(r)-3-hydroxybutanoic acid

(r)-3-hydroxybutanoic acid is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 2725 references associated with (r)-3-hydroxybutanoic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for (r)-3-hydroxybutanoic acid

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with (r)-3-hydroxybutanoic acid

MeSH term MeSH ID Detail
Congenital Abnormalities D000013 11 associated lipids
Abortion, Spontaneous D000022 12 associated lipids
Abortion, Veterinary D000034 5 associated lipids
Acid-Base Imbalance D000137 3 associated lipids
Acidosis D000138 13 associated lipids
Acromegaly D000172 6 associated lipids
Adenocarcinoma D000230 166 associated lipids
Albuminuria D000419 18 associated lipids
Alcoholic Intoxication D000435 15 associated lipids
Alkalosis D000471 3 associated lipids
Alkalosis, Respiratory D000472 4 associated lipids
Alzheimer Disease D000544 76 associated lipids
Amyotrophic Lateral Sclerosis D000690 11 associated lipids
Anorexia D000855 8 associated lipids
Hypoxia D000860 23 associated lipids
Aortopulmonary Septal Defect D001028 1 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Asphyxia D001237 5 associated lipids
Birth Weight D001724 23 associated lipids
Body Weight D001835 333 associated lipids
Brain Neoplasms D001932 15 associated lipids
Bulimia D002032 3 associated lipids
Cachexia D002100 21 associated lipids
Carcinoma 256, Walker D002279 22 associated lipids
Carcinoma, Non-Small-Cell Lung D002289 72 associated lipids
Cardiac Output, Low D002303 2 associated lipids
Cat Diseases D002371 12 associated lipids
Cattle Diseases D002418 24 associated lipids
Brain Ischemia D002545 89 associated lipids
Ischemic Attack, Transient D002546 42 associated lipids
Cholestasis D002779 23 associated lipids
Corneal Diseases D003316 13 associated lipids
Coronary Artery Disease D003324 47 associated lipids
Coronary Disease D003327 70 associated lipids
Cysticercosis D003551 2 associated lipids
Death, Sudden D003645 12 associated lipids
Dehydration D003681 11 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Diabetic Nephropathies D003928 39 associated lipids
Diabetic Retinopathy D003930 39 associated lipids
Dwarfism, Pituitary D004393 3 associated lipids
Dystocia D004420 3 associated lipids
Endometritis D004716 6 associated lipids
Epilepsy D004827 35 associated lipids
Epilepsy, Generalized D004829 2 associated lipids
Escherichia coli Infections D004927 17 associated lipids
Exostoses, Multiple Hereditary D005097 3 associated lipids
Per page 10 20 50 100 | Total 185

PubChem Associated disorders and diseases

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with (r)-3-hydroxybutanoic acid

