(r)-3-hydroxybutanoic acid

(r)-3-hydroxybutanoic acid is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 2725 references associated with (r)-3-hydroxybutanoic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for (r)-3-hydroxybutanoic acid

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with (r)-3-hydroxybutanoic acid

MeSH term MeSH ID Detail
Congenital Abnormalities D000013 11 associated lipids
Abortion, Spontaneous D000022 12 associated lipids
Abortion, Veterinary D000034 5 associated lipids
Acid-Base Imbalance D000137 3 associated lipids
Acidosis D000138 13 associated lipids
Acromegaly D000172 6 associated lipids
Adenocarcinoma D000230 166 associated lipids
Albuminuria D000419 18 associated lipids
Alcoholic Intoxication D000435 15 associated lipids
Alkalosis D000471 3 associated lipids
Alkalosis, Respiratory D000472 4 associated lipids
Alzheimer Disease D000544 76 associated lipids
Amyotrophic Lateral Sclerosis D000690 11 associated lipids
Anorexia D000855 8 associated lipids
Hypoxia D000860 23 associated lipids
Aortopulmonary Septal Defect D001028 1 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Asphyxia D001237 5 associated lipids
Birth Weight D001724 23 associated lipids
Body Weight D001835 333 associated lipids
Per page 10 20 50 100 | Total 185

PubChem Associated disorders and diseases

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with (r)-3-hydroxybutanoic acid

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Per page 10 20 50 100 | Total 2707
Authors Title Published Journal PubMed Link
Dunger DB et al. Impact of increased growth hormone secretion on carbohydrate metabolism in adolescents with diabetes. 1991 Acta Paediatr Scand Suppl pmid:1723835
Lean IJ et al. Postparturient metabolic and production responses in cows previously exposed to long-term treatment with somatotropin. 1991 J. Dairy Sci. pmid:1744273
Zuniga-Guarjardo S et al. Insulin resistance and action in hypertriglyceridemia. 1991 Diabetes Res. Clin. Pract. pmid:1748063
Arakawa T et al. Effect of ketone body (D-3-hydroxybutyrate) on neural activity and energy metabolism in hippocampal slices of the adult guinea pig. 1991 Neurosci. Lett. pmid:1749516
Watanabe T et al. Serum ketone response to glucagon as a marker of insulin dependency in diabetics. 1991 Diabetes Res. Clin. Pract. pmid:1756681
Miller PS et al. Patterns of nutrient uptake by the mammary glands of lactating dairy cows. 1991 J. Dairy Sci. pmid:1757621
Miller PS et al. Relationship of early lactation and bovine somatotropin on nutrient uptake by cow mammary glands. 1991 J. Dairy Sci. pmid:1757622
Vicario C et al. The fate of lactate in isolated cells from early neonatal rat brain. Comparison with glucose and 3-hydroxybutyrate. 1991 Biochem. Soc. Trans. pmid:1889539
Gagliostro G et al. Duodenal rapeseed oil infusion in early and midlactation cows. 3. Plasma hormones and mammary apparent uptake of metabolites. 1991 J. Dairy Sci. pmid:1894799
Langhans W Hepatic and intestinal handling of metabolites during feeding in rats. 1991 Physiol. Behav. pmid:1896503
Kealey T et al. Intermediary metabolism of the human hair follicle. 1991 Ann. N. Y. Acad. Sci. pmid:1809089
Amiel SA et al. Ketone infusion lowers hormonal responses to hypoglycaemia: evidence for acute cerebral utilization of a non-glucose fuel. 1991 Clin. Sci. pmid:1653662
Elayan IM et al. Malonyl-CoA in skeletal muscle and liver of streptozotocin-diabetic rats. 1991 Proc. Soc. Exp. Biol. Med. pmid:1653960
Thorell JO et al. Synthesis of [1-11C]-beta-hydroxybutyric acid. 1991 Acta Radiol Suppl pmid:1666800
Patel HR et al. A quantitative histochemical study of D-amino acid oxidase activity in rat liver in relationship with feeding conditions. 1991 J. Histochem. Cytochem. pmid:1670580
Marker JC et al. Catecholamines in prevention of hypoglycemia during exercise in humans. 1991 Am. J. Physiol. pmid:1674642
Schroeder H et al. Influence of early chronic phenobarbital treatment on cerebral arteriovenous differences of glucose and ketone bodies in the developing rat. 1991 Int. J. Dev. Neurosci. pmid:1781304
Hiraide A et al. Effect of sodium D-3-hydroxybutyrate on amino acidemia in hemorrhagic hypotension. 1991 Eur Surg Res pmid:1782970
