lipid metabolism in familial combined hyperlipidaemia. 2008 Atherosclerosis pmid:17466309
Otero P et al. Development of atherosclerosis in the diabetic BALB/c mice. Prevention with Vitamin E administration. 2005 Atherosclerosis pmid:16159598
Potezny N et al. The inhibition of bacterial cell growth by ketone bodies. 1981 Aust J Exp Biol Med Sci pmid:7034705
Rae A et al. A randomised controlled trial of dietary energy restriction in the management of obese women with gestational diabetes. 2000 Aust N Z J Obstet Gynaecol pmid:11194427
Pethick DW et al. Non-esterified long-chain fatty acid metabolism in fed sheep at rest and during exercise. 1987 Aust. J. Biol. Sci. pmid:3662970
DeGaris PJ et al. Effects of increasing days of exposure to prepartum diets on the concentration of certain blood metabolites in dairy cows. 2010 Aust. Vet. J. pmid:20402701
Kennerman E et al. Effect of monensin controlled release capsules on blood metabolites in periparturient dairy cows. 2006 Aust. Vet. J. pmid:16911228
Abe N et al. Effects of sodium monensin on reproductive performance of dairy cattle. II. Effects on metabolites in plasma, resumption of ovarian cyclicity and oestrus in lactating cows. 1994 Aust. Vet. J. pmid:7818435
Cheng B et al. D-beta-hydroxybutyrate inhibits the apoptosis of PC12 cells induced by 6-OHDA in relation to up-regulating the ratio of Bcl-2/Bax mRNA. 2007 Auton Neurosci pmid:17369104
Bruer J et al. Ketone bodies maintain normal cardiac function and myocardial high energy phosphates during insulin-induced hypoglycemia in vivo. 1989 Sep-Oct Basic Res. Cardiol. pmid:2684144
Swithers SE and McCurley M Effects of 2-mercaptoacetate on ingestive behavior in 18- and 21-day-old rats. 2002 Behav. Brain Res. pmid:12429414
Hamadeh ME et al. [Concentrations of metabolically relevant parameters in the blood of highly pregnant ewes]. 1996 Berl. Munch. Tierarztl. Wochenschr. pmid:8721300
Swiatek KR et al. The metabolism of D- and L-3-hydroxybutyrate in developing rat brain. 1984 Biochem Med pmid:6477538
Casazza JP and Veech RL The production of 1,2-propanediol in ethanol treated rats. 1985 Biochem. Biophys. Res. Commun. pmid:4040364
Wei T et al. Protective effects of exogenous β-hydroxybutyrate on paraquat toxicity in rat kidney. 2014 Biochem. Biophys. Res. Commun. pmid:24755084
Butchbach ME et al. Effect of diet on the survival and phenotype of a mouse model for spinal muscular atrophy. 2010 Biochem. Biophys. Res. Commun. pmid:19945425
Ivarsson N et al. AICAR reverses ketone body mediated insulin resistance in isolated oxidative muscle. 2011 Biochem. Biophys. Res. Commun. pmid:21982775
Hildebrandt L et al. Acyl CoA and lipid synthesis from ketone bodies by the extramitochondrial fraction of hepatoma tissue. 1996 Biochem. Biophys. Res. Commun. pmid:8769135
Kabiraj P et al. Nitrosative stress mediated misfolded protein aggregation mitigated by Na-D-β-hydroxybutyrate intervention. 2012 Biochem. Biophys. Res. Commun. pmid:22974977
Weinstein I et al. Secretion of triglyceride and ketogenesis by livers from spontaneous diabetic BB Wistar rats. 1991 Biochem. Biophys. Res. Commun. pmid:2039501
Shimomura Y et al. Protective effect of coenzyme Q10 on exercise-induced muscular injury. 1991 Biochem. Biophys. Res. Commun. pmid:2018527