Download all related citations
Per page 10 20 50 100 | Total 2707
Authors Title Published Journal PubMed Link
Casazza JP and Veech RL The production of 1,2-propanediol in ethanol treated rats. 1985 Biochem. Biophys. Res. Commun. pmid:4040364
Wei T et al. Protective effects of exogenous β-hydroxybutyrate on paraquat toxicity in rat kidney. 2014 Biochem. Biophys. Res. Commun. pmid:24755084
Butchbach ME et al. Effect of diet on the survival and phenotype of a mouse model for spinal muscular atrophy. 2010 Biochem. Biophys. Res. Commun. pmid:19945425
Ivarsson N et al. AICAR reverses ketone body mediated insulin resistance in isolated oxidative muscle. 2011 Biochem. Biophys. Res. Commun. pmid:21982775
Hildebrandt L et al. Acyl CoA and lipid synthesis from ketone bodies by the extramitochondrial fraction of hepatoma tissue. 1996 Biochem. Biophys. Res. Commun. pmid:8769135
Kabiraj P et al. Nitrosative stress mediated misfolded protein aggregation mitigated by Na-D-β-hydroxybutyrate intervention. 2012 Biochem. Biophys. Res. Commun. pmid:22974977
Weinstein I et al. Secretion of triglyceride and ketogenesis by livers from spontaneous diabetic BB Wistar rats. 1991 Biochem. Biophys. Res. Commun. pmid:2039501
Shimomura Y et al. Protective effect of coenzyme Q10 on exercise-induced muscular injury. 1991 Biochem. Biophys. Res. Commun. pmid:2018527
Gil J et al. Effects of diabetes on fructose 2, 6-P2, glucose 1, 6-P2 and 6-phosphofructo 2-kinase in rat liver. 1986 Biochem. Biophys. Res. Commun. pmid:3010981
Zhang Y et al. 1H NMR-based spectroscopy detects metabolic alterations in serum of patients with early-stage ulcerative colitis. 2013 Biochem. Biophys. Res. Commun. pmid:23510994
Jones L et al. Purification and characterization of D-beta-hydroxybutyrate dehydrogenase expressed in Escherichia coli. 1993 Jul-Aug Biochem. Cell Biol. pmid:8123257
Palmer TN et al. Modulation of branched-chain amino acid oxidation in rat hemidiaphragms in vitro by glucose and ketone bodies. 1985 Biochem. Int. pmid:4062956
Caamaño GJ et al. Ketone body utilization in duodenum. Differential effect of fasting on lipogenesis from acetoacetate and 3-hydroxybutyrate. 1989 Biochem. Int. pmid:2575906
Kümmel L Evidence for possible interrelationship between gluconeogenesis and ketogenesis? 1984 Biochem. Int. pmid:6477611
Linares A et al. Comparative effect of fasting on acetoacetate and D-3-hydroxybutyrate metabolism in the newborn chick. 1992 Biochem. Int. pmid:1482404
Stillwell W and Nahmias S Effect of retinol and retinoic acid on P/O ratios of coupled mitochondria. 1983 Biochem. Int. pmid:6679330
Dynnik VV et al. Stoichiometric traps in the tricarboxylic acid cycle. I. Self-inhibition and triggering phenomena. 1987 Biochem. Int. pmid:3579962
Laker ME and Mayes PA Regulation of 3-hydroxybutyrate formation and secretion of very-low-density-lipoprotein triacylglycerol by perfused livers from fed and starved rats. 1982 Biochem. J. pmid:7150254
Fischer Y et al. Glucose transport and glucose transporter GLUT4 are regulated by product(s) of intermediary metabolism in cardiomyocytes. 1997 Biochem. J. pmid:9032447
Brown GC and Brand MD Proton/electron stoichiometry of mitochondrial complex I estimated from the equilibrium thermodynamic force ratio. 1988 Biochem. J. pmid:2843170
Patel TB and Clark JB Lipogenesis in the brain of suckling rats. Studies on the mechansim of mitochondrial-cytosolic carbon transfer. 1980 Biochem. J. pmid:7406877
Kushnareva Y et al. Complex I-mediated reactive oxygen species generation: modulation by cytochrome c and NAD(P)+ oxidation-reduction state. 2002 Biochem. J. pmid:12180906
Qian D and Brosnan JT Administration of Escherichia coli endotoxin to rat increases liver mass and hepatocyte volume in vivo. 1996 Biochem. J. pmid:8573081
Fernández E and Medina JM Lactate utilization by the neonatal rat brain in vitro. Competition with glucose and 3-hydroxybutyrate. 1986 Biochem. J. pmid:3718483
Hue L et al. Palmitate inhibits liver glycolysis. Involvement of fructose 2,6-bisphosphate in the glucose/fatty acid cycle. 1988 Biochem. J. pmid:3401217