Amiel SA et al. Insulin resistance of puberty: a defect restricted to peripheral glucose metabolism. 1991 J. Clin. Endocrinol. Metab. pmid:1991798
Hiraide A et al. Effect of 3-hydroxybutyrate on posttraumatic metabolism in man. 1991 Surgery pmid:1992551
De Feo P et al. Evidence against important catecholamine compensation for absent glucagon counterregulation. 1991 Am. J. Physiol. pmid:1996624
Wetzel DM and Salpeter MM Fibrillation and accelerated AChR degradation in long-term muscle organ culture. 1991 Muscle Nerve pmid:1944400
Hawkins RA and Mans AM Regional blood-brain barrier transport of ketone bodies in portacaval-shunted rats. 1991 Am. J. Physiol. pmid:1951691
Grootveld M et al. Influence of an intravenous dose of aurothiomalate on the status of low-molecular-mass endogenous metabolites in blood plasma: a proton nuclear magnetic resonance (NMR) study. 1991 Agents Actions Suppl. pmid:1906237
Ruell PA and Gass GC Enzymatic measurement of 3-hydroxybutyrate in extracts of blood without neutralization. 1991 Ann. Clin. Biochem. pmid:1907121
Lynch GP et al. Nitrogen metabolism of lactating ewes fed rumen-protected methionine and lysine. 1991 J. Dairy Sci. pmid:1910058
Orskov L et al. Decreased hepatic glucagon responses in type 1 (insulin-dependent) diabetes mellitus. 1991 Diabetologia pmid:1916058
Larsen S et al. The effect of insulin withdrawal on intermediary metabolism in patients with diabetes secondary to chronic pancreatitis. 1991 Acta Endocrinol. pmid:2028708
Quigley JD et al. Changes in blood glucose, nonesterified fatty acids, and ketones in response to weaning and feed intake in young calves. 1991 J. Dairy Sci. pmid:2030170
Hirsch IB et al. Insulin and glucagon in prevention of hypoglycemia during exercise in humans. 1991 Am. J. Physiol. pmid:2035626
Weinstein I et al. Secretion of triglyceride and ketogenesis by livers from spontaneous diabetic BB Wistar rats. 1991 Biochem. Biophys. Res. Commun. pmid:2039501
Harrison MP et al. beta-Hydroxybutyrate: a urinary marker of imipenem induced nephrotoxicity in the cynomolgus monkey detected by high field 1H NMR spectroscopy. 1991 Biochem. Pharmacol. pmid:2039554
Griffin H et al. Changes in plasma lipoprotein metabolism in chicks in response to polychlorinated biphenyls (PCBs). 1991 Biochem. Pharmacol. pmid:1930274
Svedjeholm R et al. Myocardial uptake of amino acids and other substrates in relation to myocardial oxygen consumption four hours after cardiac operations. 1991 J. Thorac. Cardiovasc. Surg. pmid:2008107
Davis TA et al. Response of muscle protein synthesis to fasting in suckling and weaned rats. 1991 Am. J. Physiol. pmid:1721504
Heller SR and Cryer PE Hypoinsulinemia is not critical to glucose recovery from hypoglycemia in humans. 1991 Am. J. Physiol. pmid:1858873
Inoue K et al. Release of amylin from perfused rat pancreas in response to glucose, arginine, beta-hydroxybutyrate, and gliclazide. 1991 Diabetes pmid:1860552
Clore JN et al. Evidence for dual control mechanism regulating hepatic glucose output in nondiabetic men. 1991 Diabetes pmid:1860555
Cisse M et al. Slow release somatotropin in dairy heifers and cows fed two levels of energy concentrate. 2. Plasma hormones and metabolites. 1991 J. Dairy Sci. pmid:1860980
Ratheiser K et al. Inhibition by etomoxir of carnitine palmitoyltransferase I reduces hepatic glucose production and plasma lipids in non-insulin-dependent diabetes mellitus. 1991 Metab. Clin. Exp. pmid:1943747
Lautenbacher S et al. Dieting and pain sensitivity: a validation of clinical findings. 1991 Physiol. Behav. pmid:1801020
Harding JE and Evans PC beta-Hydroxybutyrate is an alternative substrate for the fetal sheep brain. 1991 J. Dev. Physiol. pmid:1823915
Bleiberg B et al. Determination of plasma lactic acid concentration and specific activity using high-performance liquid chromatography. 1991 J. Chromatogr. pmid:1783635
Rizzo T et al. Correlations between antepartum maternal metabolism and child intelligence. 1991 N. Engl. J. Med. pmid:1881416
Ramirez R et al. Assay of 3-hydroxybutyrate in the picomolar range. 1991 Biochem. Med. Metab. Biol. pmid:1883629
Ruwe PJ et al. Effect of maternal fasting on fetal and placental lipid metabolism in swine. 1991 J. Anim. Sci. pmid:2066303