Gil J et al. Effects of diabetes on fructose 2, 6-P2, glucose 1, 6-P2 and 6-phosphofructo 2-kinase in rat liver. 1986 Biochem. Biophys. Res. Commun. pmid:3010981
Zhang Y et al. 1H NMR-based spectroscopy detects metabolic alterations in serum of patients with early-stage ulcerative colitis. 2013 Biochem. Biophys. Res. Commun. pmid:23510994
Jones L et al. Purification and characterization of D-beta-hydroxybutyrate dehydrogenase expressed in Escherichia coli. 1993 Jul-Aug Biochem. Cell Biol. pmid:8123257
Palmer TN et al. Modulation of branched-chain amino acid oxidation in rat hemidiaphragms in vitro by glucose and ketone bodies. 1985 Biochem. Int. pmid:4062956
Caamaño GJ et al. Ketone body utilization in duodenum. Differential effect of fasting on lipogenesis from acetoacetate and 3-hydroxybutyrate. 1989 Biochem. Int. pmid:2575906
Kümmel L Evidence for possible interrelationship between gluconeogenesis and ketogenesis? 1984 Biochem. Int. pmid:6477611
Linares A et al. Comparative effect of fasting on acetoacetate and D-3-hydroxybutyrate metabolism in the newborn chick. 1992 Biochem. Int. pmid:1482404
Stillwell W and Nahmias S Effect of retinol and retinoic acid on P/O ratios of coupled mitochondria. 1983 Biochem. Int. pmid:6679330
Dynnik VV et al. Stoichiometric traps in the tricarboxylic acid cycle. I. Self-inhibition and triggering phenomena. 1987 Biochem. Int. pmid:3579962
Laker ME and Mayes PA Regulation of 3-hydroxybutyrate formation and secretion of very-low-density-lipoprotein triacylglycerol by perfused livers from fed and starved rats. 1982 Biochem. J. pmid:7150254
Fischer Y et al. Glucose transport and glucose transporter GLUT4 are regulated by product(s) of intermediary metabolism in cardiomyocytes. 1997 Biochem. J. pmid:9032447
Brown GC and Brand MD Proton/electron stoichiometry of mitochondrial complex I estimated from the equilibrium thermodynamic force ratio. 1988 Biochem. J. pmid:2843170
Patel TB and Clark JB Lipogenesis in the brain of suckling rats. Studies on the mechansim of mitochondrial-cytosolic carbon transfer. 1980 Biochem. J. pmid:7406877
Kushnareva Y et al. Complex I-mediated reactive oxygen species generation: modulation by cytochrome c and NAD(P)+ oxidation-reduction state. 2002 Biochem. J. pmid:12180906
Qian D and Brosnan JT Administration of Escherichia coli endotoxin to rat increases liver mass and hepatocyte volume in vivo. 1996 Biochem. J. pmid:8573081
Fernández E and Medina JM Lactate utilization by the neonatal rat brain in vitro. Competition with glucose and 3-hydroxybutyrate. 1986 Biochem. J. pmid:3718483
Hue L et al. Palmitate inhibits liver glycolysis. Involvement of fructose 2,6-bisphosphate in the glucose/fatty acid cycle. 1988 Biochem. J. pmid:3401217
Biden TJ and Taylor KW Effects of ketone bodies on insulin release and islet-cell metabolism in the rat. 1983 Biochem. J. pmid:6309141
Norsten C and Cronholm T Compartmentation of acetyl CoA studied by analysis of tricarboxylic acid cycle acids and 3-hydroxybutyrate in bile of rats given [2,2,2-2H3]ethanol. 1990 Biochem. J. pmid:2405844
Nicholson JK et al. Proton-nuclear-magnetic-resonance studies of serum, plasma and urine from fasting normal and diabetic subjects. 1984 Biochem. J. pmid:6696735
Beech JS et al. Gluconeogenesis and the protection of hepatic intracellular pH during diabetic ketoacidosis in rats. 1989 Biochem. J. pmid:2512912