Biden TJ and Taylor KW Effects of ketone bodies on insulin release and islet-cell metabolism in the rat. 1983 Biochem. J. pmid:6309141
Norsten C and Cronholm T Compartmentation of acetyl CoA studied by analysis of tricarboxylic acid cycle acids and 3-hydroxybutyrate in bile of rats given [2,2,2-2H3]ethanol. 1990 Biochem. J. pmid:2405844
Nicholson JK et al. Proton-nuclear-magnetic-resonance studies of serum, plasma and urine from fasting normal and diabetic subjects. 1984 Biochem. J. pmid:6696735
Beech JS et al. Gluconeogenesis and the protection of hepatic intracellular pH during diabetic ketoacidosis in rats. 1989 Biochem. J. pmid:2512912
Tildon JT et al. Differential substrate oxidation by dissociated brain cells and homogenates during development. 1983 Biochem. J. pmid:6651776
Reinhart PH et al. The contribution of both extracellular and intracellular calcium to the action of alpha-adrenergic agonists in perfused rat liver. 1984 Biochem. J. pmid:6743271
Haney PM et al. Turnover of succinyl-CoA:3-oxoacid CoA-transferase in glioma and neuroblastoma cells. Specific influence of acetoacetate in neuroblastoma cells. 1984 Biochem. J. pmid:6594997
Grantham BD and Zammit VA Role of carnitine palmitoyltransferase I in the regulation of hepatic ketogenesis during the onset and reversal of chronic diabetes. 1988 Biochem. J. pmid:3277623
Roeder LM et al. Competition among oxidizable substrates in brains of young and adult rats. Whole homogenates. 1984 Biochem. J. pmid:6426468
Roeder LM et al. Competition among oxidizable substrates in brains of young and adult rats. Dissociated cells. 1984 Biochem. J. pmid:6426469
McKenna MC et al. Competition of glycerol with other oxidizable substrates in rat brain. 1986 Biochem. J. pmid:3099749
Ramirez R et al. Assay of 3-hydroxybutyrate in the picomolar range. 1991 Biochem. Med. Metab. Biol. pmid:1883629
Quevedo-Coli S et al. Alterations in circulating fatty acids and the compartmentation of selected metabolites in women with breast cancer. 1997 Biochem. Mol. Biol. Int. pmid:9043629
Palmer TN et al. Partial oxidation of leucine in skeletal muscle. 1993 Biochem. Mol. Biol. Int. pmid:8495210
Segués T et al. Long-term effects of cafeteria diet feeding on young Wistar rats. 1994 Biochem. Mol. Biol. Int. pmid:7951050
Gómez G et al. 3-Hydroxybutyrate decreases noradrenaline affinity for rat erythrocyte ghost beta 2-adrenergic receptors. 1996 Biochem. Mol. Biol. Int. pmid:8896759
Kruszynska YT and Sherratt HS Glucose kinetics during acute and chronic treatment of rats with 2[6(4-chloro-phenoxy)hexyl]oxirane-2-carboxylate, etomoxir. 1987 Biochem. Pharmacol. pmid:3689429
Knights KM and Drew R The effects of ibuprofen enantiomers on hepatocyte intermediary metabolism and mitochondrial respiration. 1992 Biochem. Pharmacol. pmid:1417953
DeMaster EG and Stevens JM Acute effects of the aldehyde dehydrogenase inhibitors, disulfiram, pargyline and cyanamide, on circulating ketone body levels in the rat. 1988 Biochem. Pharmacol. pmid:3342079
Bolaños JP and Medina JM Effect of valproate on lipogenesis in neonatal rat brain. 1993 Biochem. Pharmacol. pmid:8466548
Harrison MP et al. beta-Hydroxybutyrate: a urinary marker of imipenem induced nephrotoxicity in the cynomolgus monkey detected by high field 1H NMR spectroscopy. 1991 Biochem. Pharmacol. pmid:2039554
Griffin H et al. Changes in plasma lipoprotein metabolism in chicks in response to polychlorinated biphenyls (PCBs). 1991 Biochem. Pharmacol. pmid:1930274
Dubey RK et al. Effects of endosulfan and its metabolites on rat liver mitochondrial respiration and enzyme activities in vitro. 1984 Biochem. Pharmacol. pmid:6149750
Vicario C et al. The fate of lactate in isolated cells from early neonatal rat brain. Comparison with glucose and 3-hydroxybutyrate. 1991 Biochem. Soc. Trans. pmid:1889539
Faulkner A and Pollock HT Recovery of mammary function in the lactating goat after refeeding. 1990 Biochem. Soc. Trans. pmid:2083790