Philpott MP and Kealey T Metabolic studies on isolated hair follicles: hair follicles engage in aerobic glycolysis and do not demonstrate the glucose fatty acid cycle. 1991 J. Invest. Dermatol. pmid:2045676
Gilbert M et al. Role of free fatty acids in hepatic insulin resistance during late pregnancy in conscious rabbits. 1991 Am. J. Physiol. pmid:2058668
Kim DK et al. Effects of beta-hydroxybutyrate on oxidative metabolism and phosphorylation potential in canine heart in vivo. 1991 Am. J. Physiol. pmid:2058715
McBride MO et al. Bedside blood ketone body monitoring. 1991 Aug-Sep Diabet. Med. pmid:1833124
Simkhovich BZ et al. [The effect of mildronate on carnitine-dependent and carnitine-independent ketogenesis in rats]. 1991 Jul-Aug Farmakol Toksikol pmid:1786824
Shutenko ZhV et al. [Potentiation of the antiketogenic effect of exogenous glucose with the help of the new beta-oxidation inhibitor mildronate--3-(2,2,2-trimethylhydrazine)propionate]. 1991 Mar-Apr Vopr. Med. Khim. pmid:1897198
MacFie J et al. Continuous versus intermittent infusion of fat emulsions during total parenteral nutrition: clinical trial. 1991 Mar-Apr Nutrition pmid:1802203
Lilet H et al. [Lack of benefit from the intermittent administration of insulin in treatment using subcutaneous perfusion pump in type 1 diabetes]. 1991 May-Jun Diabete Metab pmid:1884881
Pal BR et al. Contrasting metabolic effects of continuous and pulsatile growth hormone administration in young adults with type 1 (insulin-dependent) diabetes mellitus. 1992 Diabetologia pmid:1612227
Bostwick JR et al. Phosphoethanolamine enhances high-affinity choline uptake and acetylcholine synthesis in dissociated cell cultures of the rat septal nucleus. 1992 J. Neurochem. pmid:1613501
Vicario C and Medina JM Metabolism of lactate in the rat brain during the early neonatal period. 1992 J. Neurochem. pmid:1613508
Pere MC et al. Hepatic metabolism during fasting-refeeding transition in conscious pregnant rabbits. 1992 Am. J. Physiol. pmid:1616023
Arnould T et al. Effect of hypoxia upon intracellular calcium concentration of human endothelial cells. 1992 J. Cell. Physiol. pmid:1618920
Metcalfe HK et al. Effects of D-3-hydroxybutyrate and acetoacetate on lactate removal in isolated perfused livers from starved and fed rats. 1992 Metab. Clin. Exp. pmid:1556952
Hunsicker KD et al. Effect of starvation or restriction on self-selection of macronutrients in rats. 1992 Physiol. Behav. pmid:1557442
Langhans W et al. [Effect of carbohydrate intake during a long distance run on work capacity and metabolism]. 1992 Z Ernahrungswiss pmid:1585683
Marker JC et al. Attenuated glucose recovery from hypoglycemia in the elderly. 1992 Diabetes pmid:1587394
Farrer M et al. Effect of acute inhibition of lipolysis on operation of the glucose-fatty acid cycle in hepatic cirrhosis. 1992 Metab. Clin. Exp. pmid:1588824
Ferrier B et al. Transport of beta-hydroxybutyrate and acetoacetate along rat nephrons: a micropuncture study. 1992 Am. J. Physiol. pmid:1590421
Schlichtig R et al. Hepatic dysoxia commences during O2 supply dependence. 1992 J. Appl. Physiol. pmid:1592742
Gratama JW et al. Myocardial carbohydrate, ketone, and fatty acid uptake in conscious lambs with aortopulmonary shunts. 1992 Pediatr. Res. pmid:1635842
Eckel RH et al. Dietary substitution of medium-chain triglycerides improves insulin-mediated glucose metabolism in NIDDM subjects. 1992 Diabetes pmid:1568535
Heindorff H et al. Hormonal and neural blockade prevents the postoperative increase in amino acid clearance and urea synthesis. 1992 Surgery pmid:1350868
Takada Y et al. Decrease in arterial ketone body ratio indicating graft dysfunction after liver transplantation. 1992 Eur J Surg pmid:1354500
Chung Y and Jue T 1H NMR observation of redox potential in liver. 1992 Biochemistry pmid:1332750
Bordin D et al. Effect of middle-intensity exercise on carnitine and beta-hydroxybutyrate plasmatic concentration in men and women. 1992 J Sports Med Phys Fitness pmid:1293423
Yokoyama H et al. Transient extreme insulin resistance in shock during diabetic ketoacidosis. 1992 Endocrinol. Jpn. pmid:1294375
Zaidi SS and Bhatnagar VK Spectral evidence for the oxidation of beta-hydroxybutyrate to acetoacetate: diminution of spectra by glucose and chloride. 1992 Indian J. Biochem. Biophys. pmid:1294466
Windisch W and Kirchgessner M [Concentrations of metabolites and hormones in the blood plasma of lactating dairy cows during treatment with recombinant bovine somatotropin (BST)]. 1992 Arch Tierernahr pmid:1296558
Yang N and Jiang Z [The kinetic observation of serum ketone body levels in surgical patients receiving MCT or LCT emulsions]. 1992 Zhongguo Yi Xue Ke Xue Yuan Xue Bao pmid:1303814
Ikeda T et al. Adrenergic mechanism in hyperketonemia in thyrotoxic and starved rats. 1992 Exp. Clin. Endocrinol. pmid:1305070
Johnson AB et al. Effect of increased free fatty acid supply on glucose metabolism and skeletal muscle glycogen synthase activity in normal man. 1992 Clin. Sci. pmid:1311661
Santini FJ et al. Dietary fiber and milk yield, mastication, digestion, and the rate of passage in goats fed alfalfa hay. 1992 J. Dairy Sci. pmid:1311727
Beaufrère B et al. Effects of D-beta-hydroxybutyrate and long- and medium-chain triglycerides on leucine metabolism in humans. 1992 Am. J. Physiol. pmid:1312786
Kennedy CH et al. tert-Butyl hydroperoxide-induced radical production in rat liver mitochondria. 1992 Free Radic. Biol. Med. pmid:1317326
Fulcher GR et al. Acute metabolic and hormonal responses to the inhibition of lipolysis in non-obese patients with non-insulin-dependent (type 2) diabetes mellitus: effects of acipimox. 1992 Clin. Sci. pmid:1317767
Sato N et al. Mechanism of inhibitory action of ketone bodies on the production of reactive oxygen intermediates (ROIS) by polymorphonuclear leukocytes. 1992 Life Sci. pmid:1319534
Briffeuil P et al. Reappraisal of the role of insulin on sodium handling by the kidney: f1fect of intrarenal insulin infusion in the dog. 1992 Eur. J. Clin. Invest. pmid:1425858
Pries A et al. Identification of a lipoamide dehydrogenase gene as second locus affected in poly(3-hydroxybutyric acid)-leaky mutants of Alcaligenes eutrophus. 1992 FEMS Microbiol. Lett. pmid:1427012
Montelongo A et al. Longitudinal study of plasma lipoproteins and hormones during pregnancy in normal and diabetic women. 1992 Diabetes pmid:1446807
Oshida Y et al. Effect of muscle constriction on 3-hydroxybutyrate uptake using the microdialysis technique. 1992 Horm. Metab. Res. pmid:1452121
Linares A et al. Comparative effect of fasting on acetoacetate and D-3-hydroxybutyrate metabolism in the newborn chick. 1992 Biochem. Int. pmid:1482404
Drackley JK et al. Metabolic changes in dairy cows with ketonemia in response to feed restriction and dietary 1,3-butanediol. 1992 J. Dairy Sci. pmid:1500562
Lean IJ et al. Time series cross-correlation analysis of postparturient relationships among serum metabolites and yield variables in Holstein cows. 1992 J. Dairy Sci. pmid:1500586
Bertics SJ et al. Effect of prepartum dry matter intake on liver triglyceride concentration and early lactation. 1992 J. Dairy Sci. pmid:1500587
McCarthy JP et al. Changes in the plasma concentration of gastric inhibitory polypeptide and other metabolites in response to feeding in sheep. 1992 J. Endocrinol. pmid:1402533
Luzi L et al. Lack of feedback inhibition of insulin secretion in denervated human pancreas. 1992 Diabetes pmid:1359986
Fulcher GR et al. Metabolic effects of suppression of nonesterified fatty acid levels with acipimox in obese NIDDM subjects. 1992 Diabetes pmid:1397716
Broussolle C et al. Effects of different lipid substrates on glucose metabolism in normal postabsorptive humans. 1992 Metab. Clin. Exp. pmid:1461133
Goldstein RE et al. The effects of acute elevations in plasma cortisol levels on alanine metabolism in the conscious dog. 1992 Metab. Clin. Exp. pmid:1461135
Harding JE et al. Effects of beta-hydroxybutyrate infusion on hind limb metabolism in fetal sheep. 1992 Am. J. Obstet. Gynecol. pmid:1536251
Quigley JD et al. Postprandial changes of selected blood and ruminal metabolites in ruminating calves fed diets with or without hay. 1992 J. Dairy Sci. pmid:1541733
Weekes TE Influence of experimental hyperthyroidism on insulin action in growing sheep. 1992 Metab. Clin. Exp. pmid:1542262
Rooney DP et al. Insulin action and hepatic glucose cycling in essential hypertension. 1992 Metab. Clin. Exp. pmid:1542271