Tildon JT et al. Differential substrate oxidation by dissociated brain cells and homogenates during development. 1983 Biochem. J. pmid:6651776
Reinhart PH et al. The contribution of both extracellular and intracellular calcium to the action of alpha-adrenergic agonists in perfused rat liver. 1984 Biochem. J. pmid:6743271
Haney PM et al. Turnover of succinyl-CoA:3-oxoacid CoA-transferase in glioma and neuroblastoma cells. Specific influence of acetoacetate in neuroblastoma cells. 1984 Biochem. J. pmid:6594997
Grantham BD and Zammit VA Role of carnitine palmitoyltransferase I in the regulation of hepatic ketogenesis during the onset and reversal of chronic diabetes. 1988 Biochem. J. pmid:3277623
Roeder LM et al. Competition among oxidizable substrates in brains of young and adult rats. Whole homogenates. 1984 Biochem. J. pmid:6426468
Roeder LM et al. Competition among oxidizable substrates in brains of young and adult rats. Dissociated cells. 1984 Biochem. J. pmid:6426469
McKenna MC et al. Competition of glycerol with other oxidizable substrates in rat brain. 1986 Biochem. J. pmid:3099749
Ramirez R et al. Assay of 3-hydroxybutyrate in the picomolar range. 1991 Biochem. Med. Metab. Biol. pmid:1883629
Quevedo-Coli S et al. Alterations in circulating fatty acids and the compartmentation of selected metabolites in women with breast cancer. 1997 Biochem. Mol. Biol. Int. pmid:9043629
Palmer TN et al. Partial oxidation of leucine in skeletal muscle. 1993 Biochem. Mol. Biol. Int. pmid:8495210
Segués T et al. Long-term effects of cafeteria diet feeding on young Wistar rats. 1994 Biochem. Mol. Biol. Int. pmid:7951050
Gómez G et al. 3-Hydroxybutyrate decreases noradrenaline affinity for rat erythrocyte ghost beta 2-adrenergic receptors. 1996 Biochem. Mol. Biol. Int. pmid:8896759
Kruszynska YT and Sherratt HS Glucose kinetics during acute and chronic treatment of rats with 2[6(4-chloro-phenoxy)hexyl]oxirane-2-carboxylate, etomoxir. 1987 Biochem. Pharmacol. pmid:3689429
Knights KM and Drew R The effects of ibuprofen enantiomers on hepatocyte intermediary metabolism and mitochondrial respiration. 1992 Biochem. Pharmacol. pmid:1417953
DeMaster EG and Stevens JM Acute effects of the aldehyde dehydrogenase inhibitors, disulfiram, pargyline and cyanamide, on circulating ketone body levels in the rat. 1988 Biochem. Pharmacol. pmid:3342079
Bolaños JP and Medina JM Effect of valproate on lipogenesis in neonatal rat brain. 1993 Biochem. Pharmacol. pmid:8466548
Harrison MP et al. beta-Hydroxybutyrate: a urinary marker of imipenem induced nephrotoxicity in the cynomolgus monkey detected by high field 1H NMR spectroscopy. 1991 Biochem. Pharmacol. pmid:2039554
Griffin H et al. Changes in plasma lipoprotein metabolism in chicks in response to polychlorinated biphenyls (PCBs). 1991 Biochem. Pharmacol. pmid:1930274
Dubey RK et al. Effects of endosulfan and its metabolites on rat liver mitochondrial respiration and enzyme activities in vitro. 1984 Biochem. Pharmacol. pmid:6149750
Bartelds B et al. Role of ketone bodies in perinatal myocardial energy metabolism. 2001 Biochem. Soc. Trans. pmid:11356176
Jiffri E et al. Altered renal intermediary metabolism and the onset of renal dysfunction in the streptozotocin diabetic rat. 1996 Biochem. Soc. Trans. pmid:8736922