(r)-3-hydroxybutanoic acid

(r)-3-hydroxybutanoic acid is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 2725 references associated with (r)-3-hydroxybutanoic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for (r)-3-hydroxybutanoic acid

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with (r)-3-hydroxybutanoic acid

MeSH term MeSH ID Detail
Body Weight D001835 333 associated lipids
Lung Neoplasms D008175 171 associated lipids
Adenocarcinoma D000230 166 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Hypertension D006973 115 associated lipids
Glioma D005910 112 associated lipids
Weight Gain D015430 101 associated lipids
Insulin Resistance D007333 99 associated lipids
Hypercholesterolemia D006937 91 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Brain Ischemia D002545 89 associated lipids
Seizures D012640 87 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Alzheimer Disease D000544 76 associated lipids
Hyperlipidemias D006949 73 associated lipids
Carcinoma, Non-Small-Cell Lung D002289 72 associated lipids
Coronary Disease D003327 70 associated lipids
Liver Cirrhosis D008103 67 associated lipids
Reperfusion Injury D015427 65 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Weight Loss D015431 56 associated lipids
Parkinson Disease D010300 53 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Fatty Liver D005234 48 associated lipids
Starvation D013217 47 associated lipids
Coronary Artery Disease D003324 47 associated lipids
Metabolism, Inborn Errors D008661 46 associated lipids
Metabolic Syndrome D024821 44 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Ischemic Attack, Transient D002546 42 associated lipids
Diabetic Nephropathies D003928 39 associated lipids
Diabetic Retinopathy D003930 39 associated lipids
Lung Diseases D008171 37 associated lipids
Liver Cirrhosis, Experimental D008106 36 associated lipids
Epilepsy D004827 35 associated lipids
Spinal Cord Injuries D013119 34 associated lipids
Acute Kidney Injury D058186 34 associated lipids
Neurotoxicity Syndromes D020258 34 associated lipids
Uremia D014511 33 associated lipids
Neurodegenerative Diseases D019636 32 associated lipids
Hypothyroidism D007037 32 associated lipids
Liver Diseases D008107 31 associated lipids
Obesity D009765 29 associated lipids
Hyperinsulinism D006946 27 associated lipids
Mammary Neoplasms, Animal D015674 27 associated lipids
Lipid Metabolism, Inborn Errors D008052 26 associated lipids
Mitochondrial Diseases D028361 25 associated lipids
Cattle Diseases D002418 24 associated lipids
Per page 10 20 50 100 | Total 185

PubChem Associated disorders and diseases

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with (r)-3-hydroxybutanoic acid

Download all related citations
Per page 10 20 50 100 | Total 2707
Authors Title Published Journal PubMed Link
Rosak C et al. Biosynthetic human proinsulin, a new therapeutic compound for diabetics? A comparative study of biosynthetic human proinsulin with biosynthetic human insulin. 1988 Horm. Metab. Res. Suppl. pmid:3056807
Petersen KG et al. Metabolic effects of intravenous proinsulin. 1988 Horm. Metab. Res. Suppl. pmid:3056815
Fink G et al. Pseudoketogenesis in the perfused rat heart. 1988 J. Biol. Chem. pmid:3056937
Møller N et al. Effects of the somatostatin analogue SMS 201-995 (sandostatin) on mouth-to-caecum transit time and absorption of fat and carbohydrates in normal man. 1988 Clin. Sci. pmid:3058374
Arase K et al. Intracerebroventricular infusions of 3-OHB and insulin in a rat model of dietary obesity. 1988 Am. J. Physiol. pmid:3059829
Osuagwuh AI et al. Diurnal variations in the concentration, arteriovenous difference, extraction ratio, and uptake of 3-hydroxybutyrate and plasma free fatty acids in the hind limb of lactating sheep. 1988 J. Dairy Sci. pmid:3170864
Lammerant J et al. Stabilization of left ventricular function with D-(-)-3-hydroxybutyrate after coronary occlusion in the intact dog. 1988 J. Mol. Cell. Cardiol. pmid:3172248
Rett K et al. Inhibition of muscular ketone extraction by lipid infusion in man. 1988 Horm. Metab. Res. pmid:3181868
De Feo P et al. Modest decrements in plasma glucose concentration cause early impairment in cognitive function and later activation of glucose counterregulation in the absence of hypoglycemic symptoms in normal man. 1988 J. Clin. Invest. pmid:3403713
Laessle RG et al. Depression as a correlate of starvation in patients with eating disorders. 1988 Biol. Psychiatry pmid:3370268
Phillips LS et al. Nutrition and somatomedin. XVI: Somatomedins and somatomedin inhibitors in fasted and refed rats. 1988 Metab. Clin. Exp. pmid:2449597
Mansell PI and MacDonald IA The effect of underfeeding on the physiological response to food ingestion in normal weight women. 1988 Br. J. Nutr. pmid:3044444
Des Rosiers C et al. Interference of 3-hydroxyisobutyrate with measurements of ketone body concentration and isotopic enrichment by gas chromatography-mass spectrometry. 1988 Anal. Biochem. pmid:3189805
Hamanoue M et al. [Research on liver function before and after surgery by the relation of artery blood ketone body ratio and beta-hydroxybutyrate: preliminary report]. 1988 Nihon Geka Gakkai Zasshi pmid:3200245
Mikines KJ et al. Postexercise dose-response relationship between plasma glucose and insulin secretion. 1988 J. Appl. Physiol. pmid:3284873
Stewart JK et al. Effects of branched-chain amino acids on postprandial 3-OH butyrate and glucagon in the baboon. 1988 Metab. Clin. Exp. pmid:3285128
Spanheimer RG Direct inhibition of collagen production in vitro by diabetic rat serum. 1988 Metab. Clin. Exp. pmid:3285135
Gutiérrez J et al. Seasonal variations of insulin and some metabolites in dogfish plasma, Scyliorhinus canicula, L. 1988 Gen. Comp. Endocrinol. pmid:3286367
Tuttle KR et al. Glucagon, not insulin, may play a secondary role in defense against hypoglycemia during exercise. 1988 Am. J. Physiol. pmid:3287952
Testar X et al. Comparative metabolic effects of chronic ethanol intake and undernutrition in pregnant rats and their fetuses. 1988 Alcohol. Clin. Exp. Res. pmid:3287981
Vahed YA et al. beta-Adrenergic blockade counteracts starvational ketosis, but aggravates post-exercise ketosis in non-athletes. 1988 J. Endocrinol. pmid:2903899
Leiter LA et al. Severe metabolic acidosis induced in a patient during fasting by KCl administration. 1988 Clin Invest Med pmid:2844461
Pontes Rde C et al. Concentrations of ketone bodies in the blood of the green lizard Ameiva ameiva (Teiidae) in different physiological situations. 1988 Comp Biochem Physiol A Comp Physiol pmid:2896561
McCall AL et al. Effects of hypoglycemia and diabetes on fuel metabolism by rat brain microvessels. 1988 Am. J. Physiol. pmid:2964787
Vissing J et al. Role of metabolic feedback regulation in glucose production of running rats. 1988 Am. J. Physiol. pmid:3046377
Pschera H et al. Interrelation between glucose, insulin, C-peptide and 3-hydroxybutyrate in plasma and amniotic fluid in last trimester diabetic women without residual betacell function. 1988 Horm. Metab. Res. pmid:3053389
Flatt PR et al. Effects of diet-induced ketosis in rats with hypoglycaemia due to a serially transplantable insulinoma. 1987 Sep-Oct Diabete Metab pmid:2828127
Massi Benedetti M et al. Hormonal and metabolic responses in brittle diabetic patients during feedback intravenous insulin infusion. 1987 Nov-Dec Diabetes Res. Clin. Pract. pmid:3311678
Scheen AJ et al. U-100 insulin gives some protection against metabolic deterioration due to CSII interruption. 1987 Nov-Dec Diabetes Care pmid:3322727
Binimelis J et al. Plasma immunoreactive somatostatin is elevated in diabetic ketoacidosis and correlates with plasma non-esterified fatty acid concentration. 1987 May-Jun Diabet. Med. pmid:2886248
Lundy EF et al. Elevated blood ketone and glucagon levels cannot account for 1,3-butanediol induced cerebral protection in the Levine rat. 1987 Jan-Feb Stroke pmid:3810756
Steel JM et al. Observations on the metabolic basis for altered insulin dose distribution in diabetic pregnancy. 1987 Jan-Feb Diabetes Res. Clin. Pract. pmid:3545727
Brambilla P et al. Risk of ketosis during intensive insulin therapy in pre-school-age diabetic children. 1987 Jan-Feb Diabetes Care pmid:3105985
Storms FE et al. Comparison of efficacy of human and porcine insulin in treatment of diabetic ketoacidosis. 1987 Jan-Feb Diabetes Care pmid:3105986
Lowell BB and Goodman MN Protein sparing in skeletal muscle during prolonged starvation. Dependence on lipid fuel availability. 1987 Diabetes pmid:3792662
Bray GA et al. Brain uptake of ketones in rats with differing susceptibility to dietary obesity. 1987 Metab. Clin. Exp. pmid:3796295
Beavis AD Upper and lower limits of the charge translocation stoichiometry of mitochondrial electron transport. 1987 J. Biol. Chem. pmid:3571252
Lövgren B and Hellstrand P Functional role of aerobic glycolysis in rat portal vein. 1987 Acta Physiol. Scand. pmid:3577809
Dynnik VV et al. Stoichiometric traps in the tricarboxylic acid cycle. I. Self-inhibition and triggering phenomena. 1987 Biochem. Int. pmid:3579962
Park GD et al. Sustained reductions in oxipurinol renal clearance during a restricted diet. 1987 Clin. Pharmacol. Ther. pmid:3581647
Metzger BE and Freinkel N Accelerated starvation in pregnancy: implications for dietary treatment of obesity and gestational diabetes mellitus. 1987 Biol. Neonate pmid:3552061
Richtsmeier WJ et al. In vivo nutrient uptake by head and neck cancers. 1987 Cancer Res. pmid:3621209
Barac-Nieto M D(-)3-hydroxybutyrate cotransport with Na in rat renal brush border membrane vesicles. 1987 Pflugers Arch. pmid:3588250
Desai SP et al. Branched-chain amino acid administration in surgical patients. Effects on amino acid and fuel substrate profiles. 1987 Arch Surg pmid:3592966
Hollingsworth RI et al. Reexamination of the presence and linkage of 3-hydroxybutyryl substituents in the acidic capsular polysaccharide of Rhizobium trifolii 0403. 1987 J. Bacteriol. pmid:3597324
Matsuo M et al. Urinary evidence of disturbance of mitochondrial respiratory chain in Reye syndrome. 1987 J. Pediatr. pmid:3598782
Sanjak M et al. Physiologic and metabolic response to progressive and prolonged exercise in amyotrophic lateral sclerosis. 1987 Neurology pmid:3601086
Fioretto P et al. Glomerular filtration rate is increased in man by the infusion of both D,L-3-hydroxybutyric acid and sodium D,L-3-hydroxybutyrate. 1987 J. Clin. Endocrinol. Metab. pmid:3298305
Goodman MN and del Pilar Gomez M Decreased myofibrillar proteolysis after refeeding requires dietary protein or amino acids. 1987 Am. J. Physiol. pmid:3300365
Fuessl HS et al. The effect of a long-acting somatostatin analogue (SMS 201-995) on intermediary metabolism and gut hormones after a test meal in normal subjects. 1987 Aliment. Pharmacol. Ther. pmid:2